Page last updated: 2024-10-23

aspirin and Purpura, Thrombotic Thrombocytopenic

aspirin has been researched along with Purpura, Thrombotic Thrombocytopenic in 92 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Purpura, Thrombotic Thrombocytopenic: An acquired, congenital, or familial disorder caused by PLATELET AGGREGATION with THROMBOSIS in terminal arterioles and capillaries. Clinical features include THROMBOCYTOPENIA; HEMOLYTIC ANEMIA; AZOTEMIA; FEVER; and thrombotic microangiopathy. The classical form also includes neurological symptoms and end-organ damage, such as RENAL FAILURE. Mutations in the ADAMTS13 PROTEIN gene have been identified in familial cases.

Research Excerpts

ExcerptRelevanceReference
"Thrombotic thrombocytopenic purpura is an uncommon disease with a high mortality rate even with current treatment."2.67Comparison of plasma exchange with plasma infusion in the treatment of thrombotic thrombocytopenic purpura. Canadian Apheresis Study Group. ( Blanchette, VS; Buskard, NA; Kelton, JG; Nair, RC; Rock, GA; Shumak, KH; Spasoff, RA, 1991)
"Prednisone alone was judged to be effective in 30 patients with mild TTP-HUS (two relapses and two deaths)."2.67Improved survival in thrombotic thrombocytopenic purpura-hemolytic uremic syndrome. Clinical experience in 108 patients. ( Bell, WR; Braine, HG; Kickler, TS; Ness, PM, 1991)
" Clinicians who decide to manage complicated or potentially complicated patients with chronic administration of aspirin must continue to study these mothers, fetuses, and neonates intensively and to document their results."2.38Low-dose aspirin to improve perinatal outcome. ( Barton, JR; Sibai, BM, 1991)
"The use of prostacyclin infusion in thrombotic thrombocytopenic purpura is consistent with the hypothesis that patients may lack a plasma factor stimulating prostacyclin production."2.38Intravenous prostacyclin in thrombotic thrombocytopenic purpura: case report and review of the literature. ( Bertrand, JC; Comtet, C; Decousus, H; Page, Y; Tardy, B; Tardy-Poncet, B; Zeni, F, 1991)
"Pregnancy is an initiating event for acute thrombotic thrombocytopaenic purpura (TTP)."1.33Successful management of pregnancy in women with a history of thrombotic thrombocytopaenic purpura. ( Cohen, H; Lee, R; Machin, S; Mackie, I; Scully, M; Starke, R, 2006)
"Some patients with thrombotic thrombocytopenic purpura (TTP) remain plasma-exchange-dependent for prolonged periods of time."1.30Splenectomy during partial remission in thrombotic thrombocytopenic purpura with prolonged plasma exchange dependency. ( Bruce, D; Larratt, LM; Mant, MJ; Ritchie, C; Turner, AR, 1999)
"We examined 159 patients with thrombotic thrombocytopenic purpura and hemolytic uremic syndrome in Japan."1.30Outcome of thrombotic thrombocytopenic purpura and hemolytic uremic syndrome in Japan. ( Ihara, T; Kakisita, E; Minami, N; Mori, Y; Omine, M; Shiku, H; Tamaki, S; Wada, H, 1999)
"Thirteen patients with thrombotic thrombocytopenic purpura were treated at our facility between 1985 and 1991."1.28Thrombotic thrombocytopenic purpura: a multimodality model of treatment including plasma exchange, i.v. immunoglobulin, prednisone, antiplatelet agents, vincristine and splenectomy. ( Belia, M; Bouronikou, H; Dervenoulas, J; Economopoulos, T; Karakassis, D; Papageorgiou, E; Pappa, V; Raptis, S; Stavrou, A; Stylogiannis, S, 1992)
"Erythromelalgia is characterized by paroxysmal burning pain and redness of the distal extremities; primary and secondary forms exist."1.28Erythromelalgia in a patient with thrombotic thrombocytopenic purpura. ( Blickstein, D; Krause, I; Yosipovitch, G, 1992)
"Thrombotic thrombocytopenic purpura is a severe multisystemic disorder of unknown origin."1.28Successful pregnancies of two patients with relapsing thrombotic thrombocytopenic purpura. ( Eldor, A; Ezra, Y; Mordel, N; Sadovsky, E; Schenker, JG, 1989)
"Eight patients with thrombotic thrombocytopenic purpura (TTP) originating within a 25-mile radius had their conditions diagnosed in a three-year period at a community teaching hospital in southeastern New England."1.27Thrombotic thrombocytopenic purpura in southeastern New England. ( Clark, DD; Crowley, JP; O'Shea, PA; Zaroulis, CG, 1983)
"We report a case of thrombotic thrombocytopenic purpura which responded spectacularly to therapy consisting of corticosteroids, prostacyclin, high doses of platelet anti-aggregants and repeated plasma exchange."1.27[Aggressive therapy in a case of Moschowitz syndrome]. ( Beris, P; Miescher, PA; Parmeggiani, L; Trono, D, 1984)
"Twenty-one episodes of thrombotic thrombocytopenic purpura (TTP) were treated with plasmapheresis."1.27Thrombotic thrombocytopenic purpura: treatment with plasmapheresis. ( Blitzer, JB; Goldberg, J; Gottlieb, AJ; Granfortuna, JM; Lamberson, H; Landaw, SA; Scalzo, AJ; Smith, JR; Theodorakis, ME; Zamkoff, KW, 1987)
"20 patients with thrombotic thrombocytopenic purpura (TTP) admitted to the Mt."1.26Thrombotic thrombocytopenic purpura: a ten-year experience. ( Cuttner, J, 1980)
"2 cases of acute idiopathic thrombotic thrombocytopenic purpura are reported."1.26Normal prostacyclinlike activity and response to plasma exchange in thrombotic thrombocytopenic purpura: report of 2 cases. ( Manotti, C; Megha, A; Pini, M; Poli, T; Potì, R, 1982)
"Seven of eight patients with thrombotic thrombocytopenic purpura who were treated with both exchange plasmapheresis and antiplatelet agents (aspirin and dipyridamole) achieved complete remission."1.26Thrombotic thrombocytopenic purpura: combined treatment with plasmapheresis and antiplatelet agents. ( Ball, ED; Myers, TJ; Tremont, SJ; Wakem, CJ, 1980)
"Report on 5 patients with thrombotic thrombocytopenic purpura."1.26[Thrombotic thrombocytopenic purpura: report on 5 cases and current therapy concepts]. ( Cornu, P; Gratwohl, A; Richner, J; Speck, B, 1981)
"We conclude that prolonged coma without evidence of major central nervous system structural lesions in TTP should be treated vigorously and continuously with plasma exchange."1.26Thrombotic thrombocytopenic purpura: prolonged coma with recovery of neurologic function with intensive plasma exchange. ( Frankel, AE; Rubenstein, MD; Wall, RT, 1981)
"Two patients with thrombotic thrombocytopenic purpura were seen."1.26Platelet-latelet-. ( Bozdech, MJ; Crowell, EB; Eckel, RH; Waterhouse, BE, 1977)
"When thrombotic thrombocytopenic purpura (TTP) occurs in pregnancy, survival of either the mother or fetus is exceedingly rare."1.26Survival following thrombotic thrombocytopenic purpura in pregnancy. ( Burkhardt, JH; Fitzgibbons, JF; Goodnight, SH; Kirk, PE, 1977)
"A case of thrombotic thrombocytopenic purpura in which sustained remission followed splenectomy is described."1.26Thrombotic thrombocytopenic purpura--remission following splenectomy. Report of a case and review of the literature. ( Brine, JA; Jackson, JM; Reynolds, PM; Vivian, AB, 1976)

