aspirin has been researched along with Thrombopenia in 228 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thrombocytopenia, though uncommon, was associated with orbofiban use and an increased risk of bleeding, but also death and MI." | 9.12 | Drug-induced thrombocytopenia and thrombosis: evidence from patients receiving an oral glycoprotein IIb/IIIa inhibitor in the Orbofiban in Patients with Unstable coronary Syndromes- (OPUS-TIMI 16) trial. ( Aster, RH; Brassard, J; Braunwald, E; Cannon, CP; Charlesworth, A; Cooper, R; McCabe, CH; Scirica, BM; Skene, AM, 2006) |
| "The patient developed acute profound thrombocytopenia following eptifibatide administration." | 8.12 | Eptifibatide-induced acute profound thrombocytopenia: A case report. ( Al Kindi, DI; Al-Mashdali, A; Alamin, MA; Elshaikh, EA; Othman, F, 2022) |
| "In this single-center analysis of patients who received aspirin within 24 hours of CABG, postoperative thrombocytopenia was not associated with an increase in bleeding." | 8.12 | Impact of Thrombocytopenia on Postoperative Bleeding Incidence in Patients Receiving Aspirin Following Coronary Artery Bypass Grafting. ( Dobbins, KF; Henderson, JB; Hollis, IB; Rodino, AM; Rubin, DT, 2022) |
| " The risk and benefit of aspirin are not known in thrombocytopenic cancer patients experiencing acute myocardial infarction (AMI)." | 7.85 | Aspirin Is Associated with Improved Survival in Severely Thrombocytopenic Cancer Patients with Acute Myocardial Infarction. ( Feher, A; Gupta, D; Kampaktsis, PN; Parameswaran, R; Stein, EM; Steingart, R, 2017) |
| "Patients with cancer who have thrombocytopenia may experience acute coronary syndromes (ACS), and the use of aspirin (ASA) poses an increased risk of bleeding." | 7.74 | Impact of aspirin therapy in cancer patients with thrombocytopenia and acute coronary syndromes. ( Botz, G; Champion, JC; Durand, JB; Hirch-Ginsburg, C; Lakkis, N; Lenihan, DJ; Sarkiss, MG; Shaw, AD; Swafford, J; Warneke, CL; Yusuf, SW, 2007) |
| "Platelet adenosine diphosphate (ADP) receptors may play a role in potentiating platelet activation induced by IgG from patients with immune heparin-induced thrombocytopenia (HIT), as shown by previous studies using the ADP receptor antagonists AR-C66096 and ticlopidine." | 7.73 | Immune heparin-induced thrombocytopenia can occur in patients receiving clopidogrel and aspirin. ( Greinacher, A; Raschke, R; Rosenblood, GS; Schmidt, CO; Selleng, K; Selleng, S; Warkentin, TE, 2005) |
| "The first case of haemolytic anaemia with thrombocytopenia and acute renal failure induced by ingestion of aspirin in a 22-year old woman is reported." | 7.67 | [Immunoallergic hemolytic anemia, thrombopenia and acute renal failure induced by aspirin]. ( Debray, J; Habibi, B; Hubert, D; Krulik, M, 1984) |
| "We describe 2 patients with primary antiphospholipid syndrome in whom thrombocytopenia, which had not responded to high dose prednisone treatment, was promptly corrected after they started taking small doses (100 mg/day) of aspirin." | 7.67 | Correction of thrombocytopenia with small dose aspirin in the primary antiphospholipid syndrome. ( Alarcón-Segovia, D; Sánchez-Guerrero, J, 1989) |
| "Three children with the hemolytic-uremic syndrome were treated with heparin, aspirin, and dipyridamole." | 7.65 | Preliminary report: treatment of the hemolytic-uremic syndrome with aspirin and dipyridamole. ( Arenson, EB; August, CS, 1975) |
| "Profound thrombocytopenia has reportedly been an issue with abciximab, but not with tirofiban." | 5.32 | Repetitive profound thrombocytopenia after treatment with tirofiban: a case report. ( Erkoc, R; Eryonucu, B; Tuncer, M, 2004) |
| "To determine whether low molecular weight heparin (LMWH) plus low-dose aspirin (LDA) is comparable in efficacy and safety to unfractionated heparin (UFH) plus LDA in the management of pregnant women with a history of recurrent spontaneous abortion secondary to antiphospholipid syndrome (APS)." | 5.15 | Enoxaparin versus unfractionated heparin in the management of recurrent abortion secondary to antiphospholipid syndrome. ( Abdou, AM; Fouda, IM; Fouda, UM; Ramadan, DI; Sayed, AM; Zaki, MM, 2011) |
| "Any bleeding and TIMI major bleeding complications increase in patients aged ≥75 years treated with clopidogrel in addition to aspirin." | 5.15 | Safety of clopidogrel in older patients: a nonrandomized, parallel-group, controlled, two-centre study. ( Aydogdu, S; Balbay, Y; Cagirci, G; Cay, S; Demir, AD; Erbay, AR; Maden, O; Sen, N, 2011) |
| "Thrombocytopenia, though uncommon, was associated with orbofiban use and an increased risk of bleeding, but also death and MI." | 5.12 | Drug-induced thrombocytopenia and thrombosis: evidence from patients receiving an oral glycoprotein IIb/IIIa inhibitor in the Orbofiban in Patients with Unstable coronary Syndromes- (OPUS-TIMI 16) trial. ( Aster, RH; Brassard, J; Braunwald, E; Cannon, CP; Charlesworth, A; Cooper, R; McCabe, CH; Scirica, BM; Skene, AM, 2006) |
| "This was a prospective observation of pregnancy outcomes among 462 women with pregestational diabetes mellitus (White classes B-F) and singleton pregnancies who were enrolled in a multicenter trial to compare low-dose aspirin with placebo for preeclampsia prevention." | 5.09 | Risks of preeclampsia and adverse neonatal outcomes among women with pregestational diabetes mellitus. National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units. ( Caritis, S; Dombrowski, M; Hauth, J; Klebanoff, M; Landon, M; Lindheimer, M; MacPherson, C; McNellis, D; Meis, P; Miodovnik, M; Paul, R; Roberts, J; Sibai, BM; Thurnau, G; VanDorsten, JP, 2000) |
| "Compared with aspirin, clopidogrel reduced the combined risk of ischaemic stroke, myocardial infarction or vascular death by 8." | 5.09 | Comparative safety and tolerability of clopidogrel and aspirin: results from CAPRIE. CAPRIE Steering Committee and Investigators. Clopidogrel versus aspirin in patients at risk of ischaemic events. ( Boissel, JP; Gent, M; Harker, LA; Pilgrim, AJ, 1999) |
| " We present a case of profound thrombocytopenia due to administration of a glycoprotein IIb/IIIa receptor antagonist, eptifibatide, after percutaneous coronary intervention for an inferior ST-elevation myocardial infarction." | 4.91 | Thrombocytopenia in acute coronary syndromes: etiologies and proposed management. ( Bainey, KR; Ferguson, C; Sharma, A, 2015) |
| " Clinical trials have demonstrated that patients with antiphospholipid antibodies and venous thromboembolism should be treated with vitamin K antagonists (warfarin); that ischemic stroke may be treated with aspirin or warfarin; and that women with recurrent pregnancy loss should receive prophylactic-dose heparin and aspirin." | 4.85 | Antiphospholipid antibody syndrome. ( Lim, W, 2009) |
| " It seems effective for the prevention of recurrent pregnancy losses when conventional strategies using subcutaneous heparin and low-dose aspirin have failed." | 4.80 | [Therapeutic use of intravenous immunoglobulins in the antiphospholipid syndrome]. ( Lê Thi Huong, D; Piette, JC; Wechsler, B, 2000) |
| "In this single-center analysis of patients who received aspirin within 24 hours of CABG, postoperative thrombocytopenia was not associated with an increase in bleeding." | 4.12 | Impact of Thrombocytopenia on Postoperative Bleeding Incidence in Patients Receiving Aspirin Following Coronary Artery Bypass Grafting. ( Dobbins, KF; Henderson, JB; Hollis, IB; Rodino, AM; Rubin, DT, 2022) |
| "The patient developed acute profound thrombocytopenia following eptifibatide administration." | 4.12 | Eptifibatide-induced acute profound thrombocytopenia: A case report. ( Al Kindi, DI; Al-Mashdali, A; Alamin, MA; Elshaikh, EA; Othman, F, 2022) |
| " Risk factors for pregnancy complications, including premature delivery before 34 gestational weeks, hypertensive disorders of pregnancy, thrombocytopenia, and light-for-date neonate, were evaluated in 51 women who received low dose aspirin (LDA) plus unfractionated heparin (UFH) and delivered after 24 GW." | 3.85 | Factors associated with adverse pregnancy outcomes in women with antiphospholipid syndrome: A multicenter study. ( Deguchi, M; Fujita, D; Makino, S; Miki, A; Morikawa, M; Murashima, A; Sugiura-Ogasawara, M; Yamada, H, 2017) |
| " The risk and benefit of aspirin are not known in thrombocytopenic cancer patients experiencing acute myocardial infarction (AMI)." | 3.85 | Aspirin Is Associated with Improved Survival in Severely Thrombocytopenic Cancer Patients with Acute Myocardial Infarction. ( Feher, A; Gupta, D; Kampaktsis, PN; Parameswaran, R; Stein, EM; Steingart, R, 2017) |
| " She was started on 100 mg of aspirin, 20 mg of prednisolone and 20 mg of subcutaneous low-molecular-weight heparin daily for her fourth pregnancy." | 3.83 | Repeated failed non-invasive prenatal testing in a woman with immune thrombocytopenia and antiphospholipid syndrome: lessons learnt. ( Hui, CY; Tan, EL; Tan, LK; Tan, WC, 2016) |
| " Case-control analysis showed that comorbidities of hypertension, purpura and thrombocytopenia, and the use of aspirin were significantly associated with the risk of NTSCH." | 3.81 | Incidence of Non-Traumatic Subconjunctival Hemorrhage in a Nationwide Study in Taiwan from 2000 to 2011. ( Chao, SC; Hu, DN; Jonas, JB; Kuan, PT; Lin, CY; Mou, CH; Nien, CW; Sung, FC, 2015) |
| " A 35-year-old lady with ES taking aspirin with clopidogrel for thrombo-prophylaxis presented with massive epistaxis." | 3.77 | Massive epistaxis in a patient with Eisenmenger syndrome: illustrating the clot-versus-bleed conundrum. ( Liu, A; Pusalkar, P; Saman, H, 2011) |
| "Previous studies predate the current practice of treating acute coronary syndrome patients with heparin and aspirin plus thienopyridines and glycoprotein IIb/IIIa receptor antagonists such that data are unavailable to determine if their co-administration worsens IABP-associated thrombocytopenia." | 3.74 | Thrombocytopenia in patients treated with heparin, combination antiplatelet therapy, and intra-aortic balloon pump counterpulsation. ( Bream-Rouwenhorst, HR; Hobbs, RA; Horwitz, PA, 2008) |
| "Patients with cancer who have thrombocytopenia may experience acute coronary syndromes (ACS), and the use of aspirin (ASA) poses an increased risk of bleeding." | 3.74 | Impact of aspirin therapy in cancer patients with thrombocytopenia and acute coronary syndromes. ( Botz, G; Champion, JC; Durand, JB; Hirch-Ginsburg, C; Lakkis, N; Lenihan, DJ; Sarkiss, MG; Shaw, AD; Swafford, J; Warneke, CL; Yusuf, SW, 2007) |
