Page last updated: 2024-10-23

aspirin and Purpura, Thrombocytopenic

aspirin has been researched along with Purpura, Thrombocytopenic in 40 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Purpura, Thrombocytopenic: Any form of purpura in which the PLATELET COUNT is decreased. Many forms are thought to be caused by immunological mechanisms.

Research Excerpts

ExcerptRelevanceReference
" A prolonged bleeding time is observed: (1) in thrombopathic thrombocytopenia, which may be (a) hereditary or (b) acquired, as in the immune types or from depression of bone marrow, and (2) athrombocytopenically, as in von Willebrand's disease, Glanzmann's thrombasthenia, or from aspirin intolerance."3.65The bleeding time as a test of hemostatic function. ( Quick, AJ, 1975)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199036 (90.00)18.7374
1990's2 (5.00)18.2507
2000's1 (2.50)29.6817
2010's1 (2.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schmidt, T1
Tsakiris, DA1
Grapow, M1
Siegemund, M1
NIEWEG, HO2
BOUMA, HG2
DEVRIES, K1
JANSZ, A1
Gunther, K1
DANEO, V1
DANEO SISTO, L1
Terragna, A1
Spirito, L1
Conti, L1
Fidani, P1
Chistolini, A1
Francesconi, M1
Gandolfo, GM1
Mazzucconi, MG1
Takayama, H1
Okuma, M1
Uchino, H1
Suehiro, A1
Yoshimoto, H1
Higasa, S1
Kakishita, E1
Carnelli, V1
Pizzi, E1
Jankovic, M1
Sticca, M1
Tolot, F1
Prost, G1
Guignot, B1
Pelletier, M1
Ekert, H1
Waters, KD1
Gugler, E1
Chediak, J1
Telfer, MC1
Vander Laan, B1
Maxey, B1
Cohen, I1
Weiss, HJ2
Tschopp, TB1
Baumgartner, HR1
Quick, AJ2
Pevine, PL1
Stuart, MJ1
Murphy, S1
Oski, FA1
Welborn, JL1
O'Donnell, R1
Hsieh, T1
Eatherton, J1
Aspry, K1
Jarczok, K1
Hołowiecki, J1
De Gaetano, G2
Vermylen, J2
Verstraete, M2
Becker, GA1
Aster, RH2
Harker, LA1
Slichter, SJ1
Galanda, V1
Buchanec, J1
McBride, JA1
Wallett, LH1
Amorosi, EL1
Pisciotta, AV1
Winckelmann, G1
Thiel, E1
Dörmer, P1
Kunze, E1
Thierfelder, S1
Dacie, JV1
Willis, AL1
Schwartz, AD1
Garg, SK1
Sarker, CR1
Hampton, JW1
Cronberg, S1
Caen, JP1
Costello, JM1
Shannon, FT1
Canseco, C1
Weenink-de Vries, J1
Snijder, JA1

Reviews

5 reviews available for aspirin and Purpura, Thrombocytopenic

ArticleYear
Platelet transfusion therapy.
    The Medical clinics of North America, 1972, Volume: 56, Issue:1

    Topics: Anemia, Aplastic; Antigens; Aspirin; Blood Banks; Blood Group Antigens; Blood Platelet Disorders; Bl

1972
The clinical relevance of platelet function tests.
    British journal of haematology, 1972, Volume: 23

    Topics: Adenosine Diphosphate; Aspirin; Blood Cell Count; Blood Coagulation Factors; Blood Coagulation Tests

1972
Acute manifestations of platelet dysfunction.
    The Medical clinics of North America, 1973, Volume: 57, Issue:6

    Topics: Acute Disease; Adenosine Diphosphate; Aspirin; Blood Coagulation Factors; Blood Coagulation Tests; B

1973
Idiosyncratic hematologic reactions to drugs.
    Postgraduate medicine, 1974, Volume: 55, Issue:5

    Topics: Agranulocytosis; Anemia, Aplastic; Anemia, Hemolytic; Anemia, Hypochromic; Anemia, Macrocytic; Aspir

1974
[Blood platelet diseases].
    Medizinische Klinik, 1973, Jan-12, Volume: 68, Issue:2

    Topics: Adenosine Diphosphate; Afibrinogenemia; Aspirin; Blood Platelet Disorders; Blood Platelets; Diagnosi

1973

Other Studies

35 other studies available for aspirin and Purpura, Thrombocytopenic

ArticleYear
[Thrombotic microangiopathy after extracorporeal circulation: important differential diagnosis].
    Der Anaesthesist, 2011, Volume: 60, Issue:5

    Topics: ADAM Proteins; ADAMTS13 Protein; Aged, 80 and over; Aortic Diseases; Aspirin; Coma; Critical Care; D

