Page last updated: 2024-10-23

astemizole and Motion Sickness

astemizole has been researched along with Motion Sickness in 2 studies

Astemizole: Antihistamine drug now withdrawn from the market in many countries because of rare but potentially fatal side effects.
astemizole : A piperidine compound having a 2-(4-methoxyphenyl)ethyl group at the 1-position and an N-[(4-fluorobenzyl)benzimidazol-2-yl]amino group at the 4-position.

Motion Sickness: Disorder caused by motion. It includes sea sickness, train sickness, roller coaster rides, rocking chair, hammock swing, car sickness, air sickness, or SPACE MOTION SICKNESS. Symptoms include nausea, vomiting and/or dizziness.

Research Excerpts

ExcerptRelevanceReference
"Astemizole was orally administered to 20 subjects in a randomized, double-blind design to assess the efficacy of this peripherally active antihistamine as an antimotion sickness drug possessing no central side-effects."9.06Lack of effects of astemizole on vestibular ocular reflex, motion sickness, and cognitive performance in man. ( Calkins, DS; Cintron, N; Homick, JL; Kohl, RL, 1987)
"Astemizole was orally administered to 20 subjects in a randomized, double-blind design to assess the efficacy of this peripherally active antihistamine as an antimotion sickness drug possessing no central side-effects."5.06Lack of effects of astemizole on vestibular ocular reflex, motion sickness, and cognitive performance in man. ( Calkins, DS; Cintron, N; Homick, JL; Kohl, RL, 1987)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kohl, RL2
Homick, JL1
Cintron, N1
Calkins, DS1

Trials

2 trials available for astemizole and Motion Sickness

ArticleYear
Is there a role for nonsedating antihistamines in motion sickness? Fallout from space research may soon benefit your patients.
    The Journal of respiratory diseases, 1991, Volume: 12, Issue:4 Suppl

    Topics: Aerospace Medicine; Astemizole; Coriolis Force; Doxepin; Drug Evaluation; Head Movements; Histamine

1991
Lack of effects of astemizole on vestibular ocular reflex, motion sickness, and cognitive performance in man.
    Aviation, space, and environmental medicine, 1987, Volume: 58, Issue:12

    Topics: Adolescent; Adult; Astemizole; Benzimidazoles; Clinical Trials as Topic; Cognition; Double-Blind Met

1987