| "Platelet adenosine diphosphate (ADP) receptors may play a role in potentiating platelet activation induced by IgG from patients with immune heparin-induced thrombocytopenia (HIT), as shown by previous studies using the ADP receptor antagonists AR-C66096 and ticlopidine." | 3.73 | Immune heparin-induced thrombocytopenia can occur in patients receiving clopidogrel and aspirin. ( Greinacher, A; Raschke, R; Rosenblood, GS; Schmidt, CO; Selleng, K; Selleng, S; Warkentin, TE, 2005) |
| " In a mouse model of hypoxia-induced retinal angiogenesis, the situation of thrombocytopenia as well as inhibition of platelet aggregation by a highly specific alphaIIbbeta3-integrin antagonist or acetyl salicylic acid (Aspirin) administration, respectively, resulted in about 35-50% reduction of retinal neovascularization, compatible with a significant contribution of blood platelets in angiogenesis." | 3.72 | The functional role of blood platelet components in angiogenesis. ( Black, M; Fischer, S; Hammes, HP; Morgenstern, E; Preissner, KT; Rhee, JS; Schubert, U, 2004) |
| "The efficacy and safety of aspirin in the prevention and treatment of thrombosis in essential thrombocythaemia (ET) was retrospectively analysed in a cohort of 68 ET patients." | 3.69 | Prevention and treatment of thrombotic complications in essential thrombocythaemia: efficacy and safety of aspirin. ( Michiels, JJ; Mulder, PG; van de Moesdijk, D; van Genderen, PJ; Waleboer, M, 1997) |
| " In five cases, temporary reversal of the HELLP syndrome was achieved using low-dose aspirin and corticosteroids." | 3.68 | Prolongation of premature gestation in women with hemolysis, elevated liver enzymes and low platelets. A report of five cases. ( Burke, MS; Heyborne, KD; Porreco, RP, 1990) |
| "For 11 patients with confirmed heparin-induced thrombocytopenia, we used reversible platelet inhibition with iloprost, a stable prostacyclin analogue, to permit safe heparin administration for cardiac (n = 9) or vascular (n = 2) operations." | 3.68 | Intraoperative management of patients with heparin-induced thrombocytopenia. ( Addonizio, VP; Bell, P; Campbell, F; Ellison, N; Fisher, CA; Kappa, JR; Stenach, N; Todd, B, 1990) |
| "Previous studies have demonstrated that urinary thromboxane B2 (TXB2) excretion (UTXB2) and glomerular production of TXB2 are enhanced in experimental diabetes and that selective inhibitors of TX synthesis prevent or delay the development of albuminuria." | 3.68 | Contribution of platelet thromboxane production to enhanced urinary excretion and glomerular production of thromboxane and to the pathogenesis of albuminuria in the streptozotocin-diabetic rat. ( Craven, PA; DeRubertis, FR, 1992) |
| "We describe 2 patients with primary antiphospholipid syndrome in whom thrombocytopenia, which had not responded to high dose prednisone treatment, was promptly corrected after they started taking small doses (100 mg/day) of aspirin." | 3.67 | Correction of thrombocytopenia with small dose aspirin in the primary antiphospholipid syndrome. ( Alarcón-Segovia, D; Sánchez-Guerrero, J, 1989) |
| " The case was complicated due to a history of aspirin usage, marked obesity, and thrombocytopenia." | 3.67 | Femoral artery laceration complicating an intertrochanteric hip fracture: a multi-disciplinary therapeutic problem. ( Chmell, S; Haid, S; Milewski, S; Moss, GD; Pillars, JR, 1985) |
| "The first case of haemolytic anaemia with thrombocytopenia and acute renal failure induced by ingestion of aspirin in a 22-year old woman is reported." | 3.67 | [Immunoallergic hemolytic anemia, thrombopenia and acute renal failure induced by aspirin]. ( Debray, J; Habibi, B; Hubert, D; Krulik, M, 1984) |
| " Oral administration of ticlopidine inhibited the transient thrombocytopenia caused by ADP." | 3.66 | Inhibition of thrombocytopenic episodes caused by the Arthus reaction, the sub-lethal Forssman reaction and ADP. ( Butler, KD; White, AM, 1980) |
| "Pregnant women with either Type B EPH gestosis or gestosis alone were treated with low dose aspirin if thrombocytopenia were present (platelet counts below 75,000) or had platelet aggregation studies if their platelet counts were above 75,000." | 3.66 | Diagnosis and treatment of pregnancy induced platelet dysfunction. ( Davis, RB; Goodlin, RC, 1983) |
| " Pretreatment with carbenicillin, which markedly inhibited platelet aggregation or estradiol cypionate, which induced severe thrombocytopenia, significantly reduced the incidence of sudden death to 9% and zero, respectively." | 3.66 | Effect of inhibition of platelet function with carbenicillin or aspirin on experimental canine sudden death. ( Franciosa, J; Heckel, R; Johnson, GJ; Leis, LA, 1981) |
| "Three children with the hemolytic-uremic syndrome were treated with heparin, aspirin, and dipyridamole." | 3.65 | Preliminary report: treatment of the hemolytic-uremic syndrome with aspirin and dipyridamole. ( Arenson, EB; August, CS, 1975) |
| " It is sensitive to thrombocytopenia, aspirin administration, and von Willebrand's disease." | 3.65 | An in vitro measurement of bleeding time. ( Bailey, M; Bitmanis, J; Blakely, J; Girouard-Antonopoulos, E; Glynn, MF; Prchal, JT, 1977) |
| " A prolonged bleeding time is observed: (1) in thrombopathic thrombocytopenia, which may be (a) hereditary or (b) acquired, as in the immune types or from depression of bone marrow, and (2) athrombocytopenically, as in von Willebrand's disease, Glanzmann's thrombasthenia, or from aspirin intolerance." | 3.65 | The bleeding time as a test of hemostatic function. ( Quick, AJ, 1975) |
| "Reductions in thrombus area under high shear conditions correlated with reductions in platelet count (r²=0." | 2.79 | Antithrombotic properties of rafigrelide: a phase 1, open-label, non-randomised, single-sequence, crossover study. ( Balasubramaniam, K; Dragone, J; Grose-Hodge, R; Martin, P; Preston, P; Troy, S; Viswanathan, G; Zaman, AG, 2014) |
| " Monafram was introduced intravenously to 284 patients just before angioplasty at standard dosage - 0." | 2.75 | [Glycoprotein IIb-IIIa antagonist Monafram in primary angioplasty of patients with acute coronary syndrome without st segment elevation]. ( Frolova, NS; Mazurov, AV; Pevzner, DV; Ruda, MY; Samko, AN; Staroverov, II, 2010) |
| " In patients with stable CAD, platelet aggregation was dose dependently inhibited by RPR 109891, and the dose-response relation was shifted to the right by the concomitant administration of aspirin (p = 0." | 2.70 | Oral glycoprotein IIb/IIIa antagonism in patients with coronary artery disease. ( Catella-Lawson, F; Combe, S; Cucchiara, AJ; De Marco, S; FitzGerald, GA; Kapoor, S; Moretti, D; Ramsey, KE; Rocca, B; Theroux, P; Vigilante, GJ, 2001) |
| "Danaparoid sodium appears to be an efficient and safe treatment in critically ill patients with HIT." | 2.69 | Efficacy and safety of danaparoid sodium (ORG 10172) in critically ill patients with heparin-associated thrombocytopenia. ( Guyotat, D; Mahul, P; Mazet, E; Mismetti, P; Reynaud, J; Tardy, B; Tardy-Poncet, B, 1999) |
| "Major or severe bleeding (but not intracranial hemorrhage) was higher with orbofiban; it occurred in 2." | 2.69 | Oral glycoprotein IIb/IIIa inhibition with orbofiban in patients with unstable coronary syndromes (OPUS-TIMI 16) trial. ( Alexander, JC; Anders, RJ; Berink, P; Braunwald, E; Cannon, CP; Caspi, A; Charlesworth, A; Langer, A; Lopez-Sendon, J; McCabe, CH; Skene, A; Toman, J; Wilcox, RG, 2000) |
| " The optimal drug therapies and dosing strategies for reducing VTE risk are not well defined for many clinical situations, despite the availability of evidence-based guidelines from authoritative sources." | 2.46 | Issues in assessing and reducing the risk for venous thromboembolism. ( Dager, WE, 2010) |
| "Tirofiban is safe and effective in patients with ACS." | 2.46 | Safety evaluation of tirofiban. ( Tebaldi, M; Valgimigli, M, 2010) |
| "Recently, the thrombophilias have been revealed as risk factors for severe preeclampsia, abruptio placentae, fetal growth retardation, abortion and still birth as well." | 2.42 | [Anticoagulation and antiaggregation during pregnancy]. ( Biasiutti, FD; Strebel, JK, 2003) |
| "The risk of preeclampsia and placental insufficiency was substantial and occurred in 50% of patients." | 2.42 | Antiphospholipid syndrome in obstetrics. ( Heilmann, L; Pollow, K; von Tempelhoff, GF, 2003) |
| " The safety profiles of various GP IIb-IIIa inhibitors are largely a function of their pharmacokinetic and pharmacodynamic properties, most notably the reversibility of platelet inhibition and the rate of plasma clearance." | 2.40 | Pharmacokinetics and pharmacodynamics of glycoprotein IIb-IIIa inhibitors. ( Kleiman, NS, 1999) |
| "Under corticosteroid treatment, chorea disappeared and cardiac involvement stabilised." | 2.40 | Chorea as the presenting clinical feature of primary antiphospholipid syndrome in childhood. ( Ellemunter, H; Kiechl, S; Kiechl-Kohlendorfer, U, 1999) |
| "Cardiovascular (CV) disease prevention with low-dose aspirin can be less effective in patients with a faster recovery of platelet (PLT) cyclooxygenase (COX)-1 activity during the 24-hour dosing interval." | 1.91 | Reduced platelet glycoprotein Ibα shedding accelerates thrombopoiesis and COX-1 recovery: implications for aspirin dosing regimen. ( Abbonante, V; Auciello, R; Balduini, A; Bologna, G; Camera, M; Ciotti, S; Cipollone, F; Cufaro, MC; Del Boccio, P; Di Castelnuovo, A; Hoffmeister, KM; Lanuti, P; Lee-Sundlov, M; Liani, R; Luongo, M; Pieragostino, D; Porro, B; Recchiuti, A; Santilli, F; Simeone, P; Tremoli, E; Tripaldi, R, 2023) |
| "Aspirin treatment appears to be a reasonable choice for thrombocytopenic (> 30 × 109/l) patients with acute coronary syndrome." | 1.91 | [Which anticoagulant or antiplatelet treatment for cancer patients with thrombocytopenia ?] ( Azizi, MA; Efthymiou, A; Paoletti, M, 2023) |
| "His course was complicated by cytokine storm and COVID-19-associated coagulopathy." | 1.56 | Successful management of COVID-19 and associated coagulopathy in a patient with durable left ventricular assist device. ( Estep, J; Hodges, K; Hsich, E; Insler, J; Insler, S; Mubashir, M; Soltesz, E; Tong, M, 2020) |
