astemizole has been researched along with Vertigo in 4 studies
Astemizole: Antihistamine drug now withdrawn from the market in many countries because of rare but potentially fatal side effects.
astemizole : A piperidine compound having a 2-(4-methoxyphenyl)ethyl group at the 1-position and an N-[(4-fluorobenzyl)benzimidazol-2-yl]amino group at the 4-position.
Vertigo: An illusion of movement, either of the external world revolving around the individual or of the individual revolving in space. Vertigo may be associated with disorders of the inner ear (EAR, INNER); VESTIBULAR NERVE; BRAINSTEM; or CEREBRAL CORTEX. Lesions in the TEMPORAL LOBE and PARIETAL LOBE may be associated with FOCAL SEIZURES that may feature vertigo as an ictal manifestation. (From Adams et al., Principles of Neurology, 6th ed, pp300-1)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty-eight patients with chronic vertigo and positional and/or spontaneous nystagmus finished a double-blind study to determine the efficacy of astemizole on nystagmus and its symptoms." | 9.06 | Astemizole. Its use in the treatment of patients with chronic vertigo. ( Jackson, RT; Turner, JS, 1987) |
| "Thirty-eight patients with chronic vertigo and positional and/or spontaneous nystagmus finished a double-blind study to determine the efficacy of astemizole on nystagmus and its symptoms." | 5.06 | Astemizole. Its use in the treatment of patients with chronic vertigo. ( Jackson, RT; Turner, JS, 1987) |
| " Our results demonstrate that: i) 100 microliters ethanol induced robust behavioral changes, which was used in further experiments; ii) the clinically used antivertigo agent, astemizole, significantly reduced the rotational behavior in UL rats; iii) the more potent H3 antagonists, thioperamide and GT-2016, were more efficacious than betahistine, a mixed H3 antagonist and H1 agonist." | 3.70 | Histaminergic ligands attenuate barrel rotation in rats following unilateral labyrinthectomy. ( Brioni, JD; Hancock, AA; O'Neill, AB; Pan, JB; Sullivan, JP, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Turner, JS | 2 |
| Jackson, RT | 2 |
| Pan, JB | 1 |
| O'Neill, AB | 1 |
| Hancock, AA | 1 |
| Sullivan, JP | 1 |
| Brioni, JD | 1 |
| Wexler, DB | 1 |
1 trial available for astemizole and Vertigo
| Article | Year |
|---|---|
Astemizole. Its use in the treatment of patients with chronic vertigo.
Topics: Adult; Aged; Astemizole; Benzimidazoles; Chronic Disease; Consumer Behavior; Dizziness; Double-Blind | 1987 |
3 other studies available for astemizole and Vertigo
| Article | Year |
|---|---|
Astemizole: its use in patients with chronic vertigo and eng signs--a pilot study of a new drug.
Topics: Adult; Astemizole; Benzimidazoles; Chronic Disease; Electronystagmography; Female; Histamine H1 Anta | 1983 |
Histaminergic ligands attenuate barrel rotation in rats following unilateral labyrinthectomy.
Topics: Animals; Astemizole; Behavior, Animal; Ear, Inner; Ethanol; Imidazoles; Male; Rats; Rats, Long-Evans | 1998 |
Astemizole for treatment of chronic vertigo.
Topics: Astemizole; Benzimidazoles; Chronic Disease; Humans; Research Design; Vertigo | 1987 |