astemizole has been researched along with Heart Arrest in 2 studies
Astemizole: Antihistamine drug now withdrawn from the market in many countries because of rare but potentially fatal side effects.
astemizole : A piperidine compound having a 2-(4-methoxyphenyl)ethyl group at the 1-position and an N-[(4-fluorobenzyl)benzimidazol-2-yl]amino group at the 4-position.
Heart Arrest: Cessation of heart beat or MYOCARDIAL CONTRACTION. If it is treated within a few minutes, heart arrest can be reversed in most cases to normal cardiac rhythm and effective circulation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "QT interval prolongation and torsade de pointes are associated with astemizole intake and have been ascribed to block the repolarizing K+ currents, specifically the rapidly activating component of the delayed rectifier iKr." | 7.69 | Torsade de pointes with an antihistamine metabolite: potassium channel blockade with desmethylastemizole. ( Hoon, TJ; January, CT; Mohammad, S; Studenik, C; Vorperian, VR; Zhou, Z, 1996) |
| "QT interval prolongation and torsade de pointes are associated with astemizole intake and have been ascribed to block the repolarizing K+ currents, specifically the rapidly activating component of the delayed rectifier iKr." | 3.69 | Torsade de pointes with an antihistamine metabolite: potassium channel blockade with desmethylastemizole. ( Hoon, TJ; January, CT; Mohammad, S; Studenik, C; Vorperian, VR; Zhou, Z, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Broadhurst, P | 1 |
| Nathan, AW | 1 |
| Vorperian, VR | 1 |
| Zhou, Z | 1 |
| Mohammad, S | 1 |
| Hoon, TJ | 1 |
| Studenik, C | 1 |
| January, CT | 1 |
2 other studies available for astemizole and Heart Arrest
| Article | Year |
|---|---|
Cardiac arrest in a young woman with the long QT syndrome and concomitant astemizole ingestion.
Topics: Adult; Astemizole; Electrocardiography; Female; Heart Arrest; Humans; Long QT Syndrome | 1993 |
Torsade de pointes with an antihistamine metabolite: potassium channel blockade with desmethylastemizole.
Topics: Aged; Aged, 80 and over; Animals; Astemizole; Electrocardiography; Female; Heart; Heart Arrest; Hist | 1996 |