astragaloside a has been researched along with Innate Inflammatory Response in 46 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 21 (45.65) | 24.3611 |
| 2020's | 25 (54.35) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, J; Xu, S | 1 |
| He, Y; Huang, D; Li, S; Pei, C; Shi, S; Wang, F; Wang, M; Wang, X; Wang, Y; Wang, Z; Wu, Y; Xiao, W | 1 |
| Fan, J; Jia, F; Liu, Y; Zhou, X | 1 |
| Gao, Q; Li, Y; Pan, L; Zhang, X | 1 |
| Chu, X; Deng, W; Guo, X; Huang, Q; Tian, Y; Xue, Y | 1 |
| Chu, W; Dong, JJ; Jin, XJ; Li, CH; Li, GQ; Li, JJ; Li, JW; Li, L; Li, YL; Liu, YQ; Zhang, JB; Zhang, M | 1 |
| Baoping, S; Jie, Z; Lili, C; Xiaoqing, D; Xinyan, LI; Yanping, D; Yifan, MA | 1 |
| Li, L; Li, Y; Luo, Y; Meng, X; Pan, G; Zhang, B; Zhang, H; Zhang, Y | 1 |
| Kang, Z; Tang, B; Wang, L; Xiao, L; Xiao, Q | 1 |
| Cao, A; Guo, H; Shen, Q; Su, X; Wang, H; Wang, L; Wang, Y; Yao, X; Zhou, Y; Zhu, B | 1 |
| Chen, L; Chen, Y; Dong, S; He, C; Jiang, S; Tao, S; Tian, L | 1 |
| Guan, J; Guan, R; Guo, X; Li, L; Lin, R; Ma, H; Mao, C; Qu, Z; Wang, F | 1 |
| Bade, R; Bao, M; Borjigidai, A; Cheng, Y; Liu, H; Shao, G; Tsambaa, B | 1 |
| Chen, Y; Li, P; Liang, J; Luo, X; Wang, Q; Xie, X; Yang, C; Zhang, M; Zhou, L | 1 |
| Chen, X; Gao, W; Gu, M; Hu, S; Huang, C; Lin, H; Lin, J; Pan, X; Shao, Z; Tian, N; Wang, B; Wang, X; Wu, Y; Zhang, X; Zheng, X; Zhou, Y | 1 |
| Bai, XH; Chen, JK; Chen, LQ; Guo, MK; Li, JQ; Li, L; Su, SM | 1 |
| Ji, T; Li, W; Wang, Z; Zhang, J; Zhang, Y; Zhu, Y | 1 |
| Chen, Z; Cui, J; Fan, Z; Guo, B; Hu, J; Liu, Y; Shen, J; Wang, Y; Wu, Y; Xie, L | 1 |
| Cao, W; Jiang, J; Tao, C; Xuan, C; Zhang, Y | 1 |
| Abulikemu, Z; Aierken, R; Dilixiati, N; Huang, Y; Li, XY; Sui, S; Tuerxun, D; Zhang, YM | 1 |
| Lu, M; Sun, T; Sun, Y; Wang, H | 1 |
| Guo, L; Jiao, Y; Jin, H; Kim, SC; Li, X; Liu, J; Ma, Y; Shen, L; Zhao, R; Zhou, Z | 1 |
| Guan, Z; Li, Y; Lu, Y; Pei, B; Sun, D; Wang, X; Xu, J; Yuan, L; Zhang, X | 1 |
| Chen, BJ; Han, SS; Hou, J; Liu, FY; Sun, CB; Wen, J; Xiong, L; Yan, JY; Yang, ZS; Ying, Y; Yu, JZ; Zhang, SQ | 1 |
| Chai, YH; Chen, YZ; Gao, J; Jiang, ZB; Li, W; Luo, YF | 1 |
| Cao, T; Chen, Y; Dong, Z; Huang, G; Peng, Y; Yang, Z; Yuan, Z; Zhang, Y; Zhou, J | 1 |
| Li, C; Li, D; Liu, F; Yang, F; Yang, T | 1 |
| Bi, Y; Jiang, P; Li, X; Ma, D; Wang, X; Wang, Y; Yang, J | 1 |
| Liu, HB; Liu, ZH; Wang, J | 1 |
| Deng, J; Ma, SP; Ma, ZQ; Ruan, J; Song, MT; Zhang, RY | 1 |
| Pan, H; Rui, R; Sun, B; Wang, X; Zhang, L | 1 |
| Fang, Z; He, Y; Hu, M; Jiang, A; Lin, Y; Liu, M; Shen, G; Wang, L; Wang, Q; Ye, S; You, L | 1 |
| Chang, X; Xia, Q; Yang, P; Yao, L; Zhou, Y | 1 |
| Li, J; Zhang, X; Zhu, Z | 1 |
| Chen, J; Chen, Y; Gui, D; Guo, Y; Huang, J; Liu, X; Wang, N; Xiao, W | 1 |
| Du, M; Gao, Y; He, Y; Liu, H; Wang, H; Wang, Z; Wu, X | 1 |
| Huang, X; Song, G; Tang, L; Wang, F | 1 |
| Frei, B; Zhang, WJ | 1 |
