astragaloside a has been researched along with Injury, Ischemia-Reperfusion in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (8.82) | 29.6817 |
| 2010's | 18 (52.94) | 24.3611 |
| 2020's | 13 (38.24) | 2.80 |
| Authors | Studies |
|---|---|
| Deng, CQ; Ding, H; Huang, XP; Liu, XD; Tang, S; Yang, XQ; Zeng, XB; Zhu, QY | 1 |
| Du, Y; He, Y; Li, C; Wan, H; Xu, S; Yang, J | 1 |
| Han, X; Shu, Z; Tang, J; Wang, Y; Yu, L | 1 |
| He, Y; Huang, B; Huang, J; Meng, Y; Shen, F; Wang, L | 1 |
| Liu, C; Tang, B; Wang, L | 1 |
| Kang, Z; Tang, B; Wang, L; Xiao, L; Xiao, Q | 1 |
| Deng, CQ; Ding, H; Huang, MT; Huang, XP; Li, Y; Li, YL; Liu, CX; Liu, XD; Tang, S; Xiong, HL; Zhang, W | 1 |
| Chen, J; Chen, L; Han, Y; Hu, X; Miao, H; Ou, Z; Wang, Y; Yao, J | 1 |
| Fang, Y; He, Y; Li, C; Wan, H; Yang, J; Yin, F; Yu, L; Zhou, H | 1 |
| Huang, H; Liu, W; Xu, Z | 1 |
| Dong, YJ; Du, SJ; Gao, WJ; Tang, JL; Zhang, Y; Zhao, YM; Zhou, XH | 1 |
| Chu, L; Fang, Y; Gan, H; Hu, X; Jin, H; Li, L; Yang, Y; Zhang, J | 1 |
| He, Y; Li, W; Shao, C; Wan, H; Yang, J | 1 |
| Deng, CQ; Huang, XP; Li, JX; Liu, XD; Tang, B; Tang, YH; Yang, XQ | 1 |
| Hu, N; Hu, X; Hu, Y; Qiu, Y; Song, Z; Zhou, L | 1 |
| Deng, CQ; Tang, B; Tang, WJ; Tang, YH | 1 |
| Gao, GD; Li, LH; Li, M; Ma, RN; Qu, YZ | 1 |
| Guo, Y; Liu, G; Song, J; Wang, T; Zhou, Z | 1 |
| Chang, CP; Chiu, BY; Hsu, YC; Lin, JW; Lin, MT; Liu, WP; Yu, JS | 1 |
| Chen, GQ; Gu, DM; Lu, PH; Sun, M; Wang, Q; Wang, X; Zhang, K | 1 |
| Cao, YL; Chen, CF; Cheng, HX; Feng, YB; Wang, AW; Xin, W; Zhang, WW | 1 |
| Deng, BX; Deng, CQ; Ding, H; Huang, XP; Lu, JD; Tang, YH | 1 |
| Gao, GD; Gao, L; Li, M; Liu, JP; Qu, YZ; Wei, XY; Zhao, YL; Zhao, ZW | 1 |
| Gong, HL; Li, WP; Li, WZ; Wu, GC; Yin, YY; Zhu, FF | 1 |
| Jiang, LZ; Liao, XQ; Xiong, P | 1 |
| Wu, GC; Yin, YY; Zhu, FF | 1 |
| Li, JH; Wan, HT; Zhu, ZH | 1 |
| Cai, YL; Chen, ZZ; Cheng, MX; Liu, CA; Tu, B | 1 |
| Li, J; Lu, J; Wan, H; Yang, J; Zhang, Y; Zhu, Z | 1 |
| Gao, GD; Gao, L; Li, M; Liu, YY; Qu, YZ; Wei, XY; Wu, SX; Zhao, ZW | 1 |
| Bian, ZP; Chen, XJ; Gu, CR; Wu, HF; Xu, JD; Yang, D; Zhang, DW; Zhou, B | 1 |
| Gui, D; Guo, Y; Huang, J; Liu, W; Wang, N; Xiao, W | 1 |
| Chen, J; Ding, D; Fu, JH; Hong, Z; Luo, Y; Qin, Z; Zhang, WD; Zhang, X | 1 |
| Yu, QC; Zhang, YK; Zhu, TY | 1 |
34 other study(ies) available for astragaloside a and Injury, Ischemia-Reperfusion
| Article | Year |
|---|---|
Borneol enhances the protective effect against cerebral ischemia/reperfusion injury by promoting the access of astragaloside IV and the components of Panax notoginseng saponins into the brain.
