aspirin has been researched along with Stevens-Johnson Syndrome in 22 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Stevens-Johnson Syndrome: Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This review will discuss allergic and immunologic reactions to immunomodulators, penicillins and cephalosporins, sulfonamides, aspirin, and nonselective nonsteroidal anti-inflammatory drugs and consider the serious drug-related conditions of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN)." | 4.83 | 8. Drug allergy. ( Greenberger, PA, 2006) |
| "Observations of Lyell's syndrome in two girls, one 2 and the other 7 years of age, investigated serologically, histologically and by immunofluorescent technique, are reported." | 1.26 | Lyell's syndrome: histological, immunohistochemical and serological observations. ( Babala, J; Blazovsky, J; Brozman, M, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (77.27) | 18.7374 |
| 1990's | 2 (9.09) | 18.2507 |
| 2000's | 3 (13.64) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jao, T | 1 |
| Tsai, TH | 1 |
| Jeng, JS | 1 |
| NEGRO, RC | 1 |
| GENTILE RAMOS, I | 1 |
| VIGNALE, R | 1 |
| BRUM BUTLER, JL | 1 |
| Greenberger, PA | 1 |
| Lowney, ED | 1 |
| Baublis, JV | 1 |
| Kreye, GM | 1 |
| Harrell, ER | 1 |
| McKenzie, AR | 1 |
| Bianchine, JR | 1 |
| Alexander, MS | 1 |
| Andresen, BD | 1 |
| Ng, KJ | 1 |
| Dämmrich, J | 1 |
| Ormanns, W | 1 |
| Nagy, G | 1 |
| Meszáros, A | 1 |
| Mahé, A | 1 |
| Kéita, S | 1 |
| Blanc, L | 1 |
| Bobin, P | 1 |
| Kaufman, DW | 1 |
| Kelly, JP | 1 |
| Odinokova, VA | 1 |
| Kriuchkova, GS | 1 |
| Hunziker, N | 1 |
| Babala, J | 1 |
| Brozman, M | 1 |
| Blazovsky, J | 1 |
| Sfar, Z | 1 |
| Belkahia, C | 1 |
| Kamoun, M | 1 |
| Bigby, M | 1 |
| Stern, R | 1 |
| Dahle, MG | 1 |
| Spahr, A | 1 |
| Rossier, J | 1 |
| Délèze, G | 1 |
| Monnat, A | 1 |
| Bruinsma, W | 1 |
| Nava Negrete, A | 1 |
| Baker, H | 1 |
| Ocheret'ko, MP | 1 |
2 reviews available for aspirin and Stevens-Johnson Syndrome
| Article | Year |
|---|---|
8. Drug allergy.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Aspirin; Cephalosporins; Cytokines; | 2006 |
Cutaneous reactions to nonsteroidal anti-inflammatory drugs. A review.
Topics: Acetates; Anti-Inflammatory Agents; Aspirin; Drug Eruptions; Humans; Ibuprofen; Indomethacin; ortho- | 1985 |
20 other studies available for aspirin and Stevens-Johnson Syndrome
| Article | Year |
|---|---|
Aggrenox (Asasantin retard)-induced Stevens-Johnson syndrome.
Topics: Aged; Aspirin; Aspirin, Dipyridamole Drug Combination; Dipyridamole; Drug Combinations; Female; Huma | 2009 |
[Toxic epidermal necrolysis (Lyell's syndrome)].
Topics: Aspirin; Azo Compounds; Drug Eruptions; Herpesviridae Infections; Humans; Penicillins; Stevens-Johns | 1963 |
The scalded skin syndrome in small children.
Topics: Aspirin; Child, Preschool; Erythema Multiforme; Female; Humans; Infant; Infant, Newborn; Male; Penic | 1967 |
The aspirin/Reye's syndrome link.
Topics: Aspirin; Humans; Reye Syndrome; Stevens-Johnson Syndrome; Sulfonamides | 1982 |
[Lyell's syndrome and necrotizing granulomatous arteritis as simultaneous drug-induced reactions. A case report].
Topics: Adult; Aspirin; Barbiturates; Caffeine; Drug Combinations; Humans; Male; Phenacetin; Polyarteritis N | 1982 |
[Acetylsalicylic acid intolerance in Lyell syndrome].
Topics: Aspirin; Drug Combinations; Drug Eruptions; Female; Humans; Middle Aged; Respiratory Tract Infection | 1984 |
Esophageal necrosis in the Stevens-Johnson syndrome.
Topics: Adult; Aspirin; Epithelium; Esophagus; Humans; Male; Mucous Membrane; Necrosis; Stevens-Johnson Synd | 1993 |
Cutaneous reactions to analgesic-antipyretics and nonsteroidal anti-inflammatory drugs. Analysis of reports to the spontaneous reporting system of the Gruppo Italiano Studi Epidemiologici in Dermatologia.
Topics: Adverse Drug Reaction Reporting Systems; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspiri | 1993 |
Acetylsalicylic acid and other salicylates in relation to Stevens-Johnson syndrome and toxic epidermal necrolysis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Humans; Multivariate Analysi | 2001 |
[Drug-induced bullous dermatitis - Lyell's syndrome].
Topics: Adolescent; Adult; Aspirin; Drug Eruptions; Female; Humans; Male; Penicillins; Pulmonary Alveoli; Sk | 1979 |
[Toxic epidermal necrolysis (Lyell's syndrome) (author's transl)].
Topics: Aged; Aspirin; Female; Fever; Humans; Stevens-Johnson Syndrome; Terminology as Topic | 1979 |
Lyell's syndrome: histological, immunohistochemical and serological observations.
Topics: Anti-Bacterial Agents; Antibodies; Antibody Formation; Aspirin; Child; Child, Preschool; Female; Hum | 1976 |
[Severe bullous forms of drug eruptions].
Topics: Adrenal Cortex Hormones; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carbocy | 1989 |
[Toxic epidermal necrolysis. Clinical aspects and treatment illustrated by a case history].
Topics: Adult; Aspirin; Humans; Male; Stevens-Johnson Syndrome | 1988 |
[Two cases of Lyell's syndrome (toxic epidermal necrosis) in children].
Topics: Aspirin; Child; Drug Hypersensitivity; gamma-Globulins; Humans; Male; Penicillins; Prednisone; Steve | 1972 |
[Comparative study of Lyell's and Stevens-Johnson syndromes: etiologic role of drugs].
Topics: Adolescent; Adult; Aged; Aspirin; Caffeine; Child; Child, Preschool; Codeine; Female; Humans; Hydant | 1972 |
Adverse reaction profiles of drug eruptions.
Topics: Ampicillin; Analgesics; Aspirin; Chlorpromazine; Drug-Related Side Effects and Adverse Reactions; Er | 1972 |
[Stevens-Johnson syndrome. Review of 10 cases].
Topics: Adolescent; Adult; Aged; Aspirin; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; | 1971 |
Intermittent high dose oral methotrexate therapy in psoriasis.
Topics: Adult; Aged; Aspirin; Ataxia; Colitis; Female; Hematologic Diseases; Humans; Male; Methotrexate; Mid | 1970 |
[Case of toxic epidermal necrolysis in a 6-year-old child].
Topics: Aspirin; Child; Humans; Male; Stevens-Johnson Syndrome; Sulfamethazine; Tetracycline | 1970 |