astragaloside a has been researched along with Cardiomegaly in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 9 (81.82) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Duan, DD; Jin, G; Liu, X; Luan, X; Sun, Q; Tian, S; Wan, J; Wang, P; Wu, C; Yang, Y; Ye, LL; Zang, Y; Zhan, X; Zhang, W; Zhang, Z | 1 |
| Bian, ZP; Chen, XJ; Ding, YZ; Gu, CR; Li, XZ; Wu, HF; Xu, JD; Yang, D | 1 |
| Liu, HB; Liu, ZH; Wang, J | 1 |
| Meng, F; Nie, P; Shen, C; Wei, X; Zhang, J | 1 |
| Cao, Y; Chen, J; Chen, X; Hu, X; Li, X; Liu, H; Lu, S; Nie, J; Wu, X; Yang, Z; Zhao, X; Zhu, J | 1 |
| Liang, L; Lu, M; Maslov, LN; Wang, H; Wang, J; Yang, J; Zhang, J | 1 |
| Lu, M; Luan, A; Tang, F; Wang, H; Yang, J; Yang, Y; Zhang, J; Zhang, S | 1 |
| Bai, Y; Chen, QF; Chen, YY; Fan, JY; Han, JY; He, B; He, K; Li, Q; Liu, YY; Lv, AP; Pan, CS; Sun, K; Wang, CS; Yan, L | 1 |
| Han, R; He, X; Hou, X; Hu, J; Lu, M; Mei, M; Tang, F; Wang, H; Xu, C | 1 |
| Han, R; Hu, J; Lu, M; Mei, M; Tang, F; Wang, H; Xu, C; Yang, J; Zhou, M | 1 |
| Hu, Z; Liu, Y; Ma, C; Shi, H; Wu, D; Zhou, J | 1 |
11 other study(ies) available for astragaloside a and Cardiomegaly
| Article | Year |
|---|---|
Astragaloside IV derivative HHQ16 ameliorates infarction-induced hypertrophy and heart failure through degradation of lncRNA4012/9456.
Topics: Animals; Cardiomegaly; Heart Failure; Humans; Mice; Myocardial Infarction; Myocytes, Cardiac | 2023 |
Astragaloside IV Prevents Cardiac Remodeling in the Apolipoprotein E-Deficient Mice by Regulating Cardiac Homeostasis and Oxidative Stress.
Topics: Animals; Apolipoproteins E; Apoptosis; Cardiomegaly; Cardiotonic Agents; Female; Fibrosis; Gene Deletion; Hypercholesterolemia; Lipids; Male; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Oxidative Stress; Saponins; Transcriptome; Triterpenes; Ventricular Dysfunction, Left | 2017 |
Astragaloside IV protects against the pathological cardiac hypertrophy in mice.
Topics: Angiotensin II; Animals; Apoptosis; Cardiomegaly; Cardiotonic Agents; Enzyme Activation; Inflammation; Intracellular Signaling Peptides and Proteins; Male; Mice, Inbred C57BL; Myocardium; Myocytes, Cardiac; Phosphorylation; Pressure; Protein Serine-Threonine Kinases; Saponins; Signal Transduction; Triterpenes | 2018 |
Astragaloside IV Exerts a Myocardial Protective Effect against Cardiac Hypertrophy in Rats, Partially via Activating the Nrf2/HO-1 Signaling Pathway.
Topics: Animals; Cardiomegaly; Cell Line; Cell Survival; Heme Oxygenase-1; NF-E2-Related Factor 2; Rats; Reactive Oxygen Species; Saponins; Signal Transduction; Triterpenes | 2019 |
Genetic and pharmacological inhibition of Rheb1-mTORC1 signaling exerts cardioprotection against adverse cardiac remodeling in mice.
Topics: Animals; Apoptosis; Cardiomegaly; Cardiotonic Agents; Cells, Cultured; Drug Evaluation, Preclinical; Gene Deletion; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Inbred C57BL; Monomeric GTP-Binding Proteins; Multiprotein Complexes; Myocardial Infarction; Myocytes, Cardiac; Neuropeptides; Ras Homolog Enriched in Brain Protein; Saponins; Signal Transduction; TOR Serine-Threonine Kinases; Triterpenes; Ventricular Remodeling | 2013 |
Astragaloside IV protects against cardiac hypertrophy via inhibiting the Ca2+/CaN signaling pathway.
Topics: Animals; Atrial Natriuretic Factor; Calcineurin; Calcium Signaling; Cardiomegaly; Cardiotonic Agents; Cells, Cultured; Drugs, Chinese Herbal; Lipopolysaccharides; Myocytes, Cardiac; Natriuretic Peptide, Brain; NFATC Transcription Factors; Rats; Saponins; Signal Transduction; Triterpenes | 2014 |
Astragaloside IV protects against isoproterenol-induced cardiac hypertrophy by regulating NF-κB/PGC-1α signaling mediated energy biosynthesis.
Topics: Animals; Atrial Natriuretic Factor; Cardiomegaly; Down-Regulation; Energy Metabolism; Gene Knockdown Techniques; Heart Ventricles; Hemodynamics; Isoproterenol; Male; Mitochondria; Myocytes, Cardiac; Natriuretic Peptide, Brain; NF-kappa B; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats; Rats, Sprague-Dawley; RNA, Messenger; RNA, Small Interfering; Saponins; Signal Transduction; Transcription Factor RelA; Transcription Factors; Triterpenes | 2015 |
QiShenYiQi Pills, a compound in Chinese medicine, protects against pressure overload-induced cardiac hypertrophy through a multi-component and multi-target mode.
Topics: Animals; Cardiomegaly; Drugs, Chinese Herbal; Energy Metabolism; Gene Expression Regulation; Ginsenosides; Heart; Myocardium; Oxidative Stress; Pressure; Proteomics; Rats; Rats, Sprague-Dawley; Saponins; Triterpenes | 2015 |
Astragaloside IV attenuates apoptosis of hypertrophic cardiomyocyte through inhibiting oxidative stress and calpain-1 activation.
Topics: 2-Propanol; Animals; Antioxidants; Apoptosis; Calpain; Cardiomegaly; Cardiotonic Agents; Cell Line; Gene Expression Regulation; Membrane Potential, Mitochondrial; Mitochondria; Myocytes, Cardiac; Oxidative Stress; Rats; Rats, Sprague-Dawley; Saponins; Triterpenes | 2015 |
Astragaloside IV improves the isoproterenol-induced vascular dysfunction via attenuating eNOS uncoupling-mediated oxidative stress and inhibiting ROS-NF-κB pathways.
Topics: Animals; Anti-Inflammatory Agents; Aorta; Astragalus propinquus; Cardiomegaly; Cytokines; Humans; Isoproterenol; Male; NF-kappa B; Nitric Oxide Synthase Type III; Oxidative Coupling; Peripheral Vascular Diseases; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Saponins; Signal Transduction; Triterpenes | 2016 |
[Inhibitory effect on activated renin-angiotensin system by astragaloside IV in rats with pressure-overload induced cardiac hypertrophy].
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Enzyme-Linked Immunosorbent Assay; Hypertrophy, Left Ventricular; Male; Peptidyl-Dipeptidase A; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Saponins; Triterpenes | 2009 |