aspirin has been researched along with Transfusion Reaction in 20 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Transfusion Reaction: Complications of BLOOD TRANSFUSION. Included adverse reactions are common allergic and febrile reactions; hemolytic (delayed and acute) reactions; and other non-hemolytic adverse reactions such as infections and adverse immune reactions related to immunocompatibility.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Aspirin has been found to improve outcomes in an animal model of transfusion-related acute lung injury." | 7.78 | The effect of aspirin in transfusion-related acute lung injury in critically ill patients. ( Binnenkade, JM; Juffermans, NP; Tuinman, PR; Vlaar, AP, 2012) |
| "Aspirin (ASA) treatment significantly reduced lung platelet sequestration and activation, NPA formation, and lung injury." | 5.40 | Aspirin-triggered 15-epi-lipoxin A4 regulates neutrophil-platelet aggregation and attenuates acute lung injury in mice. ( Bins, A; Headley, M; Krummel, MF; Looney, MR; Mallavia, B; Ortiz-Muñoz, G, 2014) |
| "Aspirin has been found to improve outcomes in an animal model of transfusion-related acute lung injury." | 3.78 | The effect of aspirin in transfusion-related acute lung injury in critically ill patients. ( Binnenkade, JM; Juffermans, NP; Tuinman, PR; Vlaar, AP, 2012) |
| "We performed a retrospective cohort study of 1677 patients undergoing coronary artery bypass surgery to determine the relationship of the preoperative use of aspirin plus clopidogrel vs aspirin alone to the 30-day incidence of postoperative surgical site infection and bacteremia." | 3.75 | Aspirin plus clopidogrel and risk of infection after coronary artery bypass surgery. ( Alejo, D; Baumgartner, WA; Blasco-Colmenares, E; Conte, JV; Faraday, N; Guallar, E; Pastor-Barriuso, R; Perl, TM; Sharrett, AR, 2009) |
| "The incidence of symptomatic deep vein thrombosis and pulmonary embolism was evaluated." | 1.43 | Tranexamic Acid Can Be Administered to Arthroplasty Patients Who Receive Aspirin for Venous Thromboembolic Prophylaxis. ( Chen, AF; Heller, S; Parvizi, J; Secrist, E; Shahi, A, 2016) |
| "An incidence as high as 60% of silent cerebral infarcts (SCI) has been demonstrated by brain Magnetic Resonance Imaging (MRI) studies in beta thalassemia intermedia (TI)." | 1.43 | High incidence of silent cerebral infarcts in adult patients with beta thalassemia major. ( Cohen, M; Inbar, E; Pazgal, I; Shpilberg, O; Stark, P, 2016) |
| "Aspirin (ASA) treatment significantly reduced lung platelet sequestration and activation, NPA formation, and lung injury." | 1.40 | Aspirin-triggered 15-epi-lipoxin A4 regulates neutrophil-platelet aggregation and attenuates acute lung injury in mice. ( Bins, A; Headley, M; Krummel, MF; Looney, MR; Mallavia, B; Ortiz-Muñoz, G, 2014) |
| " Desensitization, when essential, may be achieved for most drugs with graduated dosage schedules and maintained through continued administration of the drug." | 1.27 | Management of adverse drug reactions. ( Pennoyer, DS; Sheffer, AL, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (55.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 2 (10.00) | 29.6817 |
| 2010's | 6 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ortiz-Muñoz, G | 1 |
| Mallavia, B | 1 |
| Bins, A | 1 |
| Headley, M | 1 |
| Krummel, MF | 1 |
| Looney, MR | 3 |
| Heller, S | 1 |
| Secrist, E | 1 |
| Shahi, A | 1 |
| Chen, AF | 1 |
| Parvizi, J | 1 |
| Pazgal, I | 1 |
| Inbar, E | 1 |
| Cohen, M | 1 |
| Shpilberg, O | 1 |
| Stark, P | 1 |
| Blasco-Colmenares, E | 1 |
| Perl, TM | 1 |
| Guallar, E | 1 |
| Baumgartner, WA | 1 |
| Conte, JV | 1 |
| Alejo, D | 1 |
| Pastor-Barriuso, R | 1 |
| Sharrett, AR | 1 |
| Faraday, N | 1 |
| Tuinman, PR | 1 |
| Vlaar, AP | 1 |
| Binnenkade, JM | 1 |
| Juffermans, NP | 1 |
| Caudrillier, A | 2 |
| Kessenbrock, K | 1 |
| Gilliss, BM | 1 |
| Nguyen, JX | 1 |
| Marques, MB | 1 |
| Monestier, M | 1 |
| Toy, P | 1 |
| Werb, Z | 1 |
| Sheffer, AL | 1 |
| Pennoyer, DS | 1 |
| Slichter, SJ | 1 |
| De Vita, C | 1 |
| Baron, JF | 1 |
| Arnoldo, BD | 1 |
| Minei, JP | 1 |
| Cabanac, M | 1 |
| Ekert, H | 1 |
| Waters, KD | 1 |
| Davies, DW | 1 |
| Steward, DJ | 1 |
| Becker, GA | 1 |
| Aster, RH | 1 |
| Bergentz, SE | 2 |
| Sidhu, AK | 1 |
| Bhakoo, ON | 1 |
| Jolly, JG | 1 |
| Walia, BN | 1 |
| Hampton, JW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase II, Randomized, Single-Blind, Controlled Clinical Trial to Evaluate the Efficacy and Safety of Hemolink[Tm] (o-Raffinose Cross-Linked Human Hemoglobin) in Subjects Undergoing Primary Coronary Artery Bypass Grafting Surgery[NCT00038454] | Phase 2/Phase 3 | 180 participants | Interventional | Suspended | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for aspirin and Transfusion Reaction
| Article | Year |
|---|---|
Platelet-neutrophil interactions as a target for prevention and treatment of transfusion-related acute lung injury.
