aspirin has been researched along with Schwartzman Phenomenon in 4 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Thrombin, at a dosage producing a fibrinogen consumption of 70% within 4 h (1 unit/kg/min), failed to produce extrapulmonary microthrombi unless fibrinolysis inhibition (epsilon-aminocaproic acid-EACA) or alpha-adrenergic stimulation (norepinephrine) were provided simultaneously." | 5.27 | Vasoactive agents and production of thrombosis during intravascular coagulation 1--comparative effects of norepinephrine in thrombin and adenosine diphosphate (ADP) treated rabbits. ( Daoust-Fiorilli, J; Latour, JG; Léger-Gauthier, C, 1984) |
| " Thrombin, at a dosage producing a fibrinogen consumption of 70% within 4 h (1 unit/kg/min), failed to produce extrapulmonary microthrombi unless fibrinolysis inhibition (epsilon-aminocaproic acid-EACA) or alpha-adrenergic stimulation (norepinephrine) were provided simultaneously." | 1.27 | Vasoactive agents and production of thrombosis during intravascular coagulation 1--comparative effects of norepinephrine in thrombin and adenosine diphosphate (ADP) treated rabbits. ( Daoust-Fiorilli, J; Latour, JG; Léger-Gauthier, C, 1984) |
| "The classic generalized Shwartzman reaction induced in the rabbit was prevented with large doses of aspirin (250 mg/kg) when administered at the time of the first and preparing injection of endotoxin." | 1.26 | Prevention by aspirin of the classic generalized Shwartzman reaction. ( Bernard, F; Latour, JG, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Latour, JG | 3 |
| Léger-Gauthier, C | 2 |
| Daoust-Fiorilli, J | 1 |
| Szczepański, M | 1 |
| Lucer, C | 1 |
| Staff-Zielińska, E | 1 |
| Bernard, F | 1 |
4 other studies available for aspirin and Schwartzman Phenomenon
| Article | Year |
|---|---|
Vasoactive agents and production of thrombosis during intravascular coagulation 1--comparative effects of norepinephrine in thrombin and adenosine diphosphate (ADP) treated rabbits.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aminocaproic Acid; Animals; Aspirin; Blood Coagulatio | 1984 |
Inhibitory effect of i.v. acetylsalicylic acid on the generalized shwartzman reaction in the rabbit.
Topics: Animals; Aspirin; Injections, Intravenous; Rabbits; Shwartzman Phenomenon | 1983 |
Prevention by aspirin of the classic generalized Shwartzman reaction.
Topics: Animals; Aspirin; Blood Coagulation; Disseminated Intravascular Coagulation; Endotoxins; Escherichia | 1978 |
Prostaglandins in the pathogenesis of the generalized Shwartzman reaction.
Topics: Animals; Aspirin; Bradykinin; Cortisone; Endotoxins; Female; Indomethacin; Male; Pregnancy; Prostagl | 1979 |