Page last updated: 2024-10-23

astemizole and Hay Fever

astemizole has been researched along with Hay Fever in 60 studies

Astemizole: Antihistamine drug now withdrawn from the market in many countries because of rare but potentially fatal side effects.
astemizole : A piperidine compound having a 2-(4-methoxyphenyl)ethyl group at the 1-position and an N-[(4-fluorobenzyl)benzimidazol-2-yl]amino group at the 4-position.

Research Excerpts

ExcerptRelevanceReference
"A study was carried out in general practice during the summer months of 1985 to compare the efficacy and tolerance of astemizole suspension with terfenadine suspension in the treatment of paediatric hay fever."9.06Astemizole suspension in the maintenance treatment of paediatric hay fever: a comparison with terfenadine suspension. ( Grillage, MG; Harcup, JW; Huddlestone, L; Mayhew, SR, 1986)
"An open, parallel group study was carried out in 95 hay fever patients during the 1984 season to compare the efficacy of oral astemizole with that of topical sodium cromoglycate."9.06A comparison of oral astemizole with topical sodium cromoglycate in the treatment of hay fever. ( Harcup, JW; Patel, KR; Tristram, SJ, 1986)
"In this double-blind study, 65 patients with hay fever were treated for 14 days with either loratadine 10 mg once daily, astemizole 10 mg once daily, or placebo."9.06Double-blind comparison of loratadine (SCH 29851), astemizole, and placebo in hay fever with special regard to onset of action. ( Oei, HD, 1988)
"In this double-blind study forty-seven patients with hay fever were treated for 8 days with either terfenadine 60 mg twice a day, astemizole 10 mg once a day or placebo."9.05Double-blind comparison of astemizole, terfenadine and placebo in hay fever with special regard to onset of action. ( Bigliardi, P; Girard, JP; Henauer, SA; Sommacal-Schopf, D, 1985)
"The efficacy of astemizole, a new, long acting, oral histamine H1-receptor antagonist was compared to placebo for the treatment of allergic rhinitis and conjunctivitis during the grass pollen season of 1982."9.05Astemizole, a potent histamine H1-receptor antagonist: effect in allergic rhinoconjunctivitis, on antigen and histamine induced skin weal responses and relationship to serum levels. ( Emanuel, MB; Holgate, ST; Howarth, PH, 1984)
"Ninety patients participated in a randomised, double blind, placebo controlled comparison of terfenadine with astemizole in the treatment of hay fever."9.05Comparative trial of two non-sedative H1 antihistamines, terfenadine and astemizole, for hay fever. ( Holgate, ST; Howarth, PH, 1984)
"A double-blind parallel trial of astemizole, pheniramine and placebo was carried out in 51 patients with hay fever."9.05Astemizole in the treatment of hay fever. ( Binder, E; Grahne, B; Holopainen, E; Malmberg, H; Savolainen, S; Sundberg, S, 1983)
"Astemizole, a new long acting and non sedative antihistamine, and Terfenadine, an H1 antagonist widely used, were compared in a randomized double-blind study over 4 weeks in 55 patients suffering from hay fever."7.67A double-blind comparative trial of astemizole and terfenadine for the treatment of hay fever. ( Cilli, P; Negrini, AC; Troise, C; Voltolini, S, 1989)
"The efficacy and side effects of the oral H1-antihistamine, astemizole, were compared with those of nasal beclomethasone in 158 adult birch-pollen allergic hay fever patients."7.67Efficacy of an oral antihistamine, astemizole, as compared to a nasal steroid spray in hay fever. ( Gottberg, L; Heilborn, H; Norrlind, K; Pegelow, KO; Salomonsson, P, 1988)
"85 patients suffering from pollinosis wee studied randomly on single-blind basis during the hay fever season of 1983."6.66[Comparison of astemizole and terfenadine in maintenance therapy of hay fever]. ( Repp, V, 1985)
"A study was carried out in general practice during the summer months of 1985 to compare the efficacy and tolerance of astemizole suspension with terfenadine suspension in the treatment of paediatric hay fever."5.06Astemizole suspension in the maintenance treatment of paediatric hay fever: a comparison with terfenadine suspension. ( Grillage, MG; Harcup, JW; Huddlestone, L; Mayhew, SR, 1986)
"An open, parallel group study was carried out in 95 hay fever patients during the 1984 season to compare the efficacy of oral astemizole with that of topical sodium cromoglycate."5.06A comparison of oral astemizole with topical sodium cromoglycate in the treatment of hay fever. ( Harcup, JW; Patel, KR; Tristram, SJ, 1986)