Research

Studies (92)

TimeframeStudies, this research(%)All Research%
pre-199061 (66.30)18.7374
1990's19 (20.65)18.2507
2000's9 (9.78)29.6817
2010's1 (1.09)24.3611
2020's2 (2.17)2.80

Authors

AuthorsStudies
Shao, B2
Hoover, C1
Shi, H1
Kondo, Y1
Lee, RH1
Chen, J1
Shan, X1
Song, J1
McDaniel, JM1
Zhou, M1
McGee, S1
Vanhoorelbeke, K1
Bergmeier, W1
López, JA1
George, JN2
Xia, L2
Nusrat, S1
Yamashita, E1
Okada, H1
Yorioka, H1
Fujita, S1
Nishi, K1
Komiyama, Y1
Kanzaki, H1
Liatsos, G1
George, L1
Elefsiniotis, I1
Ioannis, E1
Todorova, R1
Radostina, T1
Moulakakis, A1
Antonios, M1
Patel, TN1
Kreindel, M1
Lincoff, AM1
Matzdorff, AC1
Scully, M1
Starke, R1
Lee, R1
Mackie, I1
Machin, S1
Cohen, H1
Takahashi, R1
Budd, GT1
Bukowski, RM2
Lucas, FV1
Cato, AE1
Cocchetto, DM1
Cuttner, J1
Hewlett, JS1
Reimer, RR1
Groppe, CW1
Weick, JK1
Livingston, RB1
Pini, M2
Potí, R2
Dettori, AG1
Villegas, A1
Alvarez-Sala, JL1
Espinós, D1
Crowley, JP1
Zaroulis, CG1
O'Shea, PA1
Clark, DD1
Trono, D1
Beris, P1
Parmeggiani, L1
Miescher, PA1
Vandekerckhove, F1
Noens, L1
Colardyn, F1
Thiery, M1
Delbarge, W1
Stoffner, D1
Banthien, FC1
Habersetzer, R1
Samtleben, W1
Clemm, C1
Unterburger, P1
Zähringer, J1
Gurland, HJ1
Aul, C1
Scharf, RE1
Königshausen, T1
Küppers, H1
Grabensee, B1
Ortiz Monzó, F1
Sancho García, RA1
Filgueira Rubio, JS1
Jiménez Fernández, J1
Fernández Basave, E1
Chiba, J1
Matsunaga, K1
Ishigatsubo, Y1
Kodama, F1
Itoh, A1
Fukushima, K1
Marmont, AM1
Damasio, E2
Rossi, E1
Spriano, M1
Manotti, C1
Megha, A1
Poli, T1
Thysell, H1
Oxelius, VA1
Norlin, M1
Phillips, BA1
Riddell, DG1
Rogers, PC1
Carter, JE1
Willoughby, ML1
Rosove, MH1
Ho, WG1
Goldfinger, D1
Myers, TJ2
Wakem, CJ1
Ball, ED1
Tremont, SJ1
Pisciotta, AV1
Deuel, T1
Gardner, F1
Peck, WA1
Richner, J1
Gratwohl, A1
Cornu, P1
Speck, B1
Frankel, AE1
Rubenstein, MD1
Wall, RT1
Sims, PJ1
Boswell, EB1
Nagata, S1
Kosaka, H1
Sadamoto, H1
Rothberg, H1
Pachter, I1
Kosmin, M1
Stevens, DB1
Patton, JF1
Manning, KR1
Case, D1
Owen, J1
Heigl, F1
Heigl, B1
Kampfhammer, HP1
Hiller, E1
Steinbeck, G1
Ezra, Y2
Rose, M1
Eldor, A2
Alqadah, F1
McCullough, PA1
Marks, KR1
Mant, MJ1
Turner, AR1
Bruce, D1
Ritchie, C1
Larratt, LM1
Mori, Y1
Wada, H1
Tamaki, S1
Minami, N1
Shiku, H1
Ihara, T1
Omine, M1
Kakisita, E1
McDonald, HR1
Bruni, R1
Giannini, G1
Lercari, G1
Bo, A1
Florio, G1
De Luigi, MC1
Marmont, A1
Gobbi, A1
Valbonesi, M2
Chamouni, P1
Lenain, P1
Buchonnet, G1
Merle, V1
Bourgain, C1
Boyer, A1
Girault, C1
Czernichow, P1
Baron, BW1
Martin, MS1
Sucharetza, BS1
Jeon, H1
Baron, JM1
Proia, A1
Paesano, R1
Torcia, F1
Annino, L1
Capria, S1
Ferrari, A1
Ferrazza, G1
Pacifici, E1
Pantalissi, A1
Meloni, G1
de Jong, MC1
Monnens, LA1
Gorin, NC1
Fraitag, B1
Feldman, A1
Vallot, T1
Couturier, JY1
Najman, A1
Duhamel, G1
Byrnes, JJ1
Lian, EC1
Gundlach, WJ1
Tarnasky, R1
Amorosi, EL1
Karpatkin, S1
Eckel, RH1