Topics: Acute Lung Injury; Animals; Aspirin; Blood Platelets; Blood Transfusion; Drug Delivery Systems; Hemo | 2012 |
Identification & management of defects in platelet hemostasis in massively transfused patients.
Topics: Animals; Aspirin; Bleeding Time; Blood Preservation; Blood Transfusion; Cardiopulmonary Bypass; Cell | 1982 |
Haemoglobin therapy in clinical practice: use and characteristics of DCLHb.
Topics: Aspirin; Forecasting; Hemoglobins; Humans; Perioperative Care; Transfusion Reaction | 1998 |
Potential of hemoglobin-based oxygen carriers in trauma patients.
Topics: Aspirin; Blood Substitutes; Clinical Trials as Topic; Fluorocarbons; Hemoglobins; Humans; Oxygen; Ra | 2001 |
Platelet transfusion therapy.
Topics: Anemia, Aplastic; Antigens; Aspirin; Blood Banks; Blood Group Antigens; Blood Platelet Disorders; Bl | 1972 |
Septic shock and disturbances in coagulation.
Topics: Acidosis; Acute Kidney Injury; Aminocaproates; Aspirin; Blood Coagulation Disorders; Blood Coagulati | 1974 |
14 other studies available for aspirin and Transfusion Reaction
| Article | Year |
|---|---|
Aspirin-triggered 15-epi-lipoxin A4 regulates neutrophil-platelet aggregation and attenuates acute lung injury in mice.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Bronc | 2014 |
Tranexamic Acid Can Be Administered to Arthroplasty Patients Who Receive Aspirin for Venous Thromboembolic Prophylaxis.
Topics: Aged; Antifibrinolytic Agents; Arthroplasty; Aspirin; Blood Loss, Surgical; Cohort Studies; Female; | 2016 |
High incidence of silent cerebral infarcts in adult patients with beta thalassemia major.
Topics: Adult; Aspirin; beta-Thalassemia; Cerebral Infarction; Cerebrum; Female; Ferritins; Fibrinolytic Age | 2016 |
Aspirin plus clopidogrel and risk of infection after coronary artery bypass surgery.
Topics: Aged; Aspirin; Bacteremia; Blood Transfusion; Clopidogrel; Cohort Studies; Coronary Artery Bypass; D | 2009 |
The effect of aspirin in transfusion-related acute lung injury in critically ill patients.
Topics: Acute Lung Injury; Adult; Aged; APACHE; Aspirin; Case-Control Studies; Cohort Studies; Critical Care | 2012 |
Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury.
Topics: Acute Lung Injury; Animals; Antibodies, Monoclonal; Aspirin; Blood Platelets; Cell Aggregation; Cell | 2012 |
Management of adverse drug reactions.
Topics: Anaphylaxis; Antineoplastic Agents; Aspirin; Bronchial Spasm; Drug Hypersensitivity; Drug-Related Si | 1984 |
[Problems of the operated patient and suggestions for their treatment].
Topics: Angina Pectoris; Anti-Arrhythmia Agents; Anticoagulants; Anxiety Disorders; Arrhythmias, Cardiac; As | 1982 |
[Fever and evolution].
Topics: Animals; Aspirin; Bacterial Infections; Behavior, Animal; Biological Evolution; Birds; Body Temperat | 1978 |
Hematologic emergencies in children.
Topics: Acute Disease; Acute Kidney Injury; Adolescent; Anemia, Aplastic; Anemia, Hemolytic, Autoimmune; Asp | 1978 |
Unexpected excessive bleeding during operation: role of acetyl salycilic acid.
Topics: Adolescent; Aspirin; Blood Platelets; Fibrinolysis; Hemorrhage; Hemostasis; Humans; Infant; Platelet | 1977 |
Blood transfusion reactions in children.
Topics: Aspirin; Benzyl Compounds; Child; Child, Preschool; Ethylenediamines; Fever; Furosemide; Heart Failu | 1972 |
[Proceedings: Bleeding problems due to platelet disorders (author's transl)].
Topics: Aspirin; Blood Cell Count; Blood Platelet Disorders; Blood Platelets; Humans; Kidney Failure, Chroni | 1973 |
Bleeding disorders during surgery.
Topics: Adrenal Cortex Hormones; Aspirin; Blood Coagulation Disorders; Blood Coagulation Factors; Blood Coag | 1974 |