| "Severe thrombocytopenia was identified in 36 patients (36." | 1.48 | Safety of Diagnostic and Therapeutic Cardiac Catheterization in Cancer Patients With Acute Coronary Syndrome and Chronic Thrombocytopenia. ( Balanescu, DV; Cilingiroglu, M; Donisan, T; Durand, JB; Giza, DE; Iliescu, C; Kim, PY; Lopez-Mattei, JC; Marmagkiolis, K; Mouhayar, EN; Mukerji, SS; Muñoz Gonzalez, ED; Palaskas, N; Song, J, 2018) |
| "Methods Antibody-mediated TRALI was experimentally induced in mice by lipopolysaccharide priming followed by the administration of an anti-MHC I mAb." | 1.43 | Platelets are dispensable for antibody-mediated transfusion-related acute lung injury in the mouse. ( de la Salle, H; El Mdawar, MB; Gachet, C; Hechler, B; Heim, V; Magnenat, S; Maître, B, 2016) |
| "Pocket hematoma is a troublesome complication associated with the implantation of cardiac implantable electronic devices (CIEDs)." | 1.39 | Thrombocytopenia, dual antiplatelet therapy, and heparin bridging strategy increase pocket hematoma complications in patients undergoing cardiac rhythm device implantation. ( Chang, JP; Chen, HC; Chen, MC; Chen, YL; Guo, BF; Lin, YS; Pan, KL; Tsai, TH, 2013) |
| "Remarkably, hyperalgesia evoked by Bjv or carrageenan was completely blocked in animals treated with ARPI or busulfan, or pre-treated with aspirin or clopidogrel." | 1.37 | Involvement of circulating platelets on the hyperalgesic response evoked by carrageenan and Bothrops jararaca snake venom. ( Cirillo, MC; Giorgi, R; Gonçalves, LR; Nogueira, TO; Sano-Martins, IS; Santoro, ML; Senise, LV; Yamashita, KM, 2011) |
| "Approaches to the treatment of acute coronary syndrome in patients with thrombocytopenia might be better directed toward the evaluation of platelet function rather than toward absolute platelet count, and the risk-benefit equation of invasive procedures and antithrombotic therapies may need to incorporate this information." | 1.36 | Antiplatelet therapy and percutaneous coronary intervention in patients with acute coronary syndrome and thrombocytopenia. ( Bathina, JD; Daher, IN; Durand, JB; Iliescu, C; Yusuf, SW, 2010) |
| "Profound thrombocytopenia has reportedly been an issue with abciximab, but not with tirofiban." | 1.32 | Repetitive profound thrombocytopenia after treatment with tirofiban: a case report. ( Erkoc, R; Eryonucu, B; Tuncer, M, 2004) |
| "Thrombocytopenia was produced by a polyclonal antiplatelet serum that depleted circulating platelet count by 84% without influencing neutrophil count." | 1.30 | Importance of platelets in neutrophil adhesion and vasoconstriction after deep carotid arterial injury by angioplasty in pigs. ( Guidoin, R; Latour, JG; Merhi, Y; Provost, P, 1997) |
| "Kasabach-Merritt syndrome is an infrequent combination of a giant hemangioma and severe thrombocytopenia." | 1.30 | -Neonatal Kasabach-Merritt syndrome healed by complete surgical excision of the angioma-. ( Dupont, D; Golkar, A; Valla, JS; Velin, P, 1998) |
| "Anemia and disseminated intravascular coagulation may develop." | 1.28 | [Kasabach-Merritt syndrome in children]. ( Andry, P; Bodemer, C; Brunelle, F; de Prost, Y; Hubert, P; Nihoul-Fékété, C; Sebag, G; Teillac-Hamel, D, 1992) |
| "A 35-year-old patient with symptomatic chronic renal failure secondary to hereditary nephritis underwent heparinization during urgent hemodialysis." | 1.28 | Heparin-induced thrombocytopenia in renal failure. ( Clark, WF; Hall, AV; Parbtani, A, 1992) |
| "Pre-treatment with aspirin (5 mg/kg), which inhibits the platelet-release reaction, also prevented the tachypnoeic response to both emboli and antiserum, although it did not prevent the fall in platelet count which following injection of antiserum." | 1.28 | The role of platelets in the reflex tachypnoeic response to miliary pulmonary embolism in anaesthetized rabbits. ( Armstrong, DJ; Miller, SA, 1990) |
| " This action carried over to ex vivo situation following intraduodenal dosing as demonstrated in rabbits." | 1.27 | Inhibition of platelet aggregation by a new agent, 2,2'-dithiobis-(N-2-hydroxypropyl benzamide) (KF4939). ( Nakamizo, N; Shuto, K; Yamada, K, 1983) |
| "Thrombocytopenia was induced in rabbits by the intraperitoneal injection of busulphan dissolved in polyethylene glycol (PEG) at a dose of 60 mg/kg." | 1.27 | A platelet release defect induced by aspirin or penicillin G does not increase gastrointestinal blood loss in thrombocytopenic rabbits. ( Giles, AR; Greenwood, P; Tinlin, S, 1984) |
| "Heparin-associated thrombocytopenia is mediated through IgG or IgM immunoglobulin fractions and is believed to be an immune phenomenon, with heparin acting as a hapten." | 1.27 | Plasmapheresis in the management of heparin-associated thrombocytopenia with thrombosis. ( Nand, S; Robinson, JA, 1988) |
| "In 8 patients with liver cirrhosis who underwent hepatectomy, one patient with a prolonged T2 (260 secs) and a normal skin BT bled postoperatively, however, 3 patients with a prolonged skin BT (greater than 15 min) and a normal T2 had no hemorrhagic complications." | 1.27 | Clinical application of a new in vitro bleeding time device on surgical patients. ( Itoh, T; Kambayashi, J; Mori, T; Sakon, M; Tsujinaka, T; Uemura, Y, 1988) |
| "Thrombocytopenia was observed in 10 (2." | 1.27 | Thrombocytopenia: a complication of Kawasaki disease. ( Akeda, H; Aoki, T; Fukushige, J; Hara, T; Hijii, T; Honda, S; Mizuno, Y; Sunagawa, H; Ueda, K; Yamaguchi, Y, 1988) |
| "025-16 micrograms/paw) were followed by a bell-shaped dose-response curve for oedema." | 1.27 | Interactions between local inflammatory and systemic haematological effects of PAF-acether in the rat. ( Castro, HC; Cordeiro, RS; Lima, MC; Martins, MA; Neto, F; Silva, PM; Vargaftig, BB, 1987) |
| "Pretreatment with aspirin (10 mg/kg) protected sheep against the pulmonary vascular response and completely blocked thromboxane synthesis." | 1.27 | Thromboxane synthesis by sources other than platelets in association with complement-induced pulmonary leukostasis and pulmonary hypertension in sheep. ( Ali, M; Cooper, JD; McDonald, JW; Morgan, E; Townsend, ER, 1983) |
| " An overestimation of rare side-effects of drugs should not block the application of certain medicaments, however, they should be given only in such a high dosage as it is necessary." | 1.26 | [Hematotoxic lesions caused by non-steroidal antirheumatic agents]. ( Hüge, W; Stobbe, H, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 105 (46.05) | 18.7374 |
| 1990's | 40 (17.54) | 18.2507 |
| 2000's | 41 (17.98) | 29.6817 |
| 2010's | 35 (15.35) | 24.3611 |
| 2020's | 7 (3.07) | 2.80 |
| Authors | Studies |
|---|---|
| Alamin, MA | 1 |
| Al-Mashdali, A | 1 |
| Al Kindi, DI | 1 |
| Elshaikh, EA | 1 |
| Othman, F | 1 |
| Simeone, P | 1 |
| Liani, R | 1 |
| Tripaldi, R | 1 |
| Ciotti, S | 1 |
| Recchiuti, A | 1 |
| Abbonante, V | 1 |
| Porro, B | 1 |
| Del Boccio, P | 1 |
| Di Castelnuovo, A | 1 |
| Lanuti, P | 1 |
| Camera, M | 1 |
| Pieragostino, D | 1 |
| Lee-Sundlov, M | 1 |
| Luongo, M | 1 |
| Auciello, R | 1 |
| Bologna, G | 1 |
| Cufaro, MC | 1 |
| Tremoli, E | 1 |
| Hoffmeister, KM | 1 |
| Cipollone, F | 1 |
| Balduini, A | 1 |
| Santilli, F | 1 |
| Paoletti, M | 1 |
| Azizi, MA | 1 |
| Efthymiou, A | 1 |
| Hodges, K | 1 |
| Mubashir, M | 1 |
| Insler, J | 1 |
| Estep, J | 1 |
| Hsich, E | 1 |
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| Greenberg, CS | 2 |
| Lowe, JE | 1 |
| Jergens, AE | 1 |
| Turrentine, MA | 1 |
| Kraus, KH | 1 |
| Johnson, GS | 1 |
| Mannucci, PM | 1 |
| Vicente, V | 1 |
| Vianello, L | 1 |
| Cattaneo, M | 1 |
| Alberca, I | 1 |
| Coccato, MP | 1 |
| Faioni, E | 1 |
| Mari, D | 1 |
| Blockmans, D | 1 |
| Bounameaux, H | 1 |
| Vermylen, J | 1 |
| Verstraete, M | 1 |
| Hatsuoka, M | 1 |
| Seiki, M | 1 |
| Sasaki, K | 1 |
| Kashii, A | 1 |
| Remacle-Volon, G | 1 |
| Martins, MA | 1 |
| Silva, PM | 1 |
| Castro, HC | 1 |
| Neto, F | 1 |
| Lima, MC | 1 |
| Cordeiro, RS | 1 |
| Brace, LD | 1 |
| Fareed, J | 1 |
| Tomeo, J | 1 |
| Issleib, S | 1 |
| Janzarik, H | 1 |
| Remy, S | 1 |
| Morell, S | 1 |
| Pabst, W | 1 |
| Castaldi, PA | 1 |
| Moss, GD | 1 |
| Chmell, S | 1 |
| Pillars, JR | 1 |
| Haid, S | 1 |
| Milewski, S | 1 |
| Carr, ME | 1 |
| Gabriel, DA | 1 |
| O'Brien, JR | 1 |
| Etherington, M | 1 |
| Jamieson, S | 1 |
| Lawford, P | 1 |
| Jobin, F | 1 |
| DeLage, JM | 1 |
| Santangelo, G | 1 |
| Barberi, I | 1 |
| Maccarrone, N | 1 |
| Palumbo, A | 1 |
| McPherson, VJ | 1 |
| Zucker, MB | 1 |
| Friedberg, NM | 1 |
| Rifkin, PL | 1 |
| Pochedly, C | 1 |
| Ente, G | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Multicenter, Double-Blind, Study to Evaluate the Efficacy of Tirofiban HCl Versus Placebo in the Setting of Standard Therapies Among Subjects Undergoing Percutaneous Coronary Intervention[NCT01245725] | Phase 3 | 0 participants (Actual) | Interventional | Withdrawn (stopped due to Study was not initiated, change in clinical development) | |||
| Low-molecular-weight Heparin Versus Unfractionated Heparin in Pregnant Women With History of Recurrent Abortion Secondary to Antiphospholipid Syndrome. A Randomized Controlled Trial[NCT01051778] | Phase 2 | 60 participants (Actual) | Interventional | 2006-06-30 | Completed | ||
| A Single-center, Randomized, Open-label, Controlled, Dose-escalating, Parallel-group Study to Assess the Anti-platelet Effect of Berberine in Patients Receiving Aspirin and Clopidogrel After Percutaneous Coronary Intervention[NCT03378934] | Phase 4 | 64 participants (Anticipated) | Interventional | 2018-09-26 | Recruiting | ||
| Prevention of Pre-eclampsia Using Metformin: a Randomized Control Trial[NCT04855513] | 414 participants (Anticipated) | Interventional | 2022-03-24 | Not yet recruiting | |||
| Randomized, Controlled, Prospective Trial to Evaluate the Hemostatic Effect of Lyostypt® Versus Surgicel® in Arterial Bypass Anastomosis[NCT00837954] | Phase 4 | 32 participants (Actual) | Interventional | 2009-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Live birth occurs when a fetus (> 24 weeks ) , exits the maternal body and subsequently shows signs of life, such as voluntary movement, heartbeat, or pulsation of the umbilical cord. (NCT01051778)
Timeframe: pregnancy > 24weeks gestation
| Intervention | Percentage of pregnancies (Number) |
|---|---|
| Enoxaparin 40 mg /Day Plus Low Dose Aspirin | 24 |
| Heparin Calcium 5,000 U Twice Daily Plus Low Dose Aspirin | 20 |
36 reviews available for aspirin and Thrombopenia
| Article | Year |
|---|---|
Therapeutic drug-induced platelet apoptosis: an overlooked issue in pharmacotoxicology.
