Page last updated: 2024-10-23

aspirin and Polycythemia Vera

aspirin has been researched along with Polycythemia Vera in 133 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Polycythemia Vera: A myeloproliferative disorder of unknown etiology, characterized by abnormal proliferation of all hematopoietic bone marrow elements and an absolute increase in red cell mass and total blood volume, associated frequently with splenomegaly, leukocytosis, and thrombocythemia. Hematopoiesis is also reactive in extramedullary sites (liver and spleen). In time myelofibrosis occurs.

Research Excerpts

ExcerptRelevanceReference
"The role of aspirin in the antithrombotic strategy of patients with polycythemia vera (PV) and essential thrombocythemia (ET) is highly controversial."10.18Aspirin in polycythemia vera and essential thrombocythemia: current facts and perspectives. ( Landolfi, R; Patrono, C, 1996)
"We enrolled 518 patients with polycythemia vera, no clear indication for aspirin treatment, and no contraindication to such treatment in a double-blind, placebo-controlled, randomized trial to assess the safety and efficacy of prophylaxis with low-dose aspirin (100 mg daily)."9.11Efficacy and safety of low-dose aspirin in polycythemia vera. ( Barbui, T; Gisslinger, H; Kutti, J; Landolfi, R; Marchioli, R; Patrono, C; Tognoni, G, 2004)
" MIAs were frequently preceded or followed by ocular ischemic events of blurred vision, scotomas, transient flashing of the eyes, and sudden transient partial blindness preceded or followed erythromelalgia in the toes or fingers."7.81Aspirin-responsive, migraine-like transient cerebral and ocular ischemic attacks and erythromelalgia in JAK2-positive essential thrombocythemia and polycythemia vera. ( Berneman, Z; De Raeve, H; Gadisseur, A; Lam, KH; Michiels, JJ; Schroyens, W, 2015)
"Increased thromboxane (TX) production and modified aspirin sensitivity has been detected in vitro in platelets isolated from patients with polycythemia vera."7.68Increased thromboxane biosynthesis in patients with polycythemia vera: evidence for aspirin-suppressible platelet activation in vivo. ( Bizzi, B; Castellana, MA; Ciabattoni, G; Landolfi, R; Patrignani, P; Patrono, C; Pogliani, E, 1992)
"Recurrent mesenteric arterial thrombosis developed in a 56-year-old man with polycythemia vera (PV) despite therapy with heparin sodium, warfarin sodium, and standard doses of aspirin and dipyridamole."7.66Polycythemia vera and mesenteric arterial thrombosis. A disease association resulting from decreased platelet sensitivity to aspirin. ( Myers, TJ; Rickles, FR; Steinberg, WM, 1979)
"The role of aspirin in the antithrombotic strategy of patients with polycythemia vera (PV) and essential thrombocythemia (ET) is highly controversial."6.18Aspirin in polycythemia vera and essential thrombocythemia: current facts and perspectives. ( Landolfi, R; Patrono, C, 1996)
"Rates of hemorrhage were similar for aspirin in combination with warfarin or direct-acting oral anticoagulants."5.72Hemorrhage in patients with polycythemia vera receiving aspirin with an anticoagulant: a prospective, observational study. ( Colucci, PM; Grunwald, MR; Lessen, DS; Paranagama, D; Zwicker, JI, 2022)
"We enrolled 518 patients with polycythemia vera, no clear indication for aspirin treatment, and no contraindication to such treatment in a double-blind, placebo-controlled, randomized trial to assess the safety and efficacy of prophylaxis with low-dose aspirin (100 mg daily)."5.11Efficacy and safety of low-dose aspirin in polycythemia vera. ( Barbui, T; Gisslinger, H; Kutti, J; Landolfi, R; Marchioli, R; Patrono, C; Tognoni, G, 2004)
"In the past, management of polycythemia vera (PV) was built upon a cornerstone of control over erythrocytosis, through therapeutic phlebotomy, as well as the use of low-dose aspirin."4.89Polycythemia vera: current pharmacotherapy and future directions. ( Geyer, H; Hensley, B; Mesa, R, 2013)
" An algorithm for the treatment of patients with erythremia is proposed along with recommendations on the use of aspirin, hydroxyurea, alpha-interpheron, and imatinib."4.88[True polycythemia: current views of pathogenesis, diagnostics and treatment]. ( Bakhteeva, TD; Kalinkina, NV; Skliannaia, EV; Taradin, GG; Vatutin, NT, 2012)
" Randomized studies have shown that the risk of thrombosis was significantly reduced in ET with the use of hydroxyurea (HU) and in PV with the use of chlorambucil or 32P."4.80Treatment of polycythaemia vera and essential thrombocythaemia. ( Silverstein, MN; Tefferi, A, 1998)
" MIAs were frequently preceded or followed by ocular ischemic events of blurred vision, scotomas, transient flashing of the eyes, and sudden transient partial blindness preceded or followed erythromelalgia in the toes or fingers."3.81Aspirin-responsive, migraine-like transient cerebral and ocular ischemic attacks and erythromelalgia in JAK2-positive essential thrombocythemia and polycythemia vera. ( Berneman, Z; De Raeve, H; Gadisseur, A; Lam, KH; Michiels, JJ; Schroyens, W, 2015)
" Post-2005 diagnosed patients were also more or less likely to receive aspirin and cytoreductive therapy, respectively, and, despite their older age distribution, displayed significantly lower risk of thrombosis in high risk disease."3.81Patterns of presentation and thrombosis outcome in patients with polycythemia vera strictly defined by WHO-criteria and stratified by calendar period of diagnosis. ( Barbui, T; Carobbio, A; Finazzi, G; Gisslinger, H; Pardanani, A; Passamonti, F; Pieri, L; Rambaldi, A; Randi, ML; Rodeghiero, F; Rumi, E; Tefferi, A; Thiele, J; Vannucchi, AM, 2015)
"This study was designed to compare the oxidative stress parameters of patients with polycythemia vera (PV) to those of healthy volunteers and to investigate the probable relationship between vascular events and parameters of oxidative status such as total oxidative status (TOS), total antioxidant status, oxidative stress index (OSI) and malondialdehyde (MDA) in PV patients."3.80The thrombotic events in polycythemia vera patients may be related to increased oxidative stress. ( Akalin, I; Alver, A; Durmus, A; Mentese, A; Sumer, A; Topal, C; Yilmaz, M, 2014)
