Page last updated: 2024-10-23

aspirin and Retinal Neovascularization

aspirin has been researched along with Retinal Neovascularization in 5 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Retinal Neovascularization: Formation of new blood vessels originating from the retinal veins and extending along the inner (vitreal) surface of the retina.

Research Excerpts

ExcerptRelevanceReference
"We conducted a meta-analysis of randomized controlled trials (RCTs) and observational studies to evaluate the association between aspirin use and age-related macular degeneration (AMD)."8.90Association between aspirin use and age-related macular degeneration: a meta-analysis. ( He, JJ; Lou, LX; Xu, YF; Ye, J, 2014)
"We conducted a meta-analysis of randomized controlled trials (RCTs) and observational studies to evaluate the association between aspirin use and age-related macular degeneration (AMD)."4.90Association between aspirin use and age-related macular degeneration: a meta-analysis. ( He, JJ; Lou, LX; Xu, YF; Ye, J, 2014)
" In a mouse model of hypoxia-induced retinal angiogenesis, the situation of thrombocytopenia as well as inhibition of platelet aggregation by a highly specific alphaIIbbeta3-integrin antagonist or acetyl salicylic acid (Aspirin) administration, respectively, resulted in about 35-50% reduction of retinal neovascularization, compatible with a significant contribution of blood platelets in angiogenesis."3.72The functional role of blood platelet components in angiogenesis. ( Black, M; Fischer, S; Hammes, HP; Morgenstern, E; Preissner, KT; Rhee, JS; Schubert, U, 2004)
"A therapy-resistant angle closure glaucoma following displacement of the lens-iris diaphragm due to massive choroidal and subretinal hemorrhages has rarely been reported."1.30[Acute glaucoma caused by massive subretinal hemorrhage in age-related macular degeneration and disordered thrombocyte function]. ( Hesse, L; Poller, S, 1997)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's2 (40.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ye, J1
Xu, YF1
He, JJ1
Lou, LX1
Au, A1
O'Day, J1
Rhee, JS1
Black, M1
Schubert, U1
Fischer, S1
Morgenstern, E1
Hammes, HP1
Preissner, KT1
Poller, S1
Hesse, L1
Nobacht, S1
Cruysberg, JR1
Deutman, AF1

Reviews

2 reviews available for aspirin and Retinal Neovascularization

ArticleYear
Association between aspirin use and age-related macular degeneration: a meta-analysis.
    Investigative ophthalmology & visual science, 2014, Apr-25, Volume: 55, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Global Health; Humans; Incidence; Macular Degenera

2014
Review of severe vaso-occlusive retinopathy in systemic lupus erythematosus and the antiphospholipid syndrome: associations, visual outcomes, complications and treatment.
    Clinical & experimental ophthalmology, 2004, Volume: 32, Issue:1

    Topics: Adult; Antibodies, Antiphospholipid; Anticoagulants; Antiphospholipid Syndrome; Aspirin; Combined Mo

2004

Other Studies

3 other studies available for aspirin and Retinal Neovascularization

ArticleYear
The functional role of blood platelet components in angiogenesis.
    Thrombosis and haemostasis, 2004, Volume: 92, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Component Transfusion; Blood Platel

2004
[Acute glaucoma caused by massive subretinal hemorrhage in age-related macular degeneration and disordered thrombocyte function].
    Klinische Monatsblatter fur Augenheilkunde, 1997, Volume: 210, Issue:6

    Topics: Acetaminophen; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Eye Enucleation; Female; Glau

1997
Peripheral retinal nonperfusion associated with essential thrombocytosis.
    American journal of ophthalmology, 1999, Volume: 127, Issue:1

    Topics: Adult; Arteriovenous Anastomosis; Aspirin; Fluorescein Angiography; Fundus Oculi; Humans; Laser Coag

1999