astemizole has been researched along with Alzheimer Disease in 5 studies
Astemizole: Antihistamine drug now withdrawn from the market in many countries because of rare but potentially fatal side effects.
astemizole : A piperidine compound having a 2-(4-methoxyphenyl)ethyl group at the 1-position and an N-[(4-fluorobenzyl)benzimidazol-2-yl]amino group at the 4-position.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Marco-Contelles, J | 1 |
| León, R | 1 |
| de los Ríos, C | 1 |
| Samadi, A | 1 |
| Bartolini, M | 1 |
| Andrisano, V | 1 |
| Huertas, O | 1 |
| Barril, X | 1 |
| Luque, FJ | 1 |
| Rodríguez-Franco, MI | 1 |
| López, B | 1 |
| López, MG | 1 |
| García, AG | 1 |
| Carreiras, Mdo C | 1 |
| Villarroya, M | 1 |
| Xu, YX | 1 |
| Wang, H | 2 |
| Li, XK | 1 |
| Dong, SN | 1 |
| Liu, WW | 1 |
| Gong, Q | 2 |
| Wang, TD | 1 |
| Tang, Y | 1 |
| Zhu, J | 2 |
| Li, J | 2 |
| Zhang, HY | 1 |
| Mao, F | 2 |
| Liu, W | 1 |
| Li, X | 1 |
| Xu, Y | 1 |
| Zhang, J | 1 |
| Wang, W | 1 |
| Qiu, X | 1 |
| Zhang, H | 1 |
| Hassan, M | 1 |
| Shahzadi, S | 1 |
| Yasir, M | 1 |
| Chun, W | 1 |
| Kloczkowski, A | 1 |
| Rojo, LE | 1 |
| Alzate-Morales, J | 1 |
| Saavedra, IN | 1 |
| Davies, P | 1 |
| Maccioni, RB | 1 |
5 other studies available for astemizole and Alzheimer Disease
| Article | Year |
|---|---|
Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Blood-Brain Barrier; Butyrylcholines | 2009 |
Discovery of novel propargylamine-modified 4-aminoalkyl imidazole substituted pyrimidinylthiourea derivatives as multifunctional agents for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; | 2018 |
Design, synthesis and evaluation of vilazodone-tacrine hybrids as multitarget-directed ligands against depression with cognitive impairment.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Blood-Brain Barrier; Butyrylcholinesterase; Cholin | 2018 |
Computational prognostic evaluation of Alzheimer's drugs from FDA-approved database through structural conformational dynamics and drug repositioning approaches.
Topics: Alzheimer Disease; Astemizole; Drug Repositioning; Humans; Molecular Docking Simulation; Molecular D | 2023 |
Selective interaction of lansoprazole and astemizole with tau polymers: potential new clinical use in diagnosis of Alzheimer's disease.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Alzheimer Disease; Astemizole; Brain; Chromatography, High | 2010 |