"In this double-blind study, 65 patients with hay fever were treated for 14 days with either loratadine 10 mg once daily, astemizole 10 mg once daily, or placebo."5.06Double-blind comparison of loratadine (SCH 29851), astemizole, and placebo in hay fever with special regard to onset of action. ( Oei, HD, 1988)
"The efficacy of astemizole, a new, long acting, oral histamine H1-receptor antagonist was compared to placebo for the treatment of allergic rhinitis and conjunctivitis during the grass pollen season of 1982."5.05Astemizole, a potent histamine H1-receptor antagonist: effect in allergic rhinoconjunctivitis, on antigen and histamine induced skin weal responses and relationship to serum levels. ( Emanuel, MB; Holgate, ST; Howarth, PH, 1984)
"Ninety patients participated in a randomised, double blind, placebo controlled comparison of terfenadine with astemizole in the treatment of hay fever."5.05Comparative trial of two non-sedative H1 antihistamines, terfenadine and astemizole, for hay fever. ( Holgate, ST; Howarth, PH, 1984)
"In this double-blind study forty-seven patients with hay fever were treated for 8 days with either terfenadine 60 mg twice a day, astemizole 10 mg once a day or placebo."5.05Double-blind comparison of astemizole, terfenadine and placebo in hay fever with special regard to onset of action. ( Bigliardi, P; Girard, JP; Henauer, SA; Sommacal-Schopf, D, 1985)
"A double-blind parallel trial of astemizole, pheniramine and placebo was carried out in 51 patients with hay fever."5.05Astemizole in the treatment of hay fever. ( Binder, E; Grahne, B; Holopainen, E; Malmberg, H; Savolainen, S; Sundberg, S, 1983)
"In a double blind study patients with hay fever were treated with Astemizole or Terfenadine for 3 to 4 weeks, 12 patients with Astemizole and 6 patients with Terfenadine."5.05[Hay fever therapy with 2 non-sedating antihistaminics]. ( Bäurle, G, 1985)
"It has also proved useful in the treatment of allergic conjunctivitis and chronic urticaria."3.76[A new H1-blocking antihistamine. Critical review of pharmacological and clinical studies]. ( Emmi, L; Rossi, O, 1988)
" Twenty subjects with hay fever were given astemizole (10 mg/d) for 7 days."3.68Skin test inhibition by astemizole. ( He, H; Yang, X; Yue, F; Zhang, H; Zhang, R, 1992)
" Twenty cases of hay fever were selected for astemizole administration, 10 mg/d for 7 days."3.68[Inhibition of skin test by astemizole]. ( Zhang, H, 1992)
"Astemizole, a new long acting and non sedative antihistamine, and Terfenadine, an H1 antagonist widely used, were compared in a randomized double-blind study over 4 weeks in 55 patients suffering from hay fever."3.67A double-blind comparative trial of astemizole and terfenadine for the treatment of hay fever. ( Cilli, P; Negrini, AC; Troise, C; Voltolini, S, 1989)
"The efficacy and side effects of the oral H1-antihistamine, astemizole, were compared with those of nasal beclomethasone in 158 adult birch-pollen allergic hay fever patients."3.67Efficacy of an oral antihistamine, astemizole, as compared to a nasal steroid spray in hay fever. ( Gottberg, L; Heilborn, H; Norrlind, K; Pegelow, KO; Salomonsson, P, 1988)
"Parietaria pollinosis and cypress pollinosis, have been scarcely investigated, so far."2.70Second generation antihistamines in the treatment of seasonal allergic rhinitis due to Parietaria and cypress pollen. ( Bariletto, G; Caiaffa, MF; De Michele, G; Di Paola, R; Iudice, A; Macchia, L; Tursi, A, 2001)
"The histamine covariant was more important in the allergen effect of astemizole than in that of loratadine."2.69Changes in skin-test reactivity do not correlate with clinical efficacy of H1-blockers in seasonal allergic rhinitis. ( Bousquet, J; Cougnard, J; Czarlewski, W; Danzig, M; Michel, FB, 1998)
"Thus, ebastine is a useful alternative treatment for seasonal allergic rhinitis."2.68Clinical efficacy of ebastine in the treatment and prevention of seasonal allergic rhinitis. ( Peláez, A, 1996)
"Triamcinolone acetonide was superior to astemizole at weeks 1, 2, and 3 in reduction of the total nasal symptom score (p 2.68Comparison of triamcinolone acetonide nasal inhaler with astemizole in the treatment of ragweed-induced allergic rhinitis. ( Bernstein, DI; Busse, WW; Cohen, R; Creticos, PS; Graft, DF; Howland, WC; Lim, J; Lumry, WR; McNally, C; Pedinoff, AJ; Ratner, PH; Stokes, A, 1996)
" Both drugs were well tolerated and their adverse event profiles were similar."2.68Comparison of efficacy, safety, and skin test inhibition of cetirizine and astemizole. ( Berkowitz, RB; Dockhorn, R; Findlay, S; Howland, WC; Lockey, R; Mitchell, DQ; Woehler, T, 1996)