Topics: Apoptosis; Aspirin; Blood Platelets; Cisplatin; Drug-Related Side Effects and Adverse Reactions; Hum | 2014 |
Thrombocytopenia in acute coronary syndromes: etiologies and proposed management.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Therapy, Combina | 2015 |
[Acquired platelet function disorders: pathogenesis, classification, frequency, diagnosis, clinical management].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelet Disorders; Blood Platelets; Coronar | 2008 |
Antiphospholipid antibody syndrome.
Topics: Abortion, Habitual; Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Aspirin; Blood Transfus | 2009 |
[Medicinal therapy for interventional surgery of the peripheral vascular system].
Topics: Administration, Oral; Anticoagulants; Arterial Occlusive Diseases; Aspirin; Clopidogrel; Drug Therap | 2010 |
Issues in assessing and reducing the risk for venous thromboembolism.
Topics: Anticoagulants; Aspirin; Fondaparinux; Heparin, Low-Molecular-Weight; Humans; Polysaccharides; Risk | 2010 |
Safety evaluation of tirofiban.
Topics: Abciximab; Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; | 2010 |
Prevention of thrombosis during pregnancy.
Topics: Administration, Oral; Anticoagulants; Antiphospholipid Syndrome; Aspirin; Blood Coagulation Tests; B | 2002 |
[Anticoagulation and antiaggregation during pregnancy].
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Abruptio Placentae; Administration, Oral; Adult; | 2003 |
Antiphospholipid syndrome in obstetrics.
Topics: Abortion, Habitual; Abortion, Spontaneous; Adult; Annexin A5; Antibodies, Anticardiolipin; Anticoagu | 2003 |
Late bleeding from right internal mammary artery after HeartMate left ventricular assist device implantation.
Topics: Adult; Anticoagulants; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Cardiomyopathy, Dila | 2004 |
Practical aspects of treatment with drotrecogin alfa (activated).
Topics: Adult; Aged; Anti-Infective Agents; APACHE; Aspirin; Child; Clinical Trials as Topic; Cost-Benefit A | 2007 |
Bleeding associated with antithrombotic therapy.
Topics: 4-Hydroxycoumarins; Aspirin; Dextrans; Dipyridamole; Dose-Response Relationship, Drug; Fibrinolytic | 1980 |
Increased platelet destruction.
Topics: Aspirin; beta-Thromboglobulin; Blood Platelets; Bone Marrow; Cell Membrane; Cell Survival; Chromium | 1982 |
[Untoward side effects of acetylsalicylic acid].
Topics: Adolescent; Adult; Angioedema; Aspirin; Asthma; Child; Child, Preschool; Female; Fetus; Gastrointest | 1984 |
Potential role of platelets in the pathogenesis of tumor metastasis.
Topics: Animals; Aspirin; Blood Platelets; Capillary Permeability; Cell Transformation, Neoplastic; Endothel | 1984 |
Identification & management of defects in platelet hemostasis in massively transfused patients.
Topics: Animals; Aspirin; Bleeding Time; Blood Preservation; Blood Transfusion; Cardiopulmonary Bypass; Cell | 1982 |
Acquired disorders of platelet function.
Topics: Alcoholism; Amyloidosis; Anti-Bacterial Agents; Aspirin; Blood Platelet Disorders; Blood Platelets; | 1980 |
[Therapeutic management of antiphospholipid antibody syndrome in pregnancy].
Topics: Adrenal Cortex Hormones; Antiphospholipid Syndrome; Aspirin; Female; Heparin; Humans; Pregnancy; Pre | 1993 |
[The measurement of platelet life span].
Topics: Arachidonic Acids; Aspirin; Blood Platelets; Erythrocyte Aging; Humans; Indium Radioisotopes; Malond | 1997 |
ACOG educational bulletin. Antiphospholipid syndrome. Number 244, February 1998. American College of Obstetricians and Gynecologists.
Topics: Antibodies, Antiphospholipid; Anticoagulants; Antiphospholipid Syndrome; Aspirin; Female; Heparin; H | 1998 |
[Management of a suspicion of heparin-induced thrombopenia].
Topics: Anticoagulants; Aspirin; Heparin; Hirudin Therapy; Humans; Platelet Aggregation Inhibitors; Risk Fac | 1998 |
[Heparin-induced thrombocytopenia].
Topics: Anticoagulants; Antithrombins; Arginine; Aspirin; Diagnosis, Differential; Fibrinolytic Agents; Hepa | 1998 |
Diagnosis, pathogenesis and treatment of the myeloproliferative disorders essential thrombocythemia, polycythemia vera and essential megakaryocytic granulocytic metaplasia and myelofibrosis.
Topics: Aspirin; Bone Marrow; Bone Marrow Transplantation; Diagnosis, Differential; Follow-Up Studies; Granu | 1999 |
Chorea as the presenting clinical feature of primary antiphospholipid syndrome in childhood.
Topics: Adolescent; Adrenal Cortex Hormones; Antibodies, Anticardiolipin; Antibodies, Antinuclear; Antiphosp | 1999 |
Pharmacokinetics and pharmacodynamics of glycoprotein IIb-IIIa inhibitors.
Topics: Anticoagulants; Aspirin; Drug Combinations; Fibrinolytic Agents; Hemorrhage; Hemostasis; Heparin; Hu | 1999 |
[Therapeutic use of intravenous immunoglobulins in the antiphospholipid syndrome].
Topics: Abortion, Habitual; Abortion, Spontaneous; Anticoagulants; Antiphospholipid Syndrome; Aspirin; Femal | 2000 |
Low-molecular-weight heparin and other antithrombotic agents in the setting of a fast-track revascularization in unstable coronary artery disease.
Topics: Abciximab; Angina, Unstable; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; | 2000 |
Abnormal coagulation in the postoperative period contributing to excessive bleeding.
Topics: Adult; Anticoagulants; Aspirin; Blood Coagulation; Blood Coagulation Disorders; Blood Transfusion; D | 2001 |
Current trends in essential thrombocythaemia.
Topics: Acute Disease; Aspirin; Bone Marrow Examination; Clone Cells; Dosage Compensation, Genetic; Heparin, | 2002 |
Heparin-induced thrombocytopenia and arterial thrombosis: alternative therapies.
Topics: Aspirin; Cardiopulmonary Bypass; Chondroitin Sulfates; Dermatan Sulfate; Epoprostenol; Fibrinolytic | 1990 |
[New pathogenetic aspects of platelet pathology in childhood].
Topics: Aspirin; Autoantibodies; Blood Coagulation; Blood Platelet Disorders; Blood Platelets; Female; Human | 1972 |
Adverse hematologic effects of drugs.
Topics: Anemia, Hemolytic; Anemia, Macrocytic; Anti-Bacterial Agents; Anticonvulsants; Antidepressive Agents | 1972 |
The clinical relevance of platelet function tests.
Topics: Adenosine Diphosphate; Aspirin; Blood Cell Count; Blood Coagulation Factors; Blood Coagulation Tests | 1972 |
Allergy in adverse drug reactions.
Topics: Abnormalities, Drug-Induced; Adult; Age Factors; Aged; Anemia, Aplastic; Anemia, Hemolytic; Anemia, | 1973 |
Platelet function.
Topics: Adenine Nucleotides; Afibrinogenemia; Age Factors; Anemia, Hypochromic; Animals; Aspirin; Blood Cell | 1969 |
14 trials available for aspirin and Thrombopenia
| Article | Year |
|---|---|
Antithrombotic properties of rafigrelide: a phase 1, open-label, non-randomised, single-sequence, crossover study.
Topics: Adult; Aspirin; Blood Coagulation; Blood Platelets; Cross-Over Studies; Drug Therapy, Combination; H | 2014 |
[Glycoprotein IIb-IIIa antagonist Monafram in primary angioplasty of patients with acute coronary syndrome without st segment elevation].
Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Clop | 2010 |
Enoxaparin versus unfractionated heparin in the management of recurrent abortion secondary to antiphospholipid syndrome.
Topics: Abortion, Habitual; Adult; Antibodies, Antiphospholipid; Anticoagulants; Antiphospholipid Syndrome; | 2011 |
Safety of clopidogrel in older patients: a nonrandomized, parallel-group, controlled, two-centre study.
Topics: Acute Coronary Syndrome; Administration, Cutaneous; Age Factors; Aged; Angioplasty, Balloon, Coronar | 2011 |
Drug-induced thrombocytopenia and thrombosis: evidence from patients receiving an oral glycoprotein IIb/IIIa inhibitor in the Orbofiban in Patients with Unstable coronary Syndromes- (OPUS-TIMI 16) trial.