"Increased thromboxane (TX) production and modified aspirin sensitivity has been detected in vitro in platelets isolated from patients with polycythemia vera."3.68Increased thromboxane biosynthesis in patients with polycythemia vera: evidence for aspirin-suppressible platelet activation in vivo. ( Bizzi, B; Castellana, MA; Ciabattoni, G; Landolfi, R; Patrignani, P; Patrono, C; Pogliani, E, 1992)
"Recurrent mesenteric arterial thrombosis developed in a 56-year-old man with polycythemia vera (PV) despite therapy with heparin sodium, warfarin sodium, and standard doses of aspirin and dipyridamole."3.66Polycythemia vera and mesenteric arterial thrombosis. A disease association resulting from decreased platelet sensitivity to aspirin. ( Myers, TJ; Rickles, FR; Steinberg, WM, 1979)
" Twenty-four hours after an uncomplicated procedure she had a severe bleeding diathesis following the ingestion of a small amount of aspirin."3.66Salicylate-induced bleeding problem in ophthalmic plastic surgery. ( Paris, GL; Waltuch, GF, 1982)
"Pregnancy is not contraindicated in MPNs, and we recommend aspirin throughout pregnancy with consideration for prophylactic postpartum anticoagulation."2.72Management Issues and Controversies in Low-Risk Patients with Essential Thrombocythemia and Polycythemia Vera. ( Hobbs, G; How, J, 2021)
"Controlled studies are needed to confirm the clinical outcome value of twice-daily vs once-daily aspirin dosing and the therapeutic role of pegylated interferons and direct oral anticoagulants."2.66Polycythemia vera and essential thrombocythemia: 2021 update on diagnosis, risk-stratification and management. ( Barbui, T; Tefferi, A, 2020)
"An absolute erythrocytosis is present when the red cell mass is greater than 125 % of the predicted value for sex and body mass."2.53Investigation and Management of Erythrocytosis. ( McMullin, MF, 2016)
"Polycythemia vera (PV) and essential thrombocythemia (ET) are myeloproliferative neoplasms, respectively characterized by erythrocytosis and thrombocytosis."2.52Polycythemia vera and essential thrombocythemia: 2015 update on diagnosis, risk-stratification and management. ( Barbui, T; Tefferi, A, 2015)
"Treatment with busulfan or interferon-α is usually effective in hydroxyurea failures."2.48Polycythemia vera and essential thrombocythemia: 2012 update on diagnosis, risk stratification, and management. ( Tefferi, A, 2012)
"Having eliminated the common entity polycythemia vera, further direction for investigation is guided by the erythropoietin level."2.45Idiopathic erythrocytosis: a disappearing entity. ( McMullin, MF, 2009)
"The principal risks of essential thrombocythemia include thrombosis, major hemorrhage, and conversion to leukemia or myelofibrosis."2.41Therapeutic options for essential thrombocythemia and polycythemia vera. ( Solberg, LA, 2002)
"Erythromelalgia was localized in the forefoot sole and toes in 28, the fingertips in 9, the handpalm in 2."2.39Erythromelalgic, thrombotic and hemorrhagic manifestations in 50 cases of thrombocythemia. ( Lindemans, J; Michiels, JJ; van Genderen, PJ; van Vliet, HH, 1996)
"Bleeding and thrombosis are major causes of morbidity and mortality in patients with myeloproliferative disorders."2.37Bleeding and thrombosis in the myeloproliferative disorders. ( Schafer, AI, 1984)
"Hydroxyurea was the most frequently used drug followed by ruxolitinib, while interferons were reported for a minority of patients."1.72Cytoreductive treatment in real life: a chart review analysis on 1440 patients with polycythemia vera. ( Crodel, CC; Heidel, FH; Jacobasch, L; Jentsch-Ullrich, K; Palandri, F; Reiser, M; Sauer, A; Tesch, H; Ulshöfer, T; Wunschel, R, 2022)
"Rates of hemorrhage were similar for aspirin in combination with warfarin or direct-acting oral anticoagulants."1.72Hemorrhage in patients with polycythemia vera receiving aspirin with an anticoagulant: a prospective, observational study. ( Colucci, PM; Grunwald, MR; Lessen, DS; Paranagama, D; Zwicker, JI, 2022)
"Risk of thrombosis is higher in JAK2-mutated ET."1.51Polycythemia vera and essential thrombocythemia: 2019 update on diagnosis, risk-stratification and management. ( Barbui, T; Tefferi, A, 2019)
"Polycythemia Vera (PV) and essential thrombocythemia (ET) are myeloproliferative neoplasms respectively characterized by erythrocytosis and thrombocytosis; other disease features include leukocytosis, splenomegaly, thrombosis, bleeding, microcirculatory symptoms, pruritus, and risk of leukemic or fibrotic transformation."1.46Polycythemia vera and essential thrombocythemia: 2017 update on diagnosis, risk-stratification, and management. ( Barbui, T; Tefferi, A, 2017)
"Mechanical valve thrombosis is a rare condition in an adequately anticoagulated patient in the absence of underlying thrombophilia."1.37Anticoagulant-resistant thrombophilia in a patient with polycythemia vera: a case report. ( Cherian, SV; Das, S; Gajra, A; Garcha, AS; Jasti, S; Karachiwala, H, 2011)
"The myeloproliferative disorders have been the "poor cousins" in the family of hematological malignancies for some time."1.33Platelets and thrombosis in myeloproliferative diseases. ( Harrison, CN, 2005)
"Polycythemia vera is an extremely uncommon disease in childhood and for this reason its treatment is not well established."1.31Polycythemia vera in a 12-year-old girl: a case report. ( Atabay, B; Oniz, H; Ozer, EA; Turker, M; Yaprak, I, 2002)
"Lawrence and the use of 32P as a treatment for polycythemia vera, to the formation of French and Italian polycythemia study groups."1.30Polycythemia vera: a retrospective and reprise. ( Berlin, NI; Wasserman, LR, 1997)
"Hydroxyurea was given to patients with ET with a positive history for major vascular complications or with an extreme thrombocytosis."1.30Acute coronary disease in essential thrombocythemia and polycythemia vera. ( Girolami, A; Randi, ML; Rinaldi, V; Rossi, C; Zerbinati, P, 1998)
"One pregnancy was electively terminated after extensive thrombosis in the splanchnic district requiring surgical entero-resection."1.29Primary thrombocythemia and pregnancy: treatment and outcome in fifteen cases. ( Arrigoni, L; Muggiasca, ML; Pagliaro, P; Poggio, M; Rossi, E; Russo, U, 1996)
"Erythromelalgia was the presenting symptom in 26 of 40 patients with thrombocythemia in its primary form or when associated with polycythemia vera."1.27Erythromelalgia caused by platelet-mediated arteriolar inflammation and thrombosis in thrombocythemia. ( Abels, J; Michiels, JJ; Steketee, J; van Vliet, HH; Vuzevski, VD, 1985)