Crowell, EB1
Waterhouse, BE1
Bozdech, MJ1
Fitzgibbons, JF1
Goodnight, SH1
Burkhardt, JH1
Kirk, PE1
Sumalnop, V1
Birgens, H1
Ernst, P2
Hansen, MS1
Stern, R1
Cornell, CJ1
Beck, R1
Smith, RE1
Farina, ML1
Langer, M1
Donati, MB1
de Gaetano, G1
Reynolds, PM1
Jackson, JM1
Brine, JA1
Vivian, AB1
Dervenoulas, J1
Karakassis, D1
Belia, M1
Pappa, V1
Economopoulos, T1
Papageorgiou, E1
Stavrou, A1
Bouronikou, H1
Stylogiannis, S1
Raptis, S1
Revell, P1
Slater, NG1
Naruse, T1
Yosipovitch, G1
Krause, I1
Blickstein, D1
Rozdzinski, E1
Hertenstein, B1
Schmeiser, T1
Seifried, E1
Kurrle, E1
Heimpel, H1
Barton, JR1
Sibai, BM1
Tardy, B1
Page, Y1
Comtet, C1
Tardy-Poncet, B1
Zeni, F1
Decousus, H1
Bertrand, JC1
Rock, GA1
Shumak, KH1
Buskard, NA1
Blanchette, VS1
Kelton, JG1
Nair, RC1
Spasoff, RA1
Bell, WR1
Braine, HG1
Ness, PM1
Kickler, TS1
Vlot, AJ1
Hené, RJ1
Sixma, JJ1
McCarthy, L1
Kotylo, P1
Lister, K2
Bagi, P1
Birgens, HS1
del Zoppo, GJ1
Mordel, N1
Sadovsky, E1
Schenker, JG1
McCormick, KC1
Valente, U1
Pellicci, R1
Piri, C1
Ferrari, M1
Frisoni, R1
Zia, S1
Quaratino, S1
Fella, M1
McCarthy, LJ1
Sierakowski, S1
Blitzer, JB1
Granfortuna, JM1
Gottlieb, AJ1
Smith, JR1
Theodorakis, ME1
Zamkoff, KW1
Landaw, SA1
Goldberg, J1
Scalzo, AJ1
Lamberson, H1
Kulkarni, GA1
Pellegrini, JR1
Nathanson, L1
Ambrose, A1
Welham, RT1
Cefalo, RC1
Jobin, F1
DeLage, JM1
Rossi, EC1
Redondo, D1
Borges, WH1
Faguet, GB1
King, MB1
Amir, J1
Krauss, S1
Jaffe, EA1
Nachman, RL1
Merskey, C1
Goldenfarb, PB1
Finch, SC1
Aster, RH1
Berberich, FR1
Cuene, SA1
Chard, RL1
Hartmann, JR1
Giromini, M1
Bouvier, CA1
Dami, R1
Denizot, M1
Jeannet, M1
Zacharski, LR1
Walworth, C1
McIntyre, OR1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective Multicenter Clinical Study of Aspirin for Prophylaxis in Patients With Hereditary or Acquired Thrombotic Thrombocytopenic Purpura[NCT05568147]Phase 2/Phase 3100 participants (Anticipated)Interventional2022-10-01Not yet recruiting
PILOT STUDY in the Use of Therapeutic Plasma Exchange in Adult Patients With Severe Sepsis[NCT04057872]Phase 154 participants (Anticipated)Interventional2020-10-21Recruiting
A Retrospective, Observational Study on the Response to Caplacizumab Treatment in aTTP Patients: the Italian Experience (ROSCAPLI)[NCT05262881]50 participants (Anticipated)Observational2022-03-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

16 reviews available for aspirin and Purpura, Thrombotic Thrombocytopenic

ArticleYear
[Drug-induced thrombotic thrombocytopenic purpura].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Oct-28, Volume: 65 Suppl 8

    Topics: Antirheumatic Agents; Aspirin; Cyclosporine; Diagnosis, Differential; Humans; Immunosuppressive Agen

2007
Therapy of thrombotic thrombocytopenic purpura: an overview.
    Seminars in thrombosis and hemostasis, 1981,Winter, Volume: 7, Issue:1