Topics: Aged; Alanine; Angina, Unstable; Aspirin; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; | 2006 |
Use of unfractionated heparin and a low-molecular-weight heparin following thrombolytic therapy for acute ST-segment elevation myocardial infarction.
Topics: Aged; Aspirin; Blood Coagulation; Drug Administration Schedule; Drug Therapy, Combination; Electroca | 2006 |
Efficacy and safety of danaparoid sodium (ORG 10172) in critically ill patients with heparin-associated thrombocytopenia.
Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Blood Coagulation Factors; Chondroitin Sulf | 1999 |
Comparative safety and tolerability of clopidogrel and aspirin: results from CAPRIE. CAPRIE Steering Committee and Investigators. Clopidogrel versus aspirin in patients at risk of ischaemic events.
Topics: Arteriosclerosis; Aspirin; Cerebrovascular Disorders; Clopidogrel; Double-Blind Method; Gastrointest | 1999 |
Risks of preeclampsia and adverse neonatal outcomes among women with pregestational diabetes mellitus. National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units.
Topics: Aspirin; Birth Weight; Blood Pressure; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; | 2000 |
Oral glycoprotein IIb/IIIa inhibition with orbofiban in patients with unstable coronary syndromes (OPUS-TIMI 16) trial.
Topics: Administration, Oral; Alanine; Anticoagulants; Aspirin; Coronary Disease; Double-Blind Method; Femal | 2000 |
Oral glycoprotein IIb/IIIa antagonism in patients with coronary artery disease.
Topics: Administration, Oral; Adult; Aged; Aspirin; Coronary Disease; Dose-Response Relationship, Drug; Doub | 2001 |
Abciximab readministration: results of the ReoPro Readministration Registry.
Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies; Antibodies, Monoclonal; Aspirin; Coronary Dis | 2001 |
The absence of influence of acetylsalicylic acid (ASA) on the transient decrease in platelet counts observed after infusion of bleomycin and vinblastine.
Topics: Adult; Aspirin; Bleomycin; Drug Synergism; Humans; Male; Middle Aged; Platelet Count; Prospective St | 1985 |
Controlled trial of desmopressin in liver cirrhosis and other conditions associated with a prolonged bleeding time.
Topics: Adolescent; Adult; Aged; Aspirin; Bleeding Time; Clinical Trials as Topic; Deamino Arginine Vasopres | 1986 |
178 other studies available for aspirin and Thrombopenia
| Article | Year |
|---|---|
Eptifibatide-induced acute profound thrombocytopenia: A case report.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Eptifibatide; Glycoproteins; Hemorrhage; Humans; Male | 2022 |
Reduced platelet glycoprotein Ibα shedding accelerates thrombopoiesis and COX-1 recovery: implications for aspirin dosing regimen.
Topics: Aspirin; Blood Platelets; Diabetes Mellitus, Type 2; Humans; Platelet Membrane Glycoproteins; Thromb | 2023 |
[Which anticoagulant or antiplatelet treatment for cancer patients with thrombocytopenia ?]
Topics: Anemia; Anticoagulants; Aspirin; Humans; Neoplasms; Platelet Aggregation Inhibitors; Thrombocytopeni | 2023 |
Successful management of COVID-19 and associated coagulopathy in a patient with durable left ventricular assist device.
Topics: Adult; Anticoagulants; Aspirin; Biomarkers; Blood Transfusion; COVID-19; Cytokine Release Syndrome; | 2020 |
Atypical Spontaneous Hematomas in a Patient with Severe Coronavirus Disease 2019 (COVID-19).
Topics: Aged, 80 and over; Aspirin; Betacoronavirus; Coronavirus Infections; COVID-19; Erythrocyte Transfusi | 2020 |
Impact of Thrombocytopenia on Postoperative Bleeding Incidence in Patients Receiving Aspirin Following Coronary Artery Bypass Grafting.
Topics: Aspirin; Coronary Artery Bypass; Humans; Incidence; Platelet Aggregation Inhibitors; Postoperative H | 2022 |
Antioxidant prevents clearance of hemostatically competent platelets after long-term cold storage.
Topics: Acetylcysteine; Animals; Antioxidants; Aspirin; Bleeding Time; Blood Platelets; Blood Preservation; | 2021 |
Factors associated with adverse pregnancy outcomes in women with antiphospholipid syndrome: A multicenter study.
Topics: Adult; Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Aspirin; Female; Heparin; Humans; Hy | 2017 |
Safety of Diagnostic and Therapeutic Cardiac Catheterization in Cancer Patients With Acute Coronary Syndrome and Chronic Thrombocytopenia.
Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Aspirin; Cardiac Catheterization; Chronic D | 2018 |
Thrombocytopenia, dual antiplatelet therapy, and heparin bridging strategy increase pocket hematoma complications in patients undergoing cardiac rhythm device implantation.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; China; Clopidogrel; Cross-Sectional Studies; Defib | 2013 |
Chronic subdural hematoma in elderly patient with EDTA-dependent pseudothrombocytopenia recently treated with aspirin and warfarin: case report.
Topics: Aged; Anticoagulants; Aspirin; Calcium; Chelating Agents; Diagnosis, Differential; Diagnostic Errors | 2014 |
[Bullous hemorrhagic dermatosis induced by heparin: description of 2 new cases].
Topics: Aged; Anticoagulants; Aspirin; Brain Ischemia; Cerebral Hemorrhage; Drug Eruptions; Enoxaparin; Hemo | 2014 |
Incidence of Non-Traumatic Subconjunctival Hemorrhage in a Nationwide Study in Taiwan from 2000 to 2011.
Topics: Adolescent; Adult; Aged; Aspirin; Child; Comorbidity; Conjunctiva; Conjunctival Diseases; Eye Hemorr | 2015 |
Prevention of deep vein thrombosis. First choice treatments.
Topics: Anticoagulants; Aspirin; Drug Therapy, Combination; Early Ambulation; Heparin, Low-Molecular-Weight; | 2015 |
Impact of Anemia and Dual Antiplatelet Therapy on Mortality in Patients Undergoing Percutaneous Coronary Intervention with Drug-Eluting Stents.
Topics: Aged; Anemia; Aspirin; Coronary Artery Disease; Drug-Eluting Stents; Female; Follow-Up Studies; Glom | 2015 |
Simultaneous transcatheter closure of an atrial septal defect and patent ductus arteriosus in an adult case, followed by thrombocytopenia and subclinical hemolysis.
Topics: Aged; Aspirin; Cardiac Catheterization; Ductus Arteriosus, Patent; Female; Heart Septal Defects, Atr | 2016 |
Platelets are dispensable for antibody-mediated transfusion-related acute lung injury in the mouse.
Topics: Animals; Antibodies, Monoclonal; Aspirin; Blood Platelets; Blood Transfusion; Clopidogrel; Diphtheri | 2016 |
Repeated failed non-invasive prenatal testing in a woman with immune thrombocytopenia and antiphospholipid syndrome: lessons learnt.
Topics: Abortion, Induced; Adult; Antiphospholipid Syndrome; Aspirin; Female; Fetal Growth Retardation; Gene | 2016 |
Aspirin Is Associated with Improved Survival in Severely Thrombocytopenic Cancer Patients with Acute Myocardial Infarction.
Topics: Acute Disease; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Humans; Male; Myocard | 2017 |
Thrombocytopenia in patients treated with heparin, combination antiplatelet therapy, and intra-aortic balloon pump counterpulsation.
Topics: Anticoagulants; Aspirin; Cohort Studies; Drug Therapy, Combination; Female; Heparin; Humans; Inciden | 2008 |
The prevalence of intolerance for low-dose acetylsalicylacid in the secondary prevention of atherothrombosis.
Topics: Administration, Oral; Aged; Angioedema; Aspirin; Dose-Response Relationship, Drug; Embolism, Cholest | 2009 |
Incidence and prognostic significance of thrombocytopenia developed during acute coronary syndrome in contemporary clinical practice.
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Angina, Unstable; Anticoagulants; Aspirin; Clopido | 2009 |
[Clinical and laboratory aspects of the Aspirin-like defect as hereditary thrombocytopathy].
Topics: Aspirin; Blood Coagulation Disorders; Blood Platelet Disorders; Family; Female; Hemorrhagic Disorder | 2009 |
Stroke recurrence in an elderly CADASIL patient on aspirin discontinuation due to severe auto-immune thrombocytopenia.
Topics: Aged, 80 and over; Aspirin; Autoimmune Diseases; CADASIL; Exons; Humans; Male; Receptor, Notch3; Rec | 2010 |
Antiplatelet therapy and percutaneous coronary intervention in patients with acute coronary syndrome and thrombocytopenia.
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Clopidogr | 2010 |
Acute myocardial infarction in a patient with chronic myelocytic leukemia during chemotherapy with hydroxyurea.
Topics: Angioplasty, Balloon, Coronary; Anterior Wall Myocardial Infarction; Antineoplastic Agents; Aspirin; | 2010 |
Systemic lupus erythematosus in a 3-month old male presenting as thrombocytopenia.
Topics: Aspirin; Fibrinolytic Agents; Glucocorticoids; Humans; Immunosuppressive Agents; Infant; Lupus Eryth | 2011 |
Left main stent thrombosis complicated by eptifibatide-induced acute thrombocytopenia.
Topics: Acute Disease; Angioplasty, Balloon, Coronary; Aspirin; Cardiac Catheterization; Clopidogrel; Corona | 2011 |
Involvement of circulating platelets on the hyperalgesic response evoked by carrageenan and Bothrops jararaca snake venom.
Topics: Animals; Aspirin; Blood Platelets; Bothrops; Busulfan; Carrageenan; Clopidogrel; Crotalid Venoms; Cy | 2011 |
Pentadecapeptide BPC 157 reduces bleeding time and thrombocytopenia after amputation in rats treated with heparin, warfarin or aspirin.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Bleeding Time; Heparin; Male; Peptide Fragments; Proteins; Rats | 2012 |
Multicolor flow cytometry for evaluation of platelet surface antigens and activation markers.
Topics: Aspirin; Blood Platelets; Clopidogrel; Flow Cytometry; Humans; Platelet Activation; Platelet Aggrega | 2012 |
Do aspirin and non-steroidal anti-inflammatory drugs increase the risk of post-sphincterotomy hemorrhage--a case-control study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-C | 2013 |
Massive epistaxis in a patient with Eisenmenger syndrome: illustrating the clot-versus-bleed conundrum.
Topics: Adult; Aspirin; Clopidogrel; Eisenmenger Complex; Epistaxis; Female; Humans; Platelet Aggregation In | 2011 |
Sub-optimal inhibition of thrombus formation ex vivo by aspirin in patients with primary thrombocythaemia.
Topics: Aspirin; Blood Coagulation; Female; Humans; Male; Platelet Aggregation Inhibitors; Thrombocytopenia; | 2012 |
[Antiaggregation therapy after percutaneous coronary intervention in a patient with thrombocytopenia: case report].
