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aspirin and Retinal Pigment Epithelial Detachment

aspirin has been researched along with Retinal Pigment Epithelial Detachment in 15 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
"Aspirin was not significantly associated with bleeding complications during or after surgery (p = 0."5.42A case-control study to assess aspirin as a risk factor of bleeding in rhegmatogenous retinal detachment surgery. ( Albaladejo, P; Aptel, F; Bernheim, D; Brillat, E; Chiquet, C; Palombi, K; Quesada, JL; Romanet, JP; Rouberol, F, 2015)
"The safety and efficacy of a new surgical method of intravitreal tamponade using silicone oil suspended with aspirin (acetylsalicylic acid) was investigated for the treatment of proliferative vitreoretinopathy."5.14Safety and feasibility of a novel intravitreal tamponade using a silicone oil/acetyl-salicylic acid suspension for proliferative vitreoretinopathy: first results of the Austrian Clinical Multicenter Study. ( Binder, S; Egger, S; Haas, A; Kieselbach, GF; Kralinger, MT; Parel, JM; Stolba, U; Velikay, M; Wedrich, A, 2010)
"We therefore examined the rate of all perioperative hemorrhages and separately the rate of only severe bleedings during vitrectomy, scleral buckling with or without drainage of subretinal fluid (SRD), or combined procedures due to retinal detachment in patients undergoing different types of perioperative anticoagulation including acetylsalicylic acetate (ASA), clopidogrel, heparin, low molecular weight heparin, and phenprocoumon."3.96Risk of perioperative bleeding complications in rhegmatogenous retinal detachment surgery: a retrospective single-center study. ( Affeldt, J; Bemme, S; Bertelmann, T; Callizo, J; Feltgen, N; Hoerauf, H; Khattab, MH; Lauermann, P; Pfeiffer, S; Striebe, NA, 2020)
" Vitreous hemorrhage occurred in 118 (35%) eyes; in 43% of patients taking aspirin, clopidogrel, or warfarin versus 31% not taking these medications (P = 0."3.79Oral anticoagulation and the risk of vitreous hemorrhage and retinal tears in eyes with acute posterior vitreous detachment. ( Cohen, SM; Witmer, MT, 2013)
" Serous retinal detachments were confirmed using fluorescein and indocyanine green angiography."3.76OCT follow-up of systemic lupus erythematosus choroidopathy. ( Bouillet, L; Chiquet, C; Kouprianoff, S; Romanet, JP, 2010)
"Aspirin was not found to have an effect on retinopathy progression or rates of vitreous hemorrhage."2.67Pars plana vitrectomy in the Early Treatment Diabetic Retinopathy Study. ETDRS report number 17. The Early Treatment Diabetic Retinopathy Study Research Group. ( Barton, FB; Chew, EY; Ferris, FL; Flynn, HW; Remaley, NA; Simons, BD, 1992)
"Aspirin was not significantly associated with bleeding complications during or after surgery (p = 0."1.42A case-control study to assess aspirin as a risk factor of bleeding in rhegmatogenous retinal detachment surgery. ( Albaladejo, P; Aptel, F; Bernheim, D; Brillat, E; Chiquet, C; Palombi, K; Quesada, JL; Romanet, JP; Rouberol, F, 2015)
"Retinal detachment was common and could neither be predicted nor prevented."1.36Treatment of acute retinal necrosis. ( Duker, JS; Maguire, JI; Morley, MG; Shah, CP; Tibbetts, MD; Young, LH, 2010)
"Proliferative vitreoretinopathy is a severe reactive process which leads to the formation of cellular membranes on the surface of the retina and in the vitreous."1.29Fibroblast growth-promoting activity in proliferative vitreoretinopathy: antagonism by acetylsalicylic acid. ( Göttinger, W; Kähler, CM; Kieselbach, GF; Reinisch, N; Troger, J; Wiedermann, CJ, 1994)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19903 (20.00)18.7374
1990's4 (26.67)18.2507
2000's1 (6.67)29.6817
2010's6 (40.00)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Bemme, S1
Lauermann, P1
Striebe, NA1
Khattab, MH1
Affeldt, J1
Callizo, J1
Bertelmann, T1
Pfeiffer, S1
Hoerauf, H1
Feltgen, N1
Arruti, M1
Aldazabal, M1
Blanco, A1
Piñeiro, L1
Zapico, MS1
González, F1
López de Munain, A1
Brillat, E1
Rouberol, F1
Palombi, K1
Quesada, JL1
Bernheim, D1
Albaladejo, P1
Aptel, F1
Romanet, JP2
Chiquet, C2
Tibbetts, MD1
Shah, CP1
Young, LH1
Duker, JS1
Maguire, JI1
Morley, MG1
Kouprianoff, S1
Bouillet, L1
Kralinger, MT1
Stolba, U1
Velikay, M1
Egger, S1
Binder, S1
Wedrich, A1
Haas, A1
Parel, JM1
Kieselbach, GF2
HOLT, KE1
Witmer, MT1
Cohen, SM1
HIGUCHI, T1
PATEL, KP1
Kähler, CM1
Reinisch, N1
Troger, J1
Göttinger, W1
Wiedermann, CJ1
Falcone, PM1
Brockhurst, RJ1
Elaxel, CJ1
Blach, RK1
Pastor, JC1
Baílez, C1
Aragón, J1
Rodríguez de la Rúa, E1
Saari, M1
Flynn, HW1
Chew, EY1
Simons, BD1
Barton, FB1
Remaley, NA1
Ferris, FL1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Challenge Test for Acetylsalicylic Acid Hypersensitivity[NCT01681615]50 participants (Anticipated)Interventional2012-09-30Not yet recruiting
[NCT00000151]Phase 30 participants Interventional1979-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for aspirin and Retinal Pigment Epithelial Detachment