| Jiang, TM; Li, YM; Lu, J; Wang, Y; Zeng, S; Zhao, P | 1 |
| Deng, BX; Deng, CQ; Ding, H; Huang, XP; Lu, JD; Tang, YH | 1 |
| Fu, BD; Fu, YX; Guo, X; Shen, HQ; Wei, XB; Wu, SC; Yi, PF; Zhang, C; Zhang, LY | 1 |
| Sun, LF; Yang, H; Yu, WN | 1 |
| Chen, C; Gong, X; Shan, G; Sun, X; Yang, Y; Yao, Q; Zhou, X | 1 |
| Bao, KF; Gui, LL; Hong, M; Jiang, GR; Liu, HL; Tao, Y; Wang, XY; Wei, X; Yu, X | 1 |
| Deng, X; Fang, F; Li, H; Li, M; Ma, S | 1 |
| Sun, S; Sun, Y; Wang, S; Yuan, X | 1 |
1 review(s) available for astragaloside a and Innate Inflammatory Response
| Article | Year |
|---|---|
The Molecular Basis of the Anti-Inflammatory Property of Astragaloside IV for the Treatment of Diabetes and Its Complications.
Topics: Anti-Inflammatory Agents; Antioxidants; Diabetes Mellitus; Humans; Inflammation; Saponins | 2023 |
45 other study(ies) available for astragaloside a and Innate Inflammatory Response
| Article | Year |
|---|---|
Astragaloside IV suppresses histamine-induced inflammatory factors and mucin 5 subtype AC overproduction in nasal epithelial cells via regulation of inflammation-related genes.
Topics: Cells, Cultured; Cytokines; Epithelial Cells; Histamine; Histamine Antagonists; Humans; Inflammation; Mucin 5AC; Nasal Mucosa; Rhinitis, Allergic; Saponins; Triterpenes | 2021 |
Astragaloside IV pre-treatment attenuates PM2.5-induced lung injury in rats: Impact on autophagy, apoptosis and inflammation.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Autophagy; Inflammation; Lung Injury; Particulate Matter; Rats; Saponins; Triterpenes | 2022 |
Astragalus polysaccharides and astragaloside IV alleviate inflammation in bovine mammary epithelial cells by regulating Wnt/β-catenin signaling pathway.
Topics: Animals; Astragalus Plant; beta Catenin; Cattle; Epithelial Cells; Inflammation; Lipopolysaccharides; Polysaccharides; Saponins; Triterpenes; Wnt Signaling Pathway | 2022 |
Astragaloside IV attenuates high glucose-induced human keratinocytes injury via TGF-β/Smad signaling pathway.
Topics: Glucose; Humans; Inflammation; Keratinocytes; Signal Transduction; Transforming Growth Factor beta | 2022 |
Astragaloside IV attenuates IL-1β-induced intervertebral disc degeneration through inhibition of the NF-κB pathway.
Topics: Animals; Cells, Cultured; Inflammation; Interleukin-1beta; Intervertebral Disc; Intervertebral Disc Degeneration; Low Back Pain; NF-kappa B; Rats | 2022 |
Astragaloside IV alleviates cytarabine-induced intestinal mucositis by remodeling macrophage polarization through AKT signaling.
Topics: Animals; Cytarabine; Inflammation; Lipopolysaccharides; Macrophages; Membrane Proteins; Mice; Molecular Docking Simulation; Mucositis; Proto-Oncogene Proteins c-akt | 2023 |
Astragaloside IV plays a role in reducing radiation-induced liver inflammation in mice by inhibiting thioredoxin-interacting protein/nod-like receptor protein 3 signaling pathway.
