aspirin and Shock, Septic studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Shock, Septic: Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.

Research Excerpts

Excerpt	Relevance	Reference
"The endotoxin shock induced in mice by injection of viable Listeria monocytogenes and challenged with endotoxin can be alleviated by combined administration of mannoheptulose with acetylsalicylate or sulindac."	7.67	Effect of combined treatment of anti-inflammatory drug and mannoheptulose on the production of tumour necrosis factor and endotoxin shock in mice. ( Cheng, CP; Choy, YM; Fung, KP; Lee, CY; Loh, SC; Luey, LU, 1988)
" We compared the effects of the classical cyclooxygenase inhibitor aspirin with that of the dual cyclooxygenase and lipoxygenase inhibitor ketoprofen on the behavior of platelets tagged with 111In-labeled oxine in multiple organs during endotoxin shock."	3.69	Effects of two different inhibitors of the arachidonic acid metabolism on platelet sequestration in endotoxic shock. ( Owunnwanne, A; Sigurdsson, GH; Youssef, HA, 1994)
"The effect of sodium 4-[alpha-hydroxy-5-(imidazolyl)-2-methylbenzyl]-3,5-dimethyl benzoate dihydrate (Y-20811), a selective thromboxane (TX) synthetase inhibitor, on endotoxin shock was investigated in comparison with aspirin."	3.68	Protective effect of Y-20811, a long-lasting thromboxane synthetase inhibitor, on endotoxin shock in rabbits. ( Mikashima, H; Muramoto, Y, 1990)
"The endotoxin shock induced in mice by injection of viable Listeria monocytogenes and challenged with endotoxin can be alleviated by combined administration of mannoheptulose with acetylsalicylate or sulindac."	3.67	Effect of combined treatment of anti-inflammatory drug and mannoheptulose on the production of tumour necrosis factor and endotoxin shock in mice. ( Cheng, CP; Choy, YM; Fung, KP; Lee, CY; Loh, SC; Luey, LU, 1988)
"Coronary aneurysms were less frequent in adults than in children."	2.43	Adult Kawasaki disease: report of two cases and literature review. ( Broussolle, C; Durand, DV; Marchand, G; Sève, P; Smail, A; Stankovic, K, 2005)
"Atherosclerosis is considered as a moderate systemic inflammation and we hypothesise that this chronic condition could have an impact on the outcome in sepsis."	1.39	Effects of low-dose acetylsalicylic acid and atherosclerotic vascular diseases on the outcome in patients with severe sepsis or septic shock. ( Boettel, J; Breuel, H; Kabisch, B; Lösche, W; Otto, GP; Sossdorf, M; Winning, J, 2013)
"During cardiac tamponade, critical oxygen delivery was 12."	1.31	Diaspirin cross-linked hemoglobin improves oxygen extraction capabilities in endotoxic shock. ( Creteur, J; De Backer, D; Sun, Q; Vincent, JL; Zhang, H, 2000)
"Features included fever, leukocytosis with increased band forms, hypotension with a reduced SVR and multiple system organ failure (ARDS, encephalopathy, renal failure, and DIC)."	1.28	Fever, hyperdynamic shock, and multiple-system organ failure. A pseudo-sepsis syndrome associated with chronic salicylate intoxication. ( Leatherman, JW; Schmitz, PG, 1991)
"Early endotoxic shock in the rat is associated with marked elevations of plasma TxB2 (the stable metabolite of TxA2) and lesser increases in plasma 6-keto-PGF1 alpha (the stable metabolite of PGI2)."	1.27	The potential role of thromboxane and prostacyclin in endotoxic and septic shock. ( Butler, RR; Cook, JA; Halushka, PV; Rambo, W; Reines, HD; Wise, WC, 1984)
"Pretreatment with aspirin (15 or 100 mg/kg) 30 minutes prior to endotoxin also significantly (p less than 0."	1.27	Studies on the beneficial effects of aspirin in endotoxic shock. Relationship to inhibition of arachidonic acid metabolism. ( Cook, JA; Halushka, PV; Wise, WC, 1983)
"Pretreatment with aspirin (15 or 100 mg/kg) 30 min before endotoxin significantly (P less than ."	1.26	Protective effects of aspirin in endotoxic shock. ( Cook, JA; Halushka, PV; Wise, WC, 1981)