ArticleYear
[Acute herpes simplex virus type 1 retinal necrosis three years after herpes simplex encephalitis].
    Revista de neurologia, 2014, Jan-01, Volume: 58, Issue:1

    Topics: Acyclovir; Antiviral Agents; Aspirin; Cataract Extraction; Causality; Drug Therapy, Combination; Enc

2014
[Treatment of the massive suprachoroidal hemorrhages].
    Archivos de la Sociedad Espanola de Oftalmologia, 2001, Volume: 76, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Blindness; Cataract Extraction; Comor

2001

Trials

2 trials available for aspirin and Retinal Pigment Epithelial Detachment

ArticleYear
Safety and feasibility of a novel intravitreal tamponade using a silicone oil/acetyl-salicylic acid suspension for proliferative vitreoretinopathy: first results of the Austrian Clinical Multicenter Study.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2010, Volume: 248, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Austria; Double-Blind Method; Drainage; Drug Combinations;

2010
Pars plana vitrectomy in the Early Treatment Diabetic Retinopathy Study. ETDRS report number 17. The Early Treatment Diabetic Retinopathy Study Research Group.
    Ophthalmology, 1992, Volume: 99, Issue:9

    Topics: Adult; Aspirin; Diabetic Retinopathy; Female; Follow-Up Studies; Humans; Laser Coagulation; Male; Mi

1992

Other Studies

11 other studies available for aspirin and Retinal Pigment Epithelial Detachment

ArticleYear
Risk of perioperative bleeding complications in rhegmatogenous retinal detachment surgery: a retrospective single-center study.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2020, Volume: 258, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Child; Child, Preschool; Clopid

2020
A case-control study to assess aspirin as a risk factor of bleeding in rhegmatogenous retinal detachment surgery.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2015, Volume: 253, Issue:11

    Topics: Aged; Aspirin; Case-Control Studies; Choroid Hemorrhage; Cryotherapy; Female; Humans; Intraoperative

2015
Treatment of acute retinal necrosis.
    Ophthalmology, 2010, Volume: 117, Issue:4

    Topics: Adult; Antiviral Agents; Aspirin; Drug Therapy, Combination; Eye Infections, Viral; Female; Glucocor

2010
OCT follow-up of systemic lupus erythematosus choroidopathy.
    Ocular immunology and inflammation, 2010, Volume: 18, Issue:2

    Topics: 4-Hydroxycoumarins; Adolescent; Adrenal Cortex Hormones; Angiography; Antibodies, Antinuclear; Aspir

2010
The separation of acetylsalicylic acid, acetophenetidin, and caffeine.
    Journal of the American Pharmaceutical Association. American Pharmaceutical Association, 1946, Volume: 35

    Topics: Aspirin; Caffeine; Phenacetin; Rare Diseases; Retinal Degeneration; Retinal Detachment; Salicylates

1946
Oral anticoagulation and the risk of vitreous hemorrhage and retinal tears in eyes with acute posterior vitreous detachment.
    Retina (Philadelphia, Pa.), 2013, Volume: 33, Issue:3

    Topics: Acute Disease; Administration, Oral; Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Clopid

2013
Separation and analysis of APC combination by partition chromatography.
    Journal of the American Pharmaceutical Association. American Pharmaceutical Association, 1952, Volume: 41, Issue:4

    Topics: Aspirin; Caffeine; Chromatography, Liquid; Phenacetin; Retinal Degeneration; Retinal Detachment

1952
Fibroblast growth-promoting activity in proliferative vitreoretinopathy: antagonism by acetylsalicylic acid.
    European journal of pharmacology, 1994, Sep-12, Volume: 262, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Arachidonic Acid; Aspirin; Cataract; Cell Division; Cells, Cultured;

1994
Delayed onset of bilateral acute retinal necrosis syndrome: a 34-year interval.
    Annals of ophthalmology, 1993, Volume: 25, Issue:10

    Topics: Acyclovir; Adolescent; Adult; Aspirin; Follow-Up Studies; Humans; Infusions, Intravenous; Longitudin

1993
Aspirin is a hazard for vitreoretinal surgery.
    The British journal of ophthalmology, 1996, Volume: 80, Issue:5

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Contraindications; Emergencies; Humans; Intr

1996
Disciform detachment of the macula. I. Juvenile haemorrhagic macular choroidopathy.
    Acta ophthalmologica, 1977, Volume: 55, Issue:3

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aspirin; Child; Choroid; Disseminated Intravascular Coag

1977