astemizole has been researched along with Anaphylaxis in 7 studies
Astemizole: Antihistamine drug now withdrawn from the market in many countries because of rare but potentially fatal side effects.
astemizole : A piperidine compound having a 2-(4-methoxyphenyl)ethyl group at the 1-position and an N-[(4-fluorobenzyl)benzimidazol-2-yl]amino group at the 4-position.
Anaphylaxis: An acute hypersensitivity reaction due to exposure to a previously encountered ANTIGEN. The reaction may include rapidly progressing URTICARIA, respiratory distress, vascular collapse, systemic SHOCK, and death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Effects of tecastemizole were assessed in a murine model of allergic lung inflammation, in passive cutaneous anaphylaxis (PCA) responses in guinea-pig skin and in in vitro assays measuring endothelial adhesion molecule expression and leucocyte-endothelial adhesion." | 3.74 | Effect of tecastemizole on pulmonary and cutaneous allergic inflammatory responses. ( Hefni, A; Lever, R; Moffatt, JD; Page, CP; Paul, W, 2007) |
| "In isolated perfused hearts, an anaphylactic reaction is characterized by arrhythmias, coronary constriction and severe impairment of ventricular contractile force." | 1.28 | Effects of histamine H1- and H2-receptor antagonists on cardiovascular function during systemic anaphylaxis in guinea pigs. ( Ahmad, Z; Baumann, G; Blömer, H; Felix, SB; Hashemi, T; Niemczyk, M; Ochsenfeld, G; Shirani, S, 1991) |
| "Astemizole is a very effective inhibitor of allergic reactions in rats and dogs." | 1.27 | [Pharmacology of astemizole (Hismanal) a non-sedating H1 antihistaminic]. ( Niemegeers, CJ, 1985) |
| " In numerous tests no evidence of central activity was found and toxicity studies have shown astemizole to be a very safe drug despite of its long duration of action." | 1.27 | The pharmacological profile of a specific, safe, effective and non-sedative anti-allergic, astemizole. ( Awouters, F; Janssen, PA; Niemegeers, CJ, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lever, R | 1 |
| Hefni, A | 1 |
| Moffatt, JD | 1 |
| Paul, W | 1 |
| Page, CP | 1 |
| Nichols, AW | 1 |
| Felix, SB | 1 |
| Baumann, G | 1 |
| Niemczyk, M | 1 |
| Hashemi, T | 1 |
| Ochsenfeld, G | 1 |
| Ahmad, Z | 1 |
| Shirani, S | 1 |
| Blömer, H | 1 |
| Nolan, JC | 1 |
| Stephens, DJ | 1 |
| Proakis, AG | 1 |
| Leonard, CA | 1 |
| Johnson, DN | 1 |
| Kilpatrick, BF | 1 |
| Foxwell, MH | 1 |
| Yanni, JM | 1 |
| Niemegeers, CJ | 2 |
| Awouters, F | 1 |
| Janssen, PA | 1 |
| Forck, G | 1 |
1 review available for astemizole and Anaphylaxis
| Article | Year |
|---|---|
Exercise-induced anaphylaxis and urticaria.
Topics: Anaphylaxis; Astemizole; Clemastine; Exercise; Humans; Terfenadine; Urticaria | 1992 |
6 other studies available for astemizole and Anaphylaxis
| Article | Year |
|---|---|
Effect of tecastemizole on pulmonary and cutaneous allergic inflammatory responses.
Topics: Anaphylaxis; Animals; Anti-Inflammatory Agents; Astemizole; Benzimidazoles; Cell Adhesion; Cell Adhe | 2007 |
Effects of histamine H1- and H2-receptor antagonists on cardiovascular function during systemic anaphylaxis in guinea pigs.
Topics: Anaphylaxis; Animals; Astemizole; Benzimidazoles; Blood Pressure; Cardiac Output; Cardiovascular Sys | 1991 |
Rocastine (AHR-11325), a rapid acting, nonsedating antihistamine.
Topics: Anaphylaxis; Animals; Astemizole; Azepines; Benzhydryl Compounds; Benzimidazoles; Brompheniramine; C | 1989 |
[Pharmacology of astemizole (Hismanal) a non-sedating H1 antihistaminic].
Topics: Administration, Oral; Anaphylaxis; Animals; Arousal; Astemizole; Benzimidazoles; Cerebellum; Dose-Re | 1985 |
The pharmacological profile of a specific, safe, effective and non-sedative anti-allergic, astemizole.
Topics: Anaphylaxis; Animals; Astemizole; Benzimidazoles; Histamine H1 Antagonists; Hypersensitivity; p-Meth | 1986 |
[Experimental studies with external and internal administration of antihistaminics in insect venom allergies].
Topics: Administration, Oral; Administration, Topical; Anaphylaxis; Astemizole; Bee Venoms; Benzimidazoles; | 1988 |