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aspirin and Sclerosis, Systemic

aspirin has been researched along with Sclerosis, Systemic in 11 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
" With a treatment that included aspirin, heparin, and a nitric oxide donor, her third pregnancy ended with a healthy neonate at term."3.74Successful pregnancy with the use of nitric oxide donors and heparin after recurrent severe preeclampsia in a woman with scleroderma. ( Cabane, J; Carbonne, B; Cynober, E; Macé, G; Milliez, J, 2007)
" Taken together, these findings identify a previously unrecognized role of TERT in improving the immunomodulatory capacity of BMMSCs, suggesting that aspirin treatment is a practical approach to significantly reduce cell dosage in BMMSC-based immunotherapies."1.40Telomerase governs immunomodulatory properties of mesenchymal stem cells by regulating FAS ligand expression. ( Akiyama, K; Chen, C; Li, B; Shi, S; Xu, X; Yamaza, T; You, YO; Zhao, Y, 2014)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19907 (63.64)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Valentini, G1
Huscher, D1
Riccardi, A1
Fasano, S1
Irace, R1
Messiniti, V1
Matucci-Cerinic, M1
Guiducci, S1
Distler, O1
Maurer, B1
Avouac, J1
Tarner, IH1
Frerix, M1
Riemekasten, G1
Siegert, E1
Czirják, L1
Lóránd, V1
Denton, CP1
Nihtyanova, S1
Walker, UA1
Jaeger, VK1
Del Galdo, F1
Abignano, G1
Ananieva, LP1
Gherghe, AM1
Mihai, C1
Henes, JC1
Schmeiser, T1
Vacca, A1
Moiseev, S1
Foeldvari, I1
Gabrielli, A1
Krummel-Lorenz, B1
Rednic, S1
Allanore, Y1
Müeller-Ladner, U1
Varga, J1
Lee, DC1
Chen, C1
Akiyama, K1
Yamaza, T1
You, YO1
Xu, X1
Li, B1
Zhao, Y1
Shi, S1
Carbonne, B1
Macé, G1
Cynober, E1
Milliez, J1
Cabane, J1
Kahaleh, MB1
Osborn, I1
Leroy, EC1
Beckett, VL1
Conn, DL1
Fuster, V1
Osmundson, PJ1
Strong, CG1
Chao, EY1
Chesebro, JH1
O'Fallon, WM1
Bienenstock, H1
Fernando, KR1
Mannucci, PM1
Lombardi, R1
Lattuada, A1
Perticucci, E1
Valsecchi, R1
Remuzzi, G1
Grossman, JA1
Barrall, DT1
Dennison, A1
Lally, EV1
Houpt, JB1
Ogryzlo, MA1
Hunt, M1
Haslock, I1
Wright, V1

Reviews

2 reviews available for aspirin and Sclerosis, Systemic

ArticleYear
Arthritis in the elderly. An overview.
    The Medical clinics of North America, 1976, Volume: 60, Issue:6

    Topics: Adolescent; Adult; Aged; Aging; Anti-Inflammatory Agents; Arthritis; Arthritis, Infectious; Arthriti

1976
The gut and arthritis.
    Rheumatology and rehabilitation, 1974, Volume: 13, Issue:2

    Topics: Adrenal Cortex Hormones; Analgesics; Anti-Inflammatory Agents; Arthritis, Infectious; Arthritis, Rhe

1974

Trials

1 trial available for aspirin and Sclerosis, Systemic

ArticleYear
Trial of platelet-inhibiting drug in scleroderma. Double-blind study with dipyridamole and aspirin.
    Arthritis and rheumatism, 1984, Volume: 27, Issue:10

    Topics: Aspirin; Biomechanical Phenomena; Blood Coagulation; Blood Platelets; Clinical Trials as Topic; Dipy

1984

Other Studies

8 other studies available for aspirin and Sclerosis, Systemic

ArticleYear
Vasodilators and low-dose acetylsalicylic acid are associated with a lower incidence of distinct primary myocardial disease manifestations in systemic sclerosis: results of the DeSScipher inception cohort study.
    Annals of the rheumatic diseases, 2019, Volume: 78, Issue:11

    Topics: Adult; Arrhythmias, Cardiac; Aspirin; Cardiomyopathies; Female; Heart Failure; Humans; Incidence; Ma

2019
Getting to the heart of the matter: detecting and managing cardiac complications in systemic sclerosis.
    Annals of the rheumatic diseases, 2019, Volume: 78, Issue:11

    Topics: Aspirin; Cardiomyopathies; Cohort Studies; Humans; Incidence; Scleroderma, Systemic; Vasodilator Age

2019
Telomerase governs immunomodulatory properties of mesenchymal stem cells by regulating FAS ligand expression.
    EMBO molecular medicine, 2014, Volume: 6, Issue:3

    Topics: Adipogenesis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; beta Catenin; Bone Marrow C

2014
Successful pregnancy with the use of nitric oxide donors and heparin after recurrent severe preeclampsia in a woman with scleroderma.
    American journal of obstetrics and gynecology, 2007, Volume: 197, Issue:2

    Topics: Adult; Aspirin; Female; Heparin, Low-Molecular-Weight; Humans; Nitric Oxide Donors; Pre-Eclampsia; P

2007
Elevated levels of circulating platelet aggregates and beta-thromboglobulin in scleroderma.
    Annals of internal medicine, 1982, Volume: 96, Issue:5

    Topics: Aspirin; Beta-Globulins; beta-Thromboglobulin; Dipyridamole; Female; Humans; Male; Platelet Aggregat

1982
Supranormal von Willebrand factor multimers in scleroderma.
    Blood, 1989, May-01, Volume: 73, Issue:6

    Topics: Adult; Aspirin; Female; Humans; Macromolecular Substances; Male; Middle Aged; Molecular Weight; Rist

1989
Successful combined medical and surgical treatment of a lower extremity sclerodermal ulcer.
    Annals of plastic surgery, 1988, Volume: 20, Issue:6

    Topics: Aged; Aspirin; Combined Modality Therapy; Debridement; Dipyridamole; Etidronic Acid; Female; Humans;

1988
Tryptophan metabolism in man (with special reference to rheumatoid arthritis and scleroderma).
    Seminars in arthritis and rheumatism, 1973, Volume: 2, Issue:4

    Topics: Arthritis, Rheumatoid; Aspirin; Cystinuria; Drug Synergism; Edetic Acid; Humans; Kynurenic Acid; Kyn

1973