astemizole has been researched along with A-V Dissociation in 4 studies
Astemizole: Antihistamine drug now withdrawn from the market in many countries because of rare but potentially fatal side effects.
astemizole : A piperidine compound having a 2-(4-methoxyphenyl)ethyl group at the 1-position and an N-[(4-fluorobenzyl)benzimidazol-2-yl]amino group at the 4-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In order to study the effects of anesthetic agents on the inducibility of TdP, arrhythmias were induced by programmed electrical stimulation (PES) before and after cumulative intravenous administration of quinidine under anesthesia with sodium pentobarbital, halothane, or isoflurane." | 7.71 | Acute canine model for drug-induced Torsades de Pointes in drug safety evaluation-influences of anesthesia and validation with quinidine and astemizole. ( Imai, R; Tamura, T; Yamamoto, K; Yamamoto, M, 2001) |
| " In order to study the effects of anesthetic agents on the inducibility of TdP, arrhythmias were induced by programmed electrical stimulation (PES) before and after cumulative intravenous administration of quinidine under anesthesia with sodium pentobarbital, halothane, or isoflurane." | 3.71 | Acute canine model for drug-induced Torsades de Pointes in drug safety evaluation-influences of anesthesia and validation with quinidine and astemizole. ( Imai, R; Tamura, T; Yamamoto, K; Yamamoto, M, 2001) |
| " We report a case in which a deliberate overdose of astemizole was associated with Mobitz type two heart block and prolongation of the QT interval, causing the so-called torsade-de-pointes ventricular tachycardia." | 3.68 | Astemizole-induced ventricular arrhythmias: an unexpected cause of convulsions. ( Clark, A; Love, H, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ohmura, T | 1 |
| Chachin, M | 1 |
| Tarui, S | 1 |
| Nagakura, A | 1 |
| Igarashi, T | 1 |
| Ikeda, H | 1 |
| Ikegami, K | 1 |
| Kitagawa, H | 1 |
| Uchida, S | 1 |
| Yamamoto, K | 1 |
| Tamura, T | 1 |
| Imai, R | 1 |
| Yamamoto, M | 1 |
| Wiley, JF | 1 |
| Gelber, ML | 1 |
| Henretig, FM | 1 |
| Wiley, CC | 1 |
| Sandhu, S | 1 |
| Loiselle, J | 1 |
| Clark, A | 1 |
| Love, H | 1 |
4 other studies available for astemizole and A-V Dissociation
| Article | Year |
|---|---|
Effects of terfenadine, astemizole and epinastine on electrocardiogram in conscious cynomolgus monkeys.
Topics: Animals; Arrhythmias, Cardiac; Astemizole; Dibenzazepines; Electrocardiography; Heart Block; Histami | 1999 |
Acute canine model for drug-induced Torsades de Pointes in drug safety evaluation-influences of anesthesia and validation with quinidine and astemizole.
Topics: Acute Disease; Anesthesia; Anesthetics, Inhalation; Animals; Astemizole; Atrioventricular Node; Cath | 2001 |
Cardiotoxic effects of astemizole overdose in children.
Topics: Arrhythmias, Cardiac; Astemizole; Child; Child, Preschool; Electrocardiography; Heart Block; Humans; | 1992 |
Astemizole-induced ventricular arrhythmias: an unexpected cause of convulsions.
Topics: Adolescent; Astemizole; Drug Overdose; Electrocardiography; Female; Heart Block; Humans; Seizures; T | 1991 |