Page last updated: 2024-10-23

aspirin and Sarcoma

aspirin has been researched along with Sarcoma in 6 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Sarcoma: A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant.

Research Excerpts

ExcerptRelevanceReference
" The direct cytotoxicity of piroxicam indomethacin, and aspirin against 4 canine tumor cell lines (transitional cell carcinoma, squamous cell carcinoma, melanoma, and soft tissue sarcoma) was determined in short-term growth rate assays and in clonogenic assays."3.69Evaluation of in vitro cytotoxicity of nonsteroidal anti-inflammatory drugs against canine tumor cells. ( Chan, TC; Knapp, DW; Kuczek, T; Park, B; Reagan, WJ, 1995)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tuyaerts, S1
Van Nuffel, AMT1
Naert, E1
Van Dam, PA1
Vuylsteke, P1
De Caluwé, A1
Aspeslagh, S1
Dirix, P1
Lippens, L1
De Jaeghere, E1
Amant, F1
Vandecasteele, K1
Denys, H1
Patel, AR1
Crist, MK1
Nemitz, J1
Mayerson, JL1
DE DEUXCHAISNES, CN1
KRANE, SM1
Knapp, DW1
Chan, TC1
Kuczek, T1
Reagan, WJ1
Park, B1
Jaffe, BM1
Gasic, GJ1
Gasic, TB1
Galanti, N1
Johnson, T1
Murphy, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase II Investigation of Pembrolizumab (Keytruda) in Combination With Radiation and an Immune Modulatory Cocktail in Patients With Cervical and Uterine Cancer (PRIMMO Trial)[NCT03192059]Phase 243 participants (Actual)Interventional2017-07-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for aspirin and Sarcoma

ArticleYear
PAGET'S DISEASE OF BONE: CLINICAL AND METABOLIC OBSERVATIONS.
    Medicine, 1964, Volume: 43

    Topics: Alkaline Phosphatase; Aspirin; Blood; Bone and Bones; Calcium; Citrates; Fluorides; Geriatrics; Hear

1964
Prostaglandins and cancer: an update.
    Prostaglandins, 1974, Jun-25, Volume: 6, Issue:6

    Topics: Animals; Aspirin; Bucladesine; Calcium; Carcinoma; Cell Division; Cell Line; Depression, Chemical; H

1974

Trials

1 trial available for aspirin and Sarcoma

ArticleYear
PRIMMO study protocol: a phase II study combining PD-1 blockade, radiation and immunomodulation to tackle cervical and uterine cancer.
    BMC cancer, 2019, May-28, Volume: 19, Issue:1

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Aspirin; Chemoradiotherapy; Curcumin; Cycl

2019

Other Studies

3 other studies available for aspirin and Sarcoma

ArticleYear
Aspirin and compression devices versus low-molecular-weight heparin and PCD for VTE prophylaxis in orthopedic oncology patients.
    Journal of surgical oncology, 2010, Sep-01, Volume: 102, Issue:3

    Topics: Adult; Aged; Aspirin; Bone Neoplasms; Female; Heparin; Heparin, Low-Molecular-Weight; Humans; Interm

2010
Evaluation of in vitro cytotoxicity of nonsteroidal anti-inflammatory drugs against canine tumor cells.
    American journal of veterinary research, 1995, Volume: 56, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Carcinoma, Squamou

1995
Platelet-tumor-cell interactions in mice. The role of platelets in the spread of malignant disease.
    International journal of cancer, 1973, Volume: 11, Issue:3

    Topics: Adenocarcinoma; Animals; Aspirin; Blood Cell Count; Blood Platelets; Carcinoma; Cell Survival; Chrom

1973