Timeframe	Studies, this research(%)	All Research%
pre-1990	41 (63.08)	18.7374
1990's	11 (16.92)	18.2507
2000's	6 (9.23)	29.6817
2010's	7 (10.77)	24.3611
2020's	0 (0.00)	2.80

Trial			Phase	Enrollment	Study Type	Start Date	Status
Prasugrel in the Prevention of Severe SARS-CoV2 Pneumonia in Hospitalised Patients[NCT04445623]			Phase 3	128 participants (Anticipated)	Interventional	2020-07-31	Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
Adult Kawasaki disease: report of two cases and literature review. Seminars in arthritis and rheumatism, 2005, Volume: 34, Issue:6 Topics: Adult; Age of Onset; Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin;	2005
[Disseminated intravascular coagulation. II. Therapeutic problems]. Minerva medica, 1982, Feb-25, Volume: 73, Issue:7 Topics: Antifibrinolytic Agents; Antithrombin III Deficiency; Anuria; Aprotinin; Aspirin; Blood Transfusion;	1982
[Thrombosis prevention and treatment in pediatrics]. Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1979, Jan-01, Volume: 34, Issue:1 Topics: Adolescent; Arterial Occlusive Diseases; Aspirin; Bioprosthesis; Child; Child, Preschool; Coumarins;	1979
Septic shock and disturbances in coagulation. Triangle; the Sandoz journal of medical science, 1974, Volume: 13, Issue:3 Topics: Acidosis; Acute Kidney Injury; Aminocaproates; Aspirin; Blood Coagulation Disorders; Blood Coagulati	1974

