aspirin has been researched along with Respiratory Distress Syndrome in 42 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Respiratory Distress Syndrome: A syndrome characterized by progressive life-threatening RESPIRATORY INSUFFICIENCY in the absence of known LUNG DISEASES, usually following a systemic insult such as surgery or major TRAUMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To test the hypothesis that aspirin reduces inflammation in clinically relevant human models that recapitulate pathophysiological mechanisms implicated in the development of ARDS." | 9.24 | Aspirin reduces lipopolysaccharide-induced pulmonary inflammation in human models of ARDS. ( Fitzgerald, M; Hamid, U; Kissenpfennig, A; Krasnodembskaya, A; Lefrancais, E; Looney, MR; McAuley, DF; McNamee, J; O'Kane, CM; Scott, C; Scott, J; Shyamsundar, M; Simpson, AJ; Verghis, R, 2017) |
| "The effects of aspirin in preventing the occurrence of acute respiratory distress syndrome (ARDS)/acute lung injury (ALI) among adult patients are controversial." | 8.98 | The effect of aspirin in preventing the acute respiratory distress syndrome/acute lung injury: A meta-analysis. ( Liang, BM; Liang, ZA; Ni, YN; Wang, Y; Yu, H, 2018) |
| "It has been suggested that aspirin may be of benefit in treating sepsis and ARDS in view of its ability to block cyclo-oxygenase-1 (COX-1) and COX-2 activities; inhibit nuclear factor kappa B (NF-κB); enhance the production of endothelial nitric oxide (eNO) and lipoxin A4 (LXA4)." | 8.93 | Combination of aspirin with essential fatty acids is superior to aspirin alone to prevent or ameliorate sepsis or ARDS. ( Das, UN, 2016) |
| "Of 1,149 patients, 368 (32%) developed acute respiratory distress syndrome during the first 4 ICU days and 287 (25%) patients had prehospital aspirin use." | 7.81 | Prehospital aspirin use is associated with reduced risk of acute respiratory distress syndrome in critically ill patients: a propensity-adjusted analysis. ( Bastarache, JA; Bernard, GR; Chen, W; Janz, DR; May, AK; O'Neal, HR; Ware, LB, 2015) |
| " A multivariable analysis including age, gender, current tobacco use, prehospital aspirin use, race, and Acute Physiology and Chronic Health Evaluation II score revealed that patients on statin therapy before hospitalization were less likely to have or develop severe sepsis (odds ratio 0." | 7.77 | Prehospital statin and aspirin use and the prevalence of severe sepsis and acute lung injury/acute respiratory distress syndrome. ( Bernard, GR; Curtis, BR; Fremont, RD; Koehler, EA; Koyama, T; May, AK; O'Neal, HR; Siew, E; Ware, LB, 2011) |
| "Aspirin has been reported to induce the adult respiratory distress syndrome (ARDS) in humans." | 7.67 | Bronchoalveolar lavage in recurrent aspirin-induced adult respiratory distress syndrome. ( Krieger, BP; Suarez, M, 1986) |
| "Sepsis is a common condition that is associated with significant morbidity, mortality and health-care cost." | 6.52 | Aspirin as a potential treatment in sepsis or acute respiratory distress syndrome. ( McAuley, DF; Shyamsundar, M; Toner, P, 2015) |
| "Aspirin therapy was associated with a reduced risk of ICU mortality." | 5.42 | Aspirin therapy in patients with acute respiratory distress syndrome (ARDS) is associated with reduced intensive care unit mortality: a prospective analysis. ( Boyle, AJ; Cross, LJ; Di Gangi, S; Hamid, UI; McAuley, DF; McNamee, JJ; McNamee, L; Mottram, LJ; O'Kane, CM; White, G, 2015) |