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Humans; Male; Platelet Aggregation; Plat | 2011 |
[Bleeding tendency].
Topics: Antithrombins; Aspirin; Blood Coagulation Disorders; Blood Platelet Disorders; Hemorrhagic Disorders | 2012 |
Thrombocytopenia induced by both aspirin and clopidogrel in the same patient.
Topics: Aged; Aspirin; Clopidogrel; Female; Humans; Platelet Aggregation Inhibitors; Thrombocytopenia; Ticlo | 2013 |
Protein A immunoadsorption in a pregnant woman with habitual abortion.
Topics: Abortion, Habitual; Abortion, Spontaneous; Activated Protein C Resistance; Adult; Anticoagulants; An | 2002 |
Combined treatment with nafamostat mesilate and aspirin prevents heparin-induced thrombocytopenia in a hemodialysis patient.
Topics: Adult; Anticoagulants; Aspirin; Benzamidines; Extracorporeal Circulation; Guanidines; Heparin; Human | 2003 |
Regression of intracardiac heparin-induced thrombosis after aortic root surgery.
Topics: Aged; Anticoagulants; Aortic Aneurysm, Thoracic; Aspirin; Blood Vessel Prosthesis; Clopidogrel; Drug | 2003 |
Evans syndrome associated with antiphospholipid antibodies.
Topics: Adolescent; Anemia, Hemolytic, Autoimmune; Antibodies, Antinuclear; Antibodies, Antiphospholipid; An | 2003 |
[SHOCK-LIKE SYMPTOMS CAUSED BY DRUGS AND THEIR TREATMENT. (2) CLINICAL ASPECTS].
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Aspirin; Blood Chemical Analysis; Body Constitut | 1963 |
THROMBOCYTOPENIA ASSOCIATED WITH THE USE OF ACETYLSALICYLIC ACID.
Topics: Aspirin; Thrombocytopenia; Toxicology | 1964 |
The functional role of blood platelet components in angiogenesis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Component Transfusion; Blood Platel | 2004 |
Immune heparin-induced thrombocytopenia can occur in patients receiving clopidogrel and aspirin.
Topics: Adenosine Diphosphate; Adult; Aged; Antibodies, Monoclonal; Anticoagulants; Aspirin; Clopidogrel; Fe | 2005 |
Repetitive profound thrombocytopenia after treatment with tirofiban: a case report.
Topics: Angioplasty, Balloon; Arterial Occlusive Diseases; Aspirin; Clopidogrel; Drug Administration Schedul | 2004 |
Adverse reactions to anticoagulants and to antiplatelet drugs recorded by the German spontaneous reporting system.
Topics: Administration, Oral; Adverse Drug Reaction Reporting Systems; Anticoagulants; Aspirin; Association; | 2005 |
Successful preconceptional prophylactic treatment with combined acetyl salicylic acid and low-molecular heparin (Fragmin) in a case of antiphospholipid-antibody syndrome with prior life-threatening hemolysis, elevated liver enzymes and low-platelet syndro
Topics: Anticoagulants; Antiphospholipid Syndrome; Aspirin; Drug Therapy, Combination; Female; HELLP Syndrom | 2005 |
Pro: Should aspirin be continued after cardiac surgery in the setting of thrombocytopenia?
Topics: Anticoagulants; Aspirin; Coronary Artery Bypass; Humans; Platelet Count; Thrombocytopenia | 2006 |
Con: Should aspirin be continued after cardiac surgery in the setting of thrombocytopenia?
Topics: Anticoagulants; Aspirin; Cardiopulmonary Bypass; Coronary Artery Bypass; Humans; Platelet Count; Thr | 2006 |
[Constrictive pericarditis after inferoposterior myocardial infarction].
Topics: Abciximab; Angioplasty, Balloon; Antibodies, Monoclonal; Anticoagulants; Aspirin; Heart Failure; Hep | 2006 |
Impact of aspirin therapy in cancer patients with thrombocytopenia and acute coronary syndromes.
Topics: Acute Disease; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Coronary Disease; Female; Hem | 2007 |
Hemorrhagic foreign body granuloma after cutaneous surgery occurring in the setting of aspirin therapy or thrombocytopenia: a presentation of six cases.
Topics: Aged; Aged, 80 and over; Aspirin; Biopsy; Diagnosis, Differential; Female; Fibrinolytic Agents; Gran | 2008 |
The Duke bleeding time.
Topics: Aspirin; Blood Coagulation Disorders; Blood Coagulation Tests; Cold Temperature; Hemophilia A; Hemor | 1967 |
[Immunoallergic hemolytic anemia, thrombopenia and acute renal failure induced by aspirin].
Topics: Acute Kidney Injury; Adult; Anemia, Hemolytic; Aspirin; Female; Humans; Immunoglobulin M; Thrombocyt | 1984 |
Studies of human plate alpha-granule release in vivo.
Topics: Adenosine; Adult; Anticoagulants; Aspirin; beta-Thromboglobulin; Blood Platelets; Blood Specimen Col | 1981 |
Platelet malondialdehyde production kinetics after cyclooxygenase block. A study performed with a modified high sensitivity assay.
Topics: Adult; Aged; Aspirin; Blood Platelets; Cell Survival; Cyclooxygenase Inhibitors; Humans; Lung Diseas | 1983 |
Inhibition of platelet aggregation by a new agent, 2,2'-dithiobis-(N-2-hydroxypropyl benzamide) (KF4939).
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Benzamides; Collagen; | 1983 |
Activation of blood coagulation in cancer: Trousseau's syndrome revisited.
Topics: Antibodies; Aspirin; Blood Coagulation Disorders; Blood Coagulation Factors; Blood Platelets; Cell A | 1983 |
Inhibition of thrombocytopenic episodes caused by the Arthus reaction, the sub-lethal Forssman reaction and ADP.
Topics: Adenosine Diphosphate; Animals; Antibodies; Arthus Reaction; Aspirin; Dipyridamole; Forssman Antigen | 1980 |
A platelet release defect induced by aspirin or penicillin G does not increase gastrointestinal blood loss in thrombocytopenic rabbits.
Topics: Animals; Aspirin; Blood Platelet Disorders; Busulfan; Gastrointestinal Hemorrhage; Male; Penicillin | 1984 |
Thromboxane synthesis by sources other than platelets in association with complement-induced pulmonary leukostasis and pulmonary hypertension in sheep.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Platelets; Complement Activation; Female; Hype | 1983 |
Fatal hemorrhage from minor trauma following massive salicylate ingestion.
Topics: Alcoholism; Aspirin; Death, Sudden; Hemorrhage; Humans; Lung Diseases; Male; Mediastinal Diseases; M | 1984 |
Appearance of thrombocytopenia and benign monoclonal gammopathy following intake of drugs.
Topics: Aged; Ampicillin; Aspirin; Dipyrone; Female; Humans; Hypergammaglobulinemia; Indomethacin; Male; Mid | 1982 |
Aspirin prevents heparin-induced platelet aggregation in vivo.
Topics: Aspirin; Heparin; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Count; Renal Dialysis; T | 1983 |
Correction of pregnancy-related thrombocytopenia with aspirin without improvement in fetal outcome.
Topics: Aspirin; Dose-Response Relationship, Drug; Female; Fetal Death; Fetal Growth Retardation; Humans; Pl | 1983 |
Diagnosis and treatment of pregnancy induced platelet dysfunction.
Topics: Adult; Aspirin; Dexamethasone; Female; Humans; Plasma Substitutes; Platelet Aggregation; Pre-Eclamps | 1983 |
"Aspirinated" platelets are hemostatic in thrombocytopenic rats with "nonaspirinated" vessel walls--evidence from an exchange transfusion model.
Topics: Animals; Arachidonic Acids; Aspirin; Bleeding Time; Blood Vessels; Disease Models, Animal; Epoproste | 1980 |
Effect of inhibition of platelet function with carbenicillin or aspirin on experimental canine sudden death.
Topics: Animals; Arterial Occlusive Diseases; Aspirin; Blood Platelets; Carbenicillin; Coronary Disease; Dea | 1981 |
Heparin-induced thrombocytopenia: effect of heparin platelet antibody on platelets.
Topics: Adenosine Diphosphate; Adult; Antibodies; Aspirin; Blood Platelets; Complement Fixation Tests; Dipyr | 1981 |
Impaired thromboxane production by newly formed platelets after aspirin administration to thrombocytopenic rats.
Topics: Animals; Aspirin; Blood Platelets; Male; Malondialdehyde; Platelet Count; Rats; Thrombocytopenia; Th | 1980 |
[Hematotoxic lesions caused by non-steroidal antirheumatic agents].
Topics: Adult; Aged; Agranulocytosis; Anemia, Aplastic; Arthritis, Rheumatoid; Aspirin; Diclofenac; Female; | 1980 |
Management of cardiopulmonary bypass in a patient with heparin-induced thrombocytopenia using prostaglandin E1 and aspirin.
Topics: Aged; Alprostadil; Angina, Unstable; Aspirin; Cardiopulmonary Bypass; Coronary Artery Bypass; Female | 1994 |
Resolution of thrombocytopenia in a patient with lupus anticoagulant who received warfarin therapy.
Topics: Adult; Antiphospholipid Syndrome; Aspirin; Drug Therapy, Combination; Humans; Lupus Coagulation Inhi | 1994 |
Renal coagulopathy, thrombocytopenia, and the anticardiolipin antibody: therapeutic response to corticosteroids and aspirin but not anticoagulation.
Topics: Adolescent; Antibodies, Anticardiolipin; Aspirin; Blood Coagulation Disorders; Humans; Male; Prednis | 1994 |
[Thrombocytopenia due to therapeutic drugs].
Topics: Aspirin; Blood Platelets; Cephalosporins; Heparin; Humans; Immunoglobulin G; Platelet Count; Quinidi | 1993 |
Pregnancy outcome in women with antiphospholipid antibodies.
Topics: Abortion, Habitual; Adult; Antibodies, Antiphospholipid; Aspirin; Female; Humans; Immune System Dise | 1993 |
Low molecular weight heparin-induced thrombocytopenia and thrombosis.
Topics: Adenocarcinoma; Aged; Arterial Occlusive Diseases; Aspirin; Dextrans; Embolism; Female; Femoral Arte | 1996 |
[Is thrombocytopenia in primary antiphospholipid syndrome a contraindication for aspirin?].
Topics: Adult; Antiphospholipid Syndrome; Aspirin; Contraindications; Female; Humans; Thrombocytopenia | 1996 |
Changes in blood counts after the administration of granulocyte-colony-stimulating factor and the collection of peripheral blood stem cells from healthy donors.
Topics: Adult; Aspirin; Contraindications; Filgrastim; Follow-Up Studies; Granulocyte Colony-Stimulating Fac | 1996 |
Platelets of patients with peripheral arterial disease are hypersensitive to heparin.