Article	Year
Kawasaki shock syndrome presenting as toxic shock syndrome. International journal of rheumatic diseases, 2013, Volume: 16, Issue:4 Topics: Adolescent; Aspirin; Comorbidity; Coronary Aneurysm; Diagnosis, Differential; Echocardiography; Fema	2013
The effects of aspirin, flurbiprofen, and NO-donating acetylsalicylic acid (NCX 4016) on mice models of endotoxic and septic shock. Turkish journal of medical sciences, 2015, Volume: 45, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Disease Models, Animal; Flurbiprofen; Liv	2015
Septic shock from community-onset pneumonia: is there a role for aspirin plus macrolides combination? Intensive care medicine, 2016, Volume: 42, Issue:2 Topics: Anti-Bacterial Agents; Aspirin; Community-Acquired Infections; Drug Combinations; Humans; Macrolides	2016
Role of aspirin in patients with septic shock: a complex and intriguing relationship. Intensive care medicine, 2016, Volume: 42, Issue:6 Topics: Aspirin; Humans; Shock, Septic	2016
Spontaneous pulmonary hematoma in a patient with sepsis treated with dual antiplatelet therapy. Wiener klinische Wochenschrift, 2016, Volume: 128, Issue:Suppl 7 Topics: Aged; Anticoagulants; Aspirin; Diagnosis, Differential; Hematoma; Humans; Lung Diseases; Male; Plate	2016
Prasugrel inhibits platelet-leukocyte interaction and reduces inflammatory markers in a model of endotoxic shock in the mouse. Thrombosis and haemostasis, 2012, Volume: 107, Issue:6 Topics: Animals; Anti-Inflammatory Agents; Aspirin; Biomarkers; Blood Platelets; Disease Models, Animal; Dow	2012
Effects of low-dose acetylsalicylic acid and atherosclerotic vascular diseases on the outcome in patients with severe sepsis or septic shock. Platelets, 2013, Volume: 24, Issue:6 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Atherosclerosis; Blood Coagulation; Clopidog	2013
[SHOCK-LIKE SYMPTOMS CAUSED BY DRUGS AND THEIR TREATMENT. (1) BASIC PRINCIPLES]. Jibi inkoka Otolaryngology, 1963, Volume: 35 Topics: Adrenocorticotropic Hormone; Aminosalicylic Acid; Aminosalicylic Acids; Anaphylaxis; Anti-Bacterial	1963
[SHOCK-LIKE SYMPTOMS CAUSED BY DRUGS AND THEIR TREATMENT. (2) CLINICAL ASPECTS]. Jibi inkoka Otolaryngology, 1963, Volume: 35 Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Aspirin; Blood Chemical Analysis; Body Constitut	1963
Critical roles of platelets in lipopolysaccharide-induced lethality: effects of glycyrrhizin and possible strategy for acute respiratory distress syndrome. International immunopharmacology, 2005, Volume: 5, Issue:3 Topics: Animals; Antibodies, Monoclonal; Aspirin; Blood Platelets; Dexamethasone; Glycyrrhizic Acid; Lipopol	2005
The potential role of thromboxane and prostacyclin in endotoxic and septic shock. The American journal of emergency medicine, 1984, Volume: 2, Issue:1 Topics: Animals; Arachidonic Acids; Aspirin; Cyclooxygenase Inhibitors; Epoprostenol; Fatty Acids; Gentamici	1984
Studies on the beneficial effects of aspirin in endotoxic shock. Relationship to inhibition of arachidonic acid metabolism. The American journal of medicine, 1983, Jun-14, Volume: 74, Issue:6A Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acids; Aspirin; Blood Platelets; Fibrin Fibrinoge	1983
Septic shock in obstetrics. Clinical obstetrics and gynecology, 1984, Volume: 27, Issue:1 Topics: Animals; Anti-Bacterial Agents; Aspirin; Disseminated Intravascular Coagulation; Dopamine; Emergenci	1984
Case-control research. Temporal precedence and other problems of the exposure-disease relationship. Archives of internal medicine, 1984, Volume: 144, Issue:6 Topics: Adult; Aspirin; Child; Epidemiologic Methods; Female; Humans; Research Design; Reye Syndrome; Risk;	1984
Protective effects of aspirin in endotoxic shock. The Journal of pharmacology and experimental therapeutics, 1981, Volume: 218, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Glucose; Fibrin Fibrinogen Degradation Product	1981