| "Ticlopidine is an antiplatelet agent that has been proven efficacious in preventing vascular events in patients with a history of vasculopathy." | 5.30 | Ticlopidine-associated pancytopenia: implications of an acetylsalicylic acid alternative. ( Armstrong, PW; Brown, NE; Gill, S; Majumdar, S, 1997) |
| "To test the hypothesis that aspirin reduces inflammation in clinically relevant human models that recapitulate pathophysiological mechanisms implicated in the development of ARDS." | 5.24 | Aspirin reduces lipopolysaccharide-induced pulmonary inflammation in human models of ARDS. ( Fitzgerald, M; Hamid, U; Kissenpfennig, A; Krasnodembskaya, A; Lefrancais, E; Looney, MR; McAuley, DF; McNamee, J; O'Kane, CM; Scott, C; Scott, J; Shyamsundar, M; Simpson, AJ; Verghis, R, 2017) |
| " The aspirin is useful to reduce mortality of serious patients with acute respiratory distress syndrome without COVID-19." | 5.12 | Use of aspirin in reduction of mortality of COVID-19 patients: A meta-analysis. ( Kumar, A; Srivastava, R, 2021) |
| "The effects of aspirin in preventing the occurrence of acute respiratory distress syndrome (ARDS)/acute lung injury (ALI) among adult patients are controversial." | 4.98 | The effect of aspirin in preventing the acute respiratory distress syndrome/acute lung injury: A meta-analysis. ( Liang, BM; Liang, ZA; Ni, YN; Wang, Y; Yu, H, 2018) |
| "It has been suggested that aspirin may be of benefit in treating sepsis and ARDS in view of its ability to block cyclo-oxygenase-1 (COX-1) and COX-2 activities; inhibit nuclear factor kappa B (NF-κB); enhance the production of endothelial nitric oxide (eNO) and lipoxin A4 (LXA4)." | 4.93 | Combination of aspirin with essential fatty acids is superior to aspirin alone to prevent or ameliorate sepsis or ARDS. ( Das, UN, 2016) |
| "Of 1,149 patients, 368 (32%) developed acute respiratory distress syndrome during the first 4 ICU days and 287 (25%) patients had prehospital aspirin use." | 3.81 | Prehospital aspirin use is associated with reduced risk of acute respiratory distress syndrome in critically ill patients: a propensity-adjusted analysis. ( Bastarache, JA; Bernard, GR; Chen, W; Janz, DR; May, AK; O'Neal, HR; Ware, LB, 2015) |
| " A multivariable analysis including age, gender, current tobacco use, prehospital aspirin use, race, and Acute Physiology and Chronic Health Evaluation II score revealed that patients on statin therapy before hospitalization were less likely to have or develop severe sepsis (odds ratio 0." | 3.77 | Prehospital statin and aspirin use and the prevalence of severe sepsis and acute lung injury/acute respiratory distress syndrome. ( Bernard, GR; Curtis, BR; Fremont, RD; Koehler, EA; Koyama, T; May, AK; O'Neal, HR; Siew, E; Ware, LB, 2011) |
| "Aspirin has been reported to induce the adult respiratory distress syndrome (ARDS) in humans." | 3.67 | Bronchoalveolar lavage in recurrent aspirin-induced adult respiratory distress syndrome. ( Krieger, BP; Suarez, M, 1986) |
| "Aspirin was well tolerated but did not improve OI or other physiological outcomes; a larger trial is not feasible in its current design." | 3.11 | Aspirin as a Treatment for ARDS: A Randomized, Placebo-Controlled Clinical Trial. ( Boyle, AJ; Callaghan, K; Johnston, P; McAuley, DF; McFarland, M; McNamee, JJ; Nutt, C; O'Kane, CM; Toner, P; Trinder, J; Verghis, R, 2022) |