"Astemizole-treated patients showed statistically significantly more weight gain than did loratadine-treated patients."2.67Once daily loratadine versus astemizole once daily. ( Banov, C; Boggs, P; Chervinsky, P; Georgitis, J; Greenstein, S; Vande Souwe, R, 1994)
"05) for controlling nasal symptoms and safe in terms of short term biochemical and haematological changes and adverse effects noted."2.67Efficacy and safety of loratadine compared with astemizole in Malaysian patients with allergic rhinitis. ( Amin, MJ; Lee, ST, 1994)
" Study III (elimination half-life [t1/2 beta]): In 10 of the children from study II, t1/2 beta for astemizole plus DMA could be calculated (two samples) and was 10."2.67Pharmacokinetics of astemizole in children. ( Andlin-Sobocki, P; Blychert, LO; Möller, C, 1992)
"In a three-way, double-blind, crossover study the onset of action and effects at the end of the dosing interval of 10 mg/day astemizole, 10 mg/day loratadine and 120 mg/day terfenadine forte given for 3 days to six atopic volunteers were assessed using the Vienna challenge chamber (VCC)."2.67Onset and duration of the effects of three antihistamines in current use--astemizole, loratadine and terfenadine forte--studied during prolonged, controlled allergen challenges in volunteers. ( Berger, U; Horak, F; Jäger, S, 1992)
"The two antihistamines studied had no adverse effects on the performance of children."2.67Comparison of CNS adverse effects between astemizole and chlorpheniramine in children: a randomized, double-blind study. ( Feldman, W; Leikin, L; Peterson, R; Pong, AH; Shanon, A; Williams, V, 1993)
"85 patients suffering from pollinosis wee studied randomly on single-blind basis during the hay fever season of 1983."2.66[Comparison of astemizole and terfenadine in maintenance therapy of hay fever]. ( Repp, V, 1985)
"The efficacy of picumast dihydrochloride (3,4-dimethyl-7-[ 4-(4-chlorobenzyl)piperazine-1-yl]propoxycoumarine dihydrochloride) in a dosage of 2 mg o."2.66Double-blind multicenter controlled clinical study comparing the efficacy of picumast dihydrochloride versus astemizole and placebo in patients with seasonal allergic rhinitis. ( Franke, W; Messinger, D, 1989)
"Astemizole was superior to placebo and the classical antihistamines like Clemastine, Terfenadine, Ketotifen, Mequitazine, pheniramine and Chlorphenamine."2.66[Total review of all results collected worldwide with astemizole (Hismanal)]. ( Rombaut, N; Vanden Bussche, G, 1985)
"Triamcinolone is a commonly used synthetic corticosteroid that has recently been tested in a large clinical trial for chronic obstructive pulmonary disease and shown to have some benefits."2.41Triamcinolone: new and old indications. ( Doggrell, SA, 2001)
"Fluticasone propionate was superior to beclomethasone dipropionate in one trial according to patient evaluations of symptoms, but response to fluticasone propionate and beclomethasone dipropionate was similar in the second study."2.39Treatment of seasonal allergic rhinitis with fluticasone propionate aqueous nasal spray: review of comparator studies. ( Storms, WW, 1995)
"In this review of the current treatment of seasonal allergic rhinitis, the clinical studies that compare these four new second-generation H1-receptor antagonists are discussed."2.38H1-receptor antagonist treatment of seasonal allergic rhinitis. ( Kaiser, HB, 1990)
"Astemizole is an H1-histamine receptor antagonist with a long duration of action permitting once daily administration."2.37Astemizole. A review of its pharmacodynamic properties and therapeutic efficacy. ( Avery, GS; Brogden, RN; Heel, RC; Richards, DM; Speight, TM, 1984)
" Second-generation antihistamines have become increasingly popular because of their comparable efficacy and lower incidence of adverse effects relative to their first-generation counterparts, and the safety and efficacy of this drug class are established in the adult population."1.35Treatment of allergic rhinitis in infants and children: efficacy and safety of second-generation antihistamines and the leukotriene receptor antagonist montelukast. ( Moeller, ML; Nahata, MC; Phan, H, 2009)
" The cumulative results indicate that the nonsedative antihistamine terfenadine, given orally at a dosage of 60 mg twice daily, is effective in the treatment of seasonal allergic rhinitis in both adults and children."1.27The use of antihistamines for the treatment of airway disease. ( Meltzer, EO, 1988)

