Page last updated: 2024-10-23

aspirin and Teeth, Impacted

aspirin has been researched along with Teeth, Impacted in 35 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
"This case report discusses enucleation of a central dentigerous cyst in a 72-year old male on long-term low dose aspirin therapy."3.78Management of a dentigerous cyst in a medically compromised geriatric patient: a case report. ( Bains, R; Bains, VK; Loomba, A; Loomba, K, 2012)
" There were no significant differences between treatment groups with respect to the number of patients requiring rescue medication, however the time to dosing was significantly longer for those taking soluble aspirin when compared with placebo (hazard ratio 2."2.71An investigation into the comparative efficacy of soluble aspirin and solid paracetamol in postoperative pain after third molar surgery. ( Hawkesford, JE; Hill, CM; Seymour, RA; Stillings, M; Sykes, J, 2003)
" The slope of the dose-response curve of bromfenac was significant."2.67Analgesic efficacy of bromfenac, ibuprofen, and aspirin in postoperative oral surgery pain. ( Beaver, WT; Edquist, IA; Forbes, JA; Gongloff, CM; Jones, KF; Schwartz, MK; Smith, FG; Smith, WK, 1992)
" All active treatments were significantly superior to placebo, and the slope of the dose-response curve for bromfenac was significant."2.67Evaluation of bromfenac, aspirin, and ibuprofen in postoperative oral surgery pain. ( Beaver, WT; Edquist, IA; Forbes, JA; Schwartz, MK; Smith, FG, 1991)
"Aspirin 1200 mg was compared with placebo in a randomised, double-blind, crossover study in 15 patients with postoperative pain after removal of impacted lower third molars."2.65Aspirin metabolism and efficacy in postoperative dental pain. ( Rawlins, MD; Seymour, RA; Ward, A; Williams, FM, 1984)
" Each dosage level of proquazone and aspirin provided significant analgesia compared to placebo and was well tolerated."2.65An evaluation of the analgesic efficacy of proquazone and aspirin in postoperative dental pain. ( Forbes, JA; Hughes, MK; White, EH; White, RW, 1980)
"Mefenamic acid was clearly superior to placebo and equalled or exceeded the ability of aspirin to control postsurgical pain in the parameters measured."2.65Control of pain by mefenamic acid following removal of impacted molar. A double-blind, placebo-controlled study. ( Cudmore, CL; Rowe, NH; Turner, JL, 1981)
" Time-effect and dose-response curves were generated from the relief and change in pain-intensity scores."2.64Comparative analgesic potency of aspirin and ibuprofen. ( Cooper, SA; Kruger, GO; Needle, SE, 1977)
"Ibuprofen 400 mg was consistently more effective than aspirin 650 mg, acetaminophen 600 mg, and both aspirin and acetaminophen when combined with codeine 60 mg."1.27Five studies on ibuprofen for postsurgical dental pain. ( Cooper, SA, 1984)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199023 (65.71)18.7374
1990's7 (20.00)18.2507
2000's1 (2.86)29.6817
2010's4 (11.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Voelker, M2
Schachtel, BP1
Cooper, SA6
Gatoulis, SC1
Morimoto, Y1
Niwa, H1
Nakatani, T1
Loomba, A1
Loomba, K1
Bains, R1
Bains, VK1
Seymour, RA3
Hawkesford, JE1
Sykes, J1
Stillings, M1
Hill, CM1
Desjardins, PJ1
Gallegos, TL1
Allwein, JB1
Reynolds, DC1
Kruger, GO2
Beaver, WT4
Williams, FM1
Ward, A1
Rawlins, MD1
Forbes, JA4
White, RW1
White, EH1
Hughes, MK1
Rowe, NH2
Cudmore, CL1
Turner, JL3
Ihalainen, U1
Rissanen, H1
Oikarinen, VJ1
Bailey, BM1
Zaki, G1
Rotman, H1
Woodwards, RT1
Petersen, JK2
Hellem, S1
Persson, G1
Freiberg, N1
Nord, PG1
Gustafsson, B1
Huitfeldt, B1
Needle, SE1
Henrikson, PA1
Tjernberg, A1
Ahlström, U3
Peterson, LE1
Dionne, RA1
Sveen, K1
Gilhuus-Moe, O1
Hellman, M1
Andersson, L1
Strid, S1
Jones, KF1
Edquist, IA2
Gongloff, CM1
Smith, WK1
Smith, FG2
Schwartz, MK2
Butterworth, GA1
Burchfield, WH1
Habib, S1
Matthews, RW1
Scully, C1
Levers, BG1
Shepherd, JP1
Gallardo, F2
Carstens, M2
Ayarza, M1
Frame, JW1
Fisher, SE1
Pickvance, NJ1
Skene, AM1
Dupuis, R1
Lemay, H1
Bushnell, MC1
Duncan, GH1
Sindet-Pedersen, S1
Gøtzsche, PC1
Christensen, H1
Ligueros, O1
Lobo, R1
Pauz, M1
Happonen, RP1
Oksala, E1
Ylipaavalniemi, P1
Markowitz, NR1
Young, SK1
Rohrer, MD1
Aseltine, LF1
Dahl, E1
Feldmann, G1
Jönsson, E1
Lantz, B1
Popkes, DL1
Folsom, TC1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Onset of Action of a Fast Release Aspirin Tablet and Acetaminophen Caplet in Sore Throat Pain[NCT01453400]Phase 3177 participants (Actual)Interventional2011-09-27Completed
Comparative Onset of Action of a Fast Release Aspirin Tablet in a Dental Impaction Pain Model[NCT01420094]Phase 3510 participants (Actual)Interventional2011-06-16Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

