Page last updated: 2024-10-23

aspirin and Polyps

aspirin has been researched along with Polyps in 13 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Polyps: Discrete abnormal tissue masses that protrude into the lumen of the DIGESTIVE TRACT or the RESPIRATORY TRACT. Polyps can be spheroidal, hemispheroidal, or irregular mound-shaped structures attached to the MUCOUS MEMBRANE of the lumen wall either by a stalk, pedunculus, or by a broad base.

Research Excerpts

ExcerptRelevanceReference
" Using patient samples from the randomized, placebo-controlled phase III selenium/celecoxib (Sel/Cel) trial for the prevention of colorectal adenomatous polyps, we analyzed plasma concentrations of 74 oxylipins in a subset of participants who received celecoxib (n = 90) or placebo (n = 95)."5.27Celecoxib use and circulating oxylipins in a colon polyp prevention trial. ( Alberts, DS; Hammock, BD; Lance, P; Martinez, JA; Roe, DJ; Schriewer, A; Thompson, PA; Wertheim, BC; Yang, J, 2018)
"It was the aim of this study to investigate the prevalence of otologic manifestations in a cohort of Samter's syndrome patients (nasal polyps with chronic rhinosinusitis, aspirin intolerance and asthma)."3.75Otologic manifestations in Samter's syndrome. ( Caversaccio, M; Häusler, R; Helbling, A, 2009)
"Aspirin was the most prospective chemopreventive agents for colorectal polyp, colon and rectal carcinoma for its capability of reducing the risk of cardio-cerebral vascular disease as well."1.31[Nonsteroidal anti-inflammatory drugs and the risk of polyposis, colon carcinoma and rectal carcinoma]. ( Gao, X; Li, M; Song, S; Sun, F; Sun, H; Sun, S; Zhang, W, 2002)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19903 (23.08)18.7374
1990's4 (30.77)18.2507
2000's2 (15.38)29.6817
2010's4 (30.77)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Martinez, JA1
Yang, J1
Wertheim, BC1
Roe, DJ1
Schriewer, A1
Lance, P1
Alberts, DS1
Hammock, BD1
Thompson, PA1
Dekker, E1
Kaminski, MF1
Danış, N1
Tekin, F1
Caversaccio, M1
Häusler, R1
Helbling, A1
Shen, J1
Peterson, M1
Mafee, M1
Nguyen, QT1
Gao, X1
Sun, S1
Sun, F1
Li, M1
Sun, H1
Zhang, W1
Song, S1
Hedman, SE1
Andersson, RG1
Bellussi, L1
Capano, EM1
Passàli, D1
Kennedy, DW1
Braun, JJ1
Haas, F1
Conraux, C1
Thomassin, JM1
Korchia, D1
Henderson, LL1
Swedlund, HA1
Van Dellen, RG1
Marcoux, JP1
Carryer, HM1
Peters, GA1
Gleich, GJ1
McDonald, JR1
Mathison, DA1
Stevenson, DD1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Efficacy of Debridement of the Sinus Cavity Following Primary Functional Endoscopic Sinus Surgery (FESS): A Randomized Controlled Trial.[NCT04093193]150 participants (Anticipated)Interventional2018-06-22Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for aspirin and Polyps

ArticleYear
Aural polyps in Samter's triad: case report and literature review.
    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2012, Volume: 33, Issue:5

    Topics: Aspirin; Asthma; Drug Hypersensitivity; Ear Diseases; Ear Neoplasms; Female; Humans; Mastoid; Middle

2012
[Polyposis of the nasal sinuses. Epidemiology and clinical aspects of 350 cases. Treatment and results with a follow-up over 5 years on 93 cases].
    Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Societe d'oto-laryngologie des hopitaux de Paris, 1992, Volume: 109, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Asthma; Child; Drug Hypersensitivity; Ethmoid S

1992
[Nasosinusal polyposis. Indications. Results. Apropos of 222 ethmoidectomies].
    Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Societe d'oto-laryngologie des hopitaux de Paris, 1991, Volume: 108, Issue:8

    Topics: Adult; Aged; Aspirin; Asthma; Drug Hypersensitivity; Ethmoid Sinus; Female; Humans; Male; Middle Age

1991

Trials

1 trial available for aspirin and Polyps

ArticleYear
Celecoxib use and circulating oxylipins in a colon polyp prevention trial.
    PloS one, 2018, Volume: 13, Issue:4

    Topics: Adenomatous Polyps; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Blood

2018

Other Studies

9 other studies available for aspirin and Polyps

ArticleYear
Take a pill for no more polyps: is it that simple?
    Lancet (London, England), 2018, 12-15, Volume: 392, Issue:10164

    Topics: Adenoma; Aspirin; Colorectal Neoplasms; Double-Blind Method; Eicosapentaenoic Acid; Humans; Polyps

2018
Eicosapentaenoic acid and aspirin for colorectal adenomas.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2019, Volume: 30, Issue:2

    Topics: Adenoma; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colorectal Neoplasms; Double-Blind Method

2019
Otologic manifestations in Samter's syndrome.
    ORL; journal for oto-rhino-laryngology and its related specialties, 2009, Volume: 71, Issue:1

    Topics: Aspirin; Asthma; Chronic Disease; Cohort Studies; Drug Hypersensitivity; Ear Diseases; Ear, Middle;

2009
[Nonsteroidal anti-inflammatory drugs and the risk of polyposis, colon carcinoma and rectal carcinoma].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 2002, Volume: 36, Issue:5

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colorectal Neoplasms; Female; Humans; Ibupr

2002
Release of biological mediators by tartrazine from human leukocytes and polyps.
    Acta pharmacologica et toxicologica, 1983, Volume: 52, Issue:2

    Topics: Aspirin; Azo Compounds; Drug Hypersensitivity; Histamine Release; Humans; Leukocytes; Polyps; Tartra

1983
[Out considerations on the etiopathogenesis of nasal-sinus polyposis].
    Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale, 1994, Volume: 14 Suppl 43

    Topics: Aspirin; Drug Tolerance; Humans; Immunoglobulin A; Immunoglobulin E; Immunoglobulin G; Immunoglobuli

1994
Prognostic factors, outcomes and staging in ethmoid sinus surgery.
    The Laryngoscope, 1992, Volume: 102, Issue:12 Pt 2 Su

    Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Drug Hypersensitivity; Endoscopy; Ethmoid Sinus; Ethmoid S

1992
Evaluation of IgE tests in an allergy practice.
    The Journal of allergy and clinical immunology, 1971, Volume: 48, Issue:6

    Topics: Aspirin; Asthma; Drug Hypersensitivity; Food Hypersensitivity; Humans; Immunoglobulin E; Immunoglobu

1971
Aspirin intolerance in asthma. Detection by oral challenge.
    The Journal of allergy and clinical immunology, 1972, Volume: 50, Issue:4

    Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Female; Glucocorticoids; Humans; Male; Polyps; Respir

1972