Research

Studies (60)

TimeframeStudies, this research(%)All Research%
pre-199032 (53.33)18.7374
1990's25 (41.67)18.2507
2000's3 (5.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Phan, H1
Moeller, ML1
Nahata, MC1
Wilson, JD1
Hillas, JL1
Howarth, PH2
Emanuel, MB3
Holgate, ST2
Obel, AO1
Richards, DM1
Brogden, RN1
Heel, RC1
Speight, TM1
Avery, GS1
Malmberg, H2
Holopainen, E2
Grahne, B1
Binder, E1
Savolainen, S1
Sundberg, S1
Frostad, AB1
L ofkvist, T1
Norell, I1
Svensson, G1
Wahlberg, P1
Ellertsen, B1
Negrini, AC2
Troise, C2
Voltolini, S2
Horak, F3
Bachert, C1
Janssens, M1
Storms, WW1
Lee, ST1
Amin, MJ1
Shanon, A1
Feldman, W1
Leikin, L1
Pong, AH1
Peterson, R1
Williams, V1
Herjavecz, I1
Karácsonyi, E1
Mülbacher, S1
Radics, K1
Szilágyi, R1
Gacsályi, I1
Chervinsky, P1
Georgitis, J1
Banov, C1
Boggs, P1
Vande Souwe, R1
Greenstein, S1
Toth, J1
Jäger, S2
Berger, U2
Stosiek, N1
Peters, KP1
von den Driesch, P1
Berkowitz, RB1
Dockhorn, R1
Lockey, R1
Findlay, S1
Howland, WC2
Mitchell, DQ1
Woehler, T1
Bernstein, DI1
Creticos, PS1
Busse, WW1
Cohen, R1
Graft, DF2
Lumry, WR1
Pedinoff, AJ1
Ratner, PH1
Lim, J1
Stokes, A1
McNally, C1
Bukstein, DA1
Biondi, RM1
Blumenthal, MM1
Dockhorn, RJ1
Filley, WV1
Fink, J1
Goldstein, S1
Hirsch, SR1
Joos, TH1
Melamed, J1
Rowe, MS1
Townley, RG1
Simola, M1
Böss, I1
Ruoppi, P1
Seppä, J1
Siivonen, L1
Suonpää, J1
Piepponen, T1
Peláez, A1
Day, JH1
Briscoe, MP1
Clark, RH1
Ellis, AK1
Gervais, P1
Bousquet, J1
Czarlewski, W1
Cougnard, J1
Danzig, M1
Michel, FB1
Doggrell, SA1
Macchia, L1
Caiaffa, MF1
Di Paola, R1
De Michele, G1
Bariletto, G1
Iudice, A1
Tursi, A1
Bedi, RS1
Yaniv, E1
Oppenheim, D1
Fuchs, C1
Businco, L1
Monteleone, A1
Ruggeri, L1
Cantani, A1
Chevallier, P1
Boner, AL1
Richelli, C1
Castellani, C1
Marchesi, E1
Andreoli, A1
Möller, C1
Andlin-Sobocki, P1
Blychert, LO1
Wood, SF3
Zhang, H2
He, H1
Zhang, R1
Yue, F1
Yang, X1
Kaiser, HB1
Cilli, P1
Franke, W1
Messinger, D1
Rombaut, N2
Vanden Bussche, G2
Repp, V1
Bäurle, G1
Freedman, BJ1
Knight, A1
Tristram, SJ1
Harcup, JW2
Patel, KR1
Sooknundun, M1
Kacker, SK1
Sundaram, KR1
Grillage, MG1
Mayhew, SR1
Huddlestone, L1
Ray, JA1
Zellweger, JP1
Zullig, R1
Emmi, L1
Rossi, O1
Salomonsson, P1
Gottberg, L1
Heilborn, H1
Norrlind, K1
Pegelow, KO1
Molkhou, P1
Meltzer, EO1
Oei, HD1
Shuster, S1
Juniper, EF1
White, J1
Dolovich, J1
Girard, JP1
Sommacal-Schopf, D1
Bigliardi, P1
Henauer, SA1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effectiveness of Montelukast Versus Intranasal Fluticasone Propionate in the Management of Allergic Rhinitis Among Children 02 to 05 Years of Age[NCT04957927]Phase 460 participants (Anticipated)Interventional2020-12-12Recruiting
Nasal Ocular Reflexes Contribute to Eye Symptoms in Patients With Allergic Rhinitis[NCT00117832]20 participants Interventional2005-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