31 trials available for aspirin and Teeth, Impacted

ArticleYear
Efficacy of disintegrating aspirin in two different models for acute mild-to-moderate pain: sore throat pain and dental pain.
    Inflammopharmacology, 2016, Volume: 24, Issue:1

    Topics: Acetaminophen; Acute Pain; Adolescent; Analgesics, Non-Narcotic; Aspirin; Double-Blind Method; Femal

2016
Efficacy of disintegrating aspirin in two different models for acute mild-to-moderate pain: sore throat pain and dental pain.
    Inflammopharmacology, 2016, Volume: 24, Issue:1

    Topics: Acetaminophen; Acute Pain; Adolescent; Analgesics, Non-Narcotic; Aspirin; Double-Blind Method; Femal

2016
Efficacy of disintegrating aspirin in two different models for acute mild-to-moderate pain: sore throat pain and dental pain.
    Inflammopharmacology, 2016, Volume: 24, Issue:1

    Topics: Acetaminophen; Acute Pain; Adolescent; Analgesics, Non-Narcotic; Aspirin; Double-Blind Method; Femal

2016
Efficacy of disintegrating aspirin in two different models for acute mild-to-moderate pain: sore throat pain and dental pain.
    Inflammopharmacology, 2016, Volume: 24, Issue:1

    Topics: Acetaminophen; Acute Pain; Adolescent; Analgesics, Non-Narcotic; Aspirin; Double-Blind Method; Femal

2016
Evaluation of onset of pain relief from micronized aspirin in a dental pain model.
    Inflammopharmacology, 2012, Volume: 20, Issue:4

    Topics: Adult; Aspirin; Chemistry, Pharmaceutical; Double-Blind Method; Female; Humans; Male; Tablets; Tooth

2012
An investigation into the comparative efficacy of soluble aspirin and solid paracetamol in postoperative pain after third molar surgery.
    British dental journal, 2003, Feb-08, Volume: 194, Issue:3

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analysis of Variance; Anti-Inflammatory Agents, Non-

2003
The relative analgesic efficacy of propiram fumarate, codeine, aspirin, and placebo in post-impaction dental pain.
    Journal of clinical pharmacology, 1984, Volume: 24, Issue:1

    Topics: Adolescent; Adult; Aged; Analgesics; Aspirin; Clinical Trials as Topic; Codeine; Female; Humans; Mal

1984
Aspirin metabolism and efficacy in postoperative dental pain.
    British journal of clinical pharmacology, 1984, Volume: 17, Issue:6

    Topics: Adolescent; Adult; Aspirin; Carboxylic Ester Hydrolases; Clinical Trials as Topic; Double-Blind Meth

1984
An evaluation of the analgesic efficacy of proquazone and aspirin in postoperative dental pain.
    Journal of clinical pharmacology, 1980, Volume: 20, Issue:7

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic;

1980
Control of pain by mefenamic acid following removal of impacted molar. A double-blind, placebo-controlled study.
    Oral surgery, oral medicine, and oral pathology, 1981, Volume: 51, Issue:6