| "Management of acute respiratory distress syndrome (ARDS) remains largely supportive." | 2.82 | Effect of Aspirin on Development of ARDS in At-Risk Patients Presenting to the Emergency Department: The LIPS-A Randomized Clinical Trial. ( Banner-Goodspeed, VM; Carter, RE; Festic, E; Gajic, O; Gong, MN; Hinds, R; Kor, DJ; Park, PK; Talmor, D; Ware, LB, 2016) |
| "Sepsis is a common condition that is associated with significant morbidity, mortality and health-care cost." | 2.52 | Aspirin as a potential treatment in sepsis or acute respiratory distress syndrome. ( McAuley, DF; Shyamsundar, M; Toner, P, 2015) |
| "The results of treatment of the fat embolism syndrome should improve if there is a realization that even relatively uncomplicated fractures of the extremities cause significant metabolic, platelet, coagulation and pulmonary changes." | 2.36 | Fat embolism syndrome: traumatic coagulopathy with respiratory distress. ( Shier, MR; Wilson, RF, 1980) |
| "Aspirin is a well-known anti-platelet drug widely used for the prevention of cardiovascular events and systematic reviews suggest a possible benefit of low-dose aspirin (LDA) use in the prevention and treatment of ARDS in patients with COVID-19 infection." | 1.91 | Low dose aspirin and clinical outcomes in patients with SARS-CoV-2 pneumonia: a propensity score-matched cohort analysis from the National SIMI‑COVID‑19 Registry. ( Cimellaro, A; Daidone, M; Dalbeni, A; Giontella, A; Pietrangelo, A; Rossi, I; Sesti, G; Susca, N; Talerico, G; Villani, R; Zaccone, V, 2023) |
| "Immunological TRALI was tested in mice exhibiting severe thrombocytopenia or platelet dysfunction." | 1.43 | Platelets are dispensable for antibody-mediated transfusion-related acute lung injury in the mouse. ( de la Salle, H; El Mdawar, MB; Gachet, C; Hechler, B; Heim, V; Magnenat, S; Maître, B, 2016) |
| "We sought to determine the prevalence of acute respiratory distress syndrome after intracerebral hemorrhage, characterize risk factors for its development, and assess its impact on patient outcomes." | 1.39 | Acute respiratory distress syndrome after spontaneous intracerebral hemorrhage*. ( Avery, L; Bajwa, E; Camargo, CA; Chang, Y; Duran-Mendicuti, MA; Elmer, J; Goldstein, JN; Greenberg, SM; Hess, DR; Hou, P; Okechukwu, I; Pallin, DJ; Pontes-Neto, O; Rosand, J; Schreiber, H; Wilcox, SR, 2013) |
| "Ticlopidine is an antiplatelet agent that has been proven efficacious in preventing vascular events in patients with a history of vasculopathy." | 1.30 | Ticlopidine-associated pancytopenia: implications of an acetylsalicylic acid alternative. ( Armstrong, PW; Brown, NE; Gill, S; Majumdar, S, 1997) |
| "We report here adult respiratory distress syndrome (ARDS) in a 54-year-old man found to have salicylate toxicity one day after admission to the alcohol detoxification service at a community hospital." | 1.27 | Adult respiratory distress syndrome induced by salicylate toxicity. ( Baltatzis, PA; Niehoff, JM, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (21.43) | 18.7374 |
| 1990's | 3 (7.14) | 18.2507 |
| 2000's | 3 (7.14) | 29.6817 |
| 2010's | 21 (50.00) | 24.3611 |
| 2020's | 6 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Toner, P | 2 |
| Boyle, AJ | 2 |
| McNamee, JJ | 2 |
| Callaghan, K | 1 |
| Nutt, C | 1 |
| Johnston, P | 1 |