Prostaglandins in shock: to give or to block? Advances in shock research, 1980, Volume: 3 Topics: Animals; Arachidonic Acids; Aspirin; Dogs; Epoprostenol; Hemodynamics; Indomethacin; Papio; Prostagl	1980
Effects of acetylsalicylic acid and prostaglandin on endotoxin-induced pulmonary platelet sequestration. Acta chirurgica Scandinavica, 1981, Volume: 147, Issue:3 Topics: Alprostadil; Animals; Aspirin; Blood Platelets; Dogs; Drug Therapy, Combination; Endotoxins; Female;	1981
Endotoxic shock in the primate: effects of aspirin and dipyridamole administration. American journal of obstetrics and gynecology, 1981, Aug-15, Volume: 140, Issue:8 Topics: Animals; Aspirin; Blood Coagulation; Blood Pressure; Depression, Chemical; Dipyridamole; Disease Mod	1981
Calcitonin gene-related peptide release in endotoxicosis may be mediated by prostaglandins. Shock (Augusta, Ga.), 1995, Volume: 3, Issue:1 Topics: Animals; Aspirin; Blood Glucose; Blood Pressure; Calcitonin Gene-Related Peptide; Cyclooxygenase Inh	1995
Effects of two different inhibitors of the arachidonic acid metabolism on platelet sequestration in endotoxic shock. Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1994, Volume: 194, Issue:5 Topics: Animals; Arachidonic Acids; Aspirin; Blood Platelets; Endotoxins; Hemodynamics; Indium Radioisotopes	1994
Toxic shock syndrome toxin-secreting Staphylococcus aureus in Kawasaki syndrome. Lancet (London, England), 1994, Jan-29, Volume: 343, Issue:8892 Topics: Aspirin; Child; Combined Modality Therapy; Humans; Immunoglobulins, Intravenous; Male; Mucocutaneous	1994
Effects of ketoprofen on respiratory and circulatory changes in endotoxic shock. Intensive care medicine, 1993, Volume: 19, Issue:6 Topics: Animals; Aspirin; Blood Circulation; Carbon Dioxide; Disease Models, Animal; Drug Evaluation, Precli	1993
The effects of diaspirin cross-linked hemoglobin in sepsis. Shock (Augusta, Ga.), 1996, Volume: 5, Issue:2 Topics: Albumins; Animals; Aspirin; Blood Pressure; Hemodynamics; Hemoglobins; Infusions, Intravenous; Male;	1996
Nitric oxide overproduction in septic shock--methemoglobin concentrations and blockade with diaspirin cross-linked hemoglobin. Critical care medicine, 1997, Volume: 25, Issue:9 Topics: Aspirin; Hemoglobins; Humans; Methemoglobin; Nitric Oxide; Shock, Septic	1997
Clinicopathological conference: multisystem failure in a child. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2000, Volume: 7, Issue:2 Topics: Anti-Bacterial Agents; Aspirin; Child; Clindamycin; Female; Humans; Immunoglobulins, Intravenous; Mu	2000
Diaspirin cross-linked hemoglobin improves oxygen extraction capabilities in endotoxic shock. Journal of applied physiology (Bethesda, Md. : 1985), 2000, Volume: 89, Issue:4 Topics: Animals; Aspirin; Blood Pressure; Blood Substitutes; Cardiac Output; Cardiac Tamponade; Dogs; Endoto	2000
Safeguarding patients in clinical trials with high mortality rates. American journal of respiratory and critical care medicine, 2001, Jul-15, Volume: 164, Issue:2 Topics: Aspirin; Blood Substitutes; Clinical Trials as Topic; Critical Illness; Hemoglobins; Human Growth Ho	2001
The hemodynamic effects of diaspirin cross-linked hemoglobin in dopamine-resistant endotoxic shock in swine. Artificial cells, blood substitutes, and immobilization biotechnology, 2002, Volume: 30, Issue:2 Topics: Animals; Aspirin; Blood Pressure; Blood Substitutes; Cardiotonic Agents; Dopamine; Drug Resistance;	2002
[Effects of various drugs on microaggregate formation in endotoxin shock (author's transl)]. Masui. The Japanese journal of anesthesiology, 1979, Volume: 28, Issue:12 Topics: Animals; Aspirin; Bucladesine; Dogs; Methylprednisolone; Platelet Aggregation; Platelet Count; Shock	1979
Antiplatelet treatment in septic shock with severe bleeding and thrombocytopenia. Thrombosis and haemostasis, 1977, Aug-31, Volume: 38, Issue:2 Topics: Adult; Aminocaproic Acid; Aspirin; Dipyridamole; Female; Humans; Lysine; Platelet Aggregation; Purpu	1977
