Page last updated: 2024-10-23

aspirin and Staphylococcal Infections

aspirin has been researched along with Staphylococcal Infections in 35 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Staphylococcal Infections: Infections with bacteria of the genus STAPHYLOCOCCUS.

Research Excerpts

ExcerptRelevanceReference
" There was a lower rate of catheter-associated S aureus bacteremia in patients treated with aspirin versus those not treated with aspirin (0."7.74Aspirin treatment is associated with a significantly decreased risk of Staphylococcus aureus bacteremia in hemodialysis patients with tunneled catheters. ( Bayer, AS; Cheung, AL; Gemery, JM; Remillard, BD; Sedlacek, M, 2007)
" There was a lower rate of catheter-associated S aureus bacteremia in patients treated with aspirin versus those not treated with aspirin (0."3.74Aspirin treatment is associated with a significantly decreased risk of Staphylococcus aureus bacteremia in hemodialysis patients with tunneled catheters. ( Bayer, AS; Cheung, AL; Gemery, JM; Remillard, BD; Sedlacek, M, 2007)
"Rhinosinusitis is among the most common infectious complications of humoral immunodeficiency, which is not uncommon in patients with refractory CRS."2.46Rhinosinusitis and comorbidities. ( Brooks, EG; Ryan, MW, 2010)
"Aspirin did not increase bleeding in SA positive patients."1.72Staphylococcus aureus increases platelet reactivity in patients with infective endocarditis. ( Akhyari, P; Barth, M; Dannenberg, L; Helten, C; Hoffmann, T; Hohlfeld, T; Huhn, R; Kelm, M; Levkau, B; Lichtenberg, A; M'Pembele, R; Mourikis, P; Naguib, D; Petzold, T; Polzin, A; Sixt, S; Zako, S; Zeus, T, 2022)
"Severe influenza virus (IV) infections still represent a major challenge to public health."1.56The influenza replication blocking inhibitor LASAG does not sensitize human epithelial cells for bacterial infections. ( Deinhardt-Emmer, S; Ehrhardt, C; Gieselmann, L; Haupt, KF; Hrincius, ER; Ludwig, S; Niemann, S; Preugschas, HF; van Krüchten, A; Wilden, JJ, 2020)
"Aspirin was injected intraperitoneally twice daily for 11 days."1.51Aspirin alleviates orthopedic implant‑associated infection. ( Jiang, Y; Lin, JC; Qin, HJ; Ren, ML; Wang, SN; Wu, HT; Yu, B, 2019)
"Aspirin sensitivity was associated with increased concentrations of eosinophil-related mediators, as well as IgE antibodies to SAEs in nasal polyp tissue."1.32Aspirin sensitivity and IgE antibodies to Staphylococcus aureus enterotoxins in nasal polyposis: studies on the relationship. ( Bachert, C; Gevaert, P; Holtappels, G; Johannson, S; Kowalski, ML; Kuna, P; Pérez-Novo, CA; Ptasinska, A; van Cauwenberge, P, 2004)
" We sought to determine (i) whether ASA dosage influences the development of vegetations and (ii) whether ASA given with antimicrobial therapy improves the treatment outcome of infective endocarditis."1.29Influence of aspirin on development and treatment of experimental Staphylococcus aureus endocarditis. ( Marangos, MN; Nicolau, DP; Nightingale, CH; Quintiliani, R, 1995)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199011 (31.43)18.7374
1990's3 (8.57)18.2507
2000's9 (25.71)29.6817
2010's8 (22.86)24.3611
2020's4 (11.43)2.80

