aspirin has been researched along with Systemic Inflammatory Response Syndrome in 22 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Systemic Inflammatory Response Syndrome: A systemic inflammatory response to a variety of clinical insults, characterized by two or more of the following conditions: (1) fever
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study investigated the efficacy of terutroban, a specific thromboxane/prostaglandin endoperoxide receptor antagonist, on stroke incidence in spontaneously hypertensive stroke-prone rats (SHRSP)." | 7.76 | Terutroban, a thromboxane/prostaglandin endoperoxide receptor antagonist, increases survival in stroke-prone rats by preventing systemic inflammation and endothelial dysfunction: comparison with aspirin and rosuvastatin. ( Ballerio, R; Banfi, C; Blanc-Guillemaud, V; Brioschi, M; Castiglioni, L; Gelosa, P; Gianella, A; Guerrini, U; Lerond, L; Nobili, E; Pignieri, A; Sironi, L; Tremoli, E, 2010) |
| "Aspirin treatment during the ICU stay was associated with a significantly reduced 28-day all-cause mortality, particularly in patients with SIRS symptoms but without sepsis." | 4.31 | Aspirin Therapy and 28-Day Mortality in ICU Patients: A Retrospective Observational Study From Two Large Databases. ( Guan, X; Li, B; Liu, Y; Liu, Z; Nie, Y; Pei, F; Wang, L; Wu, J; Zuo, L, 2023) |
| "This study investigated the efficacy of terutroban, a specific thromboxane/prostaglandin endoperoxide receptor antagonist, on stroke incidence in spontaneously hypertensive stroke-prone rats (SHRSP)." | 3.76 | Terutroban, a thromboxane/prostaglandin endoperoxide receptor antagonist, increases survival in stroke-prone rats by preventing systemic inflammation and endothelial dysfunction: comparison with aspirin and rosuvastatin. ( Ballerio, R; Banfi, C; Blanc-Guillemaud, V; Brioschi, M; Castiglioni, L; Gelosa, P; Gianella, A; Guerrini, U; Lerond, L; Nobili, E; Pignieri, A; Sironi, L; Tremoli, E, 2010) |
| "Aspirin was commonly recommended for mild cases, whereas heparin or low molecular weight heparin were to be used primarily in severe cases." | 1.62 | Multisystem Inflammatory Syndrome in Children: Survey of Protocols for Early Hospital Evaluation and Management. ( Abuali, M; Ang, JY; Ballan, W; Basu, SK; Campbell, MJ; Chikkabyrappa, SM; Choueiter, NF; Clouser, KN; Corwin, D; Dove, ML; Edwards, A; Gertz, SJ; Ghassemzadeh, R; Jaggi, P; Jarrah, RJ; Katz, SE; Kelleman, M; Knutson, SM; Kuebler, JD; Lighter, J; Mikesell, C; Mongkolrattanothai, K; Morton, T; Nakra, NA; Olivero, R; Osborne, CM; Oster, ME; Panesar, LE; Parsons, S; Patel, RM; Schuette, J; Thacker, D; Tremoulet, AH; Vidwan, NK, 2021) |
| "As the number of coronavirus disease 2019 (COVID-19) cases increases globally, more cases of a rare COVID-19-associated disease process are being identified in the pediatric population." | 1.62 | Multisystem Inflammatory Syndrome in Children. ( Cassidy-Smith, T; Kothari, P; Tabaac, S, 2021) |
| "Patients with coronavirus disease 2019 (COVID-19) from novel coronavirus (SARS-CoV-2) infection may present with immune thrombocytopenia (ITP)." | 1.62 | Immune thrombocytopenia following multisystem inflammatory syndrome in children (MIS-C) - a case series. ( Grimes, AB; Kok, EY; Muscal, E; Sexson Tejtel, SK; Srivaths, L; Vogel, TP, 2021) |