7 reviews available for astemizole and Hay Fever

ArticleYear
Astemizole. A review of its pharmacodynamic properties and therapeutic efficacy.
    Drugs, 1984, Volume: 28, Issue:1

    Topics: Animals; Astemizole; Benzimidazoles; Conjunctivitis; Dermatitis, Contact; Histamine H1 Antagonists;

1984
Treatment of seasonal allergic rhinitis with fluticasone propionate aqueous nasal spray: review of comparator studies.
    Allergy, 1995, Volume: 50, Issue:23 Suppl

    Topics: Administration, Topical; Aerosols; Androstadienes; Anti-Inflammatory Agents; Astemizole; Beclomethas

1995
Triamcinolone: new and old indications.
    Expert opinion on pharmacotherapy, 2001, Volume: 2, Issue:7

    Topics: Administration, Intranasal; Adult; Aerosols; Androstadienes; Anti-Inflammatory Agents; Arthritis, Rh

2001
New strategies for the prevention and treatment of allergic rhinitis in children.
    Rhinology. Supplement, 1992, Volume: 13

    Topics: Allergens; Animals; Astemizole; Child; Histamine H1 Antagonists; Household Articles; Humans; Mites;

1992
Clinical experience with non-sedating antihistamines in paediatric allergic rhinitis.
    Rhinology. Supplement, 1992, Volume: 13

    Topics: Adolescent; Astemizole; Asthma; Child; Child, Preschool; Chlorpheniramine; Clinical Trials as Topic;

1992
H1-receptor antagonist treatment of seasonal allergic rhinitis.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:6 Pt 2

    Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Chlorpheniramine; Clemastine; Cyprohep

1990
[A new H1-blocking antihistamine. Critical review of pharmacological and clinical studies].
    Minerva medica, 1988, Volume: 79, Issue:3

    Topics: Animals; Astemizole; Benzimidazoles; Clinical Trials as Topic; Conjunctivitis, Allergic; Dogs; Doubl

1988

Trials

36 trials available for astemizole and Hay Fever

ArticleYear
Astemizole: a new long-acting antihistamine in the treatment of seasonal allergic rhinitis.
    Clinical allergy, 1983, Volume: 13, Issue:2

    Topics: Adolescent; Adult; Aged; Astemizole; Benzimidazoles; Clinical Trials as Topic; Double-Blind Method;

1983
Astemizole, a potent histamine H1-receptor antagonist: effect in allergic rhinoconjunctivitis, on antigen and histamine induced skin weal responses and relationship to serum levels.
    British journal of clinical pharmacology, 1984, Volume: 18, Issue:1

    Topics: Adolescent; Adult; Astemizole; Benzimidazoles; Body Weight; Clinical Trials as Topic; Conjunctivitis

1984
Comparative trial of two non-sedative H1 antihistamines, terfenadine and astemizole, for hay fever.
    Thorax, 1984, Volume: 39, Issue:9

    Topics: Adolescent; Adult; Astemizole; Benzhydryl Compounds; Benzimidazoles; Clinical Trials as Topic; Doubl

1984
Astemizole in the treatment of hay fever.
    Allergy, 1983, Volume: 38, Issue:4

    Topics: Adolescent; Adult; Astemizole; Benzimidazoles; Clinical Trials as Topic; Double-Blind Method; Female

1983
Oral antihistamine/decongestant treatment compared with intranasal corticosteroids in seasonal allergic rhinitis.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1995, Volume: 25, Issue:1

    Topics: Administration, Intranasal; Administration, Oral; Adolescent; Adult; Aged; Astemizole; Beclomethason

1995
Efficacy and safety of loratadine compared with astemizole in Malaysian patients with allergic rhinitis.
    Singapore medical journal, 1994, Volume: 35, Issue:6

    Topics: Astemizole; Double-Blind Method; Humans; Loratadine; Malaysia; Rhinitis, Allergic, Seasonal; Time Fa

1994
Comparison of CNS adverse effects between astemizole and chlorpheniramine in children: a randomized, double-blind study.
    Developmental pharmacology and therapeutics, 1993, Volume: 20, Issue:3-4

    Topics: Adolescent; Astemizole; Attention; Behavior; Central Nervous System; Child; Chlorpheniramine; Cross-