Topics: Animals; Hepatitis; Inflammasomes; Inflammation; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; Signal Transduction; Thioredoxins | 2023 |
The combination of astragaloside IV and Panax notoginseng saponins attenuates cerebral ischaemia-reperfusion injury in rats through ferroptosis and inflammation inhibition via activating Nrf2.
Topics: Animals; Ferroptosis; Inflammation; NF-E2-Related Factor 2; Panax notoginseng; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Saponins | 2023 |
Astragaloside IV attenuates high glucose-induced NF-κB-mediated inflammation through activation of PI3K/AKT-ERK-dependent Nrf2/ARE signaling pathway in glomerular mesangial cells.
Topics: Antioxidants; Cytokines; Glucose; Humans; Inflammation; Mesangial Cells; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction | 2023 |
Astragaloside IV regulates TL1A and NF-κB signal pathway to affect inflammation in necrotizing enterocolitis.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Enterocolitis, Necrotizing; Inflammation; Ligands; NF-kappa B; Rats; Rats, Sprague-Dawley; Signal Transduction | 2023 |
Astragaloside IV alleviates lung inflammation in Klebsiella pneumonia rats by suppressing TGF-β1/Smad pathway.
Topics: Animals; Cytokines; Inflammation; Klebsiella pneumoniae; NF-KappaB Inhibitor alpha; Pneumonia; Rats; Transforming Growth Factor beta1 | 2023 |
Astragaloside IV against Alzheimer's disease via microglia-mediated neuroinflammation using network pharmacology and experimental validation.
Topics: Alzheimer Disease; ErbB Receptors; Humans; Inflammation; Microglia; Molecular Docking Simulation; Network Pharmacology; Neuroinflammatory Diseases; Proto-Oncogene Proteins c-bcl-2; Saponins; Triterpenes | 2023 |
Astragaloside IV inhibits AOM/DSS-induced colitis-associated tumorigenesis via activation of PPARγ signaling in mice.
Topics: Animals; Azoxymethane; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Dextran Sulfate; Disease Models, Animal; Inflammation; Mice; Mice, Inbred C57BL; PPAR gamma; Reactive Oxygen Species | 2023 |
Dual regulation of microglia and neurons by Astragaloside IV-mediated mTORC1 suppression promotes functional recovery after acute spinal cord injury.
Topics: Animals; Apoptosis; Autophagy; Cell Polarity; Cells, Cultured; Disease Models, Animal; Female; Inflammation; Macrophages; Mechanistic Target of Rapamycin Complex 1; Microglia; Neurons; Rats; Rats, Sprague-Dawley; Recovery of Function; Saponins; Signal Transduction; Spinal Cord Injuries; Triterpenes | 2020 |
Astragaloside IV ameliorates intermittent hypoxia-induced inflammatory dysfunction by suppressing MAPK/NF-κB signalling pathways in Beas-2B cells.
Topics: Cells, Cultured; Humans; Hypoxia; Inflammation; Lung; MAP Kinase Signaling System; NF-kappaB-Inducing Kinase; Protein Serine-Threonine Kinases; Respiratory Mucosa; Saponins; Sleep Apnea, Obstructive; Triterpenes | 2020 |
Protective effects of AS-IV on diabetic cardiomyopathy by improving myocardial lipid metabolism in rat models of T2DM.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Diet, High-Fat; Fibrosis; Inflammation; Lipid Metabolism; Male; Myocardium; Rats; Saponins; Triterpenes | 2020 |
Astragaloside IV protects human cardiomyocytes from hypoxia/reoxygenation injury by regulating miR-101a.
Topics: Apoptosis; Cell Hypoxia; Cell Proliferation; Cell Survival; Computational Biology; Gene Expression Profiling; Humans; Inflammation; L-Lactate Dehydrogenase; Malondialdehyde; MAP Kinase Signaling System; MicroRNAs; Myocardial Reperfusion Injury; Myocytes, Cardiac; Receptor, Transforming Growth Factor-beta Type I; Regeneration; Saponins; Signal Transduction; Superoxide Dismutase; Toll-Like Receptor 2; Triterpenes | 2020 |
Transcriptomic Analysis Reveals the Protection of Astragaloside IV against Diabetic Nephropathy by Modulating Inflammation.