Topics: Animals; Brain; Brain Ischemia; Camphanes; Panax notoginseng; Rats; Reperfusion Injury; Saponins; Triterpenes | 2022 |
LC-MS/MS combined with blood-brain dual channel microdialysis for simultaneous determination of active components of astragali radix-safflower combination and neurotransmitters in rats with cerebral ischemia reperfusion injury: Application in pharmacokine
Topics: Animals; Aspartic Acid; Astragalus Plant; Blood-Brain Barrier; Carthamus tinctorius; Chalcone; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dopamine; Drugs, Chinese Herbal; gamma-Aminobutyric Acid; Glucosides; Glutamates; Microdialysis; Neurotransmitter Agents; Phenylpropionates; Quinones; Rats; Reperfusion Injury; Saponins; Serotonin; Tandem Mass Spectrometry; Triterpenes | 2022 |
Astragaloside IV ameliorates cerebral ischemia-reperfusion injury via upregulation of PKA and Cx36.
Topics: Animals; bcl-2-Associated X Protein; Brain Ischemia; Cerebral Infarction; Isoquinolines; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Saponins; Sulfonamides; Triterpenes; Up-Regulation | 2022 |
Antihypertension effect of astragaloside IV during cerebral ischemia reperfusion in rats.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Infarction, Middle Cerebral Artery; Rats; Rats, Sprague-Dawley; Reperfusion; Reperfusion Injury; Saponins; Triterpenes | 2023 |
Astragaloside IV mitigates cerebral ischaemia-reperfusion injury via inhibition of P62/Keap1/Nrf2 pathway-mediated ferroptosis.
Topics: Animals; Brain Ischemia; Ferroptosis; Humans; Kelch-Like ECH-Associated Protein 1; Neuroblastoma; NF-E2-Related Factor 2; Oxygen; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; Stroke | 2023 |
The combination of astragaloside IV and Panax notoginseng saponins attenuates cerebral ischaemia-reperfusion injury in rats through ferroptosis and inflammation inhibition via activating Nrf2.
Topics: Animals; Ferroptosis; Inflammation; NF-E2-Related Factor 2; Panax notoginseng; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Saponins | 2023 |
Effects of borneol combined with astragaloside IV and Panax notoginseng saponins regulation of microglia polarization to promote neurogenesis after cerebral ischaemia.
Topics: Animals; Brain Ischemia; Microglia; Myeloid Differentiation Factor 88; Neurogenesis; NF-kappa B; Panax notoginseng; Rats; Reperfusion Injury; Saponins; Toll-Like Receptor 4 | 2023 |
Astragaloside IV promotes angiogenesis by targeting SIRT7/VEGFA signaling pathway to improve brain injury after cerebral infarction in rats.
Topics: Animals; Brain Injuries; Brain Ischemia; Infarction, Middle Cerebral Artery; Molecular Docking Simulation; Oxygen; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; Sirtuins | 2023 |
Astragaloside IV alleviates ischemia reperfusion-induced apoptosis by inhibiting the activation of key factors in death receptor pathway and mitochondrial pathway.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Brain; Brain Infarction; Disease Models, Animal; Male; Mitochondria; Neuroprotective Agents; Rats, Sprague-Dawley; Receptors, Death Domain; Reperfusion Injury; Saponins; Signal Transduction; Triterpenes | 2020 |
Astragaloside IV Alleviates Cerebral Ischemia-Reperfusion Injury by Activating the Janus Kinase 2 and Signal Transducer and Activator of Transcription 3 Signaling Pathway.
Topics: Animals; Apoptosis; Brain Ischemia; Disease Models, Animal; Janus Kinase 2; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Saponins; Signal Transduction; STAT3 Transcription Factor; Superoxide Dismutase; Triterpenes | 2020 |
Astragaloside IV attenuates cerebral ischemia‑reperfusion injury in rats through the inhibition of calcium‑sensing receptor‑mediated apoptosis.
Topics: Animals; Apoptosis; Cerebrovascular Disorders; Disease Models, Animal; Male; Rats; Rats, Sprague-Dawley; Receptors, Calcium-Sensing; Reperfusion Injury; Saponins; Triterpenes | 2021 |
Astragaloside IV promotes microglia/macrophages M2 polarization and enhances neurogenesis and angiogenesis through PPARγ pathway after cerebral ischemia/reperfusion injury in rats.
Topics: Animals; Brain Injuries; Cell Polarity; Disease Models, Animal; Infarction, Middle Cerebral Artery; Macrophages; Male; Microglia; Neovascularization, Physiologic; Neurogenesis; PPAR gamma; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Saponins; Triterpenes | 2021 |
Protective effects of Astragaloside IV against oxidative injury and apoptosis in cultured astrocytes by regulating Nrf2/JNK signaling.
