aspirin has been researched along with Respiration Disorders in 29 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Respiration Disorders: Diseases of the respiratory system in general or unspecified or for a specific respiratory disease not available.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine any benefits or risks, expressed in early childhood, of low dose aspirin treatment in pregnancies at high risk of complications due to pre-eclampsia or intrauterine growth retardation." | 9.08 | Low dose aspirin in pregnancy and early childhood development: follow up of the collaborative low dose aspirin study in pregnancy. CLASP collaborative group. ( , 1995) |
| "Aspirin-exacerbated respiratory disease (AERD) is a clinical condition which results in adverse upper and lower respiratory symptoms, particularly rhinitis, conjunctivitis, bronchospasm, and/or laryngospasm, following exposure to cyclooxygenase-1 (COX-1) inhibiting drugs, namely aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs)." | 8.91 | Update on aspirin desensitization for chronic rhinosinusitis with polyps in aspirin-exacerbated respiratory disease (AERD). ( Dazy, KM; Simon, RA; Waldram, JD, 2015) |
| "Aspirin hypersensitivity associated with chronic rhinosinusitis-with or without nasal polyposis-and asthma resistant to conventional therapy defines the aspirin-exacerbated respiratory disease (AERD)." | 7.85 | Omalizumab in patient with aspirin exacerbated respiratory disease and chronic idiopathic urticaria. ( Cutrera, R; Di Marco, A; Porcaro, F, 2017) |
| "To determine any benefits or risks, expressed in early childhood, of low dose aspirin treatment in pregnancies at high risk of complications due to pre-eclampsia or intrauterine growth retardation." | 5.08 | Low dose aspirin in pregnancy and early childhood development: follow up of the collaborative low dose aspirin study in pregnancy. CLASP collaborative group. ( , 1995) |
| "Aspirin-exacerbated respiratory disease (AERD) is a clinical condition which results in adverse upper and lower respiratory symptoms, particularly rhinitis, conjunctivitis, bronchospasm, and/or laryngospasm, following exposure to cyclooxygenase-1 (COX-1) inhibiting drugs, namely aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs)." | 4.91 | Update on aspirin desensitization for chronic rhinosinusitis with polyps in aspirin-exacerbated respiratory disease (AERD). ( Dazy, KM; Simon, RA; Waldram, JD, 2015) |
| "Non-steroidal anti-inflammatory drug (NSAID)-exacerbated respiratory disease (NERD) is characterized by the triad of chronic rhinosinusitis with nasal polyp, asthma, and aspirin (ASA) or NSAID hypersensitivity." | 4.12 | Clinical characteristics and aspirin desensitization in Thai patients with a suggestive history of NSAID-exacerbated respiratory disease. ( Sompornrattanaphan, M; Tantilipikorn, P; Thongngarm, T; Wongsa, C, 2022) |
| "Aspirin-exacerbated respiratory disease (AERD) is a syndrome characterised by chronic rhinosinusitis, nasal polyps, asthma and aspirin intolerance." | 4.02 | Transcriptome Analysis Identifies Doublesex and Mab-3 Related Transcription Factor (DMRT3) in Nasal Polyp Epithelial Cells of Patients Suffering from Non-Steroidal Anti-Inflammatory Drug-Exacerbated Respiratory Disease (AERD). ( de Graaf, J; Gratziou, C; Jiménez-Chobillon, MA; Porras Gutiérrez de Velasco, R; Priyadharshini, VS; Ramírez-Jiménez, F; Teran, LM, 2021) |
| "Aspirin hypersensitivity associated with chronic rhinosinusitis-with or without nasal polyposis-and asthma resistant to conventional therapy defines the aspirin-exacerbated respiratory disease (AERD)." | 3.85 | Omalizumab in patient with aspirin exacerbated respiratory disease and chronic idiopathic urticaria. ( Cutrera, R; Di Marco, A; Porcaro, F, 2017) |