    Topics: Adrenal Cortex Hormones; Aspirin; Blood Transfusion; Dextrans; Dipyridamole; Humans; Immunosuppressi

1981
[Thrombotic thrombopenic purpura. Description of 2 cases and review of the literature].
    Recenti progressi in medicina, 1982, Volume: 73, Issue:4

    Topics: Adult; Aspirin; Autoimmune Diseases; Bacterial Infections; Blood Transfusion; Dextrans; Dipyridamole

1982
[Treatment of the hemolytic-uremic syndrome and thrombotic thrombopenic purpura].
    Sangre, 1983, Volume: 28, Issue:5

    Topics: Anticoagulants; Aspirin; Hemolytic-Uremic Syndrome; Humans; Plasmapheresis; Purpura, Thrombotic Thro

1983
[Congenital and acquired thrombocyte function disorders].
    Kinderarztliche Praxis, 1980, Volume: 48, Issue:7

    Topics: Aspirin; Blood Platelet Disorders; Dipyridamole; Fibrin Fibrinogen Degradation Products; Heart Defec

1980
Therapy and prevention of thrombotic thrombocytopenic purpura during pregnancy: a clinical study of 16 pregnancies.
    American journal of hematology, 1996, Volume: 51, Issue:1

    Topics: Adrenal Cortex Hormones; Adult; Aspirin; Combined Modality Therapy; Diagnostic Errors; Dipyridamole;

1996
Aspirin and ticlopidine after routine coronary stenting: the gold standard as of 1999.
    Journal of thrombosis and thrombolysis, 1999, Volume: 7, Issue:3

    Topics: Anemia, Aplastic; Angioplasty, Balloon, Coronary; Aspirin; Clinical Trials as Topic; Clopidogrel; Co

1999
Four patients with both thrombotic thrombocytopenic purpura and autoimmune thrombocytopenic purpura: the concept of a mixed immune thrombocytopenia syndrome and indications for plasma exchange.
    Journal of clinical apheresis, 2001, Volume: 16, Issue:4

    Topics: Adult; Arthritis, Rheumatoid; Aspirin; Autoimmune Diseases; Blood Platelets; Combined Modality Thera

2001
Thrombotic thrombocytopenic purpura and pregnancy: a case report and a review of the literature.
    Annals of hematology, 2002, Volume: 81, Issue:4

    Topics: Adult; Aspirin; Disease Management; Female; Heparin; Humans; Practice Guidelines as Topic; Pregnancy

2002
Recent therapeutic advances in thrombotic thrombocytopenic purpura.
    Seminars in thrombosis and hemostasis, 1979,Winter, Volume: 5, Issue:3

    Topics: Adolescent; Adult; Aspirin; Blood Transfusion; Dextrans; Dipyridamole; Exchange Transfusion, Whole B

1979
Low-dose aspirin to improve perinatal outcome.
    Clinical obstetrics and gynecology, 1991, Volume: 34, Issue:2

    Topics: Antibodies; Aspirin; Blood Coagulation Factors; Cardiolipins; Female; Fetal Growth Retardation; Fetu

1991
Intravenous prostacyclin in thrombotic thrombocytopenic purpura: case report and review of the literature.
    Journal of internal medicine, 1991, Volume: 230, Issue:3

    Topics: Adult; Aspirin; Blood Transfusion; Combined Modality Therapy; Dipyridamole; Epoprostenol; Humans; In

1991
Antiplatelet therapy in thrombotic thrombocytopenic purpura.
    Seminars in hematology, 1987, Volume: 24, Issue:2

    Topics: Aspirin; Blood Platelets; Dextrans; Dipyridamole; Epoprostenol; Humans; Microcirculation; Platelet A

1987
Thrombotic thrombocytopenic purpura.
    The Journal of the American Osteopathic Association, 1989, Volume: 89, Issue:2

    Topics: Adult; Aspirin; Combined Modality Therapy; Dipyridamole; Humans; Male; Plasma Exchange; Plasmapheres

1989
[New theories on the pathogenesis and methods of treating thrombotic thrombocytopenic purpura (Moschkowitz disease)].
    Polskie Archiwum Medycyny Wewnetrznej, 1986, Volume: 75, Issue:1

    Topics: Adolescent; Adult; Aspirin; Blood Coagulation Disorders; Child; Dipyridamole; Epoprostenol; Female;

1986
Thrombotic thrombocytopenic purpura.
    American family physician, 1985, Volume: 31, Issue:2

    Topics: Adrenal Cortex Hormones; Adult; Aspirin; Diagnosis, Differential; Dipyridamole; Female; Humans; Plas

1985

Trials

3 trials available for aspirin and Purpura, Thrombotic Thrombocytopenic

ArticleYear
Cascade filtration for TTP: an effective alternative to plasma exchange with cryodepleted plasma.
    Transfusion science, 1999, Volume: 21, Issue:3

    Topics: Adult; Antineoplastic Agents, Phytogenic; Aspirin; Blood Component Removal; Dipyridamole; Female; He

1999
Comparison of plasma exchange with plasma infusion in the treatment of thrombotic thrombocytopenic purpura. Canadian Apheresis Study Group.
    The New England journal of medicine, 1991, Aug-08, Volume: 325, Issue:6

    Topics: Adult; Aspirin; Blood Transfusion; Dipyridamole; Female; Humans; Male; Monitoring, Physiologic; Plas

1991
Improved survival in thrombotic thrombocytopenic purpura-hemolytic uremic syndrome. Clinical experience in 108 patients.
    The New England journal of medicine, 1991, Aug-08, Volume: 325, Issue:6

    Topics: Adolescent; Adult; Aged; Aspirin; Blood Transfusion; Dipyridamole; Female; Hemolytic-Uremic Syndrome