Research

Studies (133)

TimeframeStudies, this research(%)All Research%
pre-199027 (20.30)18.7374
1990's15 (11.28)18.2507
2000's36 (27.07)29.6817
2010's43 (32.33)24.3611
2020's12 (9.02)2.80

Authors

AuthorsStudies
How, J1
Hobbs, G1
Burattini, M1
Falsetti, L1
Potente, E1
Rinaldi, C1
Bartolini, M1
Buratti, L1
Silvestrini, M1
Viticchi, G1
Crodel, CC1
Jentsch-Ullrich, K1
Reiser, M1
Jacobasch, L1
Sauer, A1
Tesch, H1
Ulshöfer, T1
Wunschel, R1
Palandri, F1
Heidel, FH1
Goulart, H1
Mascarenhas, J3
Tremblay, D1
Edahiro, Y2
Nicol, C1
Ajzenberg, N1
Lacut, K1
Couturaud, F1
Lippert, E1
Pan-Petesch, B1
Ianotto, JC1
Mora, B1
Passamonti, F3
Khodier, M1
Gadó, K1
Tefferi, A11
Barbui, T16
Zwicker, JI1
Paranagama, D2
Lessen, DS1
Colucci, PM1
Grunwald, MR1
Choi, HS1
Hong, J1
Hwang, SM1
Lee, JH1
Ma, Y1
Kim, SA1
Lee, JY1
Lee, JO1
Bang, SM1
Parasuraman, S1
Yu, J1
Shrestha, S1
Wang, L1
Baser, O1
Scherber, R1
Griesshammer, M4
Kiladjian, JJ2
Besses, C2
Elli, EM1
Diral, E1
Gambacorti-Passerini, C1
Calori, R1
Carmosino, I1
Breccia, M1
Latagliata, R1
Di Veroli, A1
Hensley, B1
Geyer, H1
Mesa, R2
Squizzato, A2
Romualdi, E2
Middeldorp, S2
Panova-Noeva, M1
Marchetti, M1
Russo, L1
Tartari, CJ1
Leuzzi, A1
Finazzi, G10
Rambaldi, A2
ten Cate, H1
Falanga, A1
Pecci, A1
Croci, G1
Balduini, CL1
Boveri, E1
Durmus, A1
Mentese, A1
Yilmaz, M1
Sumer, A1
Akalin, I1
Topal, C1
Alver, A1
Michiels, JJ9
Berneman, Z4
Gadisseur, A1
Lam, KH1
De Raeve, H1
Schroyens, W4
Alvarez-Larrán, A1
Yoshimoto, G1
Miyamoto, T1
Vannucchi, AM3
Carobbio, A1
Thiele, J2
Rumi, E1
Gisslinger, H4
Rodeghiero, F2
Randi, ML3
Pieri, L1
Pardanani, A1
Abdel-Rahman, I1
Murphy, C1
Kremyanskaya, M2
Hoffman, R2
Aumiller, J1
Keohane, C1
McLornan, DP1
Sanchez, K1
Connor, C1
Radia, D1
Harrison, CN3
Stein, BL1
Oh, ST1
Berenzon, D1
Hobbs, GS1
Rampal, RK1
Abboud, CN1
Adler, K1
Heaney, ML1
Jabbour, EJ1
Komrokji, RS1
Moliterno, AR1
Ritchie, EK1
Rice, L1
Ahlawat, A1
Jun-O'Connell, A1
Salameh, J1
Reneau, JC1
Patnaik, MM1
Reiter, A1
Harrison, C1
McMullin, MF2
Rao, K1
Shenoy, SB1
Kamath, Y1
Kapoor, S1
Gameiro, RS1
Rodrigues, A1
Gonçalves, FM1
Graça, JP1
Santilli, F2
Romano, M1
Recchiuti, A1
Dragani, A2
Falco, A2
Lessiani, G2
Fioritoni, F2
Lattanzio, S1
Mattoscio, D1
De Cristofaro, R1
Rocca, B1
Davì, G2
Nigg, C1
Naumann, UK1
Käser, L1
Struve, S1
Beer, PA1
Green, AR2
Landolfi, R11
Nicolazzi, MA1
Porfidia, A1
Di Gennaro, L5
Ruggeri, M2
Finotto, S1
Fortuna, S1
Robier, C1
Neubauer, M1
Sternad, H1
Quehenberger, F1
Rainer, F1
Neumeister, P1
Mahendradas, P1
Shetty, R1
Avadhani, K1
Ross, C1
Gupta, A1
Shetty, BK1
Carpenedo, M1
Pogliani, EM2
Prodanovic, EM1
Frater, JL1
Burkemper, NM1
Hurley, MY1
Das, S1
Karachiwala, H1
Cherian, SV1
Garcha, AS1
Jasti, S1
Gajra, A1
Ghazali, N1
Collyer, JC1
Tighe, JV1
Finazzi, MC1
Vatutin, NT1
Taradin, GG1
Bakhteeva, TD1
Kalinkina, NV1
Skliannaia, EV1
Bakkour, W1
Motta, L1
Stewart, E1
Lengfelder, E2
Melear, JM1
Goldstein, RM1
Levy, MF1
Molmenti, EP1
Cooper, B1
Netto, GJ1
Klintmalm, GB1
Stone, MJ1
van Urk, H1
Friess, D1
Lämmle, B1
Alberio, L1
Spivak, J1
Marchioli, R6
Kutti, J3
Tognoni, G4
Patrono, C5
Alliot, C1
Dutrillaux, F1
Maynadié, M1
Carli, PM1
Denes, AE1
Elliott, MA2
Caruso, V1
Capnist, G1
Chisesi, T1
Finelli, C1
Gugliotta, L2
Marilus, R1
Villegas, A1
Rossi, D1
Cortini, F1
Deambrogi, C1
Barbieri, C1
Cerri, M1
Franceschetti, S1
Conconi, A1
Capello, D1
Gaidano, G1
Lankipalli, R1
Konkle, B1
Mohler, ER1
Novarese, L1
Silver, RT2
Budde, U1
van Vliet, HH4
De Stefano, V1
Marfisi, R2
Koudstaal, PJ1
Lindemans, J2
Neumann, HA1
Di Nisio, M1
Borrelli, G1
Leone, G1
Porreca, E1
Rutjes, AW1
Wahid, SF1
Md-Anshar, F1
Mukari, SA1
Rahmat, R1
Wilkins, BS1
Erber, WN1
Bareford, D1
Buck, G1
Wheatley, K1
East, CL1
Paul, B1
Campbell, PJ1
Tekin, M1
Gökaslan, S1
Diker, E1
Aydoğdu, S1
Fjellner, B2
Ireland, H1
Lane, DA1
Wolff, S1
Foadi, M1
Schafer, AI1
Fröhli, P1
Graf, C1
Rhyner, K1
Berliner, S1
Shoenfeld, Y1
Shaklai, M1
Pinkhas, J1
Meschengieser, SS1
Woods, AI1
Schattner, MA1
Lazzari, MA1
Paris, GL1
Waltuch, GF1
Pagliaro, P1
Arrigoni, L1
Muggiasca, ML1
Poggio, M1
Russo, U1
Rossi, E1
Ongenae, K1
Janssens, A1
Noens, L1
Wieme, N1
Geerts, ML1
Beele, H1
Naeyaert, JM1
van Genderen, PJ2
Chan, AW1
Drobac, M1
Sternberg, L1
Berlin, NI2
Wasserman, LR3
Willoughby, S1
Pearson, TC2
Rossi, C1
Zerbinati, P1
Rinaldi, V1
Girolami, A1
Stark, P1
Bazzan, M1
Brière, J2
Green, AC1
Fruchtmann, SM1
Hansmann, E1
Wehmeier, A1
Kvasnicka, HM1
Hasselbalch, H1
Cervantes, F1
Silverstein, MN1
Turker, M1
Ozer, EA1
Oniz, H1
Atabay, B1
Yaprak, I1
Solberg, LA1
Hägermark, Ö1
Ranft, K1
Brands, W1
Zannino, L1
Salvadori, G1
Myers, TJ1
Steinberg, WM1
Rickles, FR1
Callis, M1
Ciabattoni, G1
Patrignani, P1
Castellana, MA1
Pogliani, E1
Bizzi, B1
Scheffer, MG1
Simoons, ML1
Roelandt, JR1
Kurihara, A1
Kobayashi, I1
Tamura, K1
Indrák, K1
Kapustová, M1
Hrcková, Y1
Kubis, M1
Scudla, V1
Jezdinský, J1
Kudo, I1
Soejima, K1
Morimoto, S1
Sawada, Y1
Aihara, M1
Yoshida, Y1
Gylling, H1
Ikkala, E1
Rasi, V1
Buelli, M1
Cortelazzo, S1
Viero, P1
De Gaetano, G1
Tartaglia, AP1
Goldberg, JD1
Berk, PD1
Chapman, CS1
Swart, SS1
Wood, JK1
Kovaleva, LG1
Sedova, GT1
Krasiukova, LI1
Abels, J1
Steketee, J1
Vuzevski, VD1
Sahud, MA1
Levin, JM1
Ostrowski, TL1
Gilbert, NS1
Adams, T1
Schutz, L1
Goldberg, L1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prospective, Non-interventional Study of Disease Progression and Treatment of Patients With Polycythemia Vera in United States Academic or Community Clinical Practices[NCT02252159]2,544 participants (Actual)Observational2014-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

46 reviews available for aspirin and Polycythemia Vera

ArticleYear
Management Issues and Controversies in Low-Risk Patients with Essential Thrombocythemia and Polycythemia Vera.
    Current hematologic malignancy reports, 2021, Volume: 16, Issue:5

    Topics: Animals; Aspirin; Disease Management; Female; Humans; Phlebotomy; Platelet Aggregation Inhibitors; P

2021
Ischemic stroke as a presenting manifestation of polycythemia vera: a narrative review.
    Reviews in the neurosciences, 2022, 04-26, Volume: 33, Issue:3