| "Aspirin hypersensitivity is a hallmark of aspirin-exacerbated respiratory disease (AERD), a clinical syndrome characterized by the severe inflammation of the respiratory tract after ingestion of cyclooxygenase-1 inhibitors." | 3.83 | Aspirin induces IL-4 production: augmented IL-4 production in aspirin-exacerbated respiratory disease. ( Chung, IY; Gi Uhm, T; Kong, SK; Park, CS; Soo Chang, H; Soo Kim, B; Sook Park, J; Woo Park, S, 2016) |
| " Prior known oral NSAIDs hypersensitivity included aspirin (5), mefenamic acid (2), diclofenac (2), Synflex (2) and ibuprofen (1)." | 3.83 | Nonsteroidal anti-inflammatory drug (NSAID) exacerbated respiratory disease phenotype: Topical NSAID and asthma control - A possible oversight link. ( Hsu, AAL; Tan, JHY, 2016) |
| "Aspirin hypersensitivity represents two distinct clinical syndromes, such as aspirin exacerbated respiratory disease (AERD) and aspirin-intolerant chronic urticaria/angioedema (AICU) which have different clinical phenotypes resulting from different genetic backgrounds in a Korean population." | 3.76 | Association of the CCR3 gene polymorphism with aspirin exacerbated respiratory disease. ( Choi, GS; Kim, SH; Lee, HN; Park, HS; Yang, EM; Ye, YM, 2010) |
| "There is a well-recognized association of aspirin sensitivity, aspirin-induced asthma, nasal polyposis or sinusitis, known as Samter's triad." | 3.76 | Aspirin sensitivity and the nose. ( Douglas, GC; Karkos, PD; Swift, AC, 2010) |
| "Aspirin treatment after desensitization (ATAD) represents an effective therapeutic option suitable for NSAID-exacerbated respiratory disease (N-ERD) patients with recalcitrant disease." | 1.72 | A retrospective study on long-term efficacy of intranasal lysine-aspirin in controlling NSAID-exacerbated respiratory disease. ( Andrews, PJ; Pendolino, AL; Scadding, GK; Scarpa, B, 2022) |
| "Aspirin was the most frequently prescribed adjoining non-anti-hypertensive drugs (39." | 1.33 | Pattern of drug utilization among hypertensives in a Nigerian teaching hospital. ( Balogun, OB; Yusuff, KB, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (6.90) | 18.7374 |
| 1990's | 1 (3.45) | 18.2507 |
| 2000's | 2 (6.90) | 29.6817 |
| 2010's | 15 (51.72) | 24.3611 |
| 2020's | 9 (31.03) | 2.80 |
| Authors | Studies |
|---|---|
| Pendolino, AL | 1 |
| Scadding, GK | 1 |
| Scarpa, B | 1 |
| Andrews, PJ | 1 |
| Schneider, S | 1 |
| Poglitsch, K | 1 |
| Morgenstern, C | 1 |
| Quint, T | 1 |
| Gangl, K | 1 |
| Sinz, C | 1 |
| Bartosik, T | 1 |
| Campion, NJ | 1 |
| Liu, DT | 1 |
| Landegger, LD | 1 |
| Tu, A | 1 |
| Stanek, V | 1 |
| Rocha-Hasler, M | 1 |
| Bangert, C | 1 |
| Eckl-Dorna, J | 1 |
| Cockcroft, DW | 1 |
| Sánchez, J | 1 |
| García, E | 1 |
| Lopez, JF | 1 |
| Calle, A | 1 |
| Buendia, JA | 1 |
| Xiao, H | 1 |
| Meng, J | 1 |
| Imam, KH | 1 |
| Woessner, KM | 1 |
| Jean, T | 1 |
| Eng, V | 1 |
| Sheikh, J | 1 |
| Kaplan, MS | 1 |
| Goldberg, B | 1 |
| Jau Yang, S | 1 |
| Samant, S | 1 |
| Wongsa, C | 1 |
| Sompornrattanaphan, M | 1 |
| Tantilipikorn, P | 1 |
| Thongngarm, T | 1 |
| Tyrak, KE | 2 |
| Pajdzik, K | 2 |
| Konduracka, E | 2 |
| Ćmiel, A | 2 |
| Jakieła, B | 2 |
| Celejewska-Wójcik, N | 1 |
| Trąd, G | 1 |
| Kot, A | 1 |
| Urbańska, A | 1 |
| Zabiegło, E | 1 |
| Kacorzyk, R | 1 |
| Kupryś-Lipińska, I | 2 |
| Oleś, K | 1 |
| Kuna, P | 2 |
| Sanak, M | 2 |
| Mastalerz, L | 2 |
| Priyadharshini, VS | 1 |
| Jiménez-Chobillon, MA | 1 |
| de Graaf, J | 1 |
| Porras Gutiérrez de Velasco, R | 1 |
| Gratziou, C | 1 |
| Ramírez-Jiménez, F | 1 |
| Teran, LM | 1 |
| Park, H | 1 |
| Choi, Y | 1 |
| Jung, CG | 1 |
| Park, HS | 3 |
| Czarnobilska, E | 1 |
| Plutecka, H | 1 |
| Koziej, M | 1 |
| Gawrońska, A | 1 |
| Losol, P | 1 |
| Kim, SH | 2 |
| Shin, YS | 1 |
| Ye, YM | 2 |