1993
Comparative clinical examination of Loderix (setastinum) and astemizole in pollenosis.
    Therapia Hungarica (English edition), 1993, Volume: 41, Issue:4

    Topics: Adult; Astemizole; Azepines; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Ra

1993
Once daily loratadine versus astemizole once daily.
    Annals of allergy, 1994, Volume: 73, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Astemizole; Child; Dose-Response Relationship, Drug; Double

1994
Effects of H1-receptor antagonists on nasal obstruction in atopic patients.
    Allergy, 1993, Volume: 48, Issue:4

    Topics: Adult; Airway Resistance; Allergens; Astemizole; Diagnosis, Computer-Assisted; Double-Blind Method;

1993
Comparison of efficacy, safety, and skin test inhibition of cetirizine and astemizole.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1996, Volume: 76, Issue:4

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Anti-Allergic Agents; Astemizole; Cetirizine; Child;

1996
Comparison of triamcinolone acetonide nasal inhaler with astemizole in the treatment of ragweed-induced allergic rhinitis.
    The Journal of allergy and clinical immunology, 1996, Volume: 97, Issue:3

    Topics: Administration, Intranasal; Administration, Oral; Adult; Allergens; Anti-Inflammatory Agents; Astemi

1996
Tilarin in combination with astemizole.
    Allergy, 1996, Volume: 51, Issue:28 Suppl

    Topics: Administration, Intranasal; Adolescent; Adult; Anti-Allergic Agents; Astemizole; Child; Double-Blind

1996
Astemizole in combination with pseudoephedrine in the treatment of seasonal allergic rhinitis.
    Rhinology, 1996, Volume: 34, Issue:1

    Topics: Adolescent; Adult; Allergens; Astemizole; Brompheniramine; Child; Drug Combinations; Ephedrine; Fema

1996
Clinical efficacy of ebastine in the treatment and prevention of seasonal allergic rhinitis.
    Drugs, 1996, Volume: 52 Suppl 1

    Topics: Astemizole; Butyrophenones; Double-Blind Method; Histamine H1 Antagonists; Humans; Piperidines; Rhin

1996
Onset of action and efficacy of terfenadine, astemizole, cetirizine, and loratadine for the relief of symptoms of allergic rhinitis.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1997, Volume: 79, Issue:2

    Topics: Adolescent; Adult; Anti-Allergic Agents; Astemizole; Cetirizine; Double-Blind Method; Environmental

1997
Changes in skin-test reactivity do not correlate with clinical efficacy of H1-blockers in seasonal allergic rhinitis.
    Allergy, 1998, Volume: 53, Issue:6

    Topics: Adolescent; Adult; Allergens; Astemizole; Child; Conjunctiva; Dose-Response Relationship, Drug; Doub

1998
Second generation antihistamines in the treatment of seasonal allergic rhinitis due to Parietaria and cypress pollen.
    Pharmacological research, 2001, Volume: 44, Issue:6

    Topics: Adult; Allergens; Astemizole; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Male; P

2001
Comparison of the effects of loratadine and astemizole in the treatment of children with seasonal allergic rhinoconjunctivitis.
    Allergy, 1992, Volume: 47, Issue:2 Pt 1

    Topics: Adolescent; Astemizole; Child; Conjunctivitis, Allergic; Cyproheptadine; Female; Histamine Antagonis

1992
Pharmacokinetics of astemizole in children.
    Rhinology. Supplement, 1992, Volume: 13

    Topics: Adolescent; Astemizole; Child; Conjunctivitis, Allergic; Female; Half-Life; Humans; Male; Pollen; Rh

1992
Onset and duration of the effects of three antihistamines in current use--astemizole, loratadine and terfenadine forte--studied during prolonged, controlled allergen challenges in volunteers.
    The Journal of international medical research, 1992, Volume: 20, Issue:5

    Topics: Adult; Allergens; Astemizole; Double-Blind Method; Female; Humans; Loratadine; Male; Nasal Mucosa; P

1992
Double-blind multicenter controlled clinical study comparing the efficacy of picumast dihydrochloride versus astemizole and placebo in patients with seasonal allergic rhinitis.
    Arzneimittel-Forschung, 1989, Volume: 39, Issue:10A

    Topics: Adult; Aged; Astemizole; Benzimidazoles; Coumarins; Double-Blind Method; Histamine H1 Antagonists; H

1989
[Total review of all results collected worldwide with astemizole (Hismanal)].
    Zeitschrift fur Hautkrankheiten, 1985, Volume: 60 Suppl 1