1991

Other Studies

73 other studies available for aspirin and Purpura, Thrombotic Thrombocytopenic

ArticleYear
Deletion of platelet CLEC-2 decreases GPIbα-mediated integrin αIIbβ3 activation and decreases thrombosis in TTP.
    Blood, 2022, 04-21, Volume: 139, Issue:16

    Topics: Aspirin; Blood Platelets; Humans; Hypertension, Pulmonary; Lectins, C-Type; Platelet Activation; Pla

2022
Aspirin prophylaxis for hereditary and acquired thrombotic thrombocytopenic purpura?
    American journal of hematology, 2022, Volume: 97, Issue:8

    Topics: ADAMTS13 Protein; Analgesics; Aspirin; Humans; Plasma Exchange; Purpura, Thrombotic Thrombocytopenic

2022
Successful management of pregnancy-associated thrombotic thrombocytopenic purpura by monitoring ADAMTS13 activity.
    The journal of obstetrics and gynaecology research, 2012, Volume: 38, Issue:3

    Topics: ADAM Proteins; ADAMTS13 Protein; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biomarkers

2012
Severe thrombotic thrombocytopenic purpura (TTP) induced or exacerbated by the immunostimulatory herb Echinacea.
    American journal of hematology, 2006, Volume: 81, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Aspirin; Blood Co

2006
Use of ticlopidine and cilostazol after intracoronary drug-eluting stent placement in a patient with previous clopidogrel-induced thrombotic thrombocytopenic purpura: a case report.
    The Journal of invasive cardiology, 2006, Volume: 18, Issue:7

    Topics: ADAM Proteins; ADAMTS1 Protein; Aged; Apoptosis; Aspirin; Autoantibodies; Cilostazol; Clopidogrel; C

2006
Thrombotic thrombocytopenic purpura.
    The New England journal of medicine, 2006, Aug-10, Volume: 355, Issue:6

    Topics: Aspirin; Combined Modality Therapy; Humans; Plasma Exchange; Platelet Aggregation Inhibitors; Purpur

2006
Successful management of pregnancy in women with a history of thrombotic thrombocytopaenic purpura.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2006, Volume: 17, Issue:6

    Topics: ADAM Proteins; ADAMTS13 Protein; Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Deriv

2006
Prostacyclin therapy of thrombotic thrombocytopenic purpura.
    Lancet (London, England), 1980, Oct-25, Volume: 2, Issue:8200

    Topics: Aspirin; Dipyridamole; Drug Therapy, Combination; Epoprostenol; Female; Humans; Middle Aged; Prostag

1980
Thrombotic thrombocytopenic purpura: a ten-year experience.
    Blood, 1980, Volume: 56, Issue:2

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aspirin; Dextrans; Dipyridamole; Female; Heparin;

1980
Thrombotic thrombocytopenic purpura in southeastern New England.
    Archives of internal medicine, 1983, Volume: 143, Issue:5

    Topics: Adolescent; Adult; Aspirin; Dipyridamole; Disease Outbreaks; Female; Humans; Male; Methylprednisolon

1983
[Aggressive therapy in a case of Moschowitz syndrome].
    Nouvelle revue francaise d'hematologie, 1984, Volume: 26, Issue:6

    Topics: Adrenal Cortex Hormones; Aspirin; Dipyridamole; Drug Therapy, Combination; Epoprostenol; Female; Hum

1984
Thrombotic thrombocytopenic purpura mimicking toxemia of pregnancy.
    American journal of obstetrics and gynecology, 1984, Oct-01, Volume: 150, Issue:3

    Topics: Adrenal Cortex Hormones; Adult; Aspirin; Diagnosis, Differential; Dipyridamole; Female; Fetal Death;

1984
Plasma exchange and concomitant therapy in TTP.
    The International journal of artificial organs, 1984, Volume: 7, Issue:4

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aspirin; Dipyridamole; Female; Fibrin Fibrinogen Degrada

1984
[Differential therapy of thrombotic-thrombopenic purpura. Administration of fresh plasma versus plasma separation].
    Deutsche medizinische Wochenschrift (1946), 1984, Dec-14, Volume: 109, Issue:50

    Topics: Acute Kidney Injury; Adult; Aspirin; Blood Platelets; Blood Transfusion; Dipyridamole; Erythrocytes;

1984
[Platelet anti-aggregants as a treatment for thrombotic thrombocytopenic purpura. Apropos of a case].
    Revista clinica espanola, 1983, May-31, Volume: 169, Issue:4

    Topics: Aspirin; Dipyridamole; Humans; Male; Middle Aged; Platelet Aggregation; Purpura, Thrombotic Thromboc

1983
[A case of thrombotic thrombocytopenic purpura (TTP), clinically diagnosed and cured by dipyridamole, urokinase and aspirin].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1982, Volume: 23, Issue:5

    Topics: Adult; Aspirin; Dipyridamole; Endopeptidases; Female; Humans; Purpura, Thrombotic Thrombocytopenic;

1982
Thrombotic thrombocytopenic purpura successfully treated with a combination of dipyridamole and aspirin.
    Haematologica, 1980, Volume: 65, Issue:2

    Topics: Adult; Aspirin; Dipyridamole; Humans; Male; Purpura, Thrombotic Thrombocytopenic

1980
Normal prostacyclinlike activity and response to plasma exchange in thrombotic thrombocytopenic purpura: report of 2 cases.
    Acta haematologica, 1982, Volume: 67, Issue:3

    Topics: Adult; Aspirin; Epoprostenol; Female; Humans; Middle Aged; Plasma Exchange; Platelet Aggregation; Pr