    Topics: Aspirin; Humans; Ischemic Stroke; Janus Kinase 2; Polycythemia Vera; Thrombosis

2022
Low-risk polycythemia vera and essential thrombocythemia: management considerations and future directions.
    Annals of hematology, 2022, Volume: 101, Issue:5

    Topics: Aspirin; Humans; Myeloproliferative Disorders; Polycythemia Vera; Primary Myelofibrosis; Quality of

2022
Treatment options and pregnancy management for patients with PV and ET.
    International journal of hematology, 2022, Volume: 115, Issue:5

    Topics: Aspirin; Female; Humans; Hydroxyurea; Janus Kinase 2; Janus Kinase Inhibitors; Myeloproliferative Di

2022
SOHO State of the Art Updates and Next Questions | Polycythemia Vera: Is It Time to Rethink Treatment?
    Clinical lymphoma, myeloma & leukemia, 2023, Volume: 23, Issue:2

    Topics: Aspirin; Humans; Hydroxyurea; Janus Kinase 2; Middle Aged; Polycythemia Vera; Primary Myelofibrosis;

2023
BCR::ABL1 negative myeloproliferative neoplasms: A review focused on essential thrombocythemia and polycythemia vera.
    Physiology international, 2023, Sep-05, Volume: 110, Issue:3

    Topics: Aspirin; Humans; Hydroxyurea; Mutation; Polycythemia Vera; Thrombocythemia, Essential

2023
Polycythemia vera and essential thrombocythemia: 2021 update on diagnosis, risk-stratification and management.
    American journal of hematology, 2020, Volume: 95, Issue:12

    Topics: Age Factors; Aspirin; Busulfan; Calreticulin; Disease-Free Survival; Humans; Interferon-alpha; Janus

2020
Polycythemia vera: current pharmacotherapy and future directions.
    Expert opinion on pharmacotherapy, 2013, Volume: 14, Issue:5

    Topics: Alkylating Agents; Aspirin; Hematocrit; Hematologic Agents; Hematopoiesis; Humans; Hydroxyurea; Inte

2013
Antiplatelet drugs for polycythaemia vera and essential thrombocythaemia.
    The Cochrane database of systematic reviews, 2013, Apr-30, Issue:4

    Topics: Anticoagulants; Aspirin; Humans; Platelet Aggregation Inhibitors; Polycythemia Vera; Randomized Cont

2013
Antiplatelet therapy in the management of myeloproliferative neoplasms.
    Current hematologic malignancy reports, 2014, Volume: 9, Issue:4

    Topics: Aspirin; Disease Management; Female; Humans; Male; Myeloproliferative Disorders; Platelet Aggregatio

2014
[Treatment strategy for myeloproliferative neoplasms].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2014, Volume: 55, Issue:10

    Topics: Adrenal Cortex Hormones; Aspirin; Calreticulin; Carbamates; Clinical Trials as Topic; Drug Therapy,

2014
Polycythemia vera and essential thrombocythemia: 2015 update on diagnosis, risk-stratification and management.
    American journal of hematology, 2015, Volume: 90, Issue:2

    Topics: Aspirin; Calreticulin; Diagnosis, Differential; Disease Management; Humans; Hydroxyurea; Janus Kinas

2015
Current and future treatment options for polycythemia vera.
    Annals of hematology, 2015, Volume: 94, Issue:6

    Topics: Animals; Aspirin; Forecasting; Humans; Interferon-alpha; Janus Kinase 2; Phlebotomy; Polycythemia Ve

2015
Anagrelide hydrochloride and ruxolitinib for treatment of polycythemia vera.
    Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:8

    Topics: Aspirin; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Hydroxyurea; Interferon-alpha; Nitr

2015
Polycythemia Vera: An Appraisal of the Biology and Management 10 Years After the Discovery of JAK2 V617F.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Nov-20, Volume: 33, Issue:33

    Topics: Aspirin; Clinical Trials, Phase II as Topic; Disease Progression; Female; Humans; Hydroxyurea; Incid

2015
Essential Thrombocythemia and Polycythemia Vera: Focus on Clinical Practice.
    Mayo Clinic proceedings, 2015, Volume: 90, Issue:9

    Topics: Aspirin; Diagnosis, Differential; Disease Management; Disease Progression; Humans; Janus Kinase 2; P

2015
How We Identify and Manage Patients with Inadequately Controlled Polycythemia Vera.
    Current hematologic malignancy reports, 2016, Volume: 11, Issue:5

    Topics: Antineoplastic Agents; Aspirin; Humans; Hydroxyurea; Interferon-alpha; Janus Kinase 2; Nitriles; Pol

2016
Investigation and Management of Erythrocytosis.
    Current hematologic malignancy reports, 2016, Volume: 11, Issue:5

    Topics: Adaptor Proteins, Signal Transducing; Aspirin; Erythropoietin; Humans; Intracellular Signaling Pepti

2016
Evidence and expertise in the management of polycythemia vera and essential thrombocythemia.
    Leukemia, 2008, Volume: 22, Issue:8

    Topics: Aspirin; Humans; Hydroxyurea; Interferon-alpha; Janus Kinase 2; Mutation; Phlebotomy; Polycythemia V

2008
Management of Philadelphia negative chronic myeloproliferative disorders in pregnancy.
    Blood reviews, 2008, Volume: 22, Issue:5

    Topics: Aspirin; Female; Heparin, Low-Molecular-Weight; Humans; Platelet Aggregation Inhibitors; Polycythemi

2008
Insights into the pathogenesis and management of thrombosis in polycythemia vera and essential thrombocythemia.
    Internal and emergency medicine, 2010, Volume: 5, Issue:3

    Topics: Aspirin; Humans; Janus Kinase 2; Leukocytosis; Mutation; Platelet Aggregation Inhibitors; Polycythem

2010
Pathogenesis and management of essential thrombocythemia.
    Hematology. American Society of Hematology. Education Program, 2009

    Topics: Acute Disease; Aged; Aspirin; Clone Cells; Disease Management; Disease Progression; Humans; Hydroxyu

2009
Idiopathic erythrocytosis: a disappearing entity.
    Hematology. American Society of Hematology. Education Program, 2009

    Topics: Adult; Aspirin; Blood Viscosity; Diagnosis, Differential; Erythropoiesis; Erythropoietin; Female; He

2009
Polycythemia vera.
    Internal and emergency medicine, 2010, Volume: 5, Issue:5

    Topics: Aspirin; Disease Progression; Fibrinolytic Agents; Humans; Janus Kinase 2; Mutation; Phlebotomy; Pol

2010
Polycythemia vera and essential thrombocythemia: 2012 update on diagnosis, risk stratification, and management.
    American journal of hematology, 2012, Volume: 87, Issue:3

    Topics: Acute Disease; Age Factors; Alkylating Agents; Anticoagulants; Aspirin; Busulfan; Disease Management

2012
Front-line therapy in polycythemia vera and essential thrombocythemia.
    Blood reviews, 2012, Volume: 26, Issue:5

    Topics: Aspirin; Humans; Phlebotomy; Polycythemia Vera; Risk Factors; Thrombocythemia, Essential

2012
[True polycythemia: current views of pathogenesis, diagnostics and treatment].
    Klinicheskaia meditsina, 2012, Volume: 90, Issue:8

    Topics: Age Factors; Algorithms; Antineoplastic Agents; Aspirin; Benzamides; Combined Modality Therapy; Hema

2012
[Diagnosis and therapy of polycythemia vera in the era of JAK2].
    Deutsche medizinische Wochenschrift (1946), 2013, Volume: 138, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diagnosis, Differential; DNA Mutational Analysis;

2013
Pathogenesis and management of bleeding in essential thrombocythemia and polycythemia vera.
    Current hematology reports, 2004, Volume: 3, Issue:5

