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astemizole and Macular Edema

astemizole has been researched along with Macular Edema in 1 studies

Astemizole: Antihistamine drug now withdrawn from the market in many countries because of rare but potentially fatal side effects.
astemizole : A piperidine compound having a 2-(4-methoxyphenyl)ethyl group at the 1-position and an N-[(4-fluorobenzyl)benzimidazol-2-yl]amino group at the 4-position.

Macular Edema: Fluid accumulation in the outer layer of the MACULA LUTEA that results from intraocular or systemic insults. It may develop in a diffuse pattern where the macula appears thickened or it may acquire the characteristic petaloid appearance referred to as cystoid macular edema. Although macular edema may be associated with various underlying conditions, it is most commonly seen following intraocular surgery, venous occlusive disease, DIABETIC RETINOPATHY, and posterior segment inflammatory disease. (From Survey of Ophthalmology 2004; 49(5) 470-90)

Research Excerpts

ExcerptRelevanceReference
"To compare the effects of astemizole, an antihistamine, versus placebo on the 1-year course of diabetic macular edema (DME) and to illustrate use of a modified ETDRS system for grading areas of retinal thickening and hard exudates that may be useful in clinical trials of treatments for this disorder."9.12An extension of the Early Treatment Diabetic Retinopathy Study (ETDRS) system for grading of diabetic macular edema in the Astemizole Retinopathy Trial. ( Blankenship, GW; Brod, RD; Davis, MD; Gardner, TW; Hubbard, L; Kunselman, A; Larsen, ML; Lund-Andersen, H; Parving, HH; Post-Hansen, H; Quillen, DA; Reimers, J; Sander, B; Tenhave, T; Wilmarth, MH, 2006)
"To compare the effects of astemizole, an antihistamine, versus placebo on the 1-year course of diabetic macular edema (DME) and to illustrate use of a modified ETDRS system for grading areas of retinal thickening and hard exudates that may be useful in clinical trials of treatments for this disorder."5.12An extension of the Early Treatment Diabetic Retinopathy Study (ETDRS) system for grading of diabetic macular edema in the Astemizole Retinopathy Trial. ( Blankenship, GW; Brod, RD; Davis, MD; Gardner, TW; Hubbard, L; Kunselman, A; Larsen, ML; Lund-Andersen, H; Parving, HH; Post-Hansen, H; Quillen, DA; Reimers, J; Sander, B; Tenhave, T; Wilmarth, MH, 2006)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gardner, TW1
Sander, B1
Larsen, ML1
Kunselman, A1
Tenhave, T1
Lund-Andersen, H1
Reimers, J1
Hubbard, L1
Blankenship, GW1
Quillen, DA1
Brod, RD1
Wilmarth, MH1
Post-Hansen, H1
Parving, HH1
Davis, MD1

Trials

1 trial available for astemizole and Macular Edema

ArticleYear
An extension of the Early Treatment Diabetic Retinopathy Study (ETDRS) system for grading of diabetic macular edema in the Astemizole Retinopathy Trial.
    Current eye research, 2006, Volume: 31, Issue:6

    Topics: Adult; Astemizole; Blood-Retinal Barrier; Diabetic Retinopathy; Diagnostic Techniques, Ophthalmologi

2006