aspirin has been researched along with Pleurisy in 35 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Pleurisy: INFLAMMATION of PLEURA, the lining of the LUNG. When PARIETAL PLEURA is involved, there is pleuritic CHEST PAIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, the role of LXA4 and aspirin (ASA)-triggered lipoxins (ATLs) in inflammatory edema formation remains unclear." | 7.73 | Lipoxin A4 inhibits acute edema in mice: implications for the anti-edematogenic mechanism induced by aspirin. ( Calixto, JB; Henriques, Md; Kassuya, CA; Menezes-de-Lima, O; Nascimento, AF, 2006) |
| "Aspirin cannot cause major haemorrhage, but in the elderly it can cause gastrointestinal bleeding via ulceration of the gastrointestinal mucosa." | 5.56 | Additive effect of dabigatran and high-dose aspirin in the development of haemorrhagic pleural effusion in a patient with tuberculous pleuritis. ( Barış, VÖ; Karagül, DA; Karnak, D, 2020) |
| "In carrageenin-induced pleurisy, counts of infiltrated pleural neutrophils in G-CSF-r 5 and 7 h after carrageenin were significantly higher (by 119% and 116%) than those in Vehicle-r." | 5.29 | Increased migration of neutrophils to granulocyte-colony stimulating factor in rat carrageenin-induced pleurisy: roles of complement, bradykinin, and inducible cyclooxygenase-2. ( Harada, Y; Hatanaka, K; Katori, M; Kawamura, M; Majima, M; Ogino, M; Saito, M, 1996) |
| " However, the role of LXA4 and aspirin (ASA)-triggered lipoxins (ATLs) in inflammatory edema formation remains unclear." | 3.73 | Lipoxin A4 inhibits acute edema in mice: implications for the anti-edematogenic mechanism induced by aspirin. ( Calixto, JB; Henriques, Md; Kassuya, CA; Menezes-de-Lima, O; Nascimento, AF