Topics: Adult; Anticoagulants; Arteries; Aspirin; Blood Platelets; Case-Control Studies; Combined Modality T | 1996 |
Prevention and treatment of thrombotic complications in essential thrombocythaemia: efficacy and safety of aspirin.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cohort Studies; Female; Follow-Up Studies; Hemorrhage; Huma | 1997 |
Importance of platelets in neutrophil adhesion and vasoconstriction after deep carotid arterial injury by angioplasty in pigs.
Topics: Angioplasty, Balloon; Animals; Aspirin; Blood Platelets; Carotid Artery Injuries; Cell Adhesion; Mic | 1997 |
Antiplatelet therapy or low-dose heparin and neuraxial anaesthesia.
Topics: Anesthesia, Epidural; Anesthesia, Spinal; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; A | 1997 |
Reduced morbidity and mortality rates of the heparin-induced thrombocytopenia syndrome.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Autoimmune Diseases; Blood Plat | 1998 |
Development and practical use of the new quantitative bleeding time test apparatus.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bleeding Time; Case-Control Stu | 1998 |
Prevention of thrombosis and enhancement of thrombolysis in rabbits by SR 121787, a glycoprotein II/III antagonist.
Topics: Animals; Aspirin; Benzylamines; Bleeding Time; Carotid Artery Injuries; Collagen; Fibrinolytic Agent | 1998 |
Effect of glycoprotein IIb-IIIa receptor antagonism on platelet membrane glycoproteins after coronary stent placement.
Topics: Abciximab; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; | 1998 |
-Neonatal Kasabach-Merritt syndrome healed by complete surgical excision of the angioma-.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Back; Glucocorticoids; Hemangioma; Humans; Infant, | 1998 |
Thromboembolic prophylaxis with danaparoïd (Orgaran) in a high-thrombosis-risk pregnant woman with a history of heparin-induced thrombocytopenia (HIT) and Widal's disease.
Topics: Adult; Anticoagulants; Aspirin; Asthma; Cephalosporins; Chondroitin Sulfates; Dermatan Sulfate; Drug | 2000 |
Coexistence of factor V Leiden and primary antiphospholipid syndrome: a patient with recurrent myocardial infarctions and thrombocytopenia.
Topics: Activated Protein C Resistance; Anticoagulants; Antiphospholipid Syndrome; Aspirin; Blood Coagulatio | 2000 |
Correction of thrombocytopenia with aspirin in the primary antiphospholipid syndrome.
Topics: Antiphospholipid Syndrome; Aspirin; Female; Humans; Middle Aged; Platelet Count; Thrombocytopenia | 2001 |
Measurement of primary haemostasis using a pressure clamp technique.
Topics: Aspirin; Bleeding Time; Blood Platelets; Bone Marrow Diseases; Capillaries; Female; Hematocrit; Hema | 2001 |
May-hegglin anomaly: the role of aspirin in the treatment of this rare platelet disorder in pregnancy.
Topics: Adult; Aspirin; Female; Humans; Inclusion Bodies; Platelet Aggregation Inhibitors; Pregnancy; Pregna | 2002 |
Danaparoid thromboprophylaxis in pregnant women with heparin-induced thrombocytopenia.
Topics: Adult; Anticoagulants; Antithrombin III; Aspirin; Chondroitin Sulfates; Dermatan Sulfate; Drug Combi | 2002 |
Preparation and storage of platelet concentrates. II. Storage variables influencing platelet viability and function.
Topics: Aspirin; Blood Cell Count; Blood Coagulation Tests; Blood Glucose; Blood Platelets; Blood Preservati | 1976 |
[Infantile thrombopenias and drugs].
Topics: Anti-Bacterial Agents; Antimalarials; Aspirin; Child; Child, Preschool; Drug-Related Side Effects an | 1978 |
The possible role of vasoactive substances for the hemodynamic effects of rapidly injected antilymphocyte globulin.
Topics: Anaphylaxis; Animals; Antilymphocyte Serum; Aspirin; Blood Cell Count; Blood Platelets; Dogs; Hemody | 1977 |
Aspirin for the treatment of recurrent toxaemia.
Topics: Adult; Aspirin; Female; Humans; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Third; Recurrence; Th | 1978 |
Drug-induced haematological disease.
Topics: Anemia; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Aspirin; Bone Marrow Diseases; Hemato | 1979 |
Hemostatic defect in endoscoped upper gut bleeding.
Topics: Alcoholism; Aspirin; Blood Coagulation Tests; Gastritis; Gastrointestinal Hemorrhage; Humans; Liver | 1978 |
[Thrombocyte function and its disorders].
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Aspirin; Blood Platelet Disorders; Blood Platelets; | 1979 |
Normal prostacyclin-like activity in vascular tissues from thrombocytopenic rats.
Topics: Animals; Aorta, Abdominal; Arteries; Aspirin; Blood Cell Count; Blood Platelets; Epoprostenol; Prost | 1977 |
Shortening of the bleeding time in thrombocytopenic rabbits after exposure of jugular vein to high aspirin concentration.
Topics: Animals; Aspirin; Bleeding Time; Epoprostenol; Female; Jugular Veins; Male; Rabbits; Thrombocytopeni | 1979 |
An in vitro measurement of bleeding time.
Topics: Aspirin; Blood Coagulation; Blood Coagulation Tests; Citrates; Edetic Acid; Factor VIII; Heparin; Hu | 1977 |
Bleeding time in laboratory animals. III - Do tail bleeding times in rats only measure a platelet defect? (the aspirin puzzle).
Topics: Animals; Aspirin; Bleeding Time; Blood Coagulation; Blood Platelets; Male; Malondialdehyde; Morpholi | 1979 |
The influence of drugs on disseminated intravascular coagulation (dic). III. Effects of busulfan-induced thrombocytopenia and inhibition of platelet function by acetylsalicylic acid.
Topics: Animals; Aspirin; Busulfan; Disseminated Intravascular Coagulation; Fibrinogen; Male; Platelet Aggre | 1979 |
The role of platelets in the hypotensive effect of carrageenans in the rat.
Topics: Animals; Aspirin; Blood Platelets; Blood Pressure; Carrageenan; Depression, Chemical; Rats; Thromboc | 1979 |
Interactions of immune complexes and platelets in rabbits immunized with hapten-carrier conjugates.
Topics: Animals; Antibody Formation; Antigen-Antibody Complex; Antigens; Aspirin; Blood Platelets; Dose-Resp | 1977 |
Platelet effects of arachidonic acid in dog blood. I. Lack of involvement of cyclo-oxygenase in the in vivo situation.
Topics: Adenosine Diphosphate; Ancrod; Animals; Arachidonic Acids; Aspirin; Blood Platelets; Dogs; Dose-Resp | 1977 |
Platelet effects of arachidonic acid in dog blood. II. Involvement of cyclo-oxygenase in the in vitro situation.
Topics: Animals; Arachidonic Acids; Aspirin; Blood Platelets; Dogs; Drug Interactions; Erythrocytes; Ethanol | 1977 |
The effect of ALG on coagulation and fibrinolysis.
Topics: Animals; Antilymphocyte Serum; Aspirin; Blood Cell Count; Blood Coagulation; Blood Platelets; Dogs; | 1978 |
Thrombocytopenic reaction to aspirin and acetaminophen.
Topics: Acetaminophen; Adult; Aspirin; Humans; Male; Thrombocytopenia | 1979 |
Salicylic acid prevents inhibition by aspirin of arachidonic acid-induced hypotension, bronchoconstriction and thrombocytopenia [proceedings].
Topics: Animals; Arachidonic Acids; Aspirin; Blood Pressure; Bronchi; Guinea Pigs; In Vitro Techniques; Rabb | 1977 |
[Allergic thrombocytopenia].
Topics: Adult; Aspirin; Bites and Stings; Female; Humans; Male; Middle Aged; Skin Tests; Thrombocytopenia; V | 1977 |
Thrombotic thrombocytopenic purpura in a previously splenectomized patient.
Topics: Adult; Aspirin; Dipyridamole; Humans; Male; Prednisone; Spleen; Splenectomy; Thrombocytopenia | 1976 |
The bleeding time as a test of hemostatic function.
Topics: Aspirin; Blood Coagulation; Blood Coagulation Disorders; Blood Coagulation Factors; Blood Coagulatio | 1975 |
Drugs affecting platelet function tests: their effects on haemostasis and surgical bleeding.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Coagulation Disorders; Blood Donors; Blood P | 1975 |
Preliminary report: treatment of the hemolytic-uremic syndrome with aspirin and dipyridamole.
Topics: Acute Disease; Anemia, Hemolytic; Aspirin; Blood Platelet Disorders; Blood Platelets; Blood Transfus | 1975 |
Editorial: Platelet-function tests: predictive value.
Topics: Aspirin; Blood Platelets; Cell Survival; Humans; Lipids; Methods; Peroxides; Platelet Aggregation; P | 1975 |
Intravascular coagulation in acute lupus erythematosus.
Topics: Acute Disease; Adult; Aspirin; Disseminated Intravascular Coagulation; Female; Headache; Hemolysis; | 1975 |
The effect of thrombocytopenia on the determination of platelet aggregation.
Topics: Adenosine Diphosphate; Adult; Aspirin; Collagen; Epinephrine; Humans; Platelet Aggregation; Thromboc | 1976 |
Aspirin-ticlopidin in Kasabach-Merritt syndrome.
Topics: Aspirin; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Hemangioma; Humans; Infant; Thr | 1992 |
[Kasabach-Merritt syndrome in children].
Topics: Aspirin; Child, Preschool; Disseminated Intravascular Coagulation; Embolization, Therapeutic; Hemang | 1992 |
Preparation and thrombogenicity of alkylated polyvinyl alcohol coated tubing.
Topics: Adsorption; Alkylation; Animals; Arteriovenous Shunt, Surgical; Aspirin; Biocompatible Materials; Do | 1992 |
Heparin-induced thrombocytopenia in renal failure.
Topics: Adult; Aspirin; Catheterization, Central Venous; Female; Heparin; Humans; Kidney Failure, Chronic; N | 1992 |
Contribution of platelet thromboxane production to enhanced urinary excretion and glomerular production of thromboxane and to the pathogenesis of albuminuria in the streptozotocin-diabetic rat.
Topics: Albuminuria; Animals; Aspirin; Blood Platelets; Diabetes Mellitus, Experimental; Dinoprostone; Femal | 1992 |
Multiple complications of the antiphospholipid syndrome with apparent response to aspirin therapy.
Topics: Adult; Anemia, Hemolytic; Antiphospholipid Syndrome; Aspirin; Cyclophosphamide; Dose-Response Relati | 1992 |
[Heparin-associated thrombocytopenia, thrombosis and embolism. Side effects of thromboembolism prevention with low molecular weight heparin enoxaparin?].
Topics: Aged; Aspirin; Blood Coagulation Tests; Carcinoma, Renal Cell; Heparin, Low-Molecular-Weight; Humans | 1991 |
Intraoperative management of patients with heparin-induced thrombocytopenia.
Topics: Adult; Aged; Aspirin; beta-Thromboglobulin; Bleeding Time; Epoprostenol; Fibrinopeptide A; Heparin; | 1990 |
Usefulness of antiplatelet drugs in the management of heparin-associated thrombocytopenia and thrombosis.
