Page last updated: 2024-10-23

aspirin and Sickle Cell Trait

aspirin has been researched along with Sickle Cell Trait in 4 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Sickle Cell Trait: The condition of being heterozygous for hemoglobin S.

Research Excerpts

ExcerptRelevanceReference
" In this study, we describe, to the best of our knowledge, the first report of LV only associated with sickle cell trait with significant improvement on aspirin."7.78Livedoid vasculopathy associated with sickle cell trait: significant improvement on aspirin treatment. ( Abbas, O; El Khoury, J; Kibbi, AG; Kurban, M; Taher, A, 2012)
"The effects of low doses of aspirin on the frequency and severity of painful vaso-occlusive crises were evaluated in children with sickle hemoglobinopathies."5.05Trial of low doses of aspirin as prophylaxis in sickle cell disease. ( Greenberg, J; Halus, J; Ohene-Frempong, K; Schwartz, E; Way, C, 1983)
" In this study, we describe, to the best of our knowledge, the first report of LV only associated with sickle cell trait with significant improvement on aspirin."3.78Livedoid vasculopathy associated with sickle cell trait: significant improvement on aspirin treatment. ( Abbas, O; El Khoury, J; Kibbi, AG; Kurban, M; Taher, A, 2012)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lang, PA1
Kasinathan, RS1
Brand, VB1
Duranton, C1
Lang, C1
Koka, S1
Shumilina, E1
Kempe, DS1
Tanneur, V1
Akel, A1
Lang, KS1
Foller, M1
Kun, JF1
Kremsner, PG1
Wesselborg, S1
Laufer, S1
Clemen, CS1
Herr, C1
Noegel, AA1
Wieder, T1
Gulbins, E1
Lang, F1
Huber, SM1
El Khoury, J1
Taher, A1
Kurban, M1
Kibbi, AG1
Abbas, O1
Greenberg, J1
Ohene-Frempong, K1
Halus, J1
Way, C1
Schwartz, E1
Worley, RJ1
Gant, NF1
Everett, RB1
MacDonald, PC1

Trials

1 trial available for aspirin and Sickle Cell Trait

ArticleYear
Trial of low doses of aspirin as prophylaxis in sickle cell disease.
    The Journal of pediatrics, 1983, Volume: 102, Issue:5

    Topics: Adolescent; Anemia, Sickle Cell; Aspirin; Blood Platelets; Child; Child, Preschool; Double-Blind Met

1983

Other Studies

3 other studies available for aspirin and Sickle Cell Trait

ArticleYear
Accelerated clearance of Plasmodium-infected erythrocytes in sickle cell trait and annexin-A7 deficiency.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2009, Volume: 24, Issue:5-6

    Topics: Animals; Annexin A7; Aspirin; Calcium; Dinoprostone; Erythrocytes; Genotype; Hemoglobin A; Hemoglobi

2009
Livedoid vasculopathy associated with sickle cell trait: significant improvement on aspirin treatment.
    International wound journal, 2012, Volume: 9, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biopsy; Follow-Up Studies; Humans; Livedo R

2012
Vascular responsiveness to pressor agents during human pregnancy.
    The Journal of reproductive medicine, 1979, Volume: 23, Issue:3

    Topics: Aldosterone; Angiotensin II; Aspirin; Female; Hematocrit; Humans; Hypertension; Indomethacin; Pregna

1979