    Topics: Adolescent; Adult; Aged; Aspirin; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Mal

1981
The efficacy and tolerability of diflunisal and ASA in the relief of postoperative pain in oral surgery.
    Proceedings of the Finnish Dental Society. Suomen Hammaslaakariseuran toimituksia, 1980, Volume: 76, Issue:5-6

    Topics: Adolescent; Adult; Aspirin; Clinical Trials as Topic; Diflunisal; Female; Humans; Male; Middle Aged;

1980
The use of pain scales in assessing the efficacy of analgesics in post-operative dental pain.
    European journal of clinical pharmacology, 1982, Volume: 23, Issue:5

    Topics: Adult; Analgesics; Aspirin; Double-Blind Method; Female; Humans; Male; Pain; Pain, Postoperative; To

1982
A double-blind comparative study of soluble aspirin and diclofenac dispersible in the control of postextraction pain after removal of impacted third molars.
    International journal of oral and maxillofacial surgery, 1993, Volume: 22, Issue:4

    Topics: Adolescent; Adult; Aspirin; Diclofenac; Double-Blind Method; Female; Humans; Male; Molar, Third; Pai

1993
Diflunisal, a new analgesic, in the treatment of postoperative pain following removal of impacted mandibular third molars.
    International journal of oral surgery, 1979, Volume: 8, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemical

1979
A model for evaluating the analgesic effect of a new fixed ratio combination analgesic in patients undergoing oral surgery.
    International journal of oral surgery, 1979, Volume: 8, Issue:6

    Topics: Adult; Analgesics; Antipyrine; Aspirin; Caffeine; Dextropropoxyphene; Drug Combinations; Drug Evalua

1979
Comparative analgesic potency of aspirin and ibuprofen.
    Journal of oral surgery (American Dental Association : 1965), 1977, Volume: 35, Issue:11

    Topics: Analgesics; Aspirin; Drug Evaluation; Humans; Ibuprofen; Pain, Postoperative; Placebos; Tooth, Impac

1977
Analgesic efficacy and safety of Fenbufen following surgical removal of a lower wisdom tooth: a comparison with acetylsalicylic acid and placebo.
    The Journal of international medical research, 1979, Volume: 7, Issue:2

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biphenyl Compounds; Double-Blind Meth

1979
Evaluation of preoperative ibuprofen for postoperative pain after removal of third molars.
    Oral surgery, oral medicine, and oral pathology, 1978, Volume: 45, Issue:6

    Topics: Adolescent; Adult; Aspirin; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Drug Int

1978
Paracetamol/codeine in relieving pain following removal of impacted mandibular third molars.
    International journal of oral surgery, 1975, Volume: 4, Issue:6

    Topics: Acetaminophen; Adolescent; Adult; Aspirin; Codeine; Drug Therapy, Combination; Edema; Female; Humans

1975
Analgesic efficacy of an ibuprofen-codeine combination in patients with pain after removal of lower third molars.
    European journal of clinical pharmacology, 1992, Volume: 43, Issue:4

    Topics: Adolescent; Adult; Analgesia; Aspirin; Codeine; Double-Blind Method; Drug Combinations; Female; Huma

1992
Analgesic efficacy of bromfenac, ibuprofen, and aspirin in postoperative oral surgery pain.
    Clinical pharmacology and therapeutics, 1992, Volume: 51, Issue:3

    Topics: Aspirin; Benzophenones; Bromobenzenes; Dose-Response Relationship, Drug; Double-Blind Method; Humans

1992
Evaluation of bromfenac, aspirin, and ibuprofen in postoperative oral surgery pain.
    Pharmacotherapy, 1991, Volume: 11, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Analgesics; Aspirin; Benzophenones; Bromobenzenes; Dose-Res

1991
Evaluation of ketorolac, aspirin, and an acetaminophen-codeine combination in postoperative oral surgery pain.
    Pharmacotherapy, 1990, Volume: 10, Issue:6 ( Pt 2)

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Asp

1990
A study of the comparative efficacy of four common analgesics in the control of postsurgical dental pain.
    Oral surgery, oral medicine, and oral pathology, 1990, Volume: 70, Issue:5

    Topics: Acetaminophen; Adult; Analgesics; Analysis of Variance; Aspirin; Caffeine; Codeine; Drug Combination

