aspirin and Sarcoma
aspirin has been researched along with Sarcoma in 6 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Sarcoma: A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " The direct cytotoxicity of piroxicam indomethacin, and aspirin against 4 canine tumor cell lines (transitional cell carcinoma, squamous cell carcinoma, melanoma, and soft tissue sarcoma) was determined in short-term growth rate assays and in clonogenic assays." | 3.69 | Evaluation of in vitro cytotoxicity of nonsteroidal anti-inflammatory drugs against canine tumor cells. ( Chan, TC; Knapp, DW; Kuczek, T; Park, B; Reagan, WJ, 1995) |
Research
Studies (6)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Tuyaerts, S | 1 |
| Van Nuffel, AMT | 1 |
| Naert, E | 1 |
| Van Dam, PA | 1 |
| Vuylsteke, P | 1 |
| De Caluwé, A | 1 |
| Aspeslagh, S | 1 |
| Dirix, P | 1 |
| Lippens, L | 1 |
| De Jaeghere, E | 1 |
| Amant, F | 1 |
| Vandecasteele, K | 1 |
| Denys, H | 1 |
| Patel, AR | 1 |
| Crist, MK | 1 |
| Nemitz, J | 1 |
| Mayerson, JL | 1 |
| DE DEUXCHAISNES, CN | 1 |
| KRANE, SM | 1 |
| Knapp, DW | 1 |
| Chan, TC | 1 |
| Kuczek, T | 1 |
| Reagan, WJ | 1 |
| Park, B | 1 |
| Jaffe, BM | 1 |
| Gasic, GJ | 1 |
| Gasic, TB | 1 |
| Galanti, N | 1 |
| Johnson, T | 1 |
| Murphy, S | 1 |
Clinical Trials (1)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase II Investigation of Pembrolizumab (Keytruda) in Combination With Radiation and an Immune Modulatory Cocktail in Patients With Cervical and Uterine Cancer (PRIMMO Trial)[NCT03192059] | Phase 2 | 43 participants (Actual) | Interventional | 2017-07-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Reviews
2 reviews available for aspirin and Sarcoma
| Article | Year |
|---|---|
PAGET'S DISEASE OF BONE: CLINICAL AND METABOLIC OBSERVATIONS.
Topics: Alkaline Phosphatase; Aspirin; Blood; Bone and Bones; Calcium; Citrates; Fluorides; Geriatrics; Hear | 1964 |
Prostaglandins and cancer: an update.
Topics: Animals; Aspirin; Bucladesine; Calcium; Carcinoma; Cell Division; Cell Line; Depression, Chemical; H | 1974 |
Trials
1 trial available for aspirin and Sarcoma
| Article | Year |
|---|---|
PRIMMO study protocol: a phase II study combining PD-1 blockade, radiation and immunomodulation to tackle cervical and uterine cancer.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Aspirin; Chemoradiotherapy; Curcumin; Cycl | 2019 |
Other Studies
3 other studies available for aspirin and Sarcoma
| Article | Year |
|---|---|
Aspirin and compression devices versus low-molecular-weight heparin and PCD for VTE prophylaxis in orthopedic oncology patients.
Topics: Adult; Aged; Aspirin; Bone Neoplasms; Female; Heparin; Heparin, Low-Molecular-Weight; Humans; Interm | 2010 |
Evaluation of in vitro cytotoxicity of nonsteroidal anti-inflammatory drugs against canine tumor cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Carcinoma, Squamou | 1995 |
Platelet-tumor-cell interactions in mice. The role of platelets in the spread of malignant disease.
Topics: Adenocarcinoma; Animals; Aspirin; Blood Cell Count; Blood Platelets; Carcinoma; Cell Survival; Chrom | 1973 |