| Trinder, J | 1 |
| McFarland, M | 1 |
| Verghis, R | 2 |
| McAuley, DF | 4 |
| O'Kane, CM | 3 |
| Chakraborty, N | 1 |
| Muzaffar, SN | 1 |
| Siddiqui, SS | 1 |
| Dalbeni, A | 1 |
| Susca, N | 1 |
| Daidone, M | 1 |
| Rossi, I | 1 |
| Giontella, A | 1 |
| Cimellaro, A | 1 |
| Talerico, G | 1 |
| Pietrangelo, A | 1 |
| Sesti, G | 1 |
| Zaccone, V | 1 |
| Villani, R | 1 |
| Hope, AA | 1 |
| Chen, JT | 1 |
| Kaufman, DA | 1 |
| Talmor, DS | 1 |
| Kor, DJ | 3 |
| Gajic, O | 2 |
| Gong, MN | 3 |
| Jin, W | 1 |
| Chuang, CC | 1 |
| Jin, H | 1 |
| Ye, J | 1 |
| Kandaswamy, E | 1 |
| Wang, L | 1 |
| Zuo, L | 1 |
| Coppola, S | 1 |
| Chiumello, D | 1 |
| Srivastava, R | 1 |
| Kumar, A | 1 |
| Du, F | 1 |
| Jiang, P | 1 |
| He, S | 1 |
| Song, D | 1 |
| Xu, F | 1 |
| Beloncle, F | 1 |
| Mercat, A | 1 |
| Foong, NZE | 1 |
| Yii, ACA | 1 |
| Hsu, AAL | 1 |
| Yu, H | 1 |
| Ni, YN | 1 |
| Liang, ZA | 1 |
| Liang, BM | 1 |
| Wang, Y | 1 |
| Elmer, J | 1 |
| Hou, P | 1 |
| Wilcox, SR | 1 |
| Chang, Y | 1 |
| Schreiber, H | 1 |
| Okechukwu, I | 1 |
| Pontes-Neto, O | 1 |
| Bajwa, E | 1 |
| Hess, DR | 1 |
| Avery, L | 1 |
| Duran-Mendicuti, MA | 1 |
| Camargo, CA | 1 |
| Greenberg, SM | 1 |
| Rosand, J | 1 |
| Pallin, DJ | 1 |
| Goldstein, JN | 1 |
| Chen, W | 1 |
| Janz, DR | 1 |
| Bastarache, JA | 1 |
| May, AK | 2 |
| O'Neal, HR | 2 |
| Bernard, GR | 2 |
| Ware, LB | 3 |
| Palakshappa, JA | 1 |
| Christie, JD | 2 |
| Di Gangi, S | 1 |
| Hamid, UI | 1 |
| Mottram, LJ | 1 |
| McNamee, L | 1 |
| White, G | 1 |
| Cross, LJ | 1 |
| Mazzeffi, M | 1 |
| Kassa, W | 1 |
| Gammie, J | 1 |
| Tanaka, K | 1 |
| Roman, P | 1 |
| Zhan, M | 1 |
| Griffith, B | 1 |
| Rock, P | 1 |
| Shyamsundar, M | 2 |
| Hechler, B | 1 |
| Maître, B | 1 |
| Magnenat, S | 1 |
| Heim, V | 1 |
| El Mdawar, MB | 1 |
| Gachet, C | 1 |
| de la Salle, H | 1 |
| Reilly, JP | 1 |
| Carter, RE | 1 |
| Park, PK | 1 |
| Festic, E | 1 |
| Banner-Goodspeed, VM | 1 |
| Hinds, R | 1 |
| Talmor, D | 1 |
| Kuschner, RA | 1 |
| Levy, BD | 1 |
| Das, UN | 1 |
| Panka, BA | 1 |
| de Grooth, HJ | 1 |
| Spoelstra-de Man, AM | 1 |
| Looney, MR | 2 |
| Tuinman, PR | 1 |
| Hamid, U | 1 |
| Krasnodembskaya, A | 1 |
| Fitzgerald, M | 1 |
| Kissenpfennig, A | 1 |
| Scott, C | 1 |
| Lefrancais, E | 1 |
| Scott, J | 1 |
| Simpson, AJ | 1 |
| McNamee, J | 1 |
| Koyama, T | 1 |
| Koehler, EA | 1 |
| Siew, E | 1 |
| Curtis, BR | 1 |
| Fremont, RD | 1 |
| Somma, MM | 1 |
| Weinstock, PJ | 1 |
| Muzaffar, S | 1 |
| Shukla, N | 1 |
| Angelini, G | 1 |
| Jeremy, JY | 1 |
| Yu, Z | 1 |
| Ohtaki, Y | 1 |
| Kai, K | 1 |
| Sasano, T | 1 |
| Shimauchi, H | 1 |
| Yokochi, T | 1 |
| Takada, H | 1 |
| Sugawara, S | 1 |
| Kumagai, K | 1 |
| Endo, Y | 1 |
| Knowles, SR | 1 |
| Drucker, AM | 1 |
| Weber, EA | 1 |
| Shear, NH | 1 |
| López Pastor, A | 1 |
| Martínez Ramos, C | 1 |
| García Muñoz, S | 1 |
| Gutstein Feldman, D | 1 |
| Vara Thorbeck, C | 1 |
| Shier, MR | 1 |
| Wilson, RF | 1 |
| Stover, D | 1 |
| Lippmann, M | 1 |
| Eliraz, A | 1 |
| Curtius, JM | 1 |
| Goeckenjan, G | 1 |
| Steyer, M | 1 |
| Hust, M | 1 |
| Gill, S | 1 |
| Majumdar, S | 1 |
| Brown, NE | 1 |
| Armstrong, PW | 1 |
| Bray, PF | 1 |
| Kahn, A | 1 |
| Blum, D | 1 |
| Andersen, R | 1 |
| Refstad, S | 1 |
| Ichinose, Y | 1 |
| Sigurdsson, GH | 1 |
| Vallgren, S | 1 |
| Christenson, JT | 1 |
| Suarez, M | 1 |
| Krieger, BP | 1 |
| Niehoff, JM | 1 |