1990
Analgesic and antiinflammatory effects of glucamethacin (a nonsteroidal antiinflammatory analgesic) after the removal of impacted third molars.
    Oral surgery, oral medicine, and oral pathology, 1990, Volume: 69, Issue:2

    Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chi-Square Distribution; Double

1990
A double-blind placebo-controlled comparison of three ibuprofen/codeine combinations and aspirin.
    The British journal of oral & maxillofacial surgery, 1986, Volume: 24, Issue:2

    Topics: Aspirin; Clinical Trials as Topic; Codeine; Double-Blind Method; Drug Combinations; Humans; Ibuprofe

1986
Preoperative flurbiprofen in oral surgery: a method of choice in controlling postoperative pain.
    Pharmacotherapy, 1988, Volume: 8, Issue:3

    Topics: Adult; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Drug Combinations; Female; Flurbiprofen

1988
A double-blind, randomized study of naproxen and acetylsalicylic acid after surgical removal of impacted lower third molars.
    International journal of oral and maxillofacial surgery, 1986, Volume: 15, Issue:4

    Topics: Adolescent; Adult; Aged; Aspirin; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Mal

1986
[Comparative, double blind study of the analgesic and anti-inflammatory activity of glucamethacin (Indicin), aspirin and placebo in oral surgery].
    Odontologia chilena, 1987, Volume: 35, Issue:1

    Topics: Adult; Aspirin; Double-Blind Method; Female; Humans; Indomethacin; Male; Molar, Third; Pain, Postope

1987
A combination of acetylsalicylic acid and codeine phosphate versus acetylsalicylic acid as postoperative analgesics after mandibular third molar surgery.
    Proceedings of the Finnish Dental Society. Suomen Hammaslaakariseuran toimituksia, 1987, Volume: 83, Issue:1

    Topics: Adult; Aspirin; Codeine; Double-Blind Method; Drug Combinations; Female; Humans; Male; Molar, Third;

1987
Comparison of meclofenamate sodium with buffered aspirin and placebo in the treatment of postsurgical dental pain.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1985, Volume: 43, Issue:7

    Topics: Acetaminophen; Adolescent; Adult; Aged; Aspirin; Codeine; Female; Humans; Male; Meclofenamic Acid; M

1985
Control of pain with meclofenamate sodium following removal of an impacted molar.
    Oral surgery, oral medicine, and oral pathology, 1985, Volume: 59, Issue:5

    Topics: Adolescent; Adult; Aspirin; Clinical Trials as Topic; Double-Blind Method; Drug Administration Sched

1985
Acetylsalicylic acid compared with acetylsalicylic acid plus codeine as postoperative analgesics after removal of impacted mandibular third molars.
    Swedish dental journal, 1985, Volume: 9, Issue:5

    Topics: Adolescent; Adult; Aspirin; Clinical Trials as Topic; Codeine; Double-Blind Method; Drug Combination

1985
A comparison between dextro propoxyphene hydrochloride and acetyl salicylic acid as analgesics after oral surgery.
    Odontologisk revy, 1968, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Aspirin; Dextropropoxyphene; Female; Humans; Male; Middle Aged; Pain; Placebos; P

1968

Other Studies

4 other studies available for aspirin and Teeth, Impacted

ArticleYear
On the use of prothrombin complex concentrate in patients with coagulopathy requiring tooth extraction.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2010, Volume: 110, Issue:6

    Topics: Adult; Aspirin; Blood Coagulation Factors; Blood Loss, Surgical; Cellulose, Oxidized; Contraindicati

2010
Management of a dentigerous cyst in a medically compromised geriatric patient: a case report.
    Gerodontology, 2012, Volume: 29, Issue:2

    Topics: Aged; Anesthetics, Local; Antifibrinolytic Agents; Aspirin; Bicuspid; Dental Care for Chronically Il

2012
Five studies on ibuprofen for postsurgical dental pain.
    The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A

    Topics: Acetaminophen; Adolescent; Adult; Analgesics; Aspirin; Codeine; Drug Combinations; Female; Humans; I

1984
Comparative study of three analgesic agents used in oral surgical procedures.
    Journal of oral surgery (American Dental Association : 1965), 1969, Volume: 27, Issue:12

    Topics: Adolescent; Adult; Aged; Alveoloplasty; Analgesics; Aspirin; Caffeine; Codeine; Humans; Middle Aged;

1969