astemizole has been researched along with Central Nervous System Origin Vertigo in 4 studies
Astemizole: Antihistamine drug now withdrawn from the market in many countries because of rare but potentially fatal side effects.
astemizole : A piperidine compound having a 2-(4-methoxyphenyl)ethyl group at the 1-position and an N-[(4-fluorobenzyl)benzimidazol-2-yl]amino group at the 4-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty-eight patients with chronic vertigo and positional and/or spontaneous nystagmus finished a double-blind study to determine the efficacy of astemizole on nystagmus and its symptoms." | 9.06 | Astemizole. Its use in the treatment of patients with chronic vertigo. ( Jackson, RT; Turner, JS, 1987) |
| "Thirty-eight patients with chronic vertigo and positional and/or spontaneous nystagmus finished a double-blind study to determine the efficacy of astemizole on nystagmus and its symptoms." | 5.06 | Astemizole. Its use in the treatment of patients with chronic vertigo. ( Jackson, RT; Turner, JS, 1987) |
| " Our results demonstrate that: i) 100 microliters ethanol induced robust behavioral changes, which was used in further experiments; ii) the clinically used antivertigo agent, astemizole, significantly reduced the rotational behavior in UL rats; iii) the more potent H3 antagonists, thioperamide and GT-2016, were more efficacious than betahistine, a mixed H3 antagonist and H1 agonist." | 3.70 | Histaminergic ligands attenuate barrel rotation in rats following unilateral labyrinthectomy. ( Brioni, JD; Hancock, AA; O'Neill, AB; Pan, JB; Sullivan, JP, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Turner, JS | 2 |
| Jackson, RT | 2 |
| Pan, JB | 1 |
| O'Neill, AB | 1 |
| Hancock, AA | 1 |
| Sullivan, JP | 1 |
| Brioni, JD | 1 |
| Wexler, DB | 1 |
1 trial available for astemizole and Central Nervous System Origin Vertigo
| Article | Year |
|---|---|
Astemizole. Its use in the treatment of patients with chronic vertigo.
Topics: Adult; Aged; Astemizole; Benzimidazoles; Chronic Disease; Consumer Behavior; Dizziness; Double-Blind | 1987 |
3 other studies available for astemizole and Central Nervous System Origin Vertigo
| Article | Year |
|---|---|
Astemizole: its use in patients with chronic vertigo and eng signs--a pilot study of a new drug.
Topics: Adult; Astemizole; Benzimidazoles; Chronic Disease; Electronystagmography; Female; Histamine H1 Anta | 1983 |
Histaminergic ligands attenuate barrel rotation in rats following unilateral labyrinthectomy.
Topics: Animals; Astemizole; Behavior, Animal; Ear, Inner; Ethanol; Imidazoles; Male; Rats; Rats, Long-Evans | 1998 |
Astemizole for treatment of chronic vertigo.
Topics: Astemizole; Benzimidazoles; Chronic Disease; Humans; Research Design; Vertigo | 1987 |