    Topics: Astemizole; Beclomethasone; Benzimidazoles; Bronchitis; Clinical Trials as Topic; Conjunctivitis; Do

1985
[Comparison of astemizole and terfenadine in maintenance therapy of hay fever].
    Zeitschrift fur Hautkrankheiten, 1985, Volume: 60 Suppl 1

    Topics: Adolescent; Adult; Astemizole; Benzhydryl Compounds; Benzimidazoles; Child; Clinical Trials as Topic

1985
[Hay fever therapy with 2 non-sedating antihistaminics].
    Zeitschrift fur Hautkrankheiten, 1985, Volume: 60 Suppl 1

    Topics: Arousal; Astemizole; Benzhydryl Compounds; Benzimidazoles; Clinical Trials as Topic; Conjunctivitis;

1985
Astemizole--a new, non-sedating antihistamine for hayfever.
    The Journal of otolaryngology, 1985, Volume: 14, Issue:2

    Topics: Adolescent; Adult; Astemizole; Benzimidazoles; Child; Clinical Trials as Topic; Double-Blind Method;

1985
Astemizole and terfenadine compared in hay fever.
    The Practitioner, 1986, Volume: 230, Issue:1411

    Topics: Adolescent; Adult; Astemizole; Benzhydryl Compounds; Benzimidazoles; Female; Histamine H1 Antagonist

1986
A comparison of oral astemizole with topical sodium cromoglycate in the treatment of hay fever.
    Current medical research and opinion, 1986, Volume: 10, Issue:3

    Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Analysis of Variance; Astemizole;

1986
Clinical profile of astemizole. A survey of 50 double-blind trials.
    Annals of allergy, 1987, Volume: 58, Issue:3

    Topics: Astemizole; Benzimidazoles; Clinical Trials as Topic; Conjunctivitis, Allergic; Double-Blind Method;

1987
Astemizole suspension in the maintenance treatment of paediatric hay fever: a comparison with terfenadine suspension.
    Pharmatherapeutica, 1986, Volume: 4, Issue:10

    Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Child; Female; Histamine H1 Antagonists; Humans; M

1986
[Astemizole and terfenadine: comparison of their therapeutic effect in pollen rhinitis].
    Revue medicale de la Suisse romande, 1987, Volume: 107, Issue:10

    Topics: Adolescent; Adult; Astemizole; Benzhydryl Compounds; Benzimidazoles; Clinical Trials as Topic; Doubl

1987
[A new H1-blocking antihistamine. Critical review of pharmacological and clinical studies].
    Minerva medica, 1988, Volume: 79, Issue:3

    Topics: Animals; Astemizole; Benzimidazoles; Clinical Trials as Topic; Conjunctivitis, Allergic; Dogs; Doubl

1988
Double-blind comparison of loratadine (SCH 29851), astemizole, and placebo in hay fever with special regard to onset of action.
    Annals of allergy, 1988, Volume: 61, Issue:6

    Topics: Adolescent; Adult; Astemizole; Benzimidazoles; Clinical Trials as Topic; Cyproheptadine; Dose-Respon

1988
Oral antihistamine or nasal steroid in hay fever: a double-blind double-dummy comparative study of once daily oral astemizole vs twice daily nasal beclomethasone dipropionate.
    Clinical allergy, 1986, Volume: 16, Issue:3

    Topics: Administration, Intranasal; Administration, Oral; Adult; Astemizole; Beclomethasone; Benzimidazoles;

1986
Efficacy of continuous treatment with astemizole (Hismanal) and terfenadine (Seldane) in ragweed pollen-induced rhinoconjunctivitis.
    The Journal of allergy and clinical immunology, 1988, Volume: 82, Issue:4

    Topics: Adult; Allergens; Astemizole; Benzhydryl Compounds; Benzimidazoles; Conjunctivitis, Allergic; Drug T

1988
Double-blind comparison of astemizole, terfenadine and placebo in hay fever with special regard to onset of action.
    The Journal of international medical research, 1985, Volume: 13, Issue:2

    Topics: Adult; Astemizole; Benzhydryl Compounds; Benzimidazoles; Double-Blind Method; Female; Humans; Male;

1985

Other Studies

18 other studies available for astemizole and Hay Fever

ArticleYear
Treatment of allergic rhinitis in infants and children: efficacy and safety of second-generation antihistamines and the leukotriene receptor antagonist montelukast.
    Drugs, 2009, Volume: 69, Issue:18

    Topics: Acetates; Administration, Oral; Adult; Anti-Allergic Agents; Anti-Asthmatic Agents; Astemizole; Ceti

