aspirin has been researched along with Polymyalgia Rheumatica in 17 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Polymyalgia Rheumatica: A syndrome in the elderly characterized by proximal joint and muscle pain, high erythrocyte sedimentation rate, and a self-limiting course. Pain is usually accompanied by evidence of an inflammatory reaction. Women are affected twice as commonly as men and Caucasians more frequently than other groups. The condition is frequently associated with GIANT CELL ARTERITIS and some theories pose the possibility that the two diseases arise from a single etiology or even that they are the same entity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We suggest that polymyalgia rheumatica with giant cell arteritis (PR-GCA) is an arachidonic acid metabolites mediated disease which can be diagnosed more accurately and monitored more precisely for therapeutic benefits by the serial determinations of the major urinary prostaglandin F, serum urinary lysozymes, serum acid phosphatase, and serum angiotensin converting enzyme rather than by the erythrocyte sedimentation rate, and, when necessary by temporal artery biopsy." | 3.66 | Polymyalgia rheumatica and giant cell arteritis--rational diagnosis and treatment predicated and disordered prostaglandin metabolism. ( Fleischman, JA; Henry, RL; Nalbandian, RM; O'Donnell, FE; Reeser, FH; Williams, GA, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (82.35) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schmidt, WA | 1 |
| Weyand, CM | 1 |
| Goronzy, JJ | 1 |
| Wouters, JM | 1 |
| Nalbandian, RM | 1 |
| Henry, RL | 1 |
| Williams, GA | 1 |
| Fleischman, JA | 1 |
| O'Donnell, FE | 1 |
| Reeser, FH | 1 |
| Calkins, E | 1 |
| Chuang, TY | 1 |
| Hunder, GG | 1 |
| Ilstrup, DM | 1 |
| Kurland, LT | 1 |
| Nielsen, IL | 1 |
| Rasmussen, S | 1 |
| Hilden, T | 1 |
| Bienenstock, H | 1 |
| Fernando, KR | 1 |
| Katona, G | 1 |
| Hart, FD | 1 |
| Kolodny, AL | 1 |
| Klipper, AR | 1 |
| Foad, BS | 1 |
| Sheon, RP | 1 |
| Kirsner, AB | 1 |
| Richards, AJ | 1 |
| Gordon, DA | 1 |
| Kraag, G | 1 |
| Cosh, JA | 1 |
| Vojtìsek, O | 1 |
| Kankovà, D | 1 |
| Scott, JT | 1 |
| Davison, S | 1 |
| Spiera, H | 1 |
| Plotz, CM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Study of the Benefit of Early Treatment With an Endothelin Inhibitor (Bosentan) in Patients With Sudden Blindness Due to Giant Cell Arteritis: CECIBO[NCT03841734] | Phase 3 | 8 participants (Anticipated) | Interventional | 2019-03-31 | Not yet recruiting | ||
| VCRC Imaging Protocol for Magnetic Resonance and Positron Emission Tomography in Large-vessel Vasculitis (Takayasu's Arteritis):Development as Clinical Trial Outcome Measures[NCT00744952] | 26 participants (Actual) | Observational | 2008-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for aspirin and Polymyalgia Rheumatica
| Article | Year |
|---|---|
[Polymyalgia rheumatica and giant cell arteritis. New aspects in diagnosis and treatment].
Topics: Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diagnosis, Differe | 2008 |
Medium- and large-vessel vasculitis.
Topics: Adolescent; Adrenal Cortex Hormones; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Aspirin; Dru | 2003 |
Medium- and large-vessel vasculitis.
Topics: Adolescent; Adrenal Cortex Hormones; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Aspirin; Dru | 2003 |
Medium- and large-vessel vasculitis.
Topics: Adolescent; Adrenal Cortex Hormones; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Aspirin; Dru | 2003 |
Medium- and large-vessel vasculitis.
Topics: Adolescent; Adrenal Cortex Hormones; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Aspirin; Dru | 2003 |
Arthritis in the elderly. An overview.
Topics: Adolescent; Adult; Aged; Aging; Anti-Inflammatory Agents; Arthritis; Arthritis, Infectious; Arthriti | 1976 |
[Polymyalgia rheumatica (comprehensive review)].
Topics: Age Factors; Aspirin; Blood Protein Electrophoresis; Blood Sedimentation; Diagnosis, Differential; G | 1973 |
Advances in the treatment of rheumatic disorders.
Topics: Alkylating Agents; Allopurinol; Analgesics; Anti-Inflammatory Agents; Antimalarials; Antimetabolites | 1968 |
1 trial available for aspirin and Polymyalgia Rheumatica
| Article | Year |
|---|---|
Clinical and objective assessments of naproxen through 5 years of clinical experience.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Arthritis, Rheumatoid; Aspirin; Chronic Disease; C | 1975 |
11 other studies available for aspirin and Polymyalgia Rheumatica
| Article | Year |
|---|---|
[Polymyalgia rheumatica and temporal arteritis].
Topics: Aspirin; Fibrinolytic Agents; Giant Cell Arteritis; Glucocorticoids; Humans; Interferon-gamma; Inter | 2005 |
Polymyalgia rheumatica and giant cell arteritis--rational diagnosis and treatment predicated and disordered prostaglandin metabolism.
Topics: Acid Phosphatase; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Sedi | 1981 |
Rheumatic diseases in the elderly. Finding a way through the maze.
Topics: Aged; Arthritis, Rheumatoid; Aspirin; Chondrocalcinosis; Giant Cell Arteritis; Gold; Humans; Medical | 1982 |
Polymyalgia rheumatica: a 10-year epidemiologic and clinical study.
Topics: Age Factors; Aged; Antibodies, Antinuclear; Aspirin; Blood Sedimentation; Female; Glucocorticoids; H | 1982 |
Acetylsalicylic acid and renal function.
Topics: Aged; Aspirin; Bone Diseases; Creatinine; Female; Giant Cell Arteritis; Glomerular Filtration Rate; | 1980 |
Inflammatory disease and its control in rheumatic disorders.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Female; Gout; Hum | 1975 |
Bone and joint diseases in the elderly.
Topics: Activities of Daily Living; Adrenal Cortex Hormones; Age Factors; Aged; Anti-Inflammatory Agents; Ar | 1976 |
Systemic lupus erythematosus in the elderly.
Topics: Aged; Arthritis, Rheumatoid; Aspirin; Female; Humans; Lupus Erythematosus, Systemic; Male; Middle Ag | 1972 |
Letter: Serum-transaminase levels and salicylates.
Topics: Adult; Alkaline Phosphatase; Aspirin; Female; Humans; Liver; Lupus Erythematosus, Systemic; Middle A | 1974 |
Anti-inflammatory drugs in rheumatic diseases.
Topics: Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Aspirin | 1974 |
Polymyalgia rheumatica.
Topics: Aged; Aspirin; Blood Chemical Analysis; Female; Follow-Up Studies; Humans; Male; Middle Aged; Polymy | 1966 |