Authors

AuthorsStudies
Polzin, A1
Dannenberg, L1
M'Pembele, R1
Mourikis, P1
Naguib, D1
Zako, S1
Helten, C1
Petzold, T1
Levkau, B1
Hohlfeld, T1
Barth, M1
Zeus, T1
Sixt, S1
Huhn, R1
Akhyari, P1
Lichtenberg, A1
Kelm, M1
Hoffmann, T1
Jiang, Y1
Wang, SN1
Wu, HT1
Qin, HJ1
Ren, ML1
Lin, JC1
Yu, B1
Carestia, A1
Davis, RP1
Grosjean, H1
Lau, MW1
Jenne, CN1
Wilden, JJ1
van Krüchten, A1
Gieselmann, L1
Hrincius, ER1
Deinhardt-Emmer, S1
Haupt, KF1
Preugschas, HF1
Niemann, S1
Ludwig, S1
Ehrhardt, C1
Okada, Y1
Kimura, F1
Chabert, A1
Damien, P1
Verhoeven, PO1
Grattard, F1
Berthelot, P1
Zeni, F1
Panicot-Dubois, L1
Robert, S1
Dignat-George, F1
Eyraud, MA1
Pozzetto, B1
Payrastre, B1
Cognasse, F1
Garraud, O1
Hamzeh-Cognasse, H1
Longhurst, WD1
Sheele, JM1
Osthoff, M1
Sidler, JA1
Lakatos, B1
Frei, R1
Dangel, M1
Weisser, M1
Battegay, M1
Widmer, AF1
Das, UN1
Eisen, DP2
Corey, GR1
McBryde, ES1
Fowler, VG1
Miro, JM1
Cabell, CH1
Street, AC1
Paiva, MG1
Ionac, A1
Tan, RS1
Tribouilloy, C1
Pachirat, O1
Jones, SB1
Chipigina, N1
Naber, C1
Pan, A1
Ravasio, V1
Gattringer, R1
Chu, VH1
Bayer, AS3
Ryan, MW1
Brooks, EG1
Mekni, MA1
Achour, W1
Ben Hassen, A1
Meimoun, P1
Mainardi, JL1
Berrebi, A1
Marino, JP1
Waldmann, T1
Carpentier, A1
HEDWALL, P1
HEEG, E1
ABU-NASSAR, HJ1
YOW, EM1
ALEXANDER, JK1
LEWIS, JM1
HARRISON, KJ1
DUPONT, V1
MARGAIRAZ, A1
GOGUEL, A1
Pérez-Novo, CA1
Kowalski, ML1
Kuna, P1
Ptasinska, A1
Holtappels, G2
van Cauwenberge, P2
Gevaert, P2
Johannson, S1
Bachert, C2
Van Zele, T1
Watelet, JB1
Claeys, G1
Claeys, C1
Karabay, O2
Arinc, H1
Gunduz, H1
Tamer, A1
Ozhan, H1
Uyan, C1
Sedlacek, M1
Gemery, JM1
Cheung, AL1
Remillard, BD1
Demirag, MK1
Esen, S1
Zivalioglu, M1
Leblebicioglu, H1
Keceligil, HT1
Yildirim, M1
Ozdemir, D1
Lowney, ED1
Baublis, JV1
Kreye, GM1
Harrell, ER1
McKenzie, AR1
Nicolau, DP2
Marangos, MN1
Nightingale, CH2
Quintiliani, R1
Tessier, PR1
Kupferwasser, LI1
Yeaman, MR1
Shapiro, SM1
Nast, CC1
Sullam, PM1
Filler, SG1
Chan, L1
Chinnock, B1
Schlossberg, D1
Kandra, J1
Kreiser, J1
Schreiner, GE1
Saraiva, LR1
Menge, P1
Rodrigues, R1
de França, NA1
Barros, GS1
Brindeiro Filho, D1
Sevitt, S1
Stone, P1
Jackson, D1
Baar, S1
Pollock, A1
Miller, GC1
Witham, AC1
Van Reken, D1
Strauss, A1
Hernandez, A1
Feigin, RD1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Multicenter Randomized, Double-blind, Placebo-controlled, Clinical Trial of Acetylsalicylic Acid in the Prevention of Severe SARS-CoV2 Pneumonia in Hospitalised Patients (Asperum)[NCT04808895]Phase 3204 participants (Anticipated)Interventional2021-04-01Not yet recruiting
Role of Doxycycline in the Management of Patients With Chronic Rhinosinusitis With Nasal Polyps[NCT05157412]Phase 360 participants (Anticipated)Interventional2022-03-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for aspirin and Staphylococcal Infections

ArticleYear
Rhinosinusitis and comorbidities.
    Current allergy and asthma reports, 2010, Volume: 10, Issue:3

    Topics: Anti-Bacterial Agents; Aspirin; Cystic Fibrosis; Humans; Hypersensitivity; Immunity, Humoral; Immuno

2010
Manifold beneficial effects of acetyl salicylic acid and nonsteroidal anti-inflammatory drugs on sepsis.
    Intensive care medicine, 2012, Volume: 38, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Disease Models, Animal; Dose-Response Rel

2012

Other Studies

33 other studies available for aspirin and Staphylococcal Infections

ArticleYear
Staphylococcus aureus increases platelet reactivity in patients with infective endocarditis.
    Scientific reports, 2022, 07-28, Volume: 12, Issue:1

    Topics: Aspirin; Coagulase; Cohort Studies; Endocarditis, Bacterial; Humans; Pilot Projects; Platelet Aggreg

2022
Aspirin alleviates orthopedic implant‑associated infection.
    International journal of molecular medicine, 2019, Volume: 44, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Disease Models, Animal; Female; Humans; I

2019
Acetylsalicylic acid inhibits intravascular coagulation during Staphylococcus aureus-induced sepsis in mice.
    Blood, 2020, 04-09, Volume: 135, Issue:15

