astressin has been researched along with Hyperphagia* in 1 studies
1 other study(ies) available for astressin and Hyperphagia
| Article | Year |
|---|---|
Intracerebroventricular urocortin 3 counteracts central acyl ghrelin-induced hyperphagic and gastroprokinetic effects via CRF receptor 2 in rats.
Urocortin 3 is a key neuromodulator in the regulation of stress, anxiety, food intake, gut motility, and energy homeostasis, while ghrelin elicits feeding behavior and enhances gastric emptying, adiposity, and positive energy balance. However, the interplays between urocortin 3 and ghrelin on food intake and gastric emptying remain uninvestigated.. We examined the differential effects of central. ICV infusion of urocortin 3 opposed central acyl ghrelin-elicited hyperphagia via CRF receptor 2 in satiated rats. ICV injection of. ICV-infused urocortin 3 counteracts central acyl ghrelin-induced hyperphagic and gastroprokinetic effects via CRF receptor 2 in rats. Our results clearly showed that enhancing ghrelin and blocking CRF receptor 2 signaling in the brain accelerated gastric emptying, which provided important clues for a new therapeutic avenue in ameliorating anorexia and gastric ileus found in various chronic wasting disorders. Topics: Animals; Catheters; Corticotropin-Releasing Hormone; Eating; Gastric Emptying; Ghrelin; Hyperphagia; Infusions, Intraventricular; Male; Peptide Fragments; Rats; Receptors, Corticotropin-Releasing Hormone; Urocortins | 2016 |