aspirin has been researched along with Retinal Degeneration in 11 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Retinal Degeneration: A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To characterize the effect of aspirin (ASA) in mouse models of choroidal neovascularization (CNV) and retinal degeneration." | 3.83 | Effect of aspirin on models of retinal pigment epithelium pathology. ( Ali, O; Bora, NS; Bora, PS; Goyal, S; Lyzogubov, VV; Uwaydat, SH, 2016) |
| "Daily administration of acetyl salicylic acid (ASA) and ibuprofen leads to an appreciable retardation in the process of retinal degeneration in the RCS rat which is dependent on the dosage given." | 3.68 | [The effect of cyclooxygenase inhibitors on the course of hereditary retinal dystrophy in RCS rats]. ( el-Hifnawi, ES; Haug, H; Kühnel, W; Laqua, H; Orün, C, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (81.82) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goyal, S | 1 |
| Lyzogubov, VV | 1 |
| Ali, O | 1 |
| Bora, PS | 1 |
| Bora, NS | 1 |
| Uwaydat, SH | 1 |
| HOLT, KE | 1 |
| HIGUCHI, T | 1 |
| PATEL, KP | 1 |
| Dewar, AJ | 4 |
| Barron, G | 3 |
| Reading, HW | 3 |
| Riding, GV | 1 |
| Mosier, JE | 1 |
| el-Hifnawi, ES | 1 |
| Kühnel, W | 2 |
| Orün, C | 1 |
| Haug, H | 1 |
| Laqua, H | 1 |
| el-Hifnawi, E | 1 |
1 review available for aspirin and Retinal Degeneration
| Article | Year |
|---|---|
[Lysosomes, cyclic nucleotides and retinal degeneration].
Topics: Animals; Aspirin; Cortisone; Cyclic AMP; Cyclic GMP; Darkness; DNA; Lysosomes; Mice; Nucleotides, Cy | 1978 |
10 other studies available for aspirin and Retinal Degeneration
| Article | Year |
|---|---|
Effect of aspirin on models of retinal pigment epithelium pathology.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Line; Chemokine CCL2; Choroidal Neov | 2016 |
The separation of acetylsalicylic acid, acetophenetidin, and caffeine.
Topics: Aspirin; Caffeine; Phenacetin; Rare Diseases; Retinal Degeneration; Retinal Detachment; Salicylates | 1946 |
Separation and analysis of APC combination by partition chromatography.
Topics: Aspirin; Caffeine; Chromatography, Liquid; Phenacetin; Retinal Degeneration; Retinal Detachment | 1952 |
The effect of anti-inflammatory drugs on retinal dystrophy in the rat.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cortisone; Light; Rats; Retina; Retinal Degeneration; Sa | 1977 |
Common medical and behavioral problems in cats.
Topics: Aggression; Animals; Anxiety; Aspirin; Behavior, Animal; Blood Specimen Collection; Blood Transfusio | 1975 |
The effects of excess vitamin A and acetylsalicylic acid on the stability of rat retinal lysosomes in vivo.
Topics: Animals; Aspirin; Galactosidases; Hexosaminidases; Lysosomes; Rats; Retina; Retinal Degeneration; Vi | 1977 |
The role of retinol in, and the action of anti-inflammatory drugs on, hereditary retinal degeneration.
Topics: Acid Phosphatase; Animals; Aspirin; Darkness; DNA; Female; Galactosidases; Genes, Recessive; Glucuro | 1975 |
The effect of retinol and acetylsalicylic acid on the release of lysosomal enzymes from rat retina in vitro.
Topics: Animals; Aspirin; Female; Galactosidases; Glucuronidase; Hexosaminidases; In Vitro Techniques; Lysos | 1975 |
[The effect of cyclooxygenase inhibitors on the course of hereditary retinal dystrophy in RCS rats].
Topics: Animals; Animals, Newborn; Aspirin; Cell Nucleus; Ibuprofen; Microscopy, Electron; Phagosomes; Photo | 1992 |
The effect of anti-inflammatory drug administration on the course of retinal dystrophy in RCS rats.
Topics: Aging; Animals; Aspirin; Female; Male; Phagocytosis; Photoreceptor Cells; Pigment Epithelium of Eye; | 1989 |