Experimental meningococcal septicemia. Effect of aspirin therapy. Archives of pathology & laboratory medicine, 1978, Volume: 102, Issue:10 Topics: Animals; Aspirin; Female; Fibrin; Kidney Glomerulus; Kidney Tubular Necrosis, Acute; Lung; Meningoco	1978
[Effect of acetylsalicylic acid on experimentally induced endotoxin reactions in swine]. Archiv fur experimentelle Veterinarmedizin, 1976, Volume: 30, Issue:6 Topics: Animals; Aspirin; Drug Interactions; Endotoxins; Escherichia coli; Indomethacin; Shock, Septic; Swin	1976
Prostaglandins and the hemodynamic course of endotoxin shock. The Journal of surgical research, 1976, Volume: 20, Issue:6 Topics: Animals; Aspirin; Blood Pressure; Cardiac Output; Disease Models, Animal; Haplorhini; Hemodynamics;	1976
Evaluation of antithrombotic properties of suloctidil in comparison with aspirin and dipyridamole. Thrombosis research, 1976, Volume: 9, Issue:2 Topics: Animals; Aspirin; Dipyridamole; Disease Models, Animal; Drug Evaluation, Preclinical; Fibrinolytic A	1976
Improved survival in endotoxemia with aspirin and indomethacin pretreatment. Surgical forum, 1976, Volume: 27, Issue:62 Topics: Animals; Aspirin; Dogs; Endotoxins; Hemodynamics; Indomethacin; Male; Shock, Septic	1976
Endotoxin-induced prostaglandin E and F release in dogs. The American journal of physiology, 1975, Volume: 228, Issue:2 Topics: Animals; Aorta; Aspirin; Blood Pressure; Cardiac Output; Dogs; Indomethacin; Portal Vein; Prostaglan	1975
Ibuprofen, indomethacin, and high-dose aspirin, but not low-dose aspirin or imidazole, inhibit CGRP elevations in plasma during endotoxicosis. Annals of the New York Academy of Sciences, 1992, Jun-30, Volume: 657 Topics: Animals; Aspirin; Calcitonin Gene-Related Peptide; Dose-Response Relationship, Drug; Endotoxins; Ibu	1992
[Adult respiratory distress syndrome (ARDS)]. Nihon rinsho. Japanese journal of clinical medicine, 1990, Volume: 48, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Aprotinin; Aspirin; Disseminated Intravascular Coagulation; Female;	1990
The effects of an infusion of prostacyclin on their endotoxin shock in rabbits. Folia haematologica (Leipzig, Germany : 1928), 1990, Volume: 117, Issue:1 Topics: Animals; Aspirin; Blood Coagulation; Blood Platelets; Blood Pressure; Carbon Dioxide; Epoprostenol;	1990
Fever, hyperdynamic shock, and multiple-system organ failure. A pseudo-sepsis syndrome associated with chronic salicylate intoxication. Chest, 1991, Volume: 100, Issue:5 Topics: Adult; Aged; Aspirin; Enzyme-Linked Immunosorbent Assay; Female; Fever; Hemodynamics; Humans; Hypote	1991
Protective effect of Y-20811, a long-lasting thromboxane synthetase inhibitor, on endotoxin shock in rabbits. Thrombosis research, 1990, Feb-15, Volume: 57, Issue:4 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Pressure; Imidazoles; Male; Rabbits; Shock, Se	1990
Influence of inhibitors of the eicosanoid metabolism, and of eicosanoids- and PAF-acether antagonists on mortality and some biochemical parameters of three shock models. Progress in clinical and biological research, 1989, Volume: 301 Topics: Anaphylaxis; Animals; Aspirin; Diterpenes; Fatty Acids, Unsaturated; Female; Ginkgolides; Imidazoles	1989
Acetylsalicylic acid, BM 13.177 and picotamide improve the survival of endotoxin-infused rabbits. Thrombosis research, 1988, Dec-01, Volume: 52, Issue:5 Topics: Animals; Aspirin; Endotoxins; Female; Imidazoles; Male; Methylprednisolone; Phthalic Acids; Rabbits;	1988
Beneficial effects of prostacyclin in a rabbit endotoxin shock model. Thrombosis research, 1988, Aug-15, Volume: 51, Issue:4 Topics: Animals; Aspirin; Blood Cells; Blood Platelets; Epoprostenol; Female; Lipopolysaccharides; Male; Rab	1988
Inhibition of lipoxygenase (LOX) or of cyclooxygenase (COX) improves survival of rats in endotoxin shock. Biomedica biochimica acta, 1988, Volume: 47, Issue:10-11 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Cyclooxygenase Inhibitors; Disease Models, Animal; L	1988