| "BACKGROUND Coronavirus disease 2019 (COVID-19) infection commonly presents as fever, cough, and shortness of breath in adults." | 1.56 | Three Cases of Pediatric Multisystem Inflammatory Syndrome Associated with COVID-19 Due to SARS-CoV-2. ( Bauerfeld, C; Garcia, RU; Heidemann, SM; Martin, A; Sarnaik, AP; Tilford, B; Yagiela, L, 2020) |
| "We sought to determine the prevalence of acute respiratory distress syndrome after intracerebral hemorrhage, characterize risk factors for its development, and assess its impact on patient outcomes." | 1.39 | Acute respiratory distress syndrome after spontaneous intracerebral hemorrhage*. ( Avery, L; Bajwa, E; Camargo, CA; Chang, Y; Duran-Mendicuti, MA; Elmer, J; Goldstein, JN; Greenberg, SM; Hess, DR; Hou, P; Okechukwu, I; Pallin, DJ; Pontes-Neto, O; Rosand, J; Schreiber, H; Wilcox, SR, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.55) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (13.64) | 24.3611 |
| 2020's | 18 (81.82) | 2.80 |
| Authors | Studies |
|---|---|
| Ankola, AA | 1 |
| Bradford, VR | 1 |
| Newburger, JW | 1 |
| Emani, S | 1 |
| Dionne, A | 1 |
| Friedman, K | 1 |
| Son, MB | 1 |
| Henderson, LA | 1 |
| Lee, PY | 1 |
| Hellinger, A | 1 |
| Hawkins, B | 1 |
| Ventresco, C | 1 |
| Esteso, P | 1 |
| VanderPluym, CJ | 1 |
| Wang, L | 1 |
| Li, B | 1 |
| Zuo, L | 1 |
| Pei, F | 1 |
| Nie, Y | 1 |
| Liu, Y | 1 |
| Liu, Z | 1 |
| Wu, J | 1 |
| Guan, X | 1 |
| Jiang, J | 1 |
| Fan, Z | 1 |
| Mao, Y | 1 |
| Dhanalakshmi, K | 1 |
| Venkataraman, A | 1 |
| Balasubramanian, S | 1 |
| Madhusudan, M | 1 |
| Amperayani, S | 1 |
| Putilibai, S | 1 |
| Sadasivam, K | 1 |
| Ramachandran, B | 1 |
| Ramanan, AV | 1 |
| Heidemann, SM | 1 |
| Tilford, B | 1 |
| Bauerfeld, C | 1 |
| Martin, A | 1 |
| Garcia, RU | 1 |
| Yagiela, L | 1 |
| Sarnaik, AP | 1 |
| Cioccari, L | 1 |
| Luethi, N | 1 |
| Duong, T | 1 |
| Ryan, E | 1 |
| Cutuli, SL | 1 |
| Lloyd-Donald, P | 1 |
| Eastwood, GM | 1 |
| Peck, L | 1 |
| Young, H | 1 |
| Vaara, ST | 1 |
| French, CJ | 1 |
| Orford, N | 1 |
| Dwivedi, J | 1 |
| Lankadeva, YR | 1 |
| Bailey, M | 1 |
| Reid, GE | 1 |
| Bellomo, R | 1 |
| Kofman, AD | 1 |
| Sizemore, EK | 1 |
| Detelich, JF | 1 |
| Albrecht, B | 1 |
| Piantadosi, AL | 1 |
| Fernández-González, SM | 1 |
| Varela-Ferreiro, N | 1 |
| Castro Aguiar, S | 1 |
| Pardo-Vázquez, JJ | 1 |
| Dove, ML | 1 |
| Jaggi, P | 1 |
| Kelleman, M | 1 |
| Abuali, M | 1 |
| Ang, JY | 1 |
| Ballan, W | 1 |
| Basu, SK | 1 |
| Campbell, MJ | 1 |
| Chikkabyrappa, SM | 1 |
| Choueiter, NF | 1 |
| Clouser, KN | 1 |
| Corwin, D | 1 |
| Edwards, A | 1 |
| Gertz, SJ | 1 |
| Ghassemzadeh, R | 1 |
| Jarrah, RJ | 1 |
| Katz, SE | 1 |
| Knutson, SM | 1 |
| Kuebler, JD | 1 |
| Lighter, J | 1 |
| Mikesell, C | 1 |
| Mongkolrattanothai, K | 1 |
| Morton, T | 1 |
| Nakra, NA | 1 |
| Olivero, R | 1 |
| Osborne, CM | 1 |
| Panesar, LE | 1 |
| Parsons, S | 1 |
| Patel, RM | 1 |
| Schuette, J | 1 |
| Thacker, D | 1 |
| Tremoulet, AH | 1 |
| Vidwan, NK | 1 |
| Oster, ME | 1 |
| Tabaac, S | 1 |
| Kothari, P | 1 |
| Cassidy-Smith, T | 1 |
| Makiello, P | 1 |
| Svirpliene, S | 1 |