1982
Successful treatment of hemolytic uremic syndrome and thrombotic thrombocytopenic purpura with fresh frozen plasma and plasma exchange.
    Acta medica Scandinavica, 1982, Volume: 212, Issue:5

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aspirin; Child; Child, Preschool; Dipyridamole; Female;

1982
A case of probable thrombotic thrombocytopenic purpura responding to exchange transfusion.
    The American journal of pediatric hematology/oncology, 1982,Winter, Volume: 4, Issue:4

    Topics: Aspirin; Diagnosis, Differential; Exchange Transfusion, Whole Blood; Female; Hemolytic-Uremic Syndro

1982
Ineffectiveness of aspirin and dipyridamole in the treatment of thrombotic thrombocytopenic purpura.
    Annals of internal medicine, 1982, Volume: 96, Issue:1

    Topics: Adolescent; Adult; Aged; Aspirin; Dipyridamole; Epistaxis; Epoprostenol; Female; Gastrointestinal He

1982
Thrombotic thrombocytopenic purpura: combined treatment with plasmapheresis and antiplatelet agents.
    Annals of internal medicine, 1980, Volume: 92, Issue:2 Pt 1

    Topics: Adult; Aged; Aspirin; Dipyridamole; Female; Humans; Male; Middle Aged; Plasmapheresis; Prednisone; P

1980
Thrombotic thrombocytopenic purpura.
    Annals of internal medicine, 1980, Volume: 92, Issue:2 Pt 1

    Topics: Adrenal Cortex Hormones; Aspirin; Dipyridamole; Exchange Transfusion, Whole Blood; Humans; Plasmaphe

1980
Thrombotic thrombocytopenic purpura.
    Archives of internal medicine, 1980, Volume: 140, Issue:1

    Topics: Adult; Aspirin; Blood Transfusion; Dipyridamole; Female; Humans; Prednisone; Purpura, Thrombotic Thr

1980
[Thrombotic thrombocytopenic purpura: report on 5 cases and current therapy concepts].
    Schweizerische medizinische Wochenschrift, 1981, Mar-14, Volume: 111, Issue:11

    Topics: Adult; Aspirin; Dipyridamole; Evaluation Studies as Topic; Exchange Transfusion, Whole Blood; Female

1981
Treatment of thrombotic thrombocytopenic purpura with combined exchange plasmapheresis and anti-platelet agents.
    Seminars in thrombosis and hemostasis, 1981,Winter, Volume: 7, Issue:1

    Topics: Adult; Aged; Aspirin; Dipyridamole; Dose-Response Relationship, Drug; Female; Humans; Male; Middle A

1981
Thrombotic thrombocytopenic purpura: prolonged coma with recovery of neurologic function with intensive plasma exchange.
    American journal of hematology, 1981, Volume: 10, Issue:4

    Topics: Aspirin; Coma; Dipyridamole; Female; Humans; Middle Aged; Plasma Exchange; Platelet Count; Prednisol

1981
Elevated platelet-bound IgG associated with an episode of thrombotic thrombocytopenic purpura.
    Blood, 1981, Volume: 58, Issue:4

    Topics: Aspirin; Blood Platelets; Dipyridamole; Female; Humans; Immunoglobulin G; Middle Aged; Plasma Exchan

1981
[Thrombotic thrombocytopenic purpura--successful treatment by warfarin and antiplatelet drugs (author's transl)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1981, Volume: 22, Issue:5

    Topics: Adult; Aspirin; Dipyridamole; Drug Therapy, Combination; Female; Humans; Prednisolone; Purpura, Thro

1981
Aspirin dipyridamole, and thrombotic thrombocytopenic purpura.
    Annals of internal medicine, 1982, Volume: 96, Issue:5

    Topics: Aspirin; Dipyridamole; Humans; Platelet Aggregation; Purpura, Thrombotic Thrombocytopenic

1982
Thrombotic thrombocytopenic purpura: recovery after plasmapheresis, corticosteroids, splenectomy, and antiplatelet agents.
    American journal of hematology, 1982, Volume: 12, Issue:3

    Topics: Aged; Aspirin; Blood Platelets; Female; Humans; Methylprednisolone; Plasmapheresis; Purpura, Thrombo

1982
Serum lactate dehydrogenase and platelet count predict survival in thrombotic thrombocytopenic purpura.
    American journal of hematology, 1994, Volume: 47, Issue:2

    Topics: Adult; Aged; Aspirin; Female; Humans; Immunoglobulins, Intravenous; L-Lactate Dehydrogenase; Male; M

1994
[Chronic recurrent thrombotic thrombocytopenic purpura (Moschcowitz disease). An unusual long-term course in a 43-year-old patient].
    Der Internist, 1993, Volume: 34, Issue:10

    Topics: Adult; Aspirin; Biopsy; Cerebral Angiography; Cerebral Infarction; Combined Modality Therapy; Female

1993
Thrombotic thrombocytopenic purpura in pregnancy.
    Postgraduate medical journal, 1996, Volume: 72, Issue:854

    Topics: Aspirin; Female; Humans; Plasma Exchange; Pregnancy; Pregnancy Complications, Hematologic; Purpura,

1996
Splenectomy during partial remission in thrombotic thrombocytopenic purpura with prolonged plasma exchange dependency.
    American journal of hematology, 1999, Volume: 62, Issue:1

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents; Aspirin; Combined Modality Therapy; Erythrocyte Tran

1999
Outcome of thrombotic thrombocytopenic purpura and hemolytic uremic syndrome in Japan.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 1999, Volume: 5, Issue:2

    Topics: Adolescent; Adult; Aged; Aspirin; Bacterial Toxins; Child; Child, Preschool; Clinical Trials as Topi

