astemizole has been researched along with Retinoblastoma in 1 studies
Astemizole: Antihistamine drug now withdrawn from the market in many countries because of rare but potentially fatal side effects.
astemizole : A piperidine compound having a 2-(4-methoxyphenyl)ethyl group at the 1-position and an N-[(4-fluorobenzyl)benzimidazol-2-yl]amino group at the 4-position.
Retinoblastoma: A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Retinoblastoma is the most common pediatric intraocular malignant tumor." | 1.56 | Eag1 Gene and Protein Expression in Human Retinoblastoma Tumors and its Regulation by pRb in HeLa Cells. ( Avalos-Fuentes, A; Cabrera-Muñoz, ML; Camacho, J; Castro-Magdonel, BE; Chávez-López, MG; Escobar, Y; Garrido, E; Hernández-Gallegos, E; Ortiz, CS; Ponce-Castañeda, MV; Sánchez-Ramos, J; Vera, E; Zúñiga-García, V, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chávez-López, MG | 1 |
| Zúñiga-García, V | 1 |
| Castro-Magdonel, BE | 1 |
| Vera, E | 1 |
| Garrido, E | 1 |
| Sánchez-Ramos, J | 1 |
| Ponce-Castañeda, MV | 1 |
| Cabrera-Muñoz, ML | 1 |
| Escobar, Y | 1 |
| Ortiz, CS | 1 |
| Hernández-Gallegos, E | 1 |
| Avalos-Fuentes, A | 1 |
| Camacho, J | 1 |
1 other study available for astemizole and Retinoblastoma
| Article | Year |
|---|---|
Eag1 Gene and Protein Expression in Human Retinoblastoma Tumors and its Regulation by pRb in HeLa Cells.
Topics: Astemizole; Cell Line, Tumor; Cell Proliferation; Child, Preschool; Ether-A-Go-Go Potassium Channels | 2020 |