| Finlay, L | 1 |
| McKnight, J | 1 |
| Blink, M | 1 |
| Buddingh', EP | 1 |
| Filippini, LHPM | 1 |
| Brinkman, DMC | 1 |
| Joosten, SA | 1 |
| Klein, RH | 1 |
| Cherqaoui, B | 1 |
| Koné-Paut, I | 1 |
| Yager, H | 1 |
| Bourgeois, FL | 1 |
| Piram, M | 1 |
| Rayamajhi, A | 1 |
| Sharma, M | 1 |
| Deo, MK | 1 |
| Shrestha, S | 1 |
| Bista, KP | 1 |
| Paudel, KP | 1 |
| Cattalini, M | 1 |
| Della Paolera, S | 1 |
| Zunica, F | 1 |
| Bracaglia, C | 1 |
| Giangreco, M | 1 |
| Verdoni, L | 1 |
| Meini, A | 1 |
| Sottile, R | 1 |
| Caorsi, R | 1 |
| Zuccotti, G | 1 |
| Fabi, M | 1 |
| Montin, D | 1 |
| Meneghel, A | 1 |
| Consolaro, A | 1 |
| Dellepiane, RM | 1 |
| Maggio, MC | 1 |
| La Torre, F | 1 |
| Marchesi, A | 1 |
| Simonini, G | 1 |
| Villani, A | 1 |
| Cimaz, R | 1 |
| Ravelli, A | 1 |
| Taddio, A | 1 |
| Kok, EY | 1 |
| Srivaths, L | 1 |
| Grimes, AB | 1 |
| Vogel, TP | 1 |
| Sexson Tejtel, SK | 1 |
| Muscal, E | 1 |
| Kinter, CW | 1 |
| Saxon, GE | 1 |
| Ahmad, M | 1 |
| Berhane, H | 1 |
| Gensler, L | 1 |
| Khosroshahi, A | 1 |
| Gottlieb, M | 1 |
| Bridwell, R | 1 |
| Ravera, J | 1 |
| Long, B | 1 |
| Elmer, J | 1 |
| Hou, P | 1 |
| Wilcox, SR | 1 |
| Chang, Y | 1 |
| Schreiber, H | 1 |
| Okechukwu, I | 1 |
| Pontes-Neto, O | 1 |
| Bajwa, E | 1 |
| Hess, DR | 1 |
| Avery, L | 1 |
| Duran-Mendicuti, MA | 1 |
| Camargo, CA | 1 |
| Greenberg, SM | 1 |
| Rosand, J | 1 |
| Pallin, DJ | 1 |
| Goldstein, JN | 1 |
| Gelosa, P | 1 |
| Ballerio, R | 1 |
| Banfi, C | 1 |
| Nobili, E | 1 |
| Gianella, A | 1 |
| Pignieri, A | 1 |
| Brioschi, M | 1 |
| Guerrini, U | 1 |
| Castiglioni, L | 1 |
| Blanc-Guillemaud, V | 1 |
| Lerond, L | 1 |
| Tremoli, E | 1 |
| Sironi, L | 1 |
| Eisen, DP | 1 |
| Reid, D | 1 |
| McBryde, ES | 1 |
| Chalasani, N | 1 |
| Roman, J | 1 |
| Jurado, RL | 1 |
2 reviews available for aspirin and Systemic Inflammatory Response Syndrome
| Article | Year |
|---|---|
Delineating phenotypes of Kawasaki disease and SARS-CoV-2-related inflammatory multisystem syndrome: a French study and literature review.
Topics: Adolescent; Aspirin; C-Reactive Protein; Case-Control Studies; Child; Child, Preschool; Coronary Dis | 2021 |
Multisystem inflammatory syndrome in children with COVID-19.
Topics: Adolescent; Adrenal Cortex Hormones; Aspirin; Child; Child, Preschool; COVID-19; Emergency Service, | 2021 |
1 trial available for aspirin and Systemic Inflammatory Response Syndrome
| Article | Year |
|---|---|
Cytokine and lipid metabolome effects of low-dose acetylsalicylic acid in critically ill patients with systemic inflammation: a pilot, feasibility, multicentre, randomised, placebo-controlled trial.
Topics: Aspirin; Australia; Critical Illness; Cytokines; Double-Blind Method; Feasibility Studies; Humans; I | 2020 |
19 other studies available for aspirin and Systemic Inflammatory Response Syndrome
| Article | Year |
|---|---|
Coagulation profiles and viscoelastic testing in multisystem inflammatory syndrome in children.
Topics: Adolescent; Anticoagulants; Aspirin; Blood Coagulation; Blood Platelets; Child; Child, Preschool; CO | 2021 |
Aspirin Therapy and 28-Day Mortality in ICU Patients: A Retrospective Observational Study From Two Large Databases.