| Bobolea, I | 1 |
| Cabañas, R | 1 |
| Jurado-Palomo, J | 1 |
| Fiandor, A | 1 |
| Quirce, S | 1 |
| Klimek, L | 1 |
| Dollner, R | 1 |
| Pfaar, O | 1 |
| Mullol, J | 1 |
| Simon, RA | 1 |
| Dazy, KM | 1 |
| Waldram, JD | 1 |
| Mitsui, C | 1 |
| Kajiwara, K | 1 |
| Hayashi, H | 1 |
| Ito, J | 1 |
| Mita, H | 1 |
| Ono, E | 1 |
| Higashi, N | 1 |
| Fukutomi, Y | 1 |
| Sekiya, K | 1 |
| Tsuburai, T | 1 |
| Akiyama, K | 1 |
| Yamamoto, K | 1 |
| Taniguchi, M | 1 |
| Kong, SK | 1 |
| Soo Kim, B | 1 |
| Gi Uhm, T | 1 |
| Soo Chang, H | 1 |
| Sook Park, J | 1 |
| Woo Park, S | 1 |
| Park, CS | 1 |
| Chung, IY | 1 |
| Tan, JHY | 1 |
| Hsu, AAL | 1 |
| Porcaro, F | 1 |
| Di Marco, A | 1 |
| Cutrera, R | 1 |
| Yang, EM | 1 |
| Lee, HN | 1 |
| Choi, GS | 1 |
| Douglas, GC | 1 |
| Karkos, PD | 1 |
| Swift, AC | 1 |
| White, AA | 1 |
| Stevenson, DD | 1 |
| Weber, R | 1 |
| Trautmann, A | 1 |
| Randerath, W | 1 |
| Heppt, W | 1 |
| Hosemann, W | 1 |
| Yusuff, KB | 1 |
| Balogun, OB | 1 |
| Shaker, M | 1 |
| Lobb, A | 1 |
| Jenkins, P | 1 |
| O'Rourke, D | 1 |
| Takemoto, SK | 1 |
| Sheth, S | 1 |
| Burroughs, T | 1 |
| Dykewicz, MS | 1 |
| Vivian, AS | 1 |
| Goldberg, IB | 1 |
| Gustafson, A | 1 |
| Gustafsson, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Aspirin Desensitization on Patients With Aspirin-exacerbated Respiratory Diseases[NCT01867281] | Phase 4 | 32 participants (Actual) | Interventional | 2013-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for aspirin and Respiration Disorders
| Article | Year |
|---|---|
Nonsteroidal anti-inflammatory drug-exacerbated respiratory disease: diagnosis and current management.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Chronic Disease; Humans; Nasal Poly | 2023 |
Potential Biomarkers for NSAID-Exacerbated Respiratory Disease.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Asthma, Aspirin-Induced; Biomarke | 2017 |
Update on aspirin desensitization for chronic rhinosinusitis with polyps in aspirin-exacerbated respiratory disease (AERD).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chronic Disease; Desensitization, Immunologic; Hum | 2015 |
2 trials available for aspirin and Respiration Disorders
| Article | Year |
|---|---|
Nonsteroidal Anti-inflammatory Drug (NSAID) Tolerance After Biological Therapy in Patients With NSAID-Exacerbated Respiratory Disease: A Randomized Comparative Trial.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Biological Therapy; Humans; Inflammation; | 2023 |
Low dose aspirin in pregnancy and early childhood development: follow up of the collaborative low dose aspirin study in pregnancy. CLASP collaborative group.
Topics: Aspirin; Body Height; Body Weight; Canada; Cohort Studies; Developmental Disabilities; Double-Blind | 1995 |
24 other studies available for aspirin and Respiration Disorders
| Article | Year |
|---|---|
A retrospective study on long-term efficacy of intranasal lysine-aspirin in controlling NSAID-exacerbated respiratory disease.
Topics: Administration, Intranasal; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Lysine; Nasal | 2022 |
Dupilumab increases aspirin tolerance in NSAID-exacerbated respiratory disease.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Chronic Disease; Humans; Nasal Poly | 2023 |
NSAID-exacerbated respiratory disease, dupilumab and aspirin tolerance.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humanized; Aspirin; Humans; Respira | 2023 |
[Aspirin challenge tests in non-steroidal anti-inflammatory drugs-exacerbated respiratory disease: clinical application and current research].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Respiration Disorders; Respiratory Tract D | 2023 |
Effect of omalizumab on outcomes in patients with aspirin-exacerbated respiratory disease.
