astemizole has been researched along with Pink Eye in 6 studies
Astemizole: Antihistamine drug now withdrawn from the market in many countries because of rare but potentially fatal side effects.
astemizole : A piperidine compound having a 2-(4-methoxyphenyl)ethyl group at the 1-position and an N-[(4-fluorobenzyl)benzimidazol-2-yl]amino group at the 4-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The efficacy of astemizole, a new, long acting, oral histamine H1-receptor antagonist was compared to placebo for the treatment of allergic rhinitis and conjunctivitis during the grass pollen season of 1982." | 9.05 | Astemizole, a potent histamine H1-receptor antagonist: effect in allergic rhinoconjunctivitis, on antigen and histamine induced skin weal responses and relationship to serum levels. ( Emanuel, MB; Holgate, ST; Howarth, PH, 1984) |
| "If rhinoconjunctivitis was inadequately controlled with the trial medications, pressurized steroid nasal spray and/or antihistamine-decongestant eye drops were used in the minimum dose that would ensure relief." | 6.66 | Comparison of beclomethasone dipropionate aqueous nasal spray, astemizole, and the combination in the prophylactic treatment of ragweed pollen-induced rhinoconjunctivitis. ( Dolovich, J; Hargreave, FE; Juniper, EF; Kline, PA, 1989) |
| "The efficacy of astemizole, a new, long acting, oral histamine H1-receptor antagonist was compared to placebo for the treatment of allergic rhinitis and conjunctivitis during the grass pollen season of 1982." | 5.05 | Astemizole, a potent histamine H1-receptor antagonist: effect in allergic rhinoconjunctivitis, on antigen and histamine induced skin weal responses and relationship to serum levels. ( Emanuel, MB; Holgate, ST; Howarth, PH, 1984) |
| "In a double blind study patients with hay fever were treated with Astemizole or Terfenadine for 3 to 4 weeks, 12 patients with Astemizole and 6 patients with Terfenadine." | 5.05 | [Hay fever therapy with 2 non-sedating antihistaminics]. ( Bäurle, G, 1985) |
| "If rhinoconjunctivitis was inadequately controlled with the trial medications, pressurized steroid nasal spray and/or antihistamine-decongestant eye drops were used in the minimum dose that would ensure relief." | 2.66 | Comparison of beclomethasone dipropionate aqueous nasal spray, astemizole, and the combination in the prophylactic treatment of ragweed pollen-induced rhinoconjunctivitis. ( Dolovich, J; Hargreave, FE; Juniper, EF; Kline, PA, 1989) |
| "Astemizole was superior to placebo and the classical antihistamines like Clemastine, Terfenadine, Ketotifen, Mequitazine, pheniramine and Chlorphenamine." | 2.66 | [Total review of all results collected worldwide with astemizole (Hismanal)]. ( Rombaut, N; Vanden Bussche, G, 1985) |
| "Astemizole is an H1-histamine receptor antagonist with a long duration of action permitting once daily administration." | 2.37 | Astemizole. A review of its pharmacodynamic properties and therapeutic efficacy. ( Avery, GS; Brogden, RN; Heel, RC; Richards, DM; Speight, TM, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Howarth, PH | 1 |
| Emanuel, MB | 1 |
| Holgate, ST | 1 |
| Richards, DM | 1 |
| Brogden, RN | 1 |
| Heel, RC | 1 |
| Speight, TM | 1 |
| Avery, GS | 1 |
| Juniper, EF | 1 |
| Kline, PA | 1 |
| Hargreave, FE | 1 |
| Dolovich, J | 1 |
| Rombaut, N | 1 |
| Vanden Bussche, G | 1 |
| Bäurle, G | 1 |
| Stokes, TC | 1 |
| Feinberg, G | 1 |
1 review available for astemizole and Pink Eye
| Article | Year |
|---|---|
Astemizole. A review of its pharmacodynamic properties and therapeutic efficacy.
Topics: Animals; Astemizole; Benzimidazoles; Conjunctivitis; Dermatitis, Contact; Histamine H1 Antagonists; | 1984 |
5 trials available for astemizole and Pink Eye
| Article | Year |
|---|---|
Astemizole, a potent histamine H1-receptor antagonist: effect in allergic rhinoconjunctivitis, on antigen and histamine induced skin weal responses and relationship to serum levels.
Topics: Adolescent; Adult; Astemizole; Benzimidazoles; Body Weight; Clinical Trials as Topic; Conjunctivitis | 1984 |
Comparison of beclomethasone dipropionate aqueous nasal spray, astemizole, and the combination in the prophylactic treatment of ragweed pollen-induced rhinoconjunctivitis.
Topics: Administration, Intranasal; Adolescent; Adult; Aged; Astemizole; Beclomethasone; Benzimidazoles; Con | 1989 |
[Total review of all results collected worldwide with astemizole (Hismanal)].
Topics: Astemizole; Beclomethasone; Benzimidazoles; Bronchitis; Clinical Trials as Topic; Conjunctivitis; Do | 1985 |
[Hay fever therapy with 2 non-sedating antihistaminics].
Topics: Arousal; Astemizole; Benzhydryl Compounds; Benzimidazoles; Clinical Trials as Topic; Conjunctivitis; | 1985 |
Blocking of histamine-induced conjunctivitis by the oral antihistamine, astemizole.
Topics: Administration, Oral; Adult; Astemizole; Benzimidazoles; Conjunctivitis; Double-Blind Method; Histam | 1988 |