| Baltatzis, PA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| ASpirin as a Treatment for ARDS (STAR): a Phase 2 Randomised Control Trial[NCT02326350] | Phase 2 | 49 participants (Actual) | Interventional | 2015-02-06 | Terminated (stopped due to Slow recruitment) | ||
| The Effect of Aspirin on REducing iNflammation in Human in Vivo Model of Acute Lung Injury[NCT01659307] | Phase 2 | 33 participants (Anticipated) | Interventional | 2012-09-30 | Completed | ||
| LIPS-A: Lung Injury Prevention Study With Aspirin[NCT01504867] | Phase 2 | 400 participants (Actual) | Interventional | 2012-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT01504867)
Timeframe: 28 days
| Intervention | participants (Number) |
|---|---|
| Aspirin | 14 |
| Placebo | 14 |
(NCT01504867)
Timeframe: approximately 7 days
| Intervention | days (Mean) |
|---|---|
| Aspirin | 8.8 |
| Placebo | 9.0 |
(NCT01504867)
Timeframe: baseline, Day 28
| Intervention | days (Mean) |
|---|---|
| Aspirin | 24.9 |
| Placebo | 25.2 |
ARDS was defined by Berlin criteria (modified to require invasive mechanical ventilation) within 7 days of hospital admission. (NCT01504867)
Timeframe: Within seven days from hospital presentation
| Intervention | participants (Number) |
|---|---|
| Aspirin | 20 |
| Placebo | 17 |
(NCT01504867)
Timeframe: within 7 days
| Intervention | participants (Number) |
|---|---|
| Aspirin | 27 |
| Placebo | 21 |
(NCT01504867)
Timeframe: 7 days
| Intervention | participants (Number) |
|---|---|
| Aspirin | 115 |
| Placebo | 98 |
(NCT01504867)
Timeframe: approximately 7 days
| Intervention | participants (Number) |
|---|---|
| Aspirin | 51 |
| Placebo | 41 |
10 reviews available for aspirin and Respiratory Distress Syndrome
| Article | Year |
|---|---|
Effects of Pre-Hospital Antiplatelet Therapy on the Incidence of ARDS.
Topics: Aspirin; Hospitals; Humans; Incidence; Platelet Aggregation Inhibitors; Prospective Studies; Respira | 2020 |
Use of aspirin in reduction of mortality of COVID-19 patients: A meta-analysis.
Topics: Aspirin; COVID-19; Humans; Respiratory Distress Syndrome; SARS-CoV-2 | 2021 |
Antiplatelet Therapy for Critically Ill Patients: A Pairwise and Bayesian Network Meta-Analysis.
Topics: Acute Lung Injury; Aspirin; Critical Illness; Hospital Mortality; Humans; Incidence; Network Meta-An | 2018 |
Approaches and techniques to avoid development or progression of acute respiratory distress syndrome.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biomarkers; Critical Care | 2018 |
The effect of aspirin in preventing the acute respiratory distress syndrome/acute lung injury: A meta-analysis.
Topics: Acute Lung Injury; Aspirin; Humans; Randomized Controlled Trials as Topic; Respiratory Distress Synd | 2018 |
Aspirin as a potential treatment in sepsis or acute respiratory distress syndrome.
Topics: Aspirin; Humans; Lung; Platelet Activation; Respiratory Distress Syndrome; Sepsis | 2015 |
Aspirin as a potential treatment in sepsis or acute respiratory distress syndrome.
Topics: Aspirin; Humans; Lung; Platelet Activation; Respiratory Distress Syndrome; Sepsis | 2015 |
Aspirin as a potential treatment in sepsis or acute respiratory distress syndrome.
Topics: Aspirin; Humans; Lung; Platelet Activation; Respiratory Distress Syndrome; Sepsis | 2015 |
Aspirin as a potential treatment in sepsis or acute respiratory distress syndrome.