    Topics: Aspirin; Bleeding Time; Hemostatics; Humans; Incidence; Platelet Activation; Platelet Aggregation; P

2004
Thrombosis and haemorrhage in polycythaemia vera and essential thrombocythaemia.
    British journal of haematology, 2005, Volume: 128, Issue:3

    Topics: Aged; Aspirin; Hemorrhage; Humans; Hydroxyurea; Middle Aged; Polycythemia Vera; Risk Factors; Thromb

2005
Aspirin for the control of platelet activation and prevention of thrombosis in essential thrombocythemia and polycythemia vera: current insights and rationale for future studies.
    Seminars in thrombosis and hemostasis, 2006, Volume: 32, Issue:3

    Topics: Aspirin; Humans; Myeloproliferative Disorders; Platelet Activation; Polycythemia Vera; Thrombocythem

2006
Risk stratification, staging, and treatment of patients with polycythemia vera: Italian and European collaboration on low-dose aspirin in polycythemia data.
    Seminars in thrombosis and hemostasis, 2006, Volume: 32, Issue:3

    Topics: Aspirin; Cooperative Behavior; Drug Therapy; Europe; Humans; Italy; Phlebotomy; Polycythemia Vera; R

2006
Treatment of polycythemia vera.
    Seminars in thrombosis and hemostasis, 2006, Volume: 32, Issue:4 Pt 2

    Topics: Antineoplastic Agents; Aspirin; Female; Humans; Hydroxyurea; Interferons; Janus Kinase 2; Leukemia;

2006
The paradox of platelet activation and impaired function: platelet-von Willebrand factor interactions, and the etiology of thrombotic and hemorrhagic manifestations in essential thrombocythemia and polycythemia vera.
    Seminars in thrombosis and hemostasis, 2006, Volume: 32, Issue:6

    Topics: Aspirin; Bleeding Time; Blood Platelets; Deamino Arginine Vasopressin; Hemorrhage; Humans; Microcirc

2006
Massive retroperitoneal hematoma with secondary hemothorax complicating bone marrow trephine biopsy in polycythemia vera.
    American journal of hematology, 2007, Volume: 82, Issue:10

    Topics: Aspirin; Biopsy, Needle; Bone Marrow Examination; Female; Hematoma; Hemothorax; Humans; Ilium; Middl

2007
Antiplatelet drugs for polycythaemia vera and essential thrombocythaemia.
    The Cochrane database of systematic reviews, 2008, Apr-16, Issue:2

    Topics: Anticoagulants; Aspirin; Humans; Platelet Aggregation Inhibitors; Polycythemia Vera; Randomized Cont

2008
Bleeding and thrombosis in the myeloproliferative disorders.
    Blood, 1984, Volume: 64, Issue:1

    Topics: Alkylating Agents; Arachidonic Acids; Aspirin; Blood Viscosity; Epinephrine; Hematocrit; Hemorrhage;

1984
Erythromelalgic, thrombotic and hemorrhagic manifestations in 50 cases of thrombocythemia.
    Leukemia & lymphoma, 1996, Volume: 22 Suppl 1

    Topics: Adult; Aged; Aspirin; Busulfan; Double-Blind Method; Erythromelalgia; Female; Gangrene; Hemorrhage;

1996
Aspirin in polycythemia vera and essential thrombocythemia: current facts and perspectives.
    Leukemia & lymphoma, 1996, Volume: 22 Suppl 1

    Topics: Adult; Aged; Aspirin; Cyclooxygenase Inhibitors; Erythromelalgia; Female; Fibrinolytic Agents; Human

1996
Erythromelalgia and vascular complications in polycythemia vera.
    Seminars in thrombosis and hemostasis, 1997, Volume: 23, Issue:5

    Topics: Aspirin; Erythromelalgia; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Polycy

1997
The use of aspirin in polycythaemia vera and primary thrombocythaemia.
    Blood reviews, 1998, Volume: 12, Issue:1

    Topics: Arachidonic Acid; Aspirin; Cyclooxygenase Inhibitors; Humans; Platelet Aggregation Inhibitors; Polyc

1998
Diagnosis, pathogenesis and treatment of the myeloproliferative disorders essential thrombocythemia, polycythemia vera and essential megakaryocytic granulocytic metaplasia and myelofibrosis.
    The Netherlands journal of medicine, 1999, Volume: 54, Issue:2

    Topics: Aspirin; Bone Marrow; Bone Marrow Transplantation; Diagnosis, Differential; Follow-Up Studies; Granu

1999
Treatment of polycythaemia vera and essential thrombocythaemia.
    Bailliere's clinical haematology, 1998, Volume: 11, Issue:4

    Topics: Adult; Aged; Aspirin; Chlorambucil; Disease Progression; Female; Hemorrhage; Humans; Hydroxyurea; In

1998
Therapeutic options for essential thrombocythemia and polycythemia vera.
    Seminars in oncology, 2002, Volume: 29, Issue:3 Suppl 10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Busulfan; Fibrinolytic Agen

2002
[Platelet aggregation inhibitors. Their possible use in pediatric pathology].
    Minerva pediatrica, 1979, Jan-31, Volume: 31, Issue:2

    Topics: Age Factors; Anti-Inflammatory Agents; Aspirin; Child; Clofibrate; Dextrans; Diabetes Mellitus, Type

1979
Platelet disorders: a review of disturbances in adhesion, aggregation, and release reaction.
    California medicine, 1972, Volume: 116, Issue:1

    Topics: Adenosine Diphosphate; Afibrinogenemia; Anemia; Aspirin; Blood Platelet Disorders; Connective Tissue

1972

Trials

10 trials available for aspirin and Polycythemia Vera

ArticleYear
Thromboembolic events in polycythemia vera.
    Annals of hematology, 2019, Volume: 98, Issue:5

    Topics: Age Factors; Anticoagulants; Aspirin; Humans; Hydroxyurea; Interferons; Nitriles; Phlebotomy; Polycy

2019
The effects of JAK inhibitor therapy upon novel markers of thrombosis In myeloproliferative neoplasms.
    Haematologica, 2015, Volume: 100, Issue:9

    Topics: Aspirin; Biomarkers; Female; Hematologic Neoplasms; Humans; Janus Kinase 2; Male; Middle Aged; Nitri

2015
Hematologic aspects of liver transplantation for Budd-Chiari syndrome with special reference to myeloproliferative disorders.
    Transplantation, 2002, Oct-27, Volume: 74, Issue:8

    Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Blood Coagulati

2002
Efficacy and safety of low-dose aspirin in polycythemia vera.
    The New England journal of medicine, 2004, Jan-08, Volume: 350, Issue:2

    Topics: Aspirin; Cardiovascular Diseases; Disease-Free Survival; Double-Blind Method; Female; Hemorrhage; Hu

2004
Bone marrow pathology in essential thrombocythemia: interobserver reliability and utility for identifying disease subtypes.
    Blood, 2008, Jan-01, Volume: 111, Issue:1

    Topics: Adult; Antineoplastic Agents; Aspirin; Biopsy; Blood Cell Count; Drug Therapy, Combination; Hematolo

2008
Experimental and clinical pruritus. Studies on some putative peripheral mediators. The influence of ultraviolet light and transcutaneous nerve stimulation.
    Acta dermato-venereologica. Supplementum, 1981, Volume: 97

    Topics: Animals; Aspirin; Electric Stimulation Therapy; Histamine Release; Humans; Intradermal Tests; Mast C

1981
Aspirin in polycythemia vera and essential thrombocythemia: current facts and perspectives.
    Leukemia & lymphoma, 1996, Volume: 22 Suppl 1

    Topics: Adult; Aged; Aspirin; Cyclooxygenase Inhibitors; Erythromelalgia; Female; Fibrinolytic Agents; Human