1999
Diagnostic and therapeutic challenges.
    Retina (Philadelphia, Pa.), 2000, Volume: 20, Issue:2

    Topics: Adult; Aspirin; Female; Fluorescein Angiography; Humans; Plasmapheresis; Prednisone; Purpura, Thromb

2000
Difficulties in the management of an incomplete form of refractory thrombotic thrombocytopenic purpura, the usefulness of vincristine.
    Transfusion science, 2000, Volume: 23, Issue:2

    Topics: Adrenal Cortex Hormones; Adult; Antigens, Human Platelet; Antimetabolites; Aspirin; Autoantibodies;

2000
Recurrent haemolytic uraemic syndrome.
    Padiatrie und Padologie, 1976, Volume: 11, Issue:3

    Topics: Adenoviridae; Antibodies, Viral; Anticoagulants; Aspirin; Child, Preschool; Dicumarol; Diphtheria To

1976
[Moschowitz's disease: efficacy of anti-platelet aggregation agents].
    La Nouvelle presse medicale, 1977, Dec-10, Volume: 6, Issue:42

    Topics: Adrenocorticotropic Hormone; Anemia, Hemolytic; Aspirin; Cosyntropin; Dipyridamole; Drug Evaluation;

1977
Thrombotic thrombocytopenic purpura. Remission following treatment with aspirin and dipyridamole.
    Minnesota medicine, 1977, Volume: 60, Issue:1

    Topics: Adolescent; Aspirin; Dipyridamole; Drug Therapy, Combination; Humans; Male; Purpura, Thrombotic Thro

1977
Antiplatelet treatment of thrombotic thrombocytopenic purpura.
    Annals of internal medicine, 1977, Volume: 86, Issue:1

    Topics: Adolescent; Adult; Aged; Aspirin; Blood Platelets; Cyproheptadine; Dextrans; Dipyridamole; Female; H

1977
Therapy for thrombotic thrombocytopenic purpura.
    Annals of internal medicine, 1977, Volume: 86, Issue:5

    Topics: Aspirin; Dextrans; Dipyridamole; Female; Humans; Hydrocortisone; Male; Methylprednisolone; Middle Ag

1977
Platelet-latelet-.
    Archives of internal medicine, 1977, Volume: 137, Issue:6

    Topics: Adult; Aspirin; Blood Platelets; Depression, Chemical; Dipyridamole; Female; Humans; Methylprednisol

1977
Survival following thrombotic thrombocytopenic purpura in pregnancy.
    Obstetrics and gynecology, 1977, Volume: 50, Issue:1 Suppl

    Topics: Adult; Aspirin; Blood Coagulation Tests; Blood Transfusion; Blood Urea Nitrogen; Cesarean Section; D

1977
Thrombotic thrombocytopenic purpura: A case report.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1978, Volume: 61, Issue:2

    Topics: Adult; Aspirin; Female; Humans; Purpura, Thrombotic Thrombocytopenic

1978
Thrombotic thrombocytopenic purpura: treatment with a combination of antiplatelet drugs.
    Acta medica Scandinavica, 1979, Volume: 205, Issue:5

    Topics: Aspirin; Blood Platelets; Dextrans; Dipyridamole; Disseminated Intravascular Coagulation; Drug Evalu

1979
Thrombotic thrombocytopenic purpura: failure of plasma infusion and antiplatelet agents.
    Annals of internal medicine, 1979, Volume: 90, Issue:6

    Topics: Adult; Aspirin; Blood Platelets; Dipyridamole; Drug Therapy, Combination; Evaluation Studies as Topi

1979
Antiplatelet treatment in septic shock with severe bleeding and thrombocytopenia.
    Thrombosis and haemostasis, 1977, Aug-31, Volume: 38, Issue:2

    Topics: Adult; Aminocaproic Acid; Aspirin; Dipyridamole; Female; Humans; Lysine; Platelet Aggregation; Purpu

1977
Thrombotic thrombocytopenic purpura--remission following splenectomy. Report of a case and review of the literature.
    The American journal of medicine, 1976, Volume: 61, Issue:3

    Topics: Adolescent; Aspirin; Dipyridamole; Humans; Male; Mycoplasma Infections; Purpura, Thrombotic Thromboc

1976
Thrombotic thrombocytopenic purpura: a multimodality model of treatment including plasma exchange, i.v. immunoglobulin, prednisone, antiplatelet agents, vincristine and splenectomy.
    Infusionstherapie und Transfusionsmedizin, 1992, Volume: 19, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Combined Modality Therapy; Dipyridamole; Female; Hematocrit

1992
Antiplatelet therapy in thrombotic thrombocytopenic purpura.
    Lancet (London, England), 1992, Oct-03, Volume: 340, Issue:8823

    Topics: Administration, Oral; Adult; Aspirin; Dipyridamole; Female; Humans; Puerperal Disorders; Purpura, Th

1992
[Kidney diseases associated with hemolytic uremic syndrome,thrombotic thrombocytopenic purpura and disseminated intravascular coagulation].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1992, Jan-10, Volume: 81, Issue:1

    Topics: Adolescent; Adult; Aspirin; Dipyridamole; Disseminated Intravascular Coagulation; Female; Hemolytic-

1992
Erythromelalgia in a patient with thrombotic thrombocytopenic purpura.
    Journal of the American Academy of Dermatology, 1992, Volume: 26, Issue:5 Pt 2

    Topics: Aged; Aspirin; Erythromelalgia; Female; Foot Diseases; Humans; Platelet Aggregation; Platelet Aggreg

1992
Thrombotic thrombocytopenic purpura in early pregnancy with maternal and fetal survival.
    Annals of hematology, 1992, Volume: 64, Issue:5