Topics: Aged; Aorta, Abdominal; Aspirin; Dipyridamole; Female; Femoral Vein; Heparin; Humans; Iliac Artery; | 1991 |
Dysarthria and a numb hand in an elderly woman.
Topics: Aged; Aspirin; Cerebral Infarction; Dysarthria; Female; Hand; Hematoma, Subdural; Humans; Paresthesi | 1992 |
The role of platelets in the reflex tachypnoeic response to miliary pulmonary embolism in anaesthetized rabbits.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Blood Pressure; Immune S | 1990 |
Prolongation of premature gestation in women with hemolysis, elevated liver enzymes and low platelets. A report of five cases.
Topics: Adrenal Cortex Hormones; Adult; Aspirin; Female; Hemolysis; Humans; Hypertension; Liver; Pregnancy; | 1990 |
Heparin-induced platelet activation in sixteen surgical patients: diagnosis and management.
Topics: Adult; Aged; Aspirin; Epoprostenol; Female; Heparin; Humans; Iloprost; Male; Middle Aged; Platelet A | 1987 |
Plasmapheresis in the management of heparin-associated thrombocytopenia with thrombosis.
Topics: Amputation, Surgical; Aspirin; Dextrans; Female; Heparin; Humans; Intermittent Claudication; Ischemi | 1988 |
Platelet aggregating activity in the plasma of patients with established thrombosis.
Topics: Adult; Aged; Aspirin; Benzamidines; Blood Coagulation Factors; Edetic Acid; Humans; Middle Aged; Pla | 1989 |
Effect of a novel thromboxane A2 receptor antagonist, S-145, on collagen-induced ECG changes and thrombocytopenia in rodents.
Topics: Administration, Oral; Animals; Aspirin; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Collagen; | 1989 |
[Hematoma of the psoas as the only hemorrhagic manifestation in an immune thrombocytopenia associated with chronic lymphatic leukemia].
Topics: Aspirin; Hematoma; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Thrombocytopen | 1989 |
Effect of aspirin on heparin-induced thrombocytopenia (HIT) in a patient requiring hemodialysis.
Topics: Aged; Aspirin; Blood Platelets; Heparin; Humans; Immunoglobulin G; Kidney Failure, Chronic; Male; Re | 1989 |
Correction of thrombocytopenia with small dose aspirin in the primary antiphospholipid syndrome.
Topics: Adolescent; Adult; Antibodies; Aspirin; Drug Administration Schedule; Female; Humans; Male; Phosphol | 1989 |
Clinical application of a new in vitro bleeding time device on surgical patients.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aspirin; Bleeding Time; Epoprostenol; Hemorrhage; Hemostasis; H | 1988 |
Platelet-activating factor and the release of a platelet-derived coronary artery vasodilator substance in the canine.
Topics: Animals; Aspirin; Coronary Circulation; Coronary Vessels; Diphenhydramine; Dogs; Histamine H1 Antago | 1986 |
Thrombocytopenia associated with pregnancy in a patient with type IIB von Willebrand's disease.
Topics: Adult; Aspirin; Blood Coagulation Tests; Bucladesine; Epoprostenol; Female; Humans; Platelet Aggrega | 1987 |
Dazoxiben, UK 38,485 and aspirin: duration of effect for preventing thrombotic sudden death in rabbits.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Imidazoles; Mal | 1986 |
Thrombocytopenia: a complication of Kawasaki disease.
Topics: Aspirin; Child; Child, Preschool; Coronary Aneurysm; Female; Flurbiprofen; Humans; Infant; Male; Med | 1988 |
Management of patients with heparin-associated thrombocytopenia and thrombosis requiring cardiac surgery.
Topics: Adult; Aged; Aspirin; Cardiopulmonary Bypass; Coronary Artery Bypass; Dipyridamole; Emergencies; Fem | 1987 |
Buccal mucosa bleeding times of healthy dogs and of dogs in various pathologic states, including thrombocytopenia, uremia, and von Willebrand's disease.
Topics: Animals; Aspirin; Bleeding Time; Blood Coagulation Tests; Dog Diseases; Dogs; Mouth Mucosa; Thromboc | 1987 |
Heparin-induced thrombocytopenia platelet aggregation studies in the presence of heparin fractions or semi-synthetic analogues of various molecular weights and anticoagulant activities.
Topics: Adenosine; Aged; Aspirin; Epoprostenol; Heparin; Humans; In Vitro Techniques; Male; Molecular Weight | 1986 |
Hemostatic effects of microfibrillar collagen hemostat (MCH) in experimental coagulopathy model and its mechanism of hemostasis.
Topics: Animals; Aspirin; Blood Coagulation Disorders; Cattle; Collagen; Dogs; Hemorrhage; Hemostatic Techni | 1986 |
The thrombopenic effect of ellagic acid in the rat. Another model of platelet stimulation "in vivo".
Topics: Animals; Aspirin; Benzopyrans; Blood Platelets; Disease Models, Animal; Ellagic Acid; Female; Fibrin | 1987 |
Interactions between local inflammatory and systemic haematological effects of PAF-acether in the rat.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dexamethasone; Edema; Indomethacin; Inflammation; Male; | 1987 |
Biochemical and pharmacological studies on the interaction of PK 10169 and its subfractions with human platelets.
Topics: Antithrombin III; Aspirin; Factor X; Factor Xa; Heparin; Humans; Molecular Weight; Platelet Aggregat | 1986 |
"Haemostasis time", a modified bleeding time test and its comparison with the Duke and Ivy/template bleeding times. I. Normal values, application in thrombocytopenic patients and evaluation of heparin and aspirin effects.
Topics: Adolescent; Adult; Aspirin; Bleeding Time; Catheterization; Child; Female; Hemostasis; Heparin; Huma | 1986 |
Heparin-associated thrombocytopenia and thrombosis: a serious clinical problem and potential solution.
Topics: Aspirin; Female; Heparin; Humans; In Vitro Techniques; Male; Platelet Aggregation; Thrombocytopenia; | 1986 |
Heparin-induced thrombocytopenia: further studies of the effects of heparin-dependent antibodies on platelets.
Topics: Adenosine Diphosphate; Antibodies; Aspirin; Bernard-Soulier Syndrome; Dipyridamole; Heparin; Humans; | 1986 |
Femoral artery laceration complicating an intertrochanteric hip fracture: a multi-disciplinary therapeutic problem.
Topics: Aged; Aspirin; Embolization, Therapeutic; Female; Femoral Artery; Hematoma; Hip Fractures; Humans; O | 1985 |
Nasal packing with porcine fatty tissue for epistaxis complicated by qualitative platelet disorders.
Topics: Adipose Tissue; Aged; Animals; Aspirin; Epistaxis; Female; Hemostatic Techniques; Humans; Male; Midd | 1985 |
Letter: Heparin thrombin clotting-time and platelet factor 4.
Topics: Adult; Arteriosclerosis; Aspirin; Blood Coagulation; Blood Coagulation Factors; Blood Coagulation Te | 1974 |
Aspirin and prednisone in microangiopathic haemolytic anaemia.
Topics: Adult; Anemia, Hemolytic; Aspirin; Blood Platelet Disorders; Blood Urea Nitrogen; Erythrocytes, Abno | 1970 |
Platelet retention in glass bead columns: further evidence for the importance of ADP.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Aspirin; Blood Platelet Di | 1974 |
Decreased ATP, ADP and serotonin in young platelets of fawn-hooded rats with storage pool disease.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aspirin; Blood Platelet | 1974 |
Platelet disorders.
Topics: Antibody Formation; Aspirin; Blood Cell Count; Blood Coagulation Disorders; Blood Coagulation Tests; | 1972 |
Platelet function abnormalities in the myeloproliferative disorders.
Topics: Adenosine Diphosphate; Adult; Aged; Aspirin; Blood Cell Count; Blood Platelets; Collagen; Epinephrin | 1974 |
The bleeding time as a screening test for evaluation of platelet function.
Topics: Adult; Aspirin; Blood Cell Count; Blood Coagulation Tests; Blood Platelet Disorders; Blood Platelets | 1972 |
Mechanism of action of some anti-rheumatic drugs in allergic blood diseases.
Topics: Aspirin; Cell Membrane; Drug Hypersensitivity; Humans; Thrombocytopenia | 1973 |
Studies of platelet concentrates stored at 22 C nad 4 C.
Topics: Aspirin; Blood Coagulation Tests; Blood Platelets; Blood Preservation; Blood Transfusion; Cell Survi | 1973 |
[Animal experiment studies on the inhibition of platelet aggregation by verapamil in vitro and in vivo].
Topics: Adenosine Diphosphate; Animals; Aspirin; Depression, Chemical; Dipyridamole; Dogs; Fatty Acids; Huma | 1973 |
Platelet-tumor-cell interactions in mice. The role of platelets in the spread of malignant disease.
Topics: Adenocarcinoma; Animals; Aspirin; Blood Cell Count; Blood Platelets; Carcinoma; Cell Survival; Chrom | 1973 |
Drug-induced bleeding.
Topics: Acetaminophen; Anemia, Aplastic; Anticoagulants; Aspirin; Blood Platelets; Bone Marrow; Capillary Fr | 1974 |
A method for demonstrating shortened platelet survival utilizing recovery from aspirin effect.
Topics: Aspirin; Blood Cell Count; Blood Platelets; Cell Survival; Humans; Platelet Adhesiveness; Purpura, T | 1974 |
Aspirin-induced thrombocytopenia on an immune basis.
Topics: Aged; Antibodies; Aspirin; Blood Cell Count; Blood Platelets; Drug Hypersensitivity; Humans; Male; P | 1974 |
Bleeding disorders during surgery.
Topics: Adrenal Cortex Hormones; Aspirin; Blood Coagulation Disorders; Blood Coagulation Factors; Blood Coag | 1974 |
Aggregation of human platelets by commercial preparations of bovine and porcine antihaemophilic globulin.
Topics: Adenosine; Animals; Aspirin; Blood Cell Count; Cattle; Densitometry; Factor VIII; Fibrinogen; Goats; | 1972 |
Platelet function in recipients of platelets from donors ingesting aspirin.
Topics: Administration, Oral; Aspirin; Blood Cell Count; Blood Coagulation; Blood Coagulation Tests; Blood D | 1972 |
[Diseases of the gingiva, oral mucosa and lips].
Topics: Aspirin; Dentistry; Gingival Diseases; Lichen Planus; Lip; Mouth Diseases; Periodontal Diseases; Thr | 1968 |
The vascular component in hemostasis.
Topics: Adult; Aged; Aspirin; Blood Coagulation Tests; Blood Vessels; Female; Hemorrhagic Disorders; Hemosta | 1970 |
Platelet response to induction of hemorrhagic pancreatitis.
Topics: Animals; Anti-Bacterial Agents; Aspirin; Blood Cell Count; Dipyridamole; Disease Models, Animal; Dog | 1971 |