1996
Low-dose aspirin in polycythaemia vera: a pilot study. Gruppo Italiano Studio Policitemia (GISP).
    British journal of haematology, 1997, Volume: 97, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Fem

1997
European Collaboration on Low-dose Aspirin in Polycythemia Vera (ECLAP): a randomized trial.
    Seminars in thrombosis and hemostasis, 1997, Volume: 23, Issue:5

    Topics: Aspirin; Dose-Response Relationship, Drug; Europe; Feasibility Studies; Female; Follow-Up Studies; H

1997
Pruritus in polycythemia vera: treatment with aspirin and possibility of platelet involvement.
    Acta dermato-venereologica, 1979, Volume: 59, Issue:6

    Topics: Adult; Aged; Aspirin; Blood Platelets; Clinical Trials as Topic; Double-Blind Method; Female; Histam

1979

Other Studies

78 other studies available for aspirin and Polycythemia Vera

ArticleYear
Cytoreductive treatment in real life: a chart review analysis on 1440 patients with polycythemia vera.
    Journal of cancer research and clinical oncology, 2022, Volume: 148, Issue:10

    Topics: Aged; Aspirin; Cytoreduction Surgical Procedures; Humans; Hydroxyurea; Phlebotomy; Polycythemia Vera

2022
Hemorrhages in Polycythemia Vera and Essential Thrombocythemia: Epidemiology, Description, and Risk Factors-Learnings from a Large Cohort.
    Thrombosis and haemostasis, 2022, Volume: 122, Issue:10

    Topics: Aspirin; Hemorrhage; Humans; Hydroxyurea; Male; Polycythemia Vera; Risk Factors; Thrombocythemia, Es

2022
[Recent advances in polycythemia vera treatment].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2020, Volume: 61, Issue:9

    Topics: Aspirin; Clinical Trials as Topic; Humans; Hydroxyurea; Interferon-alpha; Janus Kinase 2; Polycythem

2020
Hemorrhage in patients with polycythemia vera receiving aspirin with an anticoagulant: a prospective, observational study.
    Haematologica, 2022, 05-01, Volume: 107, Issue:5

    Topics: Anticoagulants; Aspirin; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Polycythemia Vera; Pro

2022
Evaluation of the need for cytoreduction and its potential carcinogenicity in children and young adults with myeloproliferative neoplasms.
    Annals of hematology, 2021, Volume: 100, Issue:10

    Topics: Adolescent; Adult; Antineoplastic Agents; Aspirin; Child; Female; Fibrinolytic Agents; Follow-Up Stu

2021
Cytoreductive treatment patterns among US veterans with polycythemia vera.
    BMC cancer, 2018, May-04, Volume: 18, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cytoreduction Surgical Procedures;

2018
Polycythemia vera and essential thrombocythemia: 2019 update on diagnosis, risk-stratification and management.
    American journal of hematology, 2019, Volume: 94, Issue:1

    Topics: Adult; Aspirin; Bone Marrow; Busulfan; Disease Management; Disease Progression; Hemorrhage; Humans;

2019
Management and outcome of 11 pregnancies in women with polycythemia vera.
    Leukemia research, 2019, Volume: 81

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Disease Management; Drug Th

2019
ADP-induced platelet aggregation and thrombin generation are increased in Essential Thrombocythemia and Polycythemia Vera.
    Thrombosis research, 2013, Volume: 132, Issue:1

    Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Female; Humans; Jan

2013
Cutaneous involvement by post-polycythemia vera myelofibrosis.
    American journal of hematology, 2014, Volume: 89, Issue:4

    Topics: Aged; Aspirin; Biopsy; Cell Lineage; Disease Progression; Drug Therapy, Combination; Fibrosis; Hemat

2014
The thrombotic events in polycythemia vera patients may be related to increased oxidative stress.
    Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2014, Volume: 23, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antioxidants; Aspirin; Body Mass Index; Bone Marrow; Case-Control St

2014
Aspirin-responsive, migraine-like transient cerebral and ocular ischemic attacks and erythromelalgia in JAK2-positive essential thrombocythemia and polycythemia vera.
    Acta haematologica, 2015, Volume: 133, Issue:1

    Topics: Adult; Aged; Aspirin; Cerebral Cortex; Erythromelalgia; Eye; Female; Follow-Up Studies; Humans; Isch

2015
Patterns of presentation and thrombosis outcome in patients with polycythemia vera strictly defined by WHO-criteria and stratified by calendar period of diagnosis.
    American journal of hematology, 2015, Volume: 90, Issue:5

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Austria; Female; H

2015
Recurrent ischaemic stroke unveils polycythaemia vera.
    BMJ case reports, 2015, Mar-09, Volume: 2015

    Topics: Aspirin; Atorvastatin; Bloodletting; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutar

2015
New and treatment-relevant risk stratification for thrombosis in essential thrombocythemia and polycythemia vera.
    American journal of hematology, 2015, Volume: 90, Issue:8

    Topics: Age Factors; Aged; Aspirin; Drug Administration Schedule; Enzyme Inhibitors; Fibrinolytic Agents; Hu

2015
[Polycythemia vera: the disadvantages of overproduction].
    MMW Fortschritte der Medizin, 2015, Apr-30, Volume: 157, Issue:8

    Topics: Aged; Aspirin; Bloodletting; Diagnosis, Differential; Female; Hematocrit; Humans; Hydroxyurea; Inter

2015
Pearls & Oy-sters: An isolated cranial nerve 6 palsy as a presentation of polycythemia vera.
    Neurology, 2015, Sep-15, Volume: 85, Issue:11

    Topics: Abducens Nerve Diseases; Aged; Aspirin; Brain; Cranial Nerves; Humans; Male; Polycythemia Vera; Troc

2015
47-Year-Old Man With Pruritus.
    Mayo Clinic proceedings, 2016, Volume: 91, Issue:2

    Topics: Aspirin; Diagnosis, Differential; Disease Management; Hemoglobins; Histamine Antagonists; Humans; Ja

2016
Central retinal artery occlusion as a presenting manifestation of polycythaemia vera.
    BMJ case reports, 2016, Oct-20, Volume: 2016

    Topics: Aspirin; Bone Marrow; Female; Fluorescein Angiography; Fundus Oculi; Hematocrit; Humans; Middle Aged

2016
Polycythemia vera and essential thrombocythemia: 2017 update on diagnosis, risk-stratification, and management.
    American journal of hematology, 2017, Volume: 92, Issue:1

    Topics: Aspirin; Calreticulin; Diagnosis, Differential; Erythropoietin; Humans; Hydroxyurea; Interferon-alph

2017
Bumpy road to the diagnosis of polycythaemia vera.
    BMJ case reports, 2017, Mar-09, Volume: 2017

    Topics: Aged; Anticoagulants; Aspirin; Female; Humans; Phlebotomy; Polycythemia Vera; Pulmonary Embolism; Tr

2017
Circulating endothelial progenitor cells and residual in vivo thromboxane biosynthesis in low-dose aspirin-treated polycythemia vera patients.
    Blood, 2008, Aug-15, Volume: 112, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Aspirin; Blood; Case-Control Studies; Colony-Forming Units

2008
[Thrombocytosis].
    Praxis, 2008, Apr-02, Volume: 97, Issue:7

    Topics: Adult; Aspirin; Biopsy, Needle; Bloodletting; Bone Marrow; Diagnosis, Differential; Female; Hematocr

2008
Soluble CD40 ligand and endothelial dysfunction in aspirin-treated polycythaemia vera patients.
    British journal of haematology, 2009, Volume: 145, Issue:4

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; CD4

2009
Treatment outcome in a cohort of young patients with polycythemia vera.
    Internal and emergency medicine, 2010, Volume: 5, Issue:5

    Topics: Adult; Antineoplastic Agents; Aspirin; Cohort Studies; Combined Modality Therapy; Disease Progressio