Effect of combined treatment of anti-inflammatory drug and mannoheptulose on the production of tumour necrosis factor and endotoxin shock in mice. Cancer letters, 1988, Volume: 39, Issue:2 Topics: Animals; Anti-Inflammatory Agents; Aspirin; Drug Therapy, Combination; Heptoses; Lipopolysaccharides	1988
Lack of effect of glucocorticoids upon plasma thromboxane in patients in a state of shock. Surgery, gynecology & obstetrics, 1985, Volume: 160, Issue:4 Topics: Aspirin; Blood Coagulation; Glucocorticoids; Humans; Methylprednisolone; Oxygen; Oxygen Consumption;	1985
[Anti-platelet actions of salicylates: in vivo, ex vivo and in vitro effects of choline salicylate]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1985, Volume: 86, Issue:1 Topics: Adenosine Diphosphate; Animals; Aspirin; Blood Platelets; Calcium; Choline; Drug Combinations; In Vi	1985
Antihemostatic and antithrombotic effects of XC386. Thrombosis research, 1985, Aug-15, Volume: 39, Issue:4 Topics: Animals; Aspirin; Blood Coagulation; Hematocrit; Heparin; Indomethacin; Mice; Platelet Aggregation;	1985
Mechanisms of change in thoracic duct lymph flow during hypotensive states. Annals of surgery, 1970, Volume: 171, Issue:6 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Aspirin; Capillary Permeability;	1970
Thrombocytopenia and bleeding complications in severe cases of meningococcal infection treated with heparin, dextran 70 and chlorpromazine. Scandinavian journal of infectious diseases, 1972, Volume: 4, Issue:3 Topics: Adolescent; Adult; Aspirin; Blood Platelet Disorders; Cephalothin; Chlorpromazine; Dexamethasone; De	1972
The effect of aspirin on the response to endotoxin. The Australian journal of experimental biology and medical science, 1972, Volume: 50, Issue:5 Topics: Animals; Aspirin; Biological Assay; Blood Cell Count; Blood Platelets; Blood Pressure; Cats; Central	1972
Aspirin poisoning. Journal of the National Medical Association, 1973, Volume: 65, Issue:6 Topics: Adult; Aspirin; Child; Drug Labeling; Female; Glucose; Humans; Male; Oxygen Inhalation Therapy; Prom	1973
Coagulopathies in septic shock. Acta chirurgica Belgica, 1973, Volume: 72, Issue:4 Topics: Animals; Aspirin; Blood Cell Count; Blood Coagulation; Blood Coagulation Disorders; Blood Coagulatio	1973
Effect of nonsteroidal anti-inflammatory drugs in endotoxin shock. Biochemical pharmacology, 1968 Topics: Animals; Anti-Inflammatory Agents; Aspirin; Blood Pressure; Depression, Chemical; Dogs; Endotoxins;	1968
Aspirin and pulmonary lesions in endotoxin shock. American heart journal, 1972, Volume: 84, Issue:4 Topics: Animals; Aspirin; Humans; Lung Diseases; Shock, Septic	1972
[Studies on the number and function of platelets in experimental endotoxic shock of the rabbit]. Beitrage zur Pathologie, 1972, Volume: 147, Issue:3 Topics: Adrenal Glands; Animals; Aspirin; Blood Cell Count; Blood Platelets; Blood Pressure; Capillary Resis	1972
Hydrogen permeability of canine gastric secretory epithelium during formation of acute superficial erosions. Surgery, 1971, Volume: 70, Issue:1 Topics: Animals; Aspirin; Biological Transport; Dogs; Female; Gastric Mucosa; Hydrogen; Male; Potassium; Sho	1971
The effects of three anti-inflammatory agents on platelet aggregation, in vitro and in vivo. Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 186, Issue:1 Topics: Animals; Anti-Inflammatory Agents; Aspirin; Azoles; Blood Platelets; Blood Pressure; Cell Aggregatio	1970
Effect of acetylsalicylic acid on the liver response to endotoxin. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1968, Volume: 127, Issue:1 Topics: Animals; Aspirin; Blood Pressure; Dogs; Endotoxins; Female; Hepatic Artery; Liver; Male; Portal Vein	1968
The protection afforded by a benzyl glucofuranoside and hydrocortisone against lethal wasp venom shock in the guinea-pig. Pharmacology, 1969, Volume: 2, Issue:1 Topics: Aminopyrine; Animals; Aspirin; Furans; Glycosides; Guinea Pigs; Hydrocortisone; Insecta; Male; Shock	1969

