astemizole has been researched along with Allergic Conjunctivitis in 12 studies
Astemizole: Antihistamine drug now withdrawn from the market in many countries because of rare but potentially fatal side effects.
astemizole : A piperidine compound having a 2-(4-methoxyphenyl)ethyl group at the 1-position and an N-[(4-fluorobenzyl)benzimidazol-2-yl]amino group at the 4-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Two hundred and seven patients with active symptoms of allergic conjunctivitis were studied in a four-week multicentre double blind, double dummy, clinical trial comparing efficacy and safety of nedocromil sodium eye drops with oral astemizole, placebo, and the combined active treatments." | 9.07 | Nedocromil sodium and astemizole, alone or combined, in the treatment of seasonal allergic conjunctivitis. A multicentre double blind clinical trial. ( Bonini, S; Brovarone, FV; Miglior, M; Negrini, A; Pezzi, PP; Ruggieri, ML; Scullica, L; Secchi, AG; Vargiu, G, 1993) |
| "A 4 week open study was carried out to evaluate the efficacy and safety of astemizole in the treatment of allergic conjunctivitis 31 patients were included in the study." | 7.67 | [Evaluation of astemizole in allergic conjunctivitis]. ( Favennec, DF, 1989) |
| "Two hundred and seven patients with active symptoms of allergic conjunctivitis were studied in a four-week multicentre double blind, double dummy, clinical trial comparing efficacy and safety of nedocromil sodium eye drops with oral astemizole, placebo, and the combined active treatments." | 5.07 | Nedocromil sodium and astemizole, alone or combined, in the treatment of seasonal allergic conjunctivitis. A multicentre double blind clinical trial. ( Bonini, S; Brovarone, FV; Miglior, M; Negrini, A; Pezzi, PP; Ruggieri, ML; Scullica, L; Secchi, AG; Vargiu, G, 1993) |
| "Astemizole is a long-acting antihistamine that blocks the H1 receptors." | 3.76 | [A new H1-blocking antihistamine. Critical review of pharmacological and clinical studies]. ( Emmi, L; Rossi, O, 1988) |
| "A 4 week open study was carried out to evaluate the efficacy and safety of astemizole in the treatment of allergic conjunctivitis 31 patients were included in the study." | 3.67 | [Evaluation of astemizole in allergic conjunctivitis]. ( Favennec, DF, 1989) |
| "Current pathogenetic and symptomatological knowledge of allergic conjunctivitis and its treatment with a recently synthesised antihistaminic molecule, Astemizole, is reported." | 3.67 | [Clinical experimentation with a new antihistaminic molecule in allergic conjunctivitis]. ( Hesse, A; Reggiardo, F; Rivara, A; Satragno, L, 1988) |
| " Study III (elimination half-life [t1/2 beta]): In 10 of the children from study II, t1/2 beta for astemizole plus DMA could be calculated (two samples) and was 10." | 2.67 | Pharmacokinetics of astemizole in children. ( Andlin-Sobocki, P; Blychert, LO; Möller, C, 1992) |
| "Triamcinolone is a commonly used synthetic corticosteroid that has recently been tested in a large clinical trial for chronic obstructive pulmonary disease and shown to have some benefits." | 2.41 | Triamcinolone: new and old indications. ( Doggrell, SA, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (58.33) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Obel, AO | 1 |
| Miglior, M | 1 |
| Scullica, L | 1 |
| Secchi, AG | 1 |
| Negrini, A | 1 |
| Pezzi, PP | 1 |
| Brovarone, FV | 1 |
| Bonini, S | 1 |
| Ruggieri, ML | 1 |
| Vargiu, G | 1 |
| Doggrell, SA | 1 |
| Boner, AL | 1 |
| Richelli, C | 1 |
| Castellani, C | 1 |
| Marchesi, E | 1 |
| Andreoli, A | 1 |
| Möller, C | 1 |
| Andlin-Sobocki, P | 1 |
| Blychert, LO | 1 |
| Wood, SF | 1 |
| Favennec, DF | 1 |
| Vanden Bussche, G | 1 |
| Emanuel, MB | 1 |
| Rombaut, N | 1 |
| Ray, JA | 1 |
| Emmi, L | 1 |
| Rossi, O | 1 |
| Hesse, A | 1 |
| Reggiardo, F | 1 |
| Satragno, L | 1 |
| Rivara, A | 1 |
| Juniper, EF | 1 |
| White, J | 1 |
| Dolovich, J | 1 |
3 reviews available for astemizole and Allergic Conjunctivitis
| Article | Year |
|---|---|
Triamcinolone: new and old indications.
Topics: Administration, Intranasal; Adult; Aerosols; Androstadienes; Anti-Inflammatory Agents; Arthritis, Rh | 2001 |
Clinical experience with non-sedating antihistamines in paediatric allergic rhinitis.
Topics: Adolescent; Astemizole; Asthma; Child; Child, Preschool; Chlorpheniramine; Clinical Trials as Topic; | 1992 |
[A new H1-blocking antihistamine. Critical review of pharmacological and clinical studies].
Topics: Animals; Astemizole; Benzimidazoles; Clinical Trials as Topic; Conjunctivitis, Allergic; Dogs; Doubl | 1988 |
6 trials available for astemizole and Allergic Conjunctivitis
| Article | Year |
|---|---|
Nedocromil sodium and astemizole, alone or combined, in the treatment of seasonal allergic conjunctivitis. A multicentre double blind clinical trial.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Astemizole; Child; Conjunctivitis, | 1993 |
Comparison of the effects of loratadine and astemizole in the treatment of children with seasonal allergic rhinoconjunctivitis.
Topics: Adolescent; Astemizole; Child; Conjunctivitis, Allergic; Cyproheptadine; Female; Histamine Antagonis | 1992 |
Pharmacokinetics of astemizole in children.
Topics: Adolescent; Astemizole; Child; Conjunctivitis, Allergic; Female; Half-Life; Humans; Male; Pollen; Rh | 1992 |
Clinical profile of astemizole. A survey of 50 double-blind trials.
Topics: Astemizole; Benzimidazoles; Clinical Trials as Topic; Conjunctivitis, Allergic; Double-Blind Method; | 1987 |
[A new H1-blocking antihistamine. Critical review of pharmacological and clinical studies].
Topics: Animals; Astemizole; Benzimidazoles; Clinical Trials as Topic; Conjunctivitis, Allergic; Dogs; Doubl | 1988 |
Efficacy of continuous treatment with astemizole (Hismanal) and terfenadine (Seldane) in ragweed pollen-induced rhinoconjunctivitis.
Topics: Adult; Allergens; Astemizole; Benzhydryl Compounds; Benzimidazoles; Conjunctivitis, Allergic; Drug T | 1988 |
4 other studies available for astemizole and Allergic Conjunctivitis
| Article | Year |
|---|---|
Practical therapeutics: the use of histamine receptor antagonists in contemporary times.
Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Child; Cimetidine; Conjunctivitis, Allergic; Hista | 1984 |
[Evaluation of astemizole in allergic conjunctivitis].
Topics: Adult; Astemizole; Benzimidazoles; Conjunctivitis, Allergic; Female; Histamine H1 Antagonists; Human | 1989 |
The development of a new antihistamine: astemizole.
Topics: Administration, Oral; Animals; Astemizole; Benzimidazoles; Conjunctivitis, Allergic; Histamine H1 An | 1985 |
[Clinical experimentation with a new antihistaminic molecule in allergic conjunctivitis].
Topics: Adolescent; Adult; Astemizole; Benzimidazoles; Child; Conjunctivitis, Allergic; Drug Evaluation; Fem | 1988 |