Topics: Animals; Apoptosis; Astrocytes; Cells, Cultured; Kelch-Like ECH-Associated Protein 1; MAP Kinase Signaling System; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Oxygen; Rats; Reperfusion Injury; Saponins; Triterpenes | 2021 |
[Effect of astragaloside Ⅳ combined with Panax notoginseng saponins on cerebral ischemia-reperfusion injury and study of pharmacokinetics in rats].
Topics: Animals; Chromatography, Liquid; Ginsenosides; Panax notoginseng; Plants, Medicinal; Rats; Reperfusion Injury; Saponins; Tandem Mass Spectrometry; Triterpenes | 2017 |
Protective role of astragalus injection in spinal cord ischemia-reperfusion injury in rats.
Topics: Animals; Aquaporin 4; Astragalus Plant; Neuroprotective Agents; Phosphopyruvate Hydratase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Saponins; Spinal Cord; Spinal Cord Injuries; Triterpenes | 2018 |
[Astragaloside IV attenuates cerebral ischemia and reperfusion injury and reduces activation of NLRP3 inflammasome and NF-κB phosphorylation in rats following a transient middle cerebral artery occlusion].
Topics: Animals; Brain Ischemia; Infarction, Middle Cerebral Artery; Inflammasomes; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Phosphorylation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Saponins; Triterpenes | 2019 |
Astragaloside IV reduces cerebral edema post-ischemia/reperfusion correlating the suppression of MMP-9 and AQP4.
Topics: Animals; Aquaporin 4; Blood Vessels; Blood-Brain Barrier; Brain Edema; Male; Matrix Metalloproteinase 9; Permeability; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Saponins; Treatment Outcome; Triterpenes; Water | 2013 |
Astragalus injection protects cerebral ischemic injury by inhibiting neuronal apoptosis and the expression of JNK3 after cerebral ischemia reperfusion in rats.
Topics: Animals; Apoptosis; Brain Ischemia; Disease Models, Animal; Down-Regulation; Drugs, Chinese Herbal; Male; Mitogen-Activated Protein Kinase 10; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Reperfusion Injury; Saponins; Triterpenes | 2013 |
Beneficial effect of astragalosides on stroke condition using PC12 cells under oxygen glucose deprivation and reperfusion.
Topics: Animals; Cell Death; Cell Line; Cell Survival; Glucose; Mitochondria; Neuroprotective Agents; Oxygen; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Rats; Reperfusion Injury; Saponins; Stroke; Triterpenes | 2014 |
EGFR mediates astragaloside IV-induced Nrf2 activation to protect cortical neurons against in vitro ischemia/reperfusion damages.
Topics: Animals; Antioxidants; Cerebral Cortex; Disease Models, Animal; Drugs, Chinese Herbal; ErbB Receptors; Gene Knockdown Techniques; Mice; Neurons; Neuroprotective Agents; NF-E2-Related Factor 2; Primary Cell Culture; Reactive Oxygen Species; Reperfusion Injury; RNA, Messenger; Saponins; Transcriptional Activation; Triterpenes | 2015 |
Changes of peripheral-type benzodiazepine receptors in the penumbra area after cerebral ischemia-reperfusion injury and effects of astragaloside IV on rats.
Topics: Animals; Brain; Brain Ischemia; Female; Isoquinolines; Male; Mitochondria; Rats, Sprague-Dawley; Receptors, GABA-A; Reperfusion Injury; Saponins; Triterpenes; Tritium | 2015 |
Effects of the Combination of the Main Active Components of Astragalus and Panax notoginseng on Inflammation and Apoptosis of Nerve Cell after Cerebral Ischemia-Reperfusion.
Topics: Animals; Apoptosis; Astragalus Plant; Brain Ischemia; CA1 Region, Hippocampal; Cell Survival; Disease Models, Animal; Drug Combinations; Endoplasmic Reticulum Chaperone BiP; Ginsenosides; Inflammation; Janus Kinase 1; Male; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; NF-kappa B; Panax notoginseng; Phytotherapy; Reperfusion Injury; Saponins; STAT1 Transcription Factor; Triterpenes | 2015 |
Astragaloside IV attenuates cerebral ischemia-reperfusion-induced increase in permeability of the blood-brain barrier in rats.
Topics: Animals; Blood-Brain Barrier; Brain Ischemia; Male; Membrane Proteins; Microscopy, Electron; Occludin; Permeability; Phosphoproteins; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Saponins; Tight Junctions; Triterpenes; Zonula Occludens-1 Protein | 2009 |
Protective effect of astragaloside on focal cerebral ischemia/reperfusion injury in rats.
Topics: Animals; Brain; Brain Ischemia; Cerebral Infarction; Drugs, Chinese Herbal; Infarction, Middle Cerebral Artery; L-Lactate Dehydrogenase; Lactates; Male; Malondialdehyde; Nerve Growth Factor; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Receptor, trkA; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; Saponins; Superoxide Dismutase; Time Factors; Triterpenes; Water | 2010 |
[Morphological investigation of the protective effect of astragaloside preconditioning against ischemia-reperfusion lung injury in rats].
Topics: Animals; Female; Ischemic Preconditioning; Lung; Male; Phytotherapy; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Saponins; Triterpenes | 2010 |
[Protective effect of astragalosides on anoxia/reoxygenation injury of hippocampal neuron].
Topics: Animals; Calcium; Cell Hypoxia; Female; Fetus; Hippocampus; Malondialdehyde; Neurons; Neuroprotective Agents; Nitric Oxide; Pregnancy; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Saponins; Superoxide Dismutase; Triterpenes | 2010 |
Chuanxiongzine-astragaloside IV decreases IL-1β and Caspase-3 gene expressions in rat brain damaged by cerebral ischemia/reperfusion: a study of real-time quantitative PCR assay.
Topics: Animals; Brain; Brain Ischemia; Caspase 3; Interleukin-1beta; Male; Neuroprotective Agents; Pyrazines; Random Allocation; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reperfusion Injury; RNA, Messenger; Saponins; Triterpenes | 2011 |
Astragaloside IV protects against ischemia reperfusion in a murine model of orthotopic liver transplantation.
Topics: Animals; Base Sequence; Blotting, Western; DNA Primers; Immunohistochemistry; Liver Transplantation; Male; Mice; Microscopy, Confocal; NF-kappa B; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Reperfusion Injury; Saponins; Survival Rate; Triterpenes; Tumor Necrosis Factor-alpha | 2011 |
Synergistic protective effect of astragaloside IV-tetramethylpyrazine against cerebral ischemic-reperfusion injury induced by transient focal ischemia.
Topics: Animals; Astragalus Plant; Cardiovascular Agents; Caspase 3; Disease Models, Animal; Drug Synergism; Glucose; Hippocampus; Ischemic Attack, Transient; Male; Malondialdehyde; Neuroprotective Agents; Nimodipine; Nitric Oxide Synthase Type II; Phytotherapy; Plant Extracts; Positron-Emission Tomography; Proto-Oncogene Proteins c-bcl-2; Pyrazines; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Messenger; Saponins; Superoxide Dismutase; Triterpenes | 2012 |
Astragaloside IV protects against focal cerebral ischemia/reperfusion injury correlating to suppression of neutrophils adhesion-related molecules.
Topics: Animals; Blotting, Western; Brain Ischemia; Cell Adhesion; Cell Adhesion Molecules; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Immunohistochemistry; Interleukin-1beta; Male; Neutrophils; NF-kappa B; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Saponins; Triterpenes; Tumor Necrosis Factor-alpha | 2012 |
Astragaloside IV alleviates hypoxia/reoxygenation-induced neonatal rat cardiomyocyte injury via the protein kinase a pathway.
Topics: Animals; Animals, Newborn; Cardiotonic Agents; Cell Hypoxia; Cells, Cultured; Creatine Kinase, MB Form; Cyclic AMP-Dependent Protein Kinases; Gene Expression; Myocytes, Cardiac; Protein Subunits; Rats; Reperfusion Injury; RNA, Messenger; Saponins; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Triterpenes | 2012 |
Astragaloside IV prevents acute kidney injury in two rodent models by inhibiting oxidative stress and apoptosis pathways.
Topics: Acute Kidney Injury; Acute-Phase Proteins; Animals; Apoptosis; Caspase 3; Cell Adhesion Molecules; Cystatin C; Drugs, Chinese Herbal; Ischemia; Kidney; Kidney Function Tests; Lipocalin-2; Lipocalins; Male; Models, Animal; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Renal Artery; Reperfusion Injury; RNA, Messenger; Saponins; Triterpenes | 2013 |
Astragaloside IV protects against ischemic brain injury in a murine model of transient focal ischemia.
Topics: Animals; Brain Chemistry; Brain Ischemia; Cardiotonic Agents; Catalase; Cerebral Infarction; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Glutathione Peroxidase; Infarction, Middle Cerebral Artery; Lipid Peroxidation; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Reperfusion Injury; Saponins; Superoxide Dismutase; Triterpenes | 2004 |
[Effect of astrgaloside IV on the long-term consequences of renal ischemia-reperfusion injury in rat].
Topics: Animals; Down-Regulation; Drugs, Chinese Herbal; Kidney; Male; Nephrectomy; Phytotherapy; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Messenger; Saponins; Transforming Growth Factor beta; Triterpenes | 2004 |