aspirin and Shock, Septic

Research Excerpts

Research

Studies (65)

Authors

Clinical Trials (1)

Trial Overview

Reviews

Other Studies

Authors	Studies
Saha, A	1
Khalil, S	1
Kapoor, K	1
Gupta, A	1
Dubey, NK	1
Ulu, N	1
Iskit, AB	1
Sökmensüer, C	1
Güç, MO	1
Falcone, M	2
Russo, A	1
Farcomeni, A	1
Pieralli, F	1
Vannucchi, V	1
Vullo, V	1
Violi, F	2
Venditti, M	2
Vlaović, J	1
Voga, G	1
Totani, L	1
Dell'Elba, G	1
Martelli, N	1
Di Santo, A	1
Piccoli, A	1
Amore, C	1
Evangelista, V	1
Otto, GP	1
Sossdorf, M	1
Boettel, J	1
Kabisch, B	1
Breuel, H	1
Winning, J	1
Lösche, W	1
KIMURA, Y	1
MURANAKA, M	1
Yu, Z	1
Ohtaki, Y	1
Kai, K	1
Sasano, T	1
Shimauchi, H	1
Yokochi, T	1
Takada, H	1
Sugawara, S	1
Kumagai, K	1
Endo, Y	1
Sève, P	1
Stankovic, K	1
Smail, A	1
Durand, DV	1
Marchand, G	1
Broussolle, C	1
Boccaccio, P	1
Ghio, R	1
Ratti, M	1
Casciaro, S	1
Rattenni, S	1
Sergnese, G	1
Cook, JA	4
Wise, WC	3
Butler, RR	1
Reines, HD	2
Rambo, W	1
Halushka, PV	4
Knuppel, RA	1
Rao, PS	2
Cavanagh, D	2
Horwitz, RI	1
Feinstein, AR	1
Harvey, MR	1
Fletcher, JR	3
Ramwell, PW	3
Thörnee, LJ	1
Kuenzig, M	1
Thörne, LJ	1
Gaston, LW	1
Wang, X	2
Han, C	2
Jones, SB	1
Yang, L	2
Fiscus, RR	2
Sigurdsson, GH	2
Youssef, HA	2
Owunnwanne, A	1
Abinun, M	1
Cant, AJ	1
Banic, A	1
Mourelatos, MG	1
Enzer, N	1
Ferguson, JL	1
Rypins, EB	1
Burhop, KE	1
Law, WR	1
Kilbourn, RG	1
Chan, L	1
Chinnock, B	1
Creteur, J	1
Zhang, H	1
De Backer, D	1
Sun, Q	1
Vincent, JL	1
Freeman, BD	1
Danner, RL	1
Banks, SM	1
Natanson, C	1
Freilich, E	1
Freilich, D	1
Hacker, M	1
Leach, L	1
Patel, S	1
Hebert, J	1
Saito, K	1
Siow, C	1
Endo, T	1
Kou, SZ	1
Araki, E	1
Suzuki, M	1
Okuaki, A	1
Weissbach, G	1
Farina, ML	1
Langer, M	1
Donati, MB	1
de Gaetano, G	1
Dalldorf, FG	1
Jennette, JC	1
Upton, GW	1
Tullar, JC	1
Schimmel, D	1
Schimmel, I	1
Lutter, K	1
Putsche, R	1
Herman, CM	2
Gurewich, V	1
Lipinski, B	1
Anderson, FL	1
Jubiz, W	1
Tsagaris, TJ	1
Kuida, H	1
Chen, M	1
Ichinose, Y	1
Matthias, FR	2
Ditter, H	2
Leatherman, JW	1
Schmitz, PG	1
Mikashima, H	1
Muramoto, Y	1
Bahr, T	1
Schaper, U	2
Becker, K	1
Lueddeckens, G	2
Förster, W	2
Scheuch, DW	2
Grupe, R	1
Feldhoff, CM	1
Gresele, P	1
Pieters, G	1
Vermylen, J	1
Voss, R	1
Lohmann, E	1
Fung, KP	1
Cheng, CP	1
Luey, LU	1
Loh, SC	1
Choy, YM	1
Lee, CY	1
Loadholt, CB	1
Irino, O	1
Saitoh, K	1
Ohkubo, K	1
Wang, JP	1
Hsu, MF	1
Huang, LJ	1
Nelson, NC	1
Nelson, JL	1
Weldon, WE	1
Vela, AR	1
Niklasson, PM	1
Blombäck, M	1
Lundbergh, P	1
Strandell, T	1
Bergentz, SE	2
Hall, RC	1
Hodge, RL	1
Irvine, R	1
Katic, F	1
Middleton, JM	1
Seltzer, AP	1
Erdös, EG	1
Murphy, VS	1
Greenway, CV	1
Loew, D	1
Remmele, W	1
Moody, FG	1
Aldrete, JS	1
Fleming, JS	1
Bierwagen, ME	1
Losada, M	1
Campbell, JA	1
King, SP	1
Pindell, MH	1
Solomon, LA	1
Hinshaw, LB	1
Jaques, R	1