astemizole has been researched along with Tachycardia in 8 studies
Astemizole: Antihistamine drug now withdrawn from the market in many countries because of rare but potentially fatal side effects.
astemizole : A piperidine compound having a 2-(4-methoxyphenyl)ethyl group at the 1-position and an N-[(4-fluorobenzyl)benzimidazol-2-yl]amino group at the 4-position.
Tachycardia: Abnormally rapid heartbeat, usually with a HEART RATE above 100 beats per minute for adults. Tachycardia accompanied by disturbance in the cardiac depolarization (cardiac arrhythmia) is called tachyarrhythmia.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We report a case in which a deliberate overdose of astemizole was associated with Mobitz type two heart block and prolongation of the QT interval, causing the so-called torsade-de-pointes ventricular tachycardia." | 3.68 | Astemizole-induced ventricular arrhythmias: an unexpected cause of convulsions. ( Clark, A; Love, H, 1991) |
| "Ebastine also inhibit potassium channels, cloned human Kv 1." | 2.41 | [The effect of second generation histamine antagonists on the heart]. ( Górska, M; Grzelewska-Rzymowska, I; Pietrzkowicz, M, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (37.50) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Porterfield, LM | 1 |
| Grzelewska-Rzymowska, I | 1 |
| Pietrzkowicz, M | 1 |
| Górska, M | 1 |
| Leor, J | 1 |
| Harman, M | 1 |
| Rabinowitz, B | 1 |
| Mozes, B | 1 |
| Clark, A | 1 |
| Love, H | 1 |
| Bastecký, J | 1 |
| Kvasnicka, J | 1 |
| Vortel, J | 1 |
| Tauchman, M | 1 |
| Wasylivová, V | 1 |
| Craft, TM | 1 |
| Simons, FE | 1 |
| Kesselman, MS | 1 |
| Giddins, NG | 1 |
| Pelech, AN | 1 |
| Simons, KJ | 1 |
| Snook, J | 1 |
| Boothman-Burrell, D | 1 |
| Watkins, J | 1 |
| Colin-Jones, D | 1 |
1 review available for astemizole and Tachycardia
| Article | Year |
|---|---|
[The effect of second generation histamine antagonists on the heart].
Topics: Animals; Area Under Curve; Astemizole; Butyrophenones; Electrocardiography; Heart; Histamine H1 Anta | 2001 |
7 other studies available for astemizole and Tachycardia
| Article | Year |
|---|---|
What's causing this arrhythmia?
Topics: Adult; Anti-Allergic Agents; Antidepressive Agents, Second-Generation; Astemizole; Drug Interactions | 1998 |
Giant U waves and associated ventricular tachycardia complicating astemizole overdose: successful therapy with intravenous magnesium.
Topics: Adult; Astemizole; Benzimidazoles; Drug Overdose; Electrocardiography; Histamine H1 Antagonists; Hum | 1991 |
Astemizole-induced ventricular arrhythmias: an unexpected cause of convulsions.
Topics: Adolescent; Astemizole; Drug Overdose; Electrocardiography; Female; Heart Block; Humans; Seizures; T | 1991 |
[Severe antihistamine poisoning complicated by ventricular tachycardia].
Topics: Adult; Astemizole; Benzhydryl Compounds; Benzimidazoles; Female; Histamine H1 Antagonists; Humans; T | 1990 |
Torsade de pointes after astemizole overdose.
Topics: Adolescent; Astemizole; Benzimidazoles; Electrocardiography; Female; Histamine H1 Antagonists; Human | 1986 |
Astemizole-induced torsade de pointes.
Topics: Adolescent; Astemizole; Benzimidazoles; Female; Histamine H1 Antagonists; Humans; Rhinitis, Allergic | 1988 |
Torsade de pointes ventricular tachycardia associated with astemizole overdose.
Topics: Adolescent; Astemizole; Benzimidazoles; Histamine H1 Antagonists; Humans; Male; Tachycardia | 1988 |