2010
Evaluation of platelet function and pharmacological platelet inhibition in patients with myeloproliferative disorders using multiple electrode aggregometry.
    Thrombosis research, 2010, Volume: 126, Issue:3

    Topics: Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Aspirin; Austria; Case-Control Studies; Clopid

2010
Polycythemia vera and increased hemophilic factor VIII causing acute zonal occult outer retinopathy: a case report.
    Ocular immunology and inflammation, 2010, Volume: 18, Issue:4

    Topics: Acute Disease; Aspirin; Electroretinography; Factor VIII; Fluorescein Angiography; Humans; Male; Phl

2010
From Vaquez to Dameshek through JAK…2 much for polycythemia vera to be feared?
    Internal and emergency medicine, 2010, Volume: 5, Issue:5

    Topics: Aspirin; Fibrinolytic Agents; Humans; Janus Kinase 2; Polycythemia Vera; Thrombosis

2010
Pruritic indurated plaques on the legs of a 62-year-old woman--quiz case. Polycythemia vera (PCV).
    Archives of dermatology, 2011, Volume: 147, Issue:1

    Topics: Aspirin; Biopsy; Female; Humans; Hydroxyurea; Janus Kinase 2; Leg; Middle Aged; Point Mutation; Poly

2011
Anticoagulant-resistant thrombophilia in a patient with polycythemia vera: a case report.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2011, Volume: 22, Issue:8

    Topics: Aged; Anticoagulants; Aspirin; Factor Xa; Factor Xa Inhibitors; Fatal Outcome; Heparin, Low-Molecula

2011
Hemimandibulectomy and vascularized fibula flap in bisphosphonate-induced mandibular osteonecrosis with polycythaemia rubra vera.
    International journal of oral and maxillofacial surgery, 2013, Volume: 42, Issue:1

    Topics: Aged, 80 and over; Alendronate; Aspirin; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone De

2013
A case of secondary erythromelalgia with unusual histological findings.
    The American Journal of dermatopathology, 2013, Volume: 35, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biopsy; Erythromelalgia; Humans; Male; Middle Aged

2013
Aspirin-responsive painful red, blue, black toe, or finger syndrome in polycythemia vera associated with thrombocythemia.
    Annals of hematology, 2003, Volume: 82, Issue:3

    Topics: Aged; Aspirin; Busulfan; Erythromelalgia; Female; Fingers; Hematocrit; Humans; Male; Middle Aged; Pl

2003
Qualitative platelet defect and thrombohaemorrhagic complications in a patient with polycythaemia vera. Case 10.
    Hamostaseologie, 2003, Volume: 23, Issue:3

    Topics: Aged; Aspirin; Blood Platelet Disorders; Clopidogrel; Hemorrhage; Humans; Male; Platelet Aggregation

2003
Daily aspirin--only half the answer.
    The New England journal of medicine, 2004, Jan-08, Volume: 350, Issue:2

    Topics: Aspirin; Humans; Phlebotomy; Platelet Aggregation Inhibitors; Platelet Count; Polycythemia Vera; Thr

2004
Low-dose aspirin in polycythemia vera.
    The New England journal of medicine, 2004, Apr-15, Volume: 350, Issue:16

    Topics: Aspirin; Hematocrit; Humans; Multivariate Analysis; Patient Selection; Platelet Aggregation Inhibito

2004
Low-dose aspirin in polycythemia vera.
    The New England journal of medicine, 2004, Apr-15, Volume: 350, Issue:16

    Topics: Aspirin; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Polycythemia Vera; Thrombocythemia, Es

2004
Low-dose aspirin in polycythemia vera.
    The New England journal of medicine, 2004, Apr-15, Volume: 350, Issue:16

    Topics: Aspirin; Cardiovascular Diseases; Erythrocyte Volume; Hematocrit; Humans; Platelet Aggregation Inhib

2004
Acute leukemia in polycythemia vera: an analysis of 1638 patients enrolled in a prospective observational study.
    Blood, 2005, Apr-01, Volume: 105, Issue:7

    Topics: Acute Disease; Adult; Aged; Aspirin; Databases, Factual; Disease Progression; Disease-Free Survival;

2005
Platelets and thrombosis in myeloproliferative diseases.
    Hematology. American Society of Hematology. Education Program, 2005

    Topics: Aspirin; Blood Platelets; Clinical Trials as Topic; Endothelium, Vascular; Hematocrit; Humans; Janus

2005
Usefulness of JAK2V617F mutation in distinguishing idiopathic erythrocytosis from polycythemia vera.
    Leukemia research, 2007, Volume: 31, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Aspirin; Bone Marrow; Diagnosis, Differenti

2007
An unusual case of toe ulceration.
    Vascular medicine (London, England), 2006, Volume: 11, Issue:1

    Topics: Adult; Aspirin; Erythropoietin; Fibrinolytic Agents; Foot Ulcer; Hematocrit; Humans; Hydroxyurea; Ma

2006
Leukocytosis as a major thrombotic risk factor in patients with polycythemia vera.
    Blood, 2007, Mar-15, Volume: 109, Issue:6

    Topics: Aged; Aspirin; Female; Follow-Up Studies; Humans; Leukocyte Count; Leukocytosis; Male; Middle Aged;

2007
Platelet-mediated erythromelalgic, cerebral, ocular and coronary microvascular ischemic and thrombotic manifestations in patients with essential thrombocythemia and polycythemia vera: a distinct aspirin-responsive and coumadin-resistant arterial thromboph
    Platelets, 2006, Volume: 17, Issue:8

    Topics: Aged; Anticoagulants; Aspirin; Drug Resistance; Erythromelalgia; Female; Humans; Ischemia; Male; Mic

2006
The haematocrit and platelet target in polycythemia vera.
    British journal of haematology, 2007, Volume: 136, Issue:2

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Disease Progression; Female; Follow-Up Studi

2007
Prevention of thrombosis in polycythemia vera and essential thrombocythemia.
    Haematologica, 2008, Volume: 93, Issue:3

    Topics: Arterial Occlusive Diseases; Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans;

2008
[Development of acute coronary syndrome in three patients with essential thrombocythemia or polycythemia vera].
    Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2008, Volume: 36, Issue:1

    Topics: Adult; Anticoagulants; Antisickling Agents; Aspirin; Coronary Angiography; Diagnosis, Differential;

2008
In vivo platelet release in myeloproliferative disorders.
    Thrombosis and haemostasis, 1982, Aug-24, Volume: 48, Issue:1

    Topics: Aged; Aspirin; beta-Thromboglobulin; Blood Platelets; Fibrinopeptide A; Fibrinopeptide B; Humans; Mi

1982
[Prevention of vascular complications in polycythemia vera and primary thrombocythemia treated with low doses of acetylsalicylic acid].
    Schweizerische medizinische Wochenschrift, 1983, Nov-05, Volume: 113, Issue:44

    Topics: Aged; Aspirin; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Polycythemia Ver

1983
Conservative treatment of Budd-Chiari syndrome in polycythemia vera.
    Haematologica, 1981, Volume: 66, Issue:2

    Topics: Aspirin; Budd-Chiari Syndrome; Busulfan; Dipyridamole; Female; Furosemide; Humans; Leukapheresis; Mi

1981
[Association of hemorrhagic and thrombotic phenomena in myeloproliferative syndromes].
    Medicina, 1981, Volume: 41 Suppl

    Topics: Adult; Aspirin; Blood Platelet Disorders; Dipyridamole; Female; Humans; Leukemia, Myeloid; Male; Mid

1981
Salicylate-induced bleeding problem in ophthalmic plastic surgery.
    Ophthalmic surgery, 1982, Volume: 13, Issue:8

    Topics: Aspirin; Bleeding Time; Blood Platelets; Eyelid Diseases; Eyelids; Female; Hemorrhage; Humans; Middl