    Topics: Animals; Aspirin; Blood Coagulation; Disseminated Intravascular Coagulation; Mice; Mice, Inbred C57B

2020
The influenza replication blocking inhibitor LASAG does not sensitize human epithelial cells for bacterial infections.
    PloS one, 2020, Volume: 15, Issue:5

    Topics: A549 Cells; Antiviral Agents; Aspirin; Bacterial Infections; Drug Combinations; Epithelial Cells; Ge

2020
Multiple aortic thrombi in essential thrombocythaemia.
    British journal of haematology, 2021, Volume: 193, Issue:5

    Topics: Aged; Aorta, Abdominal; Aspirin; Cefazolin; Echocardiography; Heparin; Humans; Hydroxyurea; Male; St

2021
Acetylsalicylic acid differentially limits the activation and expression of cell death markers in human platelets exposed to Staphylococcus aureus strains.
    Scientific reports, 2017, 07-17, Volume: 7, Issue:1

    Topics: Aspirin; Bacterial Adhesion; Biomarkers; Blood Platelets; Cell Death; Humans; Platelet Activation; P

2017
Spontaneous methicillin-resistant Staphylococcus aureus (MRSA) meningitis.
    The American journal of emergency medicine, 2018, Volume: 36, Issue:5

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Aspirin; Cerebellum; Female; Humans; Meningitis, Ba

2018
Low-Dose Acetylsalicylic Acid Treatment and Impact on Short-Term Mortality in Staphylococcus aureus Bloodstream Infection: A Propensity Score-Matched Cohort Study.
    Critical care medicine, 2016, Volume: 44, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bacteremia; Cross Infection; Escherichia co

2016
Low-Dose Acetylsalicylic Acid and Short-Term Mortality in Staphylococcus aureus Bloodstream Infection.
    Critical care medicine, 2016, Volume: 44, Issue:8

    Topics: Aspirin; Bacteremia; Cross Infection; Humans; Methicillin-Resistant Staphylococcus aureus; Staphyloc

2016
Reduced valve replacement surgery and complication rate in Staphylococcus aureus endocarditis patients receiving acetyl-salicylic acid.
    The Journal of infection, 2009, Volume: 58, Issue:5

    Topics: Aged; Aspirin; Cohort Studies; Embolism; Endocarditis, Bacterial; Female; Heart Failure; Heart Valve

2009
Comment on the effect of aspirin on adherence of slime-producing, coagulase-negative Staphylococci to vascular grafts.
    Annals of vascular surgery, 2012, Volume: 26, Issue:3

    Topics: Aspirin; Bacterial Adhesion; Blood Vessel Prosthesis; Humans; Prosthesis-Related Infections; Staphyl

2012
[Staphylococcus epidermidis infective endocarditis after mitral surgery, successfully treated with aspirin and antibiotics: a case report].
    Annales de cardiologie et d'angeiologie, 2000, Volume: 49, Issue:6

    Topics: Adult; Anti-Bacterial Agents; Aspirin; Endocarditis, Bacterial; Female; Humans; Mitral Valve; Platel

2000
[Modification of staphylococcal infections of the rat kidney by analgesics].
    Arzneimittel-Forschung, 1961, Volume: 11

    Topics: Analgesics; Animals; Aspirin; Kidney Diseases; Phenacetin; Rats; Staphylococcal Infections

1961
PRIMARY STAPHYLOCOCCAL PERICARDITIS COMPLICATING CARDIOTOMY: A REPORT OF A CASE WITH A NOTE ON INTRAPERICARDIAL METHICILLIN THERAPY.
    Annals of internal medicine, 1964, Volume: 60

    Topics: Aspirin; Bacterial Infections; Cardiac Surgical Procedures; Methicillin; Penicillins; Pericarditis;

1964
BOILS; THEIR TREATMENT AND PREVENTION.
    Nursing times, 1964, May-08, Volume: 60

    Topics: Analgesics; Analgesics, Non-Narcotic; Animals; Anti-Bacterial Agents; Antipyretics; Aspirin; Bandage

1964
[SOME EXAMPLES OF "PSEUDO-INFECTIOUS" PICTURES INDUCED BY DRUGS].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1964, Dec-14, Volume: 40

    Topics: Adolescent; Anticonvulsants; Arsenicals; Aspirin; Barbiturates; Diagnosis, Differential; Drug Erupti

1964
Aspirin sensitivity and IgE antibodies to Staphylococcus aureus enterotoxins in nasal polyposis: studies on the relationship.
    International archives of allergy and immunology, 2004, Volume: 133, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Proteins; Bronchial Provocation Tests