Topics: Aspirin; Critical Care; Humans; Intensive Care Units; Retrospective Studies; Sepsis; Systemic Inflam | 2023 |
A case of multisystem inflammatory syndrome in children: A case report.
Topics: Aspirin; Child; Child, Preschool; Connective Tissue Diseases; COVID-19; Female; Humans; Mucocutaneou | 2023 |
Epidemiological and Clinical Profile of Pediatric Inflammatory Multisystem Syndrome - Temporally Associated with SARS-CoV-2 (PIMS-TS) in Indian Children.
Topics: Adolescent; Antibodies, Monoclonal, Humanized; Aspirin; Blood Coagulation Disorders; C-Reactive Prot | 2020 |
Three Cases of Pediatric Multisystem Inflammatory Syndrome Associated with COVID-19 Due to SARS-CoV-2.
Topics: Antipyretics; Aspirin; Betacoronavirus; Child; Child, Preschool; Conjunctivitis; Coronavirus Infecti | 2020 |
A young adult with COVID-19 and multisystem inflammatory syndrome in children (MIS-C)-like illness: a case report.
Topics: Adult; Aspirin; Betacoronavirus; Coronavirus Infections; Cough; COVID-19; COVID-19 Drug Treatment; D | 2020 |
SARS-CoV-2 infection as trigger multisystem inflammatory syndrome?
Topics: Aspirin; Child, Preschool; COVID-19; COVID-19 Nucleic Acid Testing; COVID-19 Serological Testing; Fa | 2021 |
Multisystem Inflammatory Syndrome in Children: Survey of Protocols for Early Hospital Evaluation and Management.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Antirheumatic Agents; Aspirin; Child; Clini | 2021 |
Multisystem Inflammatory Syndrome in Children.
Topics: Aspirin; Child; COVID-19; COVID-19 Drug Treatment; Humans; Immunoglobulins; Male; SARS-CoV-2; System | 2021 |
Paediatric inflammatory multisystem syndrome temporally associated with COVID-19: a new virus and a new case presentation.
Topics: Adrenal Cortex Hormones; Aspirin; Child; COVID-19; COVID-19 Drug Treatment; Humans; Immunoglobulins, | 2020 |
[COVID-19-associated hyperinflammatory state in a 15-year-old female patient].
Topics: Adolescent; Anti-Inflammatory Agents; Aspirin; Cardiotonic Agents; COVID-19; COVID-19 Serological Te | 2020 |
Kawasaki Disease like Multisystem Inflammatory Syndrome in a Toddler during SARS-CoV-2 Pandemic in Nepal.
Topics: Aspirin; COVID-19; COVID-19 Drug Treatment; Humans; Immunoglobulins; Infant; Male; Nepal; Systemic I | 2021 |
Defining Kawasaki disease and pediatric inflammatory multisystem syndrome-temporally associated to SARS-CoV-2 infection during SARS-CoV-2 epidemic in Italy: results from a national, multicenter survey.
Topics: Age Distribution; Antirheumatic Agents; Aspirin; C-Reactive Protein; Child; Child, Preschool; Corona | 2021 |
Immune thrombocytopenia following multisystem inflammatory syndrome in children (MIS-C) - a case series.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; COVID-19; Disease Management; Glucocorticoi | 2021 |
Multisystem inflammatory syndrome in an adult with involvement of the skin, lymph nodes, muscle, heart, liver and kidneys.
Topics: Acute Kidney Injury; Adult; Anti-Inflammatory Agents; Aspirin; Asymptomatic Infections; Biomarkers; | 2021 |
Acute respiratory distress syndrome after spontaneous intracerebral hemorrhage*.
Topics: Acute Lung Injury; Aged; Aspirin; Cerebral Hemorrhage; Cohort Studies; Erythrocyte Transfusion; Fema | 2013 |
Terutroban, a thromboxane/prostaglandin endoperoxide receptor antagonist, increases survival in stroke-prone rats by preventing systemic inflammation and endothelial dysfunction: comparison with aspirin and rosuvastatin.
Topics: Animals; Aspirin; Biomarkers; Blood Pressure; Brain; Endothelium, Vascular; Fluorobenzenes; Hyperten | 2010 |
Acetyl salicylic acid usage and mortality in critically ill patients with the systemic inflammatory response syndrome and sepsis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Critical Illness; Female; Hospital Mortality | 2012 |
Systemic inflammatory response syndrome caused by chronic salicylate intoxication.
Topics: Acid-Base Imbalance; Adult; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin | 1996 |