    Topics: Adult; Aspirin; Biomarkers; Dipyridamole; Female; Humans; Infant, Newborn; L-Lactate Dehydrogenase;

1992
[Thrombotic thrombocytopenic purpura: a benign disease with a very severe acute phase].
    Nederlands tijdschrift voor geneeskunde, 1990, Mar-03, Volume: 134, Issue:9

    Topics: Adult; Aspirin; Combined Modality Therapy; Drug Therapy, Combination; Female; Humans; Plasmapheresis

1990
Plasma exchange and thrombotic thrombocytopenic purpura, the Indiana University Medical Center experience.
    Progress in clinical and biological research, 1990, Volume: 337

    Topics: Adolescent; Adult; Aspirin; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Plasma Excha

1990
[Thrombotic thrombocytopenic purpura. Treatment with anti-thrombocyte drugs].
    Ugeskrift for laeger, 1986, Nov-24, Volume: 148, Issue:48

    Topics: Aged; Aspirin; Blood Platelets; Dextrans; Dipyridamole; Humans; Male; Middle Aged; Prednisolone; Pre

1986
Successful pregnancies of two patients with relapsing thrombotic thrombocytopenic purpura.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 1989, Volume: 29, Issue:4

    Topics: Adult; Aspirin; Blood Transfusion; Combined Modality Therapy; Dipyridamole; Drug Therapy, Combinatio

1989
Thrombotic microangiopathy of the miscellaneous secondary type responding to plasma exchange in a liver transplant recipient.
    The International journal of artificial organs, 1988, Volume: 11, Issue:2

    Topics: Aspirin; Dipyridamole; Humans; Liver Transplantation; Male; Middle Aged; Plasma Exchange; Postoperat

1988
Treatment of aspirin overdose.
    Journal of clinical apheresis, 1988, Volume: 4, Issue:1

    Topics: Adult; Aspirin; Female; Humans; Plasma Exchange; Purpura, Thrombotic Thrombocytopenic

1988
Thrombotic thrombocytopenic purpura: treatment with plasmapheresis.
    American journal of hematology, 1987, Volume: 24, Issue:4

    Topics: Adrenal Cortex Hormones; Adult; Aged; Aspirin; Combined Modality Therapy; Dipyridamole; Female; Foll

1987
Thrombotic thrombocytopenic purpura in early pregnancy.
    Obstetrics and gynecology, 1985, Volume: 66, Issue:2

    Topics: Adult; Aspirin; Combined Modality Therapy; Dipyridamole; Female; Gestational Age; Hematocrit; Humans

1985
Aspirin and prednisone in microangiopathic haemolytic anaemia.
    Lancet (London, England), 1970, Jul-25, Volume: 2, Issue:7665

    Topics: Adult; Anemia, Hemolytic; Aspirin; Blood Platelet Disorders; Blood Urea Nitrogen; Erythrocytes, Abno

1970
Thrombotic thrombocytopenic purpura. Survival following treatment with aspirin, dipyridamole, and prednisone.
    JAMA, 1974, May-27, Volume: 228, Issue:9

    Topics: Acute Disease; Adolescent; Aspirin; Blood Platelets; Dipyridamole; Drug Synergism; Hemoglobins; Huma

1974
Thrombotic thrombocytopenic purpura; treatment with antiplatelet agents.
    The American journal of the medical sciences, 1974, Volume: 268, Issue:2

    Topics: Adult; Aspirin; Blood Cell Count; Blood Coagulation; Blood Platelets; Dextrans; Erythrocyte Count; F

1974
Treatment of thrombotic thrombocytopenic purpura with antiplatelet drugs.
    Blood, 1973, Volume: 42, Issue:1

    Topics: Adolescent; Aspirin; Blood Cell Count; Blood Coagulation Tests; Blood Platelets; Cell Aggregation; D

1973
Thrombotic thrombocytopenic purpura--coagulation parameters in twelve patients.
    Blood, 1973, Volume: 42, Issue:4

    Topics: Adolescent; Adult; Anemia, Hemolytic; Antigens; Aspirin; Blood Coagulation; Blood Coagulation Tests;

1973
Thrombotic thrombocytopenic purpura. A ten-year survey.
    JAMA, 1973, Nov-05, Volume: 226, Issue:6

    Topics: Acute Disease; Adrenal Cortex Hormones; Adult; Aspirin; Biopsy; Chronic Disease; Dextrans; Female; F

1973
Platelet disorders. Advances in understanding and management.
    Postgraduate medicine, 1974, Volume: 55, Issue:5

    Topics: Aspirin; Blood Platelet Disorders; Blood Platelets; Blood Transfusion; Cell Membrane; Humans; Platel

1974
Thrombotic thrombocytopenic purpura. Three cases with platelet and fibrinogen survival studies.
    The Journal of pediatrics, 1974, Volume: 84, Issue:4

    Topics: Adolescent; Antibodies; Aspirin; Blood Coagulation Tests; Blood Platelets; Cell Survival; Child; Chr

1974
Effect of dipyridamole and aspirin in thrombotic microangiopathy.
    British medical journal, 1972, Feb-26, Volume: 1, Issue:5799

    Topics: Adult; Anemia, Hemolytic; Aspirin; Dipyridamole; Humans; Male; Platelet Adhesiveness; Purpura, Throm

1972
Antiplatelet therapy for thrombotic thrombocytopenic purpura.
    The New England journal of medicine, 1971, Aug-12, Volume: 285, Issue:7

    Topics: Aspirin; Blood Cell Count; Blood Platelets; Dipyridamole; Female; Humans; Hydrocortisone; Middle Age

1971