aspirin has been researched along with Transposition of Great Vessels in 5 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Transposition of Great Vessels: A congenital cardiovascular malformation in which the AORTA arises entirely from the RIGHT VENTRICLE, and the PULMONARY ARTERY arises from the LEFT VENTRICLE. Consequently, the pulmonary and the systemic circulations are parallel and not sequential, so that the venous return from the peripheral circulation is re-circulated by the right ventricle via aorta to the systemic circulation without being oxygenated in the lungs. This is a potentially lethal form of heart disease in newborns and infants.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It has been hypothesized that the ingestion of aspirin by women during pregnancy increases their infants' risk of certain congenital heart defects." | 7.67 | The relation of aspirin use during the first trimester of pregnancy to congenital cardiac defects. ( Mitchell, AA; Shapiro, S; Werler, MM, 1989) |
| "It has been hypothesized that the ingestion of aspirin by women during pregnancy increases their infants' risk of certain congenital heart defects." | 3.67 | The relation of aspirin use during the first trimester of pregnancy to congenital cardiac defects. ( Mitchell, AA; Shapiro, S; Werler, MM, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Morrison, ML | 1 |
| Lockhart, CJ | 1 |
| Grant, B | 1 |
| Soós, J | 1 |
| Várkonyi, P | 1 |
| Hartyánszky, I | 1 |
| Szabolcs, J | 1 |
| Fekete-Farkas, P | 1 |
| Lozsádi, K | 1 |
| Werler, MM | 1 |
| Mitchell, AA | 1 |
| Shapiro, S | 1 |
| Kozinn, PJ | 1 |
| Lynfield, J | 1 |
| Seelig, MS | 1 |
| Takacs, E | 1 |
| Warkany, J | 1 |
5 other studies available for aspirin and Transposition of Great Vessels
| Article | Year |
|---|---|
Contemporary imaging following atrial redirection surgery for transposition of the great arteries.
Topics: Adult; Arterial Switch Operation; Aspirin; Echocardiography, Doppler, Color; Fibrinolytic Agents; Hu | 2016 |
[Possibility of closure of the patent dutus arteriosus by drug therapy in the management of congenital defects in the newborn infant (preliminary report)].
Topics: Aspirin; Ductus Arteriosus, Patent; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male | 1978 |
The relation of aspirin use during the first trimester of pregnancy to congenital cardiac defects.
Topics: Abnormalities, Drug-Induced; Aortic Coarctation; Aortic Valve Stenosis; Aspirin; Case-Control Studie | 1989 |
Successful treatment of systemic candidiasis following cardiac surgery.
Topics: Administration, Oral; Anti-Bacterial Agents; Antibodies; Antifungal Agents; Aspirin; Candida albican | 1974 |
Experimental production of congenital cardiovascular malformations in rats by salicylate poisoning.
Topics: Abnormalities, Drug-Induced; Animals; Aorta; Aspirin; Dextrocardia; Female; Fetal Heart; Gestational | 1968 |