2004
Staphylococcus aureus colonization and IgE antibody formation to enterotoxins is increased in nasal polyposis.
    The Journal of allergy and clinical immunology, 2004, Volume: 114, Issue:4

    Topics: Adult; Aspirin; Asthma; Chronic Disease; Drug Hypersensitivity; Enterotoxins; Female; Humans; Immuno

2004
A new effect of acetylsalicylic acid? Significantly lower prevalence of nasal carriage of Staphylococcus aureus among patients receiving orally administered acetylsalicylic acid.
    Infection control and hospital epidemiology, 2006, Volume: 27, Issue:3

    Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carrier State; Female; Human

2006
Aspirin treatment is associated with a significantly decreased risk of Staphylococcus aureus bacteremia in hemodialysis patients with tunneled catheters.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2007, Volume: 49, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Aspirin; Bacteremia; Catheters, Indwelling; F

2007
The effect of aspirin on adherence of slime-producing, coagulase-negative staphylococci to vascular grafts.
    Annals of vascular surgery, 2007, Volume: 21, Issue:4

    Topics: Aspirin; Bacterial Adhesion; Blood Vessel Prosthesis; Coagulase; Colony Count, Microbial; Humans; Po

2007
Decreasing risk of Staphylococcus aureus infections.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2007, Volume: 50, Issue:2

    Topics: Aspirin; Humans; Risk Factors; Staphylococcal Infections; Staphylococcus aureus

2007
The scalded skin syndrome in small children.
    Archives of dermatology, 1967, Volume: 95, Issue:4

    Topics: Aspirin; Child, Preschool; Erythema Multiforme; Female; Humans; Infant; Infant, Newborn; Male; Penic

1967
Influence of aspirin on development and treatment of experimental Staphylococcus aureus endocarditis.
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Aorta; Aspirin; Dose-Response Relationship, Drug; Endocarditis, Bact

1995
Beneficial effect of combination antiplatelet therapy on the development of experimental Staphylococcus aureus endocarditis.
    International journal of antimicrobial agents, 1999, Volume: 11, Issue:2

    Topics: Animals; Aspirin; Drug Therapy, Combination; Endocarditis, Bacterial; Female; Platelet Aggregation I

1999
Acetylsalicylic acid reduces vegetation bacterial density, hematogenous bacterial dissemination, and frequency of embolic events in experimental Staphylococcus aureus endocarditis through antiplatelet and antibacterial effects.
    Circulation, 1999, Jun-01, Volume: 99, Issue:21

    Topics: Animals; Anti-Bacterial Agents; Aspirin; Colony Count, Microbial; Embolism; Endocarditis, Bacterial;

1999
Clinicopathological conference: multisystem failure in a child.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2000, Volume: 7, Issue:2

    Topics: Anti-Bacterial Agents; Aspirin; Child; Clindamycin; Female; Humans; Immunoglobulins, Intravenous; Mu

2000
Possible Kawasaki disease in a 20-year-old woman.
    Archives of dermatology, 1979, Volume: 115, Issue:12

    Topics: Adult; Age Factors; Aspirin; Diagnosis, Differential; Erythromycin; Female; Humans; Lymphatic Diseas

1979
Drug-related nephropathy.
    Contributions to nephrology, 1978, Volume: 10

    Topics: Analgesics; Aspirin; Heroin Dependence; Humans; Inulin; Kidney; Kidney Cortex Necrosis; Kidney Disea

1978
[Evolutive aspect of the echocardiographic image of the vegetation in tricuspid valve endocarditis cured with clinical treatment. A case report].
    Arquivos brasileiros de cardiologia, 1988, Volume: 51, Issue:5

    Topics: Aspirin; Cefotaxime; Child; Echocardiography; Endocarditis, Bacterial; Gentamicins; Humans; Male; St

1988
Acute Heinz-body anaemia in burned patients.
    Lancet (London, England), 1973, Sep-01, Volume: 2, Issue:7827

    Topics: Adult; Ampicillin; Anemia, Hemolytic; Aspirin; Burns; Carbenicillin; Cloxacillin; Digoxin; Erythrocy

1973
Delayed febrile pleuropericarditis after sepsis. A possible analogue of the postcardiotomy syndrome.
    Annals of internal medicine, 1973, Volume: 79, Issue:2

    Topics: Adult; Aspirin; Blood Sedimentation; Cardiomegaly; Erythrocytes; Female; Fever; Heart Auscultation;

1973
Infectious pericarditis in children.
    The Journal of pediatrics, 1974, Volume: 85, Issue:2

    Topics: Adenoviridae Infections; Adolescent; Ampicillin; Aortic Aneurysm; Aspirin; Bacterial Infections; Chi

1974