Topics: Adult; Anti-Allergic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma, Aspirin-Induc | 2019 |
Clinical characteristics and aspirin desensitization in Thai patients with a suggestive history of NSAID-exacerbated respiratory disease.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Desensitization, Immunologic; Human | 2022 |
Artificial neural network identifies nonsteroidal anti-inflammatory drugs exacerbated respiratory disease (N-ERD) cohort.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Neural Networks, Computer; Pharmaceutical | 2020 |
Transcriptome Analysis Identifies Doublesex and Mab-3 Related Transcription Factor (DMRT3) in Nasal Polyp Epithelial Cells of Patients Suffering from Non-Steroidal Anti-Inflammatory Drug-Exacerbated Respiratory Disease (AERD).
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma, Aspirin-Induced; Chronic Disease; E | 2021 |
Sputum biomarkers during aspirin desensitization in nonsteroidal anti-inflammatory drugs exacerbated respiratory disease.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Biomarkers; Carrier Proteins; | 2019 |
A genetic effect of IL-5 receptor α polymorphism in patients with aspirin-exacerbated respiratory disease.
Topics: Adult; Aspirin; Electrophoretic Mobility Shift Assay; Female; Gene Frequency; Humans; Interleukin-5 | 2013 |
Concurrent coxibs and anti-platelet therapy unmasks aspirin-exacerbated respiratory disease.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase 2 Inhibitors; Dyslipi | 2013 |
Aspirin desensitization: useful treatment for chronic rhinosinusitis with nasal polyps (CRSwNP) in aspirin-exacerbated respiratory disease (AERD)?
Topics: Aspirin; Chronic Disease; Desensitization, Immunologic; Drug Hypersensitivity; Drug Tolerance; Human | 2014 |
Platelet activation markers overexpressed specifically in patients with aspirin-exacerbated respiratory disease.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma, Aspirin-Induced; Biomarkers; | 2016 |
Aspirin induces IL-4 production: augmented IL-4 production in aspirin-exacerbated respiratory disease.
Topics: Aspirin; Cell Line; Cyclooxygenase Inhibitors; Humans; Inflammation; Interleukin-4; Respiration Diso | 2016 |
Nonsteroidal anti-inflammatory drug (NSAID) exacerbated respiratory disease phenotype: Topical NSAID and asthma control - A possible oversight link.
Topics: Administration, Topical; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma, Aspi | 2016 |
Omalizumab in patient with aspirin exacerbated respiratory disease and chronic idiopathic urticaria.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Chronic Disease; Female; Human | 2017 |
Association of the CCR3 gene polymorphism with aspirin exacerbated respiratory disease.
Topics: Adult; Aspirin; Case-Control Studies; Drug Hypersensitivity; Female; Gene Frequency; Genetic Markers | 2010 |
Aspirin sensitivity and the nose.
Topics: Aspirin; Asthma; Chronic Disease; Drug Hypersensitivity; Humans; Nasal Polyps; Respiration Disorders | 2010 |
Does suppression of IL-4 synthesis by aspirin explain the therapeutic benefit of aspirin desensitization treatment?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Desensitization, Immunologic; Drug Hypersensitivit | 2010 |
[Aspirin desensitization: therapy options in patients with aspirin-exacerbated respiratory disease].
Topics: Aspirin; Desensitization, Immunologic; Drug Hypersensitivity; Humans; Respiration Disorders | 2012 |
Pattern of drug utilization among hypertensives in a Nigerian teaching hospital.
Topics: Aspirin; Cross-Sectional Studies; Diabetes Complications; Diuretics; Drug Combinations; Drug Interac | 2005 |
An economic analysis of aspirin desensitization in aspirin-exacerbated respiratory disease.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cardiovascular Diseases; Clopidogre | 2008 |
Recognizing chronic salicylate intoxication in the elderly.
Topics: Aged; Aging; Analgesics; Aspirin; Humans; Kinetics; Respiration Disorders | 1982 |
Acute poisoning with dextropropoxyphene. Clinical symptoms and plasma concentrations.
Topics: Acidosis; Acute Disease; Adolescent; Adult; Arrhythmia, Sinus; Aspirin; Barbiturates; Dextropropoxyp | 1976 |