Topics: Aspirin; Humans; Lung; Platelet Activation; Respiratory Distress Syndrome; Sepsis | 2015 |
Combination of aspirin with essential fatty acids is superior to aspirin alone to prevent or ameliorate sepsis or ARDS.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Drug Therapy, Combination; Eicos | 2016 |
Prevention or Treatment of Ards With Aspirin: A Review of Preclinical Models and Meta-Analysis of Clinical Studies.
Topics: Animals; Aspirin; Humans; Platelet Activation; Respiratory Distress Syndrome | 2017 |
Management options for patients with aspirin and nonsteroidal antiinflammatory drug sensitivity.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Disease Management; Drug Hypersensitivity; Humans; | 2007 |
Fat embolism syndrome: traumatic coagulopathy with respiratory distress.
Topics: Adrenal Cortex Hormones; Aspirin; Blood Coagulation Disorders; Blood Platelets; Cholesterol; Embolis | 1980 |
4 trials available for aspirin and Respiratory Distress Syndrome
| Article | Year |
|---|---|
Aspirin as a Treatment for ARDS: A Randomized, Placebo-Controlled Clinical Trial.
Topics: Adult; Aspirin; COVID-19; Double-Blind Method; Humans; Intensive Care Units; Respiration, Artificial | 2022 |
The Association between Prehospital Vulnerability, ARDS Development, and Mortality among At-Risk Adults. Results from the LIPS-A Clinical Trial.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Emergency Service, Hospital; Female; | 2019 |
Effect of Aspirin on Development of ARDS in At-Risk Patients Presenting to the Emergency Department: The LIPS-A Randomized Clinical Trial.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Double-Blind Method; Emergency Servic | 2016 |
Aspirin reduces lipopolysaccharide-induced pulmonary inflammation in human models of ARDS.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biomarkers; Bronchoalveolar Lavage; C-React | 2017 |
28 other studies available for aspirin and Respiratory Distress Syndrome
| Article | Year |
|---|---|
Aspirin Cannot Stop Multiple Pathophysiologic Pathways of ARDS.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Respiratory Distress Syndrome | 2022 |
Low dose aspirin and clinical outcomes in patients with SARS-CoV-2 pneumonia: a propensity score-matched cohort analysis from the National SIMI‑COVID‑19 Registry.
Topics: Aged; Aged, 80 and over; Aspirin; Cohort Studies; COVID-19; Female; Humans; Male; Multicenter Studie | 2023 |
Aspirin in Coronavirus Disease 2019-Related Acute Respiratory Distress Syndrome: An Old, Low-Cost Therapy With a Strong Rationale.
Topics: Aspirin; COVID-19; Hospital Mortality; Humans; Intensive Care Units; Respiration, Artificial; Respir | 2021 |
Severe life-threatening asthma precipitated by a topical nonsteroidal anti-inflammatory drug.
Topics: Administration, Cutaneous; Adrenal Cortex Hormones; Adult; Albuterol; Aspirin; Asthma, Aspirin-Induc | 2018 |
Acute respiratory distress syndrome after spontaneous intracerebral hemorrhage*.
Topics: Acute Lung Injury; Aged; Aspirin; Cerebral Hemorrhage; Cohort Studies; Erythrocyte Transfusion; Fema | 2013 |
Prehospital aspirin use is associated with reduced risk of acute respiratory distress syndrome in critically ill patients: a propensity-adjusted analysis.
Topics: Aged; Aspirin; Cohort Studies; Critical Illness; Female; Humans; Male; Middle Aged; Respiratory Dist | 2015 |
Prehospital aspirin use and acute respiratory distress syndrome--a case for aspirin in the drinking water?
Topics: Aspirin; Critical Illness; Female; Humans; Male; Respiratory Distress Syndrome | 2015 |
Aspirin therapy in patients with acute respiratory distress syndrome (ARDS) is associated with reduced intensive care unit mortality: a prospective analysis.
Topics: Aspirin; Hospital Mortality; Humans; Intensive Care Units; Odds Ratio; Platelet Aggregation Inhibito | 2015 |
Preoperative Aspirin Use and Lung Injury After Aortic Valve Replacement Surgery: A Retrospective Cohort Study.
