aspirin has been researched along with Shock, Traumatic in 10 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Shock, Traumatic: Shock produced as a result of trauma.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diaspirin cross-linked hemoglobin (DCLHb) has demonstrated a pressor effect that could adversely affect traumatic hemorrhagic shock patients through diminished perfusion to vital organs, causing base deficit (BD) and lactate abnormalities." | 7.76 | Diaspirin cross-linked hemoglobin infusion did not influence base deficit and lactic acid levels in two clinical trials of traumatic hemorrhagic shock patient resuscitation. ( Gao, W; Koenigsberg, MD; Philbin, NB; Sloan, EP, 2010) |
| "The efficacy trial of diaspirin cross-linked hemoglobin (DCLHb) in traumatic hemorrhagic shock demonstrated an unexpected mortality imbalance, prompting a three-step review to better understand the cause of this finding." | 7.71 | Post hoc mortality analysis of the efficacy trial of diaspirin cross-linked hemoglobin in the treatment of severe traumatic hemorrhagic shock. ( Brunett, PH; Bynoe, RP; Dalsey, WC; Koenigsberg, M; Morris, JA; Ochsner, MG; Sloan, EP; Tinkoff, G, 2002) |
| "Diaspirin cross-linked hemoglobin (DCLHb) has demonstrated a pressor effect that could adversely affect traumatic hemorrhagic shock patients through diminished perfusion to vital organs, causing base deficit (BD) and lactate abnormalities." | 3.76 | Diaspirin cross-linked hemoglobin infusion did not influence base deficit and lactic acid levels in two clinical trials of traumatic hemorrhagic shock patient resuscitation. ( Gao, W; Koenigsberg, MD; Philbin, NB; Sloan, EP, 2010) |
| "The efficacy trial of diaspirin cross-linked hemoglobin (DCLHb) in traumatic hemorrhagic shock demonstrated an unexpected mortality imbalance, prompting a three-step review to better understand the cause of this finding." | 3.71 | Post hoc mortality analysis of the efficacy trial of diaspirin cross-linked hemoglobin in the treatment of severe traumatic hemorrhagic shock. ( Brunett, PH; Bynoe, RP; Dalsey, WC; Koenigsberg, M; Morris, JA; Ochsner, MG; Sloan, EP; Tinkoff, G, 2002) |
| "In anesthetized dogs soft tissue trauma resulting in hypovolemia was associated with pulmonary trapping of 51Cr tagged platelets." | 1.25 | Development and treatment of post-traumatic pulmonary platelet trapping. ( Peer, RM; Schwartz, SI, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (40.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sloan, EP | 5 |
| Philbin, NB | 2 |
| Koenigsberg, MD | 2 |
| Gao, W | 2 |
| Koenigsberg, M | 2 |
| Clark, JM | 1 |
| Desai, A | 1 |
| Ward, CG | 1 |
| Shackford, SR | 1 |
| Brunett, PH | 1 |
| Bynoe, RP | 1 |
| Morris, JA | 1 |
| Tinkoff, G | 1 |
| Dalsey, WC | 1 |
| Ochsner, MG | 1 |
| Peer, RM | 1 |
| Schwartz, SI | 1 |
| Hunt, TK | 1 |
| Loew, D | 1 |
| Hey, D | 1 |
| Langer, P | 1 |
| Boehme, K | 1 |
| Bergentz, SE | 1 |
| Lewis, D | 1 |
| Ljungqvist, U | 1 |
10 other studies available for aspirin and Shock, Traumatic
| Article | Year |
|---|---|
The lack of consistent diaspirin cross-linked hemoglobin infusion blood pressure effects in the US and EU traumatic hemorrhagic shock clinical trials.
Topics: Adult; Aspirin; Blood Pressure; Clinical Trials as Topic; Female; Hemoglobins; Humans; Male; Middle | 2010 |
Diaspirin cross-linked hemoglobin infusion did not influence base deficit and lactic acid levels in two clinical trials of traumatic hemorrhagic shock patient resuscitation.
Topics: Acidosis, Lactic; Adult; Aspirin; Emergency Medical Services; Emergency Treatment; Europe; Fluid The | 2010 |
The use of the Revised Trauma Score as an entry criterion in traumatic hemorrhagic shock studies: data from the DCLHb clinical trials.
Topics: Adult; Aspirin; Clinical Trials, Phase III as Topic; Female; Glasgow Coma Scale; Hemoglobins; Humans | 2012 |
Post hoc mortality analysis on the efficacy trial of diaspirin cross-linked hemoglobin in the treatment of severe traumatic hemorrhagic shock.
Topics: Aspirin; Hemoglobins; Humans; Shock, Hemorrhagic; Shock, Traumatic; Survival Analysis | 2002 |
Effect of small-volume resuscitation on intracranial pressure and related cerebral variables.
Topics: Animals; Aspirin; Brain Injuries; Cerebrovascular Circulation; Dextrans; Disease Models, Animal; Dru | 1997 |
Post hoc mortality analysis of the efficacy trial of diaspirin cross-linked hemoglobin in the treatment of severe traumatic hemorrhagic shock.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Female; Hemoglobins; Humans; Male; Middle Aged; | 2002 |
Development and treatment of post-traumatic pulmonary platelet trapping.
Topics: Animals; Aspirin; Biopsy; Blood Cell Count; Blood Platelets; Chromium Radioisotopes; Dextrans; Disea | 1975 |
Injury and repair in acute gastroduodenal ulceration.
Topics: Acute Disease; Aspirin; Burns; Cushing Syndrome; Duodenal Ulcer; Gastric Mucosa; Humans; Infections; | 1973 |
[Quantitative and qualitative behaviour of the thrombocytes during scalding shock in the rabbit (author's transl)].
Topics: Animals; Aspirin; Blood Platelets; Burns; Disease Models, Animal; Female; Platelet Adhesiveness; Rab | 1973 |
[The lung in shock: accumulation of thrombocytes following trauma and intravasal coagulation].
Topics: Animals; Aspirin; Blood Platelets; Chromium Isotopes; Dogs; Fibrinogen; Iodine Radioisotopes; Kidney | 1971 |