Topics: Animals; Collagen Type IV; Cytokines; Diabetic Nephropathies; Fibronectins; Fibrosis; Gene Expression Profiling; Glycation End Products, Advanced; Inflammation; Inflammation Mediators; Male; NLR Proteins; Podocytes; Protective Agents; Rats, Sprague-Dawley; Saponins; Signal Transduction; Transcription, Genetic; Triterpenes | 2020 |
Astragaloside IV alleviates lipopolysaccharide-induced preeclampsia-like phenotypes via suppressing the inflammatory responses.
Topics: Animals; Blood Pressure; Cytokines; Disease Models, Animal; Female; Heart Rate; Inflammation; Lipopolysaccharides; NF-kappa B; Phenotype; Placenta; Placenta Growth Factor; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; Proteinuria; Rats, Sprague-Dawley; RNA, Messenger; Saponins; Toll-Like Receptor 4; Triterpenes; Urine; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1 | 2021 |
Astragaloside IV attenuates inflammatory response mediated by NLRP-3/calpain-1 is involved in the development of pulmonary hypertension.
Topics: Animals; Blotting, Western; Calpain; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Humans; Immunohistochemistry; Inflammation; Interleukin-18; Male; NLR Family, Pyrin Domain-Containing 3 Protein; Rats, Sprague-Dawley; Saponins; Triterpenes | 2021 |
Astragaloside IV blocks monocrotaline‑induced pulmonary arterial hypertension by improving inflammation and pulmonary artery remodeling.
Topics: Animals; Hypertension, Pulmonary; Inflammation; Male; Monocrotaline; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Saponins; Triterpenes; Vascular Remodeling | 2021 |
Network Pharmacology and Experimental Evidence Identify the Mechanism of Astragaloside IV in Oxaliplatin Neurotoxicity.
Topics: Animals; Hyperalgesia; Inflammation; Injections, Intraperitoneal; Male; Neurotoxicity Syndromes; Oxaliplatin; Oxidative Stress; Rats; Rats, Sprague-Dawley; Saponins; Triterpenes | 2021 |
Induction of autophagy via the TLR4/NF-κB signaling pathway by astragaloside Ⅳ contributes to the amelioration of inflammation in RAW264.7 cells.
Topics: Animals; Anti-Inflammatory Agents; Autophagy; Cytokines; Inflammation; Macrophages; Mice; NF-kappa B; Phosphorylation; RAW 264.7 Cells; Saponins; Signal Transduction; Toll-Like Receptor 4; Triterpenes | 2021 |
Astragaloside alleviates alcoholic fatty liver disease by suppressing oxidative stress.
Topics: Animals; Apoptosis; Cell Line; Disease Models, Animal; Fatty Liver, Alcoholic; Inflammation; Lipid Metabolism; Liver Function Tests; Male; NF-kappa B; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Saponins; Signal Transduction; Triterpenes | 2021 |
Astragaloside-IV Alleviates Heat-Induced Inflammation by Inhibiting Endoplasmic Reticulum Stress and Autophagy.
Topics: Animals; Apoptosis; Autophagy; eIF-2 Kinase; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Eukaryotic Initiation Factor-2; Hot Temperature; Inflammation; Rats; Rats, Wistar; Reactive Oxygen Species; Saponins; Signal Transduction; Triterpenes | 2017 |
NRF2/HO-1 activation via ERK pathway involved in the anti-neuroinflammatory effect of Astragaloside IV in LPS induced microglial cells.
Topics: Animals; Anti-Inflammatory Agents; Cell Survival; Heme Oxygenase-1; Inflammation; Lipopolysaccharides; MAP Kinase Signaling System; Membrane Proteins; Mice; Microglia; NF-E2-Related Factor 2; Saponins; Triterpenes | 2018 |
Astragaloside IV Prevents Obesity-Associated Hypertension by Improving Pro-Inflammatory Reaction and Leptin Resistance.
Topics: Animals; Hypertension; Inflammation; Leptin; Male; Obesity; Rats; Rats, Wistar; Saponins; Triterpenes | 2018 |
Astragaloside IV protects against the pathological cardiac hypertrophy in mice.
Topics: Angiotensin II; Animals; Apoptosis; Cardiomegaly; Cardiotonic Agents; Enzyme Activation; Inflammation; Intracellular Signaling Peptides and Proteins; Male; Mice, Inbred C57BL; Myocardium; Myocytes, Cardiac; Phosphorylation; Pressure; Protein Serine-Threonine Kinases; Saponins; Signal Transduction; Triterpenes | 2018 |
Astragaloside IV ameliorates neuroinflammation-induced depressive-like behaviors in mice via the PPARγ/NF-κB/NLRP3 inflammasome axis.
Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents; Depressive Disorder, Major; Hippocampus; Inflammasomes; Inflammation; Male; Mice, Inbred ICR; Saponins; Signal Transduction; Triterpenes | 2018 |
Effect of Combined Use of Astragaloside IV (AsIV) and Atorvastatin (AV) on Expression of PPAR-γ and Inflammation-Associated Cytokines in Atherosclerosis Rats.
Topics: Animals; Atherosclerosis; Atorvastatin; China; Cytokines; Disease Models, Animal; Drug Therapy, Combination; Inflammation; Interleukin-18; Interleukin-6; Lipoproteins, HDL; Lipoproteins, LDL; Male; PPAR gamma; Rats; Rats, Sprague-Dawley; Saponins; Signal Transduction; Triterpenes; Tumor Necrosis Factor-alpha | 2018 |
Astragaloside IV prevents high glucose‑induced cell apoptosis and inflammatory reactions through inhibition of the JNK pathway in human umbilical vein endothelial cells.
Topics: Apoptosis; Astragalus propinquus; Cell Proliferation; Glucose; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; MAP Kinase Signaling System; Saponins; Signal Transduction; Triterpenes | 2019 |
Astragaloside IV Regulates the PI3K/Akt/HO-1 Signaling Pathway and Inhibits H9c2 Cardiomyocyte Injury Induced by Hypoxia-Reoxygenation.
Topics: Animals; Basic-Leucine Zipper Transcription Factors; Cell Hypoxia; Cell Survival; Cells, Cultured; Heme Oxygenase-1; Inflammation; Myocardial Reperfusion Injury; Myocytes, Cardiac; NF-E2-Related Factor 2; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Repressor Proteins; Saponins; Signal Transduction; Triterpenes | 2019 |
Astragaloside IV Protects Against Oxidized Low-Density Lipoprotein (ox-LDL)-Induced Endothelial Cell Injury by Reducing Oxidative Stress and Inflammation.
Topics: Antioxidants; Apoptosis; Cell Movement; Cell Survival; Endothelial Cells; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; L-Lactate Dehydrogenase; Lipoproteins, LDL; NADP; NADPH Oxidases; Oxidative Stress; Protective Agents; Reactive Oxygen Species; Saponins; Triterpenes; Tumor Necrosis Factor-alpha | 2019 |
Astragaloside IV ameliorates renal injury in streptozotocin-induced diabetic rats through inhibiting NF-κB-mediated inflammatory genes expression.
Topics: Albuminuria; Animals; Biomarkers; Chemokine CCL2; Collagen Type IV; Diabetes Mellitus, Experimental; Gene Expression Regulation; Inflammation; Intercellular Adhesion Molecule-1; Kidney Diseases; Male; NF-kappa B; Podocytes; Rats; Rats, Sprague-Dawley; RNA, Messenger; Saponins; Triterpenes; Tumor Necrosis Factor-alpha | 2013 |
Astragaloside IV attenuates experimental autoimmune encephalomyelitis of mice by counteracting oxidative stress at multiple levels.
Topics: Animals; Antioxidants; Apoptosis Regulatory Proteins; CD11b Antigen; Cell Line; Cytokines; Demyelinating Diseases; Disease Models, Animal; Disease Progression; Drugs, Chinese Herbal; Encephalomyelitis, Autoimmune, Experimental; Female; Forkhead Transcription Factors; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Humans; Inflammation; Mice; Multiple Sclerosis; Nerve Tissue Proteins; Nitric Oxide Synthase Type II; Nuclear Receptor Subfamily 1, Group F, Member 3; Oxidative Stress; Reactive Oxygen Species; RNA, Messenger; Saponins; T-Box Domain Proteins; Th1 Cells; Th17 Cells; Triterpenes | 2013 |
Astragaloside IV attenuates allergic inflammation by regulation Th1/Th2 cytokine and enhancement CD4(+)CD25(+)Foxp3 T cells in ovalbumin-induced asthma.