1982
Primary thrombocythemia and pregnancy: treatment and outcome in fifteen cases.
    American journal of hematology, 1996, Volume: 53, Issue:1

    Topics: Adult; Aspirin; Female; Fibrinogen; Fibrinolytic Agents; Gestational Age; Hemoglobins; Heparin; Huma

1996
Erythromelalgia: a clue to the diagnosis of polycythemia vera.
    Dermatology (Basel, Switzerland), 1996, Volume: 192, Issue:4

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Erythromelalgia; Female; Humans; Polycythemi

1996
The management of acute myocardial infarction in a patient with polycythemia rubra vera during the thrombolytic era--does it make a difference?
    The Canadian journal of cardiology, 1997, Volume: 13, Issue:1

    Topics: Adult; Anticoagulants; Aspirin; Cardiac Catheterization; Coronary Angiography; Electrocardiography;

1997
Polycythemia vera: a retrospective and reprise.
    The Journal of laboratory and clinical medicine, 1997, Volume: 130, Issue:4

    Topics: Aspirin; Blood Volume; Controlled Clinical Trials as Topic; Female; Hematocrit; History, 19th Centur

1997
Acute coronary disease in essential thrombocythemia and polycythemia vera.
    Journal of internal medicine, 1998, Volume: 244, Issue:1

    Topics: Adult; Aged; Aging; Antisickling Agents; Aspirin; Female; Follow-Up Studies; Humans; Hydroxyurea; Ma

1998
Myeloproliferative syndromes. Current opinions from the European Hematology Association Working Group on Myeloproliferative Disorders.
    Pathologie-biologie, 2001, Volume: 49, Issue:2

    Topics: Aspirin; Bone Marrow Examination; Clinical Trials as Topic; Clone Cells; Congresses as Topic; Diseas

2001
Polycythemia vera in a 12-year-old girl: a case report.
    Pediatric hematology and oncology, 2002, Volume: 19, Issue:4

    Topics: Aspirin; Child; Drug Therapy, Combination; Female; Hemoglobins; Humans; Hydroxyurea; Leukocyte Count

2002
[Complications of antithrombotic prophylaxis with acetylsalicylic acid (ASS) in polycythemia (author's transl)].
    Medizinische Klinik, 1978, Jun-02, Volume: 73, Issue:22

    Topics: Aged; Aspirin; Female; Gastrointestinal Hemorrhage; Heparin; Humans; Male; Polycythemia Vera; Thromb

1978
Polycythemia vera and mesenteric arterial thrombosis. A disease association resulting from decreased platelet sensitivity to aspirin.
    Archives of internal medicine, 1979, Volume: 139, Issue:6

    Topics: Aspirin; Drug Resistance; Humans; Intestine, Small; Male; Mesenteric Vascular Occlusion; Middle Aged

1979
[Ischemic lesions in polycythaemia vera (author's transl)].
    Sangre, 1977, Volume: 22, Issue:6

    Topics: Aspirin; Dipyridamole; Female; Foot; Humans; Ischemia; Male; Middle Aged; Pain; Polycythemia Vera; S

1977
Increased thromboxane biosynthesis in patients with polycythemia vera: evidence for aspirin-suppressible platelet activation in vivo.
    Blood, 1992, Oct-15, Volume: 80, Issue:8

    Topics: Adult; Aged; Aspirin; Blood Platelets; Female; Humans; Kinetics; Leukotriene E4; Male; Middle Aged;

1992
Thrombocythemia and coronary artery disease.
    American heart journal, 1991, Volume: 122, Issue:2

    Topics: Adult; Aged; Aspirin; Busulfan; Coronary Disease; Female; Humans; Male; Middle Aged; Polycythemia Ve

1991
[Clinical evaluation of the control of antiplatelet therapy through platelet aggregation rate on polycythemia vera associated with thrombocytosis and erythromelalgia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1989, Volume: 30, Issue:1

    Topics: Aspirin; Drug Evaluation; Erythromelalgia; Female; Fingers; Humans; Indomethacin; Middle Aged; Plate

1989
Comparison of the effects of acylpyrin, curantyl and ticlid on some platelet functions in patients with polycythemia vera.
    Acta Universitatis Palackianae Olomucensis Facultatis Medicae, 1985, Volume: 111

    Topics: Adult; Aged; Aspirin; Blood Platelets; Dipyridamole; Female; Humans; Male; Middle Aged; Platelet Agg

1985
[Polycythemia vera associated with erythromelalgia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1988, Volume: 29, Issue:7

    Topics: Adult; Aspirin; Erythromelalgia; Humans; Male; Polycythemia Vera

1988
[Erythromelalgia].
    Duodecim; laaketieteellinen aikakauskirja, 1987, Volume: 103, Issue:15

    Topics: Aged; Aspirin; Erythromelalgia; Female; Humans; Male; Middle Aged; Polycythemia Vera; Thrombocytosis

1987
Aspirin and risk of bleeding in patients with thrombocythemia.
    The American journal of medicine, 1987, Volume: 83, Issue:2

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Adolescent; Adult; Aged; Aspirin; Bleeding Time; Blood P

1987
Adverse effects of antiaggregating platelet therapy in the treatment of polycythemia vera.
    Seminars in hematology, 1986, Volume: 23, Issue:3

    Topics: Aspirin; Dipyridamole; Female; Hemorrhage; Humans; Male; Phosphorus Radioisotopes; Platelet Aggregat

1986
Oesophageal apoplexy associated with aspirin ingestion in polycythaemia rubra vera.
    Clinical and laboratory haematology, 1986, Volume: 8, Issue:3

    Topics: Aged; Aspirin; Cerebrovascular Disorders; Esophagus; Female; Hemorrhage; Humans; Polycythemia Vera

1986
A cooperative study of polycythemia vera.
    Annals of the New York Academy of Sciences, 1985, Volume: 459

    Topics: Aspirin; Chlorambucil; Dipyridamole; Humans; Leukemia; Polycythemia Vera; Prognosis

1985
[Preventive correction of hemostasis in patients with polycythemia vera].
    Gematologiia i transfuziologiia, 1986, Volume: 31, Issue:2

    Topics: Aspirin; Humans; Niacin; Pentoxifylline; Polycythemia Vera; Theobromine; Thrombosis

1986
Erythromelalgia caused by platelet-mediated arteriolar inflammation and thrombosis in thrombocythemia.
    Annals of internal medicine, 1985, Volume: 102, Issue:4

    Topics: Adult; Aged; Analgesics; Arteries; Arterioles; Arteritis; Aspirin; Blood Platelets; Erythromelalgia;

1985
Thrombotic-hemorrhagic diathesis of polycythemia vera treated with aspirin.
    JAMA, 1974, Jul-08, Volume: 229, Issue:2

    Topics: Aspirin; Blood Cell Count; Blood Platelets; Bloodletting; Disseminated Intravascular Coagulation; Fe

1974
Letter: Aspirin treatment in polycythemia.
    JAMA, 1974, Oct-28, Volume: 230, Issue:4

    Topics: Adult; Aspirin; Humans; Male; Polycythemia Vera

1974
Platelet function abnormalities in the myeloproliferative disorders.
    Scandinavian journal of haematology, 1974, Volume: 13, Issue:3

    Topics: Adenosine Diphosphate; Adult; Aged; Aspirin; Blood Cell Count; Blood Platelets; Collagen; Epinephrin

1974
Polycythemia vera complicated by acute leukemia and a rapidly enlarging mass in the left upper abdominal quadrant.
    The American journal of medicine, 1967, Volume: 42, Issue:6

    Topics: Aspirin; Female; Heart Arrest; Humans; Leukemia, Myeloid; Metaraminol; Middle Aged; Polycythemia Ver

1967