astemizole has been researched along with Bronchospasm in 3 studies
Astemizole: Antihistamine drug now withdrawn from the market in many countries because of rare but potentially fatal side effects.
astemizole : A piperidine compound having a 2-(4-methoxyphenyl)ethyl group at the 1-position and an N-[(4-fluorobenzyl)benzimidazol-2-yl]amino group at the 4-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The disparity between the activation of mast cells in the airways of patients with allergic asthma and the lack of efficacy of H1-antihistamines in asthma therapy has been difficult to reconcile." | 7.67 | Astemizole and other H1-antihistaminic drug treatment of asthma. ( Emanuel, MB; Holgate, ST; Howarth, PH, 1985) |
| " The aim of this study was to evaluate in vivo the influence of antihistamine in comparison to an anticholinergic drug on bronchospasm induced by inhalation of substance P (SP)." | 5.06 | Influence of antihistamine (astemizole) and anticholinergic drugs (ipratropium bromide) on bronchoconstriction induced by substance P. ( Crimi, N; Mistretta, A; Oliveri, R; Palermo, B; Palermo, F; Polosa, R; Vancheri, C, 1990) |
| "The disparity between the activation of mast cells in the airways of patients with allergic asthma and the lack of efficacy of H1-antihistamines in asthma therapy has been difficult to reconcile." | 3.67 | Astemizole and other H1-antihistaminic drug treatment of asthma. ( Emanuel, MB; Holgate, ST; Howarth, PH, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Crimi, N | 1 |
| Palermo, F | 1 |
| Oliveri, R | 1 |
| Palermo, B | 1 |
| Vancheri, C | 1 |
| Polosa, R | 1 |
| Mistretta, A | 1 |
| Holgate, ST | 1 |
| Emanuel, MB | 1 |
| Howarth, PH | 1 |
| Rafferty, P | 1 |
| Beasley, R | 1 |
| Southgate, P | 1 |
| Holgate, S | 1 |
2 trials available for astemizole and Bronchospasm
| Article | Year |
|---|---|
Influence of antihistamine (astemizole) and anticholinergic drugs (ipratropium bromide) on bronchoconstriction induced by substance P.
Topics: Administration, Inhalation; Adult; Astemizole; Atropine Derivatives; Benzimidazoles; Bronchial Spasm | 1990 |
The role of histamine in allergen and adenosine-induced bronchoconstriction.
Topics: Adenosine Monophosphate; Allergens; Astemizole; Benzhydryl Compounds; Benzimidazoles; Bronchial Prov | 1987 |
1 other study available for astemizole and Bronchospasm
| Article | Year |
|---|---|
Astemizole and other H1-antihistaminic drug treatment of asthma.
Topics: Astemizole; Asthma; Benzimidazoles; Bronchial Provocation Tests; Bronchial Spasm; Histamine; Histami | 1985 |