Topics: Aged; Aged, 80 and over; Aortic Valve; Aspirin; Baltimore; Drug Administration Schedule; Female; Hea | 2015 |
Platelets are dispensable for antibody-mediated transfusion-related acute lung injury in the mouse.
Topics: Animals; Antibodies, Monoclonal; Aspirin; Blood Platelets; Blood Transfusion; Clopidogrel; Diphtheri | 2016 |
Is It Possible to Prevent ARDS?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Humans; Male; Respiratory Distress Syndrom | 2016 |
Aspirin and Acute Respiratory Distress Syndrome.
Topics: Aspirin; Humans; Respiration, Artificial; Respiratory Distress Syndrome | 2016 |
Aspirin and Acute Respiratory Distress Syndrome-Reply.
Topics: Aspirin; Humans; Respiration, Artificial; Respiratory Distress Syndrome | 2016 |
Prehospital statin and aspirin use and the prevalence of severe sepsis and acute lung injury/acute respiratory distress syndrome.
Topics: Acute Lung Injury; Aged; Aspirin; Cohort Studies; Cross-Sectional Studies; Female; Humans; Hydroxyme | 2011 |
Statins and sepsis: a magic bullet or just shooting blanks?
Topics: Acute Lung Injury; Aspirin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Platelet Aggrega | 2011 |
Nitroaspirins and morpholinosydnonimine but not aspirin inhibit the formation of superoxide and the expression of gp91phox induced by endotoxin and cytokines in pig pulmonary artery vascular smooth muscle cells and endothelial cells.
Topics: Acetophenones; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Evaluation, Preclinic | 2004 |
Critical roles of platelets in lipopolysaccharide-induced lethality: effects of glycyrrhizin and possible strategy for acute respiratory distress syndrome.
Topics: Animals; Antibodies, Monoclonal; Aspirin; Blood Platelets; Dexamethasone; Glycyrrhizic Acid; Lipopol | 2005 |
[Antiaggregant drugs in traumatic shock lung. Experimental study].
Topics: Animals; Anticoagulants; Aspirin; Crush Syndrome; Dipyridamole; Female; Lung; Male; Platelet Aggrega | 1984 |
[Adult respiratory distress syndrome and aspirin intoxication].
Topics: Aspirin; Female; Humans; Middle Aged; Respiratory Distress Syndrome | 1982 |
[Pulmonary oedema as a complication of tocolytic therapy (author's transl)].
Topics: Adult; Aspirin; Autopsy; Betamethasone; Ethanolamines; Female; Fenoterol; Humans; Obstetric Labor, P | 1980 |
Ticlopidine-associated pancytopenia: implications of an acetylsalicylic acid alternative.
Topics: Aspirin; Cardiovascular Diseases; Drug Resistance; Fatal Outcome; Female; Humans; Middle Aged; Neutr | 1997 |
Are we still abusing aspirin?
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Humans; Multiple Organ Failure; Plate | 1998 |
Fatal respiratory-distress syndrome and salicylate intoxication in a two-year-old.
Topics: Aspirin; Child, Preschool; Female; Humans; Pulmonary Edema; Respiratory Distress Syndrome | 1979 |
Adult respiratory distress syndrome precipitated by massive salicylate poisoning.
Topics: Aspirin; Blood Coagulation; Carbon Dioxide; Humans; Male; Middle Aged; Oxygen; Respiratory Distress | 1978 |
[Adult respiratory distress syndrome (ARDS)].
Topics: Adult; Aged; Aged, 80 and over; Aprotinin; Aspirin; Disseminated Intravascular Coagulation; Female; | 1990 |
Influence of aspirin and steroids on acute lung injury after i.v. Injection of a sclerosing agent.
Topics: Animals; Aspirin; Drug Evaluation; Hemodynamics; Injections, Intravenous; Methylprednisolone; Oleic | 1989 |
Bronchoalveolar lavage in recurrent aspirin-induced adult respiratory distress syndrome.
Topics: Aspirin; Humans; Leukocytes; Male; Middle Aged; Pulmonary Alveoli; Pulmonary Edema; Recurrence; Resp | 1986 |
Adult respiratory distress syndrome induced by salicylate toxicity.
Topics: Aspirin; Humans; Male; Middle Aged; Respiratory Distress Syndrome; Salicylates | 1985 |