2011
HAEMATOLOGICAL SIDE-EFFECTS OF SOME ANTI-RHEUMATIC DRUGS.
    Annals of the rheumatic diseases, 1963, Volume: 22

    Topics: Aminopyrine; Antirheumatic Agents; Aspirin; Blood Platelets; Chloroquine; Colchicine; Complement Fix

1963
Successful pregnancy despite thrombotic thrombocytopenic purpura in the first trimester.
    Transfusion, 2006, Volume: 46, Issue:8

    Topics: Anti-Inflammatory Agents; Aspirin; Blood Component Transfusion; Dexamethasone; Female; Humans; Live

2006
Thrombocytopenic purpura from acetyl salicylic acid.
    Minerva medica, 1948, Dec-08, Volume: 39, Issue:49 Pt 2

    Topics: Aspirin; Humans; Purpura, Thrombocytopenic

1948
[Thrombocytopenic purpura in an infant after administration of acetylsalicylic acid to the wet-nurse].
    Minerva pediatrica, 1967, Mar-31, Volume: 19, Issue:13

    Topics: Aspirin; Breast Feeding; Female; Humans; Infant; Purpura, Thrombocytopenic

1967
Detection of drug-dependent IgG antibodies with antiplatelet activity by the antiglobulin consumption assay.
    Haemostasis, 1984, Volume: 14, Issue:6

    Topics: Adolescent; Adult; Aminopyrine; Anti-Bacterial Agents; Aspirin; Autoantibodies; Blood Platelets; Chi

1984
The recovery of platelet malondialdehyde production after a single intake of aspirin--the effect of dosage.
    Thrombosis and haemostasis, 1982, Aug-24, Volume: 48, Issue:1

    Topics: Adrenal Cortex Hormones; Adult; Arachidonic Acids; Aspirin; Blood Platelets; Dose-Response Relations

1982
Platelet aggregating activity of plasma in patients with thrombotic thrombocytopenic purpura evaluated by a particle counting method using light scattering.
    International journal of hematology, 1999, Volume: 70, Issue:1

    Topics: Adolescent; Adult; Aspirin; Dipyridamole; Female; Humans; Light; Male; Middle Aged; Particle Size; P

1999
[Infantile thrombopenias and drugs].
    Minerva pediatrica, 1978, Sep-15, Volume: 30, Issue:17

    Topics: Anti-Bacterial Agents; Antimalarials; Aspirin; Child; Child, Preschool; Drug-Related Side Effects an

1978
[Multiple manifestations of intolerance of a combination of anti-inflammatory drugs. Role of phenylbutazone].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1975, Dec-09, Volume: 51, Issue:48

    Topics: Anti-Inflammatory Agents; Aspirin; Chemical and Drug Induced Liver Injury; Duodenal Ulcer; Erythema;

1975
Hematologic emergencies in children.
    Paediatrician, 1978, Volume: 7, Issue:4-5

    Topics: Acute Disease; Acute Kidney Injury; Adolescent; Anemia, Aplastic; Anemia, Hemolytic, Autoimmune; Asp

1978
[Thrombocyte function and its disorders].
    Das Medizinische Laboratorium, 1979, Volume: 32, Issue:4

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Aspirin; Blood Platelet Disorders; Blood Platelets;

1979
Cycles of agglutination-disagglutination induced by ristocetin in thrombasthenic platelets.
    British journal of haematology, 1979, Volume: 43, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adolescent; Adult; Aspirin; Child; Child, Preschool;

1979
Impaired interaction (adhesion-aggregation) of platelets with the subendothelium in storage-pool disease and after aspirin ingestion. A comparison with von Willebrand's disease.
    The New England journal of medicine, 1975, Sep-25, Volume: 293, Issue:13

    Topics: Adenosine Diphosphate; Administration, Oral; Adolescent; Adult; Animals; Aorta, Abdominal; Aspirin;

1975
The bleeding time as a test of hemostatic function.
    American journal of clinical pathology, 1975, Volume: 64, Issue:1

    Topics: Aspirin; Blood Coagulation; Blood Coagulation Disorders; Blood Coagulation Factors; Blood Coagulatio

1975
Editorial: Platelet-function tests: predictive value.
    The New England journal of medicine, 1975, Jun-19, Volume: 292, Issue:25

    Topics: Aspirin; Blood Platelets; Cell Survival; Humans; Lipids; Methods; Peroxides; Platelet Aggregation; P

1975
A simple nonradioisotope technic for the determination of platelet life-span.
    The New England journal of medicine, 1975, Jun-19, Volume: 292, Issue:25

    Topics: Aspirin; Blood Platelets; Cell Survival; Chromium Radioisotopes; Chronic Disease; Epinephrine; Ethyl

1975
Vincristine for thrombocytopenic purpura.
    Lancet (London, England), 1991, Feb-09, Volume: 337, Issue:8737

    Topics: Adult; Aspirin; Christianity; Dipyridamole; Drug Administration Schedule; Female; Humans; Platelet C

1991
[Acute thrombopenic purpura after the administration of Polopirin].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1985, Apr-22, Volume: 40, Issue:16

    Topics: Acute Disease; Adult; Aspirin; Female; Humans; Purpura, Thrombocytopenic

1985
Platelet aggregation by a specific human immunoglobulin preparation.
    Thrombosis et diathesis haemorrhagica, 1970, Dec-31, Volume: 24, Issue:3

    Topics: ABO Blood-Group System; Adenine Nucleotides; Adult; Antibodies; Antimycin A; Aspirin; Azathioprine;

1970
The bleeding time as a screening test for evaluation of platelet function.
    The New England journal of medicine, 1972, Jul-27, Volume: 287, Issue:4

    Topics: Adult; Aspirin; Blood Cell Count; Blood Coagulation Tests; Blood Platelet Disorders; Blood Platelets

1972
[Etiopathogenesis of various hemorrhagic conditions in children].
    Ceskoslovenska pediatrie, 1974, Volume: 29, Issue:8

    Topics: Adolescent; Aspirin; Child; Drug Hypersensitivity; Female; Food Hypersensitivity; Gastrointestinal H

1974
[Thrombocytopenic purpura with platelet antibodies against acetylsalicylic acid].
    Klinische Wochenschrift, 1973, Aug-01, Volume: 51, Issue:15

    Topics: Acute Disease; Aspirin; Autoantibodies; Blood Cell Count; Blood Platelets; Complement Fixation Tests

1973
[Hemolytic-uremic syndrome and microangiopathic hemolytic anemia].
    Recenti progressi in medicina, 1973, Volume: 54, Issue:1

    Topics: Adrenal Cortex Hormones; Anemia, Hemolytic; Aspirin; Dextrans; Dipyridamole; Drug Hypersensitivity;

1973
A congenital defect in platelet prostaglandin production associated with impaired hemostasis in storage pool disease.
    Prostaglandins, 1973, Volume: 4, Issue:6

    Topics: Aspirin; Blood Cell Count; Blood Platelet Disorders; Blood Platelets; Chromatography, Thin Layer; Co

1973
A method for demonstrating shortened platelet survival utilizing recovery from aspirin effect.
    The Journal of pediatrics, 1974, Volume: 84, Issue:3

    Topics: Aspirin; Blood Cell Count; Blood Platelets; Cell Survival; Humans; Platelet Adhesiveness; Purpura, T

1974
Aspirin-induced thrombocytopenia on an immune basis.
    The American journal of the medical sciences, 1974, Volume: 267, Issue:2

    Topics: Aged; Antibodies; Aspirin; Blood Cell Count; Blood Platelets; Drug Hypersensitivity; Humans; Male; P

1974
Platelet disorders. Advances in understanding and management.
    Postgraduate medicine, 1974, Volume: 55, Issue:5

    Topics: Aspirin; Blood Platelet Disorders; Blood Platelets; Blood Transfusion; Cell Membrane; Humans; Platel

1974
Bleeding disorders during surgery.
    International anesthesiology clinics, 1974,Spring, Volume: 12, Issue:1

    Topics: Adrenal Cortex Hormones; Aspirin; Blood Coagulation Disorders; Blood Coagulation Factors; Blood Coag

1974
Release reaction in washed platelet suspensions induced by kaolin and other particles.
    Scandinavian journal of haematology, 1971, Volume: 8, Issue:2

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Aspirin; Blood Platelet Disorders; Blood Platelets; Calc

1971
Drugs and children.
    The New Zealand medical journal, 1968, Volume: 67, Issue:430

    Topics: Aminophylline; Aspirin; Atropine; Cardiomyopathies; Cataract; Child, Preschool; Chloramphenicol; Chl

1968
Dissociation between platelet factor 3 availability and platelet aggregation.
    Acta medica Scandinavica. Supplementum, 1971, Volume: 525

    Topics: Absorption; Adenosine; Adenosine Diphosphate; Aspirin; Blood Platelets; Collagen; Glycolysis; Humans

1971
The vascular component in hemostasis.
    The New England journal of medicine, 1970, Jul-23, Volume: 283, Issue:4

    Topics: Adult; Aged; Aspirin; Blood Coagulation Tests; Blood Vessels; Female; Hemorrhagic Disorders; Hemosta

1970
[Allergic purpuras].
    Gaceta medica de Mexico, 1969, Volume: 99, Issue:2

    Topics: Adult; Aspirin; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Purpura, Thrombocytopenic;

1969
The occurrence of antibodies against acetylsalicylic acid and related compounds in thrombocytopenic purpura.
    British journal of haematology, 1969, Volume: 17, Issue:3

    Topics: Animals; Antibodies; Aspirin; Blood Coagulation Tests; Drug Hypersensitivity; Humans; Purpura, Throm

1969