2009
Practical therapeutics: the use of histamine receptor antagonists in contemporary times.
    East African medical journal, 1984, Volume: 61, Issue:7

    Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Child; Cimetidine; Conjunctivitis, Allergic; Hista

1984
Astemizole in the treatment of seasonal allergic rhinitis. A double- blind comparison with clemastine in patients sensitive to tree and grass pollen. Special reference to side effects registered in psychological tests.
    Acta oto-laryngologica. Supplementum, 1984, Volume: 409

    Topics: Adolescent; Adult; Aged; Astemizole; Auditory Perception; Benzimidazoles; Clemastine; Double-Blind M

1984
[Pityriasis-lichenoides-et-varioliformis-acuta-like drug exanthema caused by astemizole].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1993, Volume: 44, Issue:4

    Topics: Administration, Oral; Adult; Astemizole; Biopsy; Drug Eruptions; Humans; Male; Pityriasis Lichenoide

1993
Astemizole--induced paresthesiae.
    The Journal of the Association of Physicians of India, 1992, Volume: 40, Issue:9

    Topics: Adult; Astemizole; Female; Humans; Paresthesia; Rhinitis, Allergic, Seasonal

1992
Chronic rhinitis in children.
    International journal of pediatric otorhinolaryngology, 1992, Volume: 23, Issue:1

    Topics: Age Factors; Astemizole; Bacterial Infections; Carbolines; Child; Child, Preschool; Chronic Disease;

1992
Skin test inhibition by astemizole.
    Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 1992, Volume: 7, Issue:1

    Topics: Adult; Astemizole; Female; Humans; Male; Rhinitis, Allergic, Seasonal; Skin Tests

1992
[Inhibition of skin test by astemizole].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1992, Volume: 14, Issue:2

    Topics: Adult; Astemizole; Female; Humans; Intradermal Tests; Male; Rhinitis, Allergic, Seasonal

1992
Astemizole--another non-sedating antihistamine.
    The Medical letter on drugs and therapeutics, 1989, May-05, Volume: 31, Issue:791

    Topics: Astemizole; Benzimidazoles; Chronic Disease; Drug Administration Schedule; Histamine H1 Antagonists;

1989
A double-blind comparative trial of astemizole and terfenadine for the treatment of hay fever.
    Allergie et immunologie, 1989, Volume: 21, Issue:10

    Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Double-Blind Method; Histamine H1 Antagonists; Hum

1989
Comparative trial of two non-sedative H1 antihistamines, terfenadine and astemizole, for hay fever.
    Thorax, 1985, Volume: 40, Issue:5

    Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Histamine H1 Antagonists; Humans; Rhinitis, Allerg

1985
Comparative trial of two non-sedative H1 antihistamines, terfenadine and astemizole for hay fever.
    Thorax, 1985, Volume: 40, Issue:10

    Topics: Astemizole; Benzimidazoles; Histamine H1 Antagonists; Humans; Rhinitis, Allergic, Seasonal

1985
Treatment of allergic rhinitis with a new long-acting H1 receptor antagonist: astemizole.
    Annals of allergy, 1987, Volume: 58, Issue:1

    Topics: Adult; Appetite; Astemizole; Benzimidazoles; Chlorpheniramine; Drug Evaluation; Female; Histamine H1

1987
The development of a new antihistamine: astemizole.
    New England and regional allergy proceedings, 1985,Winter, Volume: 6, Issue:1

    Topics: Administration, Oral; Animals; Astemizole; Benzimidazoles; Conjunctivitis, Allergic; Histamine H1 An

1985
Efficacy of an oral antihistamine, astemizole, as compared to a nasal steroid spray in hay fever.
    Allergy, 1988, Volume: 43, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Astemizole; Beclomethasone; Benzimidazoles; Body Weight; Fe

1988
[General review of a non-sedative antihistaminic, astemizole (Hismanal), a H1 receptor antagonist].
    Allergie et immunologie, 1988, Volume: 20, Issue:5

    Topics: Astemizole; Asthma; Benzimidazoles; Histamine H1 Antagonists; Humans; Rhinitis, Allergic, Perennial;

1988
The use of antihistamines for the treatment of airway disease.
    Cutis, 1988, Oct-27, Volume: 42, Issue:4A

    Topics: Astemizole; Asthma; Benzhydryl Compounds; Benzimidazoles; Child; Chlorpheniramine; Double-Blind Meth

1988
Comparative trial of two non-sedative H1 antihistamines, terfenadine and astemizole, for hay fever.
    Thorax, 1986, Volume: 41, Issue:8

    Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Biological Availability; Humans; Rhinitis, Allergi

1986