Topics: Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cytokines; Drugs, Chinese Herbal; Eosinophilia; Female; Flow Cytometry; Forkhead Transcription Factors; Inflammation; Interferon-gamma; Interleukin-10; Interleukin-2 Receptor alpha Subunit; Interleukin-4; Lung; Mice, Inbred BALB C; Ovalbumin; Reverse Transcriptase Polymerase Chain Reaction; Saponins; T-Lymphocytes, Regulatory; Th1 Cells; Th2 Cells; Triterpenes | 2014 |
Astragaloside IV inhibits NF- κ B activation and inflammatory gene expression in LPS-treated mice.
Topics: Animals; Astragalus propinquus; Chemokine CCL2; Female; Inflammation; Interleukin-6; Lipopolysaccharides; Lung; Mice; Mice, Inbred C57BL; Myocardium; NF-kappa B; Peroxidase; Saponins; Signal Transduction; Tissue Distribution; Toll-Like Receptor 4; Transcription Factor AP-1; Triterpenes; Tumor Necrosis Factor-alpha | 2015 |
Protective effect of astragaloside IV on lipopolysaccharide-induced cardiac dysfunction via downregulation of inflammatory signaling in mice.
Topics: Animals; Cytokines; Heart Diseases; Inflammation; Lipopolysaccharides; Mice; Myocardium; Oncogene Protein v-akt; Saponins; Signal Transduction; Transcription Factor RelA; Triterpenes | 2015 |
Effects of the Combination of the Main Active Components of Astragalus and Panax notoginseng on Inflammation and Apoptosis of Nerve Cell after Cerebral Ischemia-Reperfusion.
Topics: Animals; Apoptosis; Astragalus Plant; Brain Ischemia; CA1 Region, Hippocampal; Cell Survival; Disease Models, Animal; Drug Combinations; Endoplasmic Reticulum Chaperone BiP; Ginsenosides; Inflammation; Janus Kinase 1; Male; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; NF-kappa B; Panax notoginseng; Phytotherapy; Reperfusion Injury; Saponins; STAT1 Transcription Factor; Triterpenes | 2015 |
Astragaloside IV Inhibits the Inflammatory Injury of Chicken Type II Pneumocytes Induced by Avian Pathogenic Escherichia coli.
Topics: Actins; Alveolar Epithelial Cells; Animals; Bacterial Adhesion; Chickens; Cytokines; Escherichia coli; Escherichia coli Infections; Gene Expression Regulation; Inflammation; Inflammation Mediators; Saponins; Triterpenes | 2016 |
Inhibitory Effects of Astragaloside IV on Bleomycin-Induced Pulmonary Fibrosis in Rats Via Attenuation of Oxidative Stress and Inflammation.
Topics: Animals; Bleomycin; Dose-Response Relationship, Drug; Inflammation; Oxidative Stress; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Saponins; Triterpenes | 2016 |
Astragaloside IV from Astragalus membranaceus ameliorates renal interstitial fibrosis by inhibiting inflammation via TLR4/NF-кB in vivo and in vitro.
Topics: Animals; Anti-Inflammatory Agents; Astragalus propinquus; Cell Line; Fibrosis; Humans; Inflammation; Kidney; Kidney Diseases; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred C57BL; NF-kappa B; Saponins; Signal Transduction; Toll-Like Receptor 4; Triterpenes; Ureteral Obstruction | 2017 |
Astragaloside IV ameliorates allergic inflammation by inhibiting key initiating factors in the initial stage of sensitization.
Topics: Animals; Cytokines; Humans; Hypersensitivity; Inflammation; Interleukin-33; Mice; Mice, Inbred BALB C; Saponins; Th2 Cells; Thymic Stromal Lymphopoietin; Triterpenes | 2016 |
Astragaloside IV attenuates cognitive impairments induced by transient cerebral ischemia and reperfusion in mice via anti-inflammatory mechanisms.
Topics: Animals; Anti-Inflammatory Agents; Cognitive Dysfunction; Disease Models, Animal; Inflammation; Ischemic Attack, Transient; Male; Mice; Neuroprotective Agents; NF-kappa B; Reperfusion; Saponins; Toll-Like Receptor 4; Triterpenes | 2017 |
Effects of astragaloside IV on IFN-gamma level and prolonged airway dysfunction in a murine model of chronic asthma.
Topics: Animals; Asthma; Astragalus Plant; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Chronic Disease; Collagen; Disease Models, Animal; Drugs, Chinese Herbal; Female; Immune System; Inflammation; Interferon-gamma; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Phytotherapy; Plant Roots; Respiratory System; Saponins; Triterpenes | 2011 |