aspirin has been researched along with Postpartum Hemorrhage in 22 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Postpartum Hemorrhage: Excess blood loss from uterine bleeding associated with OBSTETRIC LABOR or CHILDBIRTH. It is defined as blood loss greater than 500 ml or of the amount that adversely affects the maternal physiology, such as BLOOD PRESSURE and HEMATOCRIT. Postpartum hemorrhage is divided into two categories, immediate (within first 24 hours after birth) or delayed (after 24 hours postpartum).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The APPEC study is a large-population randomized controlled trial in China evaluating the role of low-dose aspirin prophylactic treatment for pre-eclampsia." | 9.69 | Low-dose aspirin in the prevention of pre-eclampsia in China: postpartum hemorrhage in subgroups of women according to their characteristics and potential bleeding risk. ( Chen, J; Huai, J; Li, B; Lin, L; Yang, H; Zhu, Y, 2023) |
| "Compared with aspirin alone, low-dose aspirin combined with calcium supplementation was more effective in preventing preeclampsia, reduced the risk of preterm birth and postpartum hemorrhage, and promoted fetal growth." | 9.41 | Clinical efficacy of low-dose aspirin combined with calcium in preventing preeclampsia: A systematic review and meta-analysis. ( Chen, WY; Sun, SF, 2023) |
| "Diagnosis of preeclampsia; adverse pregnancy health outcomes and complications including eclampsia, perinatal mortality, preterm birth, small for gestational age, and potential bleeding harms or infant/child harms from aspirin exposure." | 9.12 | Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force. ( Henderson, JT; Redmond, N; Senger, CA; Thomas, RG; Vesco, KK, 2021) |
| "Our purpose was to determine the frequency and safety of the use of epidural anesthesia and the correlation between bleeding time and maternal-neonatal bleeding complications in a group of pregnant women who participated in a multicenter trial of low-dose aspirin in pregnancy." | 9.08 | Low-dose aspirin in nulliparous women: safety of continuous epidural block and correlation between bleeding time and maternal-neonatal bleeding complications. National Institute of Child Health and Human Developmental Maternal-Fetal Medicine Network. ( Caritis, SN; McNellis, D; Shaw, K; Sibai, BM; Thom, E, 1995) |
| "This study aimed to investigate whether aspirin use during pregnancy is associated with an increased risk of bleeding complications." | 8.02 | Aspirin use during pregnancy and the risk of bleeding complications: a Swedish population-based cohort study. ( Bergman, L; Hastie, R; Hesselman, S; Sandström, A; Tong, S; Wikström, AK, 2021) |
| "When aspirin was initiated at > 16 weeks, with a dosage of < 100 mg/day aspirin, there was a lesser preventive effect (RR = 0." | 6.82 | The role of aspirin dose and initiation time in the prevention of preeclampsia and corresponding complications: a meta-analysis of RCTs. ( Dai, C; He, Q; Huang, X; Lee, W; Li, L; Li, R; Luo, Z; Mok, TN; Yip, KC; Zeng, W, 2022) |
| " This suggests that use of LDA outside the recommended guidelines should be cautioned and further investigation is needed to determine its ideal dosing and timing of discontinuation." | 5.91 | Low-Dose Aspirin during Pregnancy and Postpartum Bleeding. ( Culhane, JF; Lundsberg, LS; Merriam, AA; Partridge, C; Reddy, UM; Son, M; White, KJ, 2023) |
| "The APPEC study is a large-population randomized controlled trial in China evaluating the role of low-dose aspirin prophylactic treatment for pre-eclampsia." | 5.69 | Low-dose aspirin in the prevention of pre-eclampsia in China: postpartum hemorrhage in subgroups of women according to their characteristics and potential bleeding risk. ( Chen, J; Huai, J; Li, B; Lin, L; Yang, H; Zhu, Y, 2023) |
| "The association between aspirin use during pregnancy and the risk of postpartum hemorrhage remains unclear." | 5.41 | Low-dose asprin use during pregnancy may be a potential risk for postpartum hemorrhage and increased blood loss: a systematic review and meta-analysis. ( Chen, Y; Chen, Z; Ding, W; Du, Y; Fang, C; Feng, L; Gao, P; He, M; Jiang, Y; Su, R; Wang, S; Wei, L; Yu, J; Zhang, H; Zhang, J; Zhou, X; Zhu, S, 2023) |
| "Compared with aspirin alone, low-dose aspirin combined with calcium supplementation was more effective in preventing preeclampsia, reduced the risk of preterm birth and postpartum hemorrhage, and promoted fetal growth." | 5.41 | Clinical efficacy of low-dose aspirin combined with calcium in preventing preeclampsia: A systematic review and meta-analysis. ( Chen, WY; Sun, SF, 2023) |
| "Diagnosis of preeclampsia; adverse pregnancy health outcomes and complications including eclampsia, perinatal mortality, preterm birth, small for gestational age, and potential bleeding harms or infant/child harms from aspirin exposure." | 5.12 | Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force. ( Henderson, JT; Redmond, N; Senger, CA; Thomas, RG; Vesco, KK, 2021) |
| "Our purpose was to determine the frequency and safety of the use of epidural anesthesia and the correlation between bleeding time and maternal-neonatal bleeding complications in a group of pregnant women who participated in a multicenter trial of low-dose aspirin in pregnancy." | 5.08 | Low-dose aspirin in nulliparous women: safety of continuous epidural block and correlation between bleeding time and maternal-neonatal bleeding complications. National Institute of Child Health and Human Developmental Maternal-Fetal Medicine Network. ( Caritis, SN; McNellis, D; Shaw, K; Sibai, BM; Thom, E, 1995) |
| "This study aimed to investigate whether aspirin use during pregnancy is associated with an increased risk of bleeding complications." | 4.02 | Aspirin use during pregnancy and the risk of bleeding complications: a Swedish population-based cohort study. ( Bergman, L; Hastie, R; Hesselman, S; Sandström, A; Tong, S; Wikström, AK, 2021) |
| "When aspirin was initiated at > 16 weeks, with a dosage of < 100 mg/day aspirin, there was a lesser preventive effect (RR = 0." | 2.82 | The role of aspirin dose and initiation time in the prevention of preeclampsia and corresponding complications: a meta-analysis of RCTs. ( Dai, C; He, Q; Huang, X; Lee, W; Li, L; Li, R; Luo, Z; Mok, TN; Yip, KC; Zeng, W, 2022) |
| " This suggests that use of LDA outside the recommended guidelines should be cautioned and further investigation is needed to determine its ideal dosing and timing of discontinuation." | 1.91 | Low-Dose Aspirin during Pregnancy and Postpartum Bleeding. ( Culhane, JF; Lundsberg, LS; Merriam, AA; Partridge, C; Reddy, UM; Son, M; White, KJ, 2023) |
| "Treatment with aspirin prolonged induction-abortion time by about 9 hours and treatment with indomethacin by 30 hours." | 1.25 | Letter to the editor: Non steroid anti-inflammatory drugs and pregnancy. ( Tricomi, V; Waltman, R, 1974) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (22.73) | 18.7374 |
| 1990's | 5 (22.73) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (13.64) | 24.3611 |
| 2020's | 9 (40.91) | 2.80 |
| Authors | Studies |
|---|---|
| Henderson, JT | 1 |
| Vesco, KK | 1 |
| Senger, CA | 1 |
| Thomas, RG | 1 |
| Redmond, N | 1 |
| Yip, KC | 1 |
| Luo, Z | 1 |
| Huang, X | 1 |
| Lee, W | 1 |
| Li, L | 1 |
| Dai, C | 1 |
| Zeng, W | 1 |
| Mok, TN | 1 |
| He, Q | 1 |
| Li, R | 1 |
| Kawaguchi, H | 1 |
| Kanagawa, T | 1 |
| Yamamoto, R | 1 |
| Sasahara, J | 1 |
| Okamoto, Y | 1 |
| Mitsuda, N | 1 |
| Ishii, K | 1 |
| Jiang, Y | 1 |
| Chen, Z | 1 |
| Chen, Y | 1 |
| Wei, L | 1 |
| Gao, P | 1 |
| Zhang, J | 1 |
| Zhou, X | 1 |
| Zhu, S | 1 |
| Zhang, H | 1 |
| Du, Y | 1 |
| Fang, C | 1 |
| Su, R | 1 |
| Wang, S | 1 |
| Yu, J | 1 |
| He, M | 1 |
| Ding, W | 1 |
| Feng, L | 1 |
| Chen, J | 1 |
| Huai, J | 1 |
| Lin, L | 1 |
| Li, B | 1 |
| Zhu, Y | 1 |
| Yang, H | 1 |
| White, KJ | 1 |
| Son, M | 1 |
| Lundsberg, LS | 1 |
| Culhane, JF | 1 |
| Partridge, C | 1 |
| Reddy, UM | 1 |
| Merriam, AA | 1 |
| Chen, WY | 1 |
| Sun, SF | 1 |
| Hastie, R | 1 |
| Tong, S | 1 |
| Wikström, AK | 1 |
| Sandström, A | 1 |
| Hesselman, S | 1 |
| Bergman, L | 1 |
| Gangat, N | 1 |
| Guglielmelli, P | 1 |
| Al-Kali, A | 1 |
| Wolanskyj-Spinner, AP | 1 |
| Camoriano, J | 1 |
| Patnaik, MM | 1 |
| Pardanani, A | 1 |
| Hanson, CA | 1 |
| Vannucchi, AM | 1 |
| Tefferi, A | 1 |
| Yelnik, CM | 1 |
| Lambert, M | 1 |
| Drumez, E | 1 |
| Le Guern, V | 1 |
| Bacri, JL | 1 |
| Guerra, MM | 1 |
| Laskin, CA | 1 |
| Branch, DW | 1 |
| Sammaritano, LR | 1 |
| Morel, N | 1 |
| Guettrot-Imbert, G | 1 |
| Launay, D | 1 |
| Hachulla, E | 1 |
| Hatron, PY | 1 |
| Salmon, JE | 1 |
| Costedoat-Chalumeau, N | 1 |
| Villani, M | 1 |
| Colaizzo, D | 1 |
| Tiscia, GL | 1 |
| Chinni, E | 1 |
| Bodenizza, C | 1 |
| Cascavilla, N | 1 |
| Grandone, E | 1 |
| Roumi, JE | 1 |
| Moukhadder, HM | 1 |
| Graziadei, G | 1 |
| Pennisi, M | 1 |
| Cappellini, MD | 1 |
| Taher, AT | 1 |
| Lavanya, R | 1 |
| Pratap, K | 1 |
| Sibai, BM | 1 |
| Caritis, SN | 1 |
| Thom, E | 1 |
| Shaw, K | 1 |
| McNellis, D | 1 |
| Tatlok, RK | 1 |
| Reubinoff, BE | 1 |
| Eldor, A | 1 |
| Laufer, N | 1 |
| Sadovsky, E | 1 |
| Cohen, AW | 1 |
| Lewis, RB | 1 |
| Schulman, JD | 1 |
| Waltman, R | 2 |
| Tricomi, V | 2 |
| Shabanah, EH | 1 |
| Arenas, R | 1 |
| Aiken, JW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Predictors of Pregnancy Outcome in Systemic Lupus Erythematosus (SLE) and Antiphospholipid Syndrome (APS)[NCT00198068] | 700 participants (Anticipated) | Observational | 2003-09-30 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for aspirin and Postpartum Hemorrhage
| Article | Year |
|---|---|
Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Humans; Infant, Newborn; Infant, Small for | 2021 |
The role of aspirin dose and initiation time in the prevention of preeclampsia and corresponding complications: a meta-analysis of RCTs.
Topics: Aspirin; Female; Humans; Infant, Newborn; Platelet Aggregation Inhibitors; Postpartum Hemorrhage; Pr | 2022 |
Low-dose asprin use during pregnancy may be a potential risk for postpartum hemorrhage and increased blood loss: a systematic review and meta-analysis.
Topics: Aspirin; Female; Humans; Postpartum Hemorrhage; Pregnancy; Pregnancy Outcome | 2023 |
Clinical efficacy of low-dose aspirin combined with calcium in preventing preeclampsia: A systematic review and meta-analysis.
Topics: Aspirin; Calcium; Calcium, Dietary; Female; Humans; Hypertension, Pregnancy-Induced; Infant, Newborn | 2023 |
Prenatal care, screening, and complications.
Topics: alpha-Fetoproteins; Aspirin; Blood Transfusion, Autologous; Female; Humans; Mass Screening; Neural T | 1991 |
2 trials available for aspirin and Postpartum Hemorrhage
| Article | Year |
|---|---|
Low-dose aspirin in the prevention of pre-eclampsia in China: postpartum hemorrhage in subgroups of women according to their characteristics and potential bleeding risk.
Topics: Adult; Aspirin; Female; Humans; Incidence; Maternal Age; Postpartum Hemorrhage; Pre-Eclampsia; Pregn | 2023 |
Low-dose aspirin in nulliparous women: safety of continuous epidural block and correlation between bleeding time and maternal-neonatal bleeding complications. National Institute of Child Health and Human Developmental Maternal-Fetal Medicine Network.
Topics: Analysis of Variance; Anesthesia, Epidural; Anesthesia, Obstetrical; Aspirin; Bleeding Time; Blood C | 1995 |
15 other studies available for aspirin and Postpartum Hemorrhage
| Article | Year |
|---|---|
Efficacy of discontinuing the use of low-dose aspirin at 28 weeks of gestation for preventing preeclampsia.
Topics: Aspirin; Female; Fetal Growth Retardation; Humans; Hypertension; Infant, Newborn; Postpartum Hemorrh | 2022 |
Low-Dose Aspirin during Pregnancy and Postpartum Bleeding.
Topics: Adult; Anticoagulants; Aspirin; Female; Humans; Postpartum Hemorrhage; Postpartum Period; Pregnancy; | 2023 |
Aspirin use during pregnancy and the risk of bleeding complications: a Swedish population-based cohort study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cohort Studies; Female; Humans; Postpartum | 2021 |
Pregnancy in patients with myelofibrosis: Mayo-Florence series of 24 pregnancies in 16 women.
Topics: Abortion, Habitual; Adult; Anticoagulants; Aspirin; Diabetes, Gestational; Female; Fetal Death; Hemo | 2021 |
Bleeding complications and antithrombotic treatment in 264 pregnancies in antiphospholipid syndrome.
Topics: Adult; Anticoagulants; Antiphospholipid Syndrome; Aspirin; Blood Loss, Surgical; Blood Transfusion; | 2018 |
Postpartum haemorrhage in a woman with essential thrombocythemia carrying calreticulin mutation: a case report.
Topics: Adult; Aspirin; Calreticulin; Female; Fibrinolytic Agents; Humans; Mutation; Postpartum Hemorrhage; | 2016 |
Pregnancy in β-thalassemia intermedia at two tertiary care centers in Lebanon and Italy: A follow-up report on fetal and maternal outcomes.
Topics: Abortion, Habitual; Abortion, Spontaneous; Aspirin; beta-Thalassemia; Birth Weight; Cesarean Section | 2017 |
Aspirin and maternal or neonatal hemostasis.
Topics: Aspirin; Female; Hemorrhage; Hemostasis; Humans; Infant, Newborn; Infant, Newborn, Diseases; Materna | 1983 |
Can low-dose acetylsalicylic acid cause disseminated intravascular coagulation?
Topics: Adult; Aspirin; Disseminated Intravascular Coagulation; Female; Fetal Growth Retardation; Humans; Po | 1995 |
[Characteristics of thrombocyte metabolism in puerperae with massive blood loss and gestosis and possible ways of its metabolic correction].
Topics: Aspirin; Blood Platelets; Drug Combinations; Female; Glycogen; Humans; Lipid Peroxidation; Phospholi | 1992 |
Maternal hemorrhagic complications following prophylactic low-dose aspirin and dipyridamole therapy.
Topics: Adult; Aspirin; Bleeding Time; Blood Component Transfusion; Blood Transfusion; Dipyridamole; Drug Th | 1992 |
Influence of acetylsalicylic acid, an inhibitor of prostaglandin synthesis, on the duration of human gestation and labour.
Topics: Adult; Aspirin; Birth Weight; Female; Humans; Infant, Newborn; Labor, Obstetric; Postpartum Hemorrha | 1973 |
The effect of anti-inflammatory drugs on parturition parameters in the rat.
Topics: Acetates; Animals; Aspirin; Cortisone; Depression, Chemical; Female; Fetal Death; Gestational Age; L | 1973 |
Letter to the editor: Non steroid anti-inflammatory drugs and pregnancy.
Topics: Anti-Inflammatory Agents; Aspirin; Blood Platelets; Female; Fetus; Homeostasis; Humans; Indomethacin | 1974 |
Aspirin and indomethacin prolong parturition in rats: evidence that prostaglandins contribute to expulsion of fetus.
Topics: Administration, Oral; Animals; Aspirin; Biological Assay; Chickens; Chromatography, Thin Layer; Fema | 1972 |