aspirin and Pyrosis
aspirin has been researched along with Pyrosis in 19 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "One hundred nineteen adults with active definite or classical rheumatoid arthritis were studied in a multicenter double-blind crossover study of naproxen (500 mg/day) and aspirin (3." | 9.04 | Naproxen and aspirin in rheumatoid arthritis: a multicenter double-blind crossover comparison study. ( Alexander, S; Diamond, H; Kuzell, W; Lussier, A; Odone, D; Tompkins, R, 1975) |
| "One hundred nineteen adults with active definite or classical rheumatoid arthritis were studied in a multicenter double-blind crossover study of naproxen (500 mg/day) and aspirin (3." | 5.04 | Naproxen and aspirin in rheumatoid arthritis: a multicenter double-blind crossover comparison study. ( Alexander, S; Diamond, H; Kuzell, W; Lussier, A; Odone, D; Tompkins, R, 1975) |
| "The study aimed to investigate the role of medical history (skin warts, Candida albicans, herpetic lesions, heartburn, regurgitation) and medication use (for heartburn; for regurgitation; aspirin) in the aetiology of upper aerodigestive tract (UADT) cancer." | 3.78 | Role of medical history and medication use in the aetiology of upper aerodigestive tract cancers in Europe: the ARCAGE study. ( Agudo, A; Ahrens, W; Barzan, L; Benhamou, S; Bouchardy, C; Brennan, P; Canova, C; Castellsague, X; Conway, DI; Healy, CM; Kjaerheim, K; Lagiou, A; Lagiou, P; Macfarlane, GJ; Macfarlane, TV; Marron, M; McCartan, BE; McKinney, PA; Merletti, F; Plzak, J; Pohlabeln, H; Richiardi, L; Simonato, L; Slamova, A; Sloan, P; Talamini, R; Thakker, NS; Thomson, P; Znaor, A, 2012) |
| " Fifteen healthy Japanese volunteers are dosed for 7 days in a 5-way randomly crossover trial: placebo, aspirin 100 mg, rabeprazole 10 mg, and aspirin 100 mg plus rabeprazole 10 mg either once daily or 4 times per day." | 2.75 | Esophageal mucosal injury with low-dose aspirin and its prevention by rabeprazole. ( Furuta, T; Hishida, A; Ikuma, M; Kodaira, C; Nishino, M; Sugimoto, M; Sugimura, H; Tanaka, T; Yamade, M, 2010) |
| "Aspirin is a commonly used over-the-counter (OTC) agent for the symptomatic treatment of acute pain, fever, or the common cold, but data regarding safety in this context are limited." | 2.53 | Gastrointestinal Safety of Aspirin for a High-Dose, Multiple-Day Treatment Regimen: A Meta-Analysis of Three Randomized Controlled Trials. ( Forder, S; Lanas, A; Voelker, M, 2016) |
| "Aspirin was associated with dyspepsia and/or heartburn (OR = 1." | 1.29 | Nonsteroidal antiinflammatory drugs and dyspepsia in the elderly. ( Evans, JM; Fleming, KC; Harmsen, WS; Melton, LJ; Talley, NJ; Zinsmeister, AR, 1995) |
Research
Studies (19)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (47.37) | 18.7374 |
| 1990's | 2 (10.53) | 18.2507 |
| 2000's | 3 (15.79) | 29.6817 |
| 2010's | 5 (26.32) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Forder, S | 1 |
| Voelker, M | 1 |
| Lanas, A | 1 |
| Sugimoto, M | 1 |
| Nishino, M | 1 |
| Kodaira, C | 1 |
| Yamade, M | 1 |
| Ikuma, M | 1 |
| Tanaka, T | 1 |
| Sugimura, H | 1 |
| Hishida, A | 1 |
| Furuta, T | 1 |
| Scholl, S | 1 |
| Dellon, ES | 1 |
| Shaheen, NJ | 1 |
| Macfarlane, TV | 1 |
| Macfarlane, GJ | 1 |
| Thakker, NS | 1 |
| Benhamou, S | 1 |
| Bouchardy, C | 1 |
| Ahrens, W | 1 |
| Pohlabeln, H | 1 |
| Lagiou, P | 1 |
| Lagiou, A | 1 |
| Castellsague, X | 1 |
| Agudo, A | 1 |
| Slamova, A | 1 |
| Plzak, J | 1 |
| Merletti, F | 1 |
| Richiardi, L | 1 |
| Talamini, R | 1 |
| Barzan, L | 1 |
| Kjaerheim, K | 1 |
| Canova, C | 1 |
| Simonato, L | 1 |
| Conway, DI | 1 |
| McKinney, PA | 1 |
| Thomson, P | 1 |
| Sloan, P | 1 |
| Znaor, A | 1 |
| Healy, CM | 1 |
| McCartan, BE | 1 |
| Marron, M | 1 |
| Brennan, P | 1 |
| Chitose, T | 1 |
| Hokimoto, S | 1 |
| Oshima, S | 1 |
| Nakao, K | 1 |
| Fujimoto, K | 1 |
| Miyao, Y | 1 |
| Shimomura, H | 1 |
| Tsunoda, R | 1 |
| Maruyama, H | 1 |
| Hirose, T | 1 |
| Yamamoto, K | 1 |
| Mizobe, M | 1 |
| Kaikita, K | 1 |
| Nakamura, S | 1 |
| Ogawa, H | 1 |
| Laheij, RJ | 1 |
| Van Rossum, LG | 1 |
| Jansen, JB | 1 |
| Verheugt, FW | 1 |
| Füessl, HS | 1 |
| Stiefelhagen, P | 1 |
| Rubegni, M | 1 |
| Sacchetti, G | 1 |
| Bruni, G | 1 |
| De Mauro, G | 1 |
| Provvedi, D | 1 |
| Talley, NJ | 1 |
| Evans, JM | 1 |
| Fleming, KC | 1 |
| Harmsen, WS | 1 |
| Zinsmeister, AR | 1 |
| Melton, LJ | 1 |
| Karlowicz, MG | 1 |
| White, LE | 1 |
| Diamond, H | 1 |
| Alexander, S | 1 |
| Kuzell, W | 1 |
| Lussier, A | 1 |
| Odone, D | 1 |
| Tompkins, R | 1 |
| Howden, CW | 1 |
| Sabesin, SM | 1 |
| Boyce, HW | 1 |
| King, CE | 1 |
| Mann, JA | 1 |
| Ruoff, G | 1 |
| Wall, E | 1 |
| Ramirez-Mata, M | 1 |
| Reyes, PA | 1 |
| Alarcon-Segovia, D | 1 |
| Garza, R | 1 |
| Holmes, EL | 1 |
| Hill, AG | 1 |
| Edmar, D | 1 |
Reviews
2 reviews available for aspirin and Pyrosis
| Article | Year |
|---|---|
Gastrointestinal Safety of Aspirin for a High-Dose, Multiple-Day Treatment Regimen: A Meta-Analysis of Three Randomized Controlled Trials.
Topics: Abdominal Pain; Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Female; Gastrointestinal Diseas | 2016 |
Review of flufenamic acid in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diarrhea; Dyspep | 1966 |
Trials
8 trials available for aspirin and Pyrosis
| Article | Year |
|---|---|
Esophageal mucosal injury with low-dose aspirin and its prevention by rabeprazole.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Anti-Inflammatory Agents, Non-Steroid | 2010 |
Proton-pump inhibitor therapy for acetylsalicylic acid associated upper gastrointestinal symptoms: a randomized placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; | 2003 |
A double-blind evaluation of oral indoprofen versus ASA in osteoarthritic patients: influence on haemostatic parameters and clinical effects.
Topics: Adult; Aged; Aspirin; Bleeding Time; Clinical Trials as Topic; Double-Blind Method; Female; Heartbur | 1981 |
Naproxen and aspirin in rheumatoid arthritis: a multicenter double-blind crossover comparison study.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Female; Heartbur | 1975 |
Comparative evaluation of gastrointestinal intolerance produced by plain and tri-buffered aspirin tablets.
Topics: Adult; Aspirin; Clinical Trials as Topic; Double-Blind Method; Female; Gases; Heartburn; Humans; Mal | 1988 |
Experimental observations on flufenamic, mefenamic, and meclofenamic acids. IV. Toleration by normal human subjects.
Topics: Adult; Anti-Inflammatory Agents; Aspirin; Biphenyl Compounds; Blood Coagulation; Blood Urea Nitrogen | 1966 |
Review of flufenamic acid in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diarrhea; Dyspep | 1966 |
Effects of salicylates on the gastric mucosa as revealed by roentgen examination and the gastrocamera.
Topics: Aspirin; Clinical Trials as Topic; Gastric Mucosa; Gastrointestinal Hemorrhage; Gastroscopy; Heartbu | 1971 |
Other Studies
10 other studies available for aspirin and Pyrosis
| Article | Year |
|---|---|
Treatment of GERD and proton pump inhibitor use in the elderly: practical approaches and frequently asked questions.
Topics: Adenocarcinoma; Adult; Age Distribution; Age Factors; Aged; Aged, 80 and over; Aspirin; Barrett Esop | 2011 |
Role of medical history and medication use in the aetiology of upper aerodigestive tract cancers in Europe: the ARCAGE study.
Topics: Adult; Aspirin; Candidiasis; Carcinoma, Squamous Cell; Case-Control Studies; Disease Susceptibility; | 2012 |
Clinical outcomes following coronary stenting in Japanese patients treated with and without proton pump inhibitor.
Topics: Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Asian People; Aspirin; Clopidogrel; Coronar | 2012 |
[Heartburn without esophagitis. Symptoms more important than the finding?].
Topics: Androstadienes; Antacids; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ul | 2003 |
[Gastroenterology in family practice. Updates for your "stomach patient"].
Topics: Anti-Ulcer Agents; Aspirin; Clopidogrel; Dyspepsia; Esophagitis, Peptic; Family Practice; Heartburn; | 2006 |
Nonsteroidal antiinflammatory drugs and dyspepsia in the elderly.
Topics: Age Distribution; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dyspepsia; Female; Heartbu | 1995 |
Severe intracranial hemorrhage in a term neonate associated with maternal acetylsalicylic acid ingestion.
Topics: Alcohol Drinking; Aspirin; Cerebral Hemorrhage; Female; Heartburn; Humans; Infant, Newborn; Male; Ma | 1993 |
Treatment of common minor ailments.
Topics: Acetaminophen; Antacids; Antiemetics; Aspirin; Dyspepsia; Female; Heartburn; Histamine H1 Antagonist | 1986 |
Esophageal motility in systemic lupus erythematosus.
Topics: Adolescent; Adult; Aged; Aspirin; Azathioprine; Chloroquine; Deglutition Disorders; Dilatation; Drug | 1974 |
Gastrointestinal disturbances with aspirin.
Topics: Animals; Aspirin; Dogs; Gastrointestinal Hemorrhage; Heartburn; Humans; Tablets, Enteric-Coated | 1965 |