Page last updated: 2024-09-03

astragaloside a and Cerebral Ischemia

astragaloside a has been researched along with Cerebral Ischemia in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (9.52)29.6817
2010's11 (52.38)24.3611
2020's8 (38.10)2.80

Authors

AuthorsStudies
Deng, CQ; Ding, H; Huang, XP; Liu, XD; Tang, S; Yang, XQ; Zeng, XB; Zhu, QY1
Han, X; Shu, Z; Tang, J; Wang, Y; Yu, L1
He, Y; Huang, B; Huang, J; Meng, Y; Shen, F; Wang, L1
Liu, C; Tang, B; Wang, L1
Ding, Z; He, Y; Lin, B; Wan, H; Wei, X; Yang, J; Yin, J; Zhou, H1
Deng, CQ; Ding, H; Huang, MT; Huang, XP; Li, Y; Li, YL; Liu, CX; Liu, XD; Tang, S; Xiong, HL; Zhang, W1
Chen, J; Chen, L; Han, Y; Hu, X; Miao, H; Ou, Z; Wang, Y; Yao, J1
Huang, H; Liu, W; Xu, Z1
Chu, H; Dong, J; Dong, Q; Gao, Z; Huang, C; Tang, Y1
Cai, SQ; Wang, D; Xu, F; Ye, J; Zhang, WW1
Alves, RD; Cavalcante, JS; Cavalcanti, JRLP; Costa, IM; Fernandes, LCB; Filho, IA; Freire, MAM; Guzen, FP; Lima, FOV; Lucena, EES; Neta, FI; Norrara, B; Queiroz, DB; Rego, ACM1
Deng, CQ; Tang, B; Tang, WJ; Tang, YH1
Guo, Y; Liu, G; Song, J; Wang, T; Zhou, Z1
Cao, YL; Chen, CF; Cheng, HX; Feng, YB; Wang, AW; Xin, W; Zhang, WW1
Deng, BX; Deng, CQ; Ding, H; Huang, XP; Lu, JD; Tang, YH1
Wang, HL; Xu, MB; Zheng, GQ; Zhou, QH; Zhou, XL1
Gao, GD; Gao, L; Li, M; Liu, JP; Qu, YZ; Wei, XY; Zhao, YL; Zhao, ZW1
Gong, HL; Li, WP; Li, WZ; Wu, GC; Yin, YY; Zhu, FF1
Li, JH; Wan, HT; Zhu, ZH1
Gao, GD; Gao, L; Li, M; Liu, YY; Qu, YZ; Wei, XY; Wu, SX; Zhao, ZW1
Chen, J; Ding, D; Fu, JH; Hong, Z; Luo, Y; Qin, Z; Zhang, WD; Zhang, X1

Reviews

2 review(s) available for astragaloside a and Cerebral Ischemia

ArticleYear
Astragaloside IV Supplementation Promotes A Neuroprotective Effect in Experimental Models of Neurological Disorders: A Systematic Review.
    Current neuropharmacology, 2019, Volume: 17, Issue:7

    Topics: Alzheimer Disease; Animals; Brain Ischemia; Encephalomyelitis; Humans; Nervous System Diseases; Neuroprotective Agents; Parkinson Disease; Saponins; Triterpenes

2019
Astragaloside IV for Experimental Focal Cerebral Ischemia: Preclinical Evidence and Possible Mechanisms.
    Oxidative medicine and cellular longevity, 2017, Volume: 2017

    Topics: Amino Acid Sequence; Animals; Brain Ischemia; Drug Evaluation, Preclinical; Models, Molecular; Publication Bias; Saponins; Stroke; Treatment Outcome; Triterpenes

2017

Other Studies

19 other study(ies) available for astragaloside a and Cerebral Ischemia

ArticleYear
Borneol enhances the protective effect against cerebral ischemia/reperfusion injury by promoting the access of astragaloside IV and the components of Panax notoginseng saponins into the brain.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2022, Volume: 94

    Topics: Animals; Brain; Brain Ischemia; Camphanes; Panax notoginseng; Rats; Reperfusion Injury; Saponins; Triterpenes

2022
Astragaloside IV ameliorates cerebral ischemia-reperfusion injury via upregulation of PKA and Cx36.
    Neuroreport, 2022, 10-12, Volume: 33, Issue:15

    Topics: Animals; bcl-2-Associated X Protein; Brain Ischemia; Cerebral Infarction; Isoquinolines; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Saponins; Sulfonamides; Triterpenes; Up-Regulation

2022
Antihypertension effect of astragaloside IV during cerebral ischemia reperfusion in rats.
    Molecular medicine reports, 2023, Volume: 27, Issue:1

    Topics: Animals; Brain Ischemia; Disease Models, Animal; Infarction, Middle Cerebral Artery; Rats; Rats, Sprague-Dawley; Reperfusion; Reperfusion Injury; Saponins; Triterpenes

2023
Astragaloside IV mitigates cerebral ischaemia-reperfusion injury via inhibition of P62/Keap1/Nrf2 pathway-mediated ferroptosis.
    European journal of pharmacology, 2023, Apr-05, Volume: 944

    Topics: Animals; Brain Ischemia; Ferroptosis; Humans; Kelch-Like ECH-Associated Protein 1; Neuroblastoma; NF-E2-Related Factor 2; Oxygen; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; Stroke

2023
Integrated transcriptomics, proteomics and metabolomics to identify biomarkers of astragaloside IV against cerebral ischemic injury in rats.
    Food & function, 2023, Apr-24, Volume: 14, Issue:8

    Topics: Animals; Biomarkers; Brain Injuries; Brain Ischemia; Drugs, Chinese Herbal; Infarction, Middle Cerebral Artery; Metabolomics; Proteomics; Rats; Rats, Sprague-Dawley; Transcriptome

2023
Effects of borneol combined with astragaloside IV and Panax notoginseng saponins regulation of microglia polarization to promote neurogenesis after cerebral ischaemia.
    The Journal of pharmacy and pharmacology, 2023, Jul-05, Volume: 75, Issue:7

    Topics: Animals; Brain Ischemia; Microglia; Myeloid Differentiation Factor 88; Neurogenesis; NF-kappa B; Panax notoginseng; Rats; Reperfusion Injury; Saponins; Toll-Like Receptor 4

2023
Astragaloside IV promotes angiogenesis by targeting SIRT7/VEGFA signaling pathway to improve brain injury after cerebral infarction in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 168

    Topics: Animals; Brain Injuries; Brain Ischemia; Infarction, Middle Cerebral Artery; Molecular Docking Simulation; Oxygen; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; Sirtuins

2023
Astragaloside IV Alleviates Cerebral Ischemia-Reperfusion Injury by Activating the Janus Kinase 2 and Signal Transducer and Activator of Transcription 3 Signaling Pathway.
    Pharmacology, 2020, Volume: 105, Issue:3-4

    Topics: Animals; Apoptosis; Brain Ischemia; Disease Models, Animal; Janus Kinase 2; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Saponins; Signal Transduction; STAT3 Transcription Factor; Superoxide Dismutase; Triterpenes

2020
Reduction of Ischemic Brain Edema by Combined use of Paeoniflorin and Astragaloside IV via Down-Regulating Connexin 43.
    Phytotherapy research : PTR, 2017, Volume: 31, Issue:9

    Topics: Animals; Aquaporin 4; Brain Edema; Brain Ischemia; Connexin 43; Down-Regulation; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Glucosides; JNK Mitogen-Activated Protein Kinases; Male; Monoterpenes; Rats, Sprague-Dawley; Saponins; Signal Transduction; Triterpenes

2017
Buyang Huanwu Decoction ameliorates ischemic stroke by modulating multiple targets with multiple components: In vitro evidences.
    Chinese journal of natural medicines, 2018, Volume: 16, Issue:3

    Topics: Animals; Apoptosis; Brain Ischemia; Drugs, Chinese Herbal; Glucosides; Isoflavones; Male; Mice; Mice, Inbred BALB C; Monoterpenes; PC12 Cells; Rats; Rats, Sprague-Dawley; RAW 264.7 Cells; Saponins; Stroke; Triterpenes

2018
[Astragaloside IV attenuates cerebral ischemia and reperfusion injury and reduces activation of NLRP3 inflammasome and NF-κB phosphorylation in rats following a transient middle cerebral artery occlusion].
    Sheng li xue bao : [Acta physiologica Sinica], 2019, Jun-25, Volume: 71, Issue:3

    Topics: Animals; Brain Ischemia; Infarction, Middle Cerebral Artery; Inflammasomes; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Phosphorylation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Saponins; Triterpenes

2019
Astragalus injection protects cerebral ischemic injury by inhibiting neuronal apoptosis and the expression of JNK3 after cerebral ischemia reperfusion in rats.
    Behavioral and brain functions : BBF, 2013, Oct-01, Volume: 9

    Topics: Animals; Apoptosis; Brain Ischemia; Disease Models, Animal; Down-Regulation; Drugs, Chinese Herbal; Male; Mitogen-Activated Protein Kinase 10; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Reperfusion Injury; Saponins; Triterpenes

2013
Changes of peripheral-type benzodiazepine receptors in the penumbra area after cerebral ischemia-reperfusion injury and effects of astragaloside IV on rats.
    Genetics and molecular research : GMR, 2015, Jan-23, Volume: 14, Issue:1

    Topics: Animals; Brain; Brain Ischemia; Female; Isoquinolines; Male; Mitochondria; Rats, Sprague-Dawley; Receptors, GABA-A; Reperfusion Injury; Saponins; Triterpenes; Tritium

2015
Effects of the Combination of the Main Active Components of Astragalus and Panax notoginseng on Inflammation and Apoptosis of Nerve Cell after Cerebral Ischemia-Reperfusion.
    The American journal of Chinese medicine, 2015, Volume: 43, Issue:7

    Topics: Animals; Apoptosis; Astragalus Plant; Brain Ischemia; CA1 Region, Hippocampal; Cell Survival; Disease Models, Animal; Drug Combinations; Endoplasmic Reticulum Chaperone BiP; Ginsenosides; Inflammation; Janus Kinase 1; Male; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; NF-kappa B; Panax notoginseng; Phytotherapy; Reperfusion Injury; Saponins; STAT1 Transcription Factor; Triterpenes

2015
Astragaloside IV attenuates cerebral ischemia-reperfusion-induced increase in permeability of the blood-brain barrier in rats.
    European journal of pharmacology, 2009, Mar-15, Volume: 606, Issue:1-3

    Topics: Animals; Blood-Brain Barrier; Brain Ischemia; Male; Membrane Proteins; Microscopy, Electron; Occludin; Permeability; Phosphoproteins; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Saponins; Tight Junctions; Triterpenes; Zonula Occludens-1 Protein

2009
Protective effect of astragaloside on focal cerebral ischemia/reperfusion injury in rats.
    The American journal of Chinese medicine, 2010, Volume: 38, Issue:3

    Topics: Animals; Brain; Brain Ischemia; Cerebral Infarction; Drugs, Chinese Herbal; Infarction, Middle Cerebral Artery; L-Lactate Dehydrogenase; Lactates; Male; Malondialdehyde; Nerve Growth Factor; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Receptor, trkA; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; Saponins; Superoxide Dismutase; Time Factors; Triterpenes; Water

2010
Chuanxiongzine-astragaloside IV decreases IL-1β and Caspase-3 gene expressions in rat brain damaged by cerebral ischemia/reperfusion: a study of real-time quantitative PCR assay.
    Sheng li xue bao : [Acta physiologica Sinica], 2011, Jun-25, Volume: 63, Issue:3

    Topics: Animals; Brain; Brain Ischemia; Caspase 3; Interleukin-1beta; Male; Neuroprotective Agents; Pyrazines; Random Allocation; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reperfusion Injury; RNA, Messenger; Saponins; Triterpenes

2011
Astragaloside IV protects against focal cerebral ischemia/reperfusion injury correlating to suppression of neutrophils adhesion-related molecules.
    Neurochemistry international, 2012, Volume: 60, Issue:5

    Topics: Animals; Blotting, Western; Brain Ischemia; Cell Adhesion; Cell Adhesion Molecules; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Immunohistochemistry; Interleukin-1beta; Male; Neutrophils; NF-kappa B; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Saponins; Triterpenes; Tumor Necrosis Factor-alpha

2012
Astragaloside IV protects against ischemic brain injury in a murine model of transient focal ischemia.
    Neuroscience letters, 2004, Jun-17, Volume: 363, Issue:3

    Topics: Animals; Brain Chemistry; Brain Ischemia; Cardiotonic Agents; Catalase; Cerebral Infarction; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Glutathione Peroxidase; Infarction, Middle Cerebral Artery; Lipid Peroxidation; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Reperfusion Injury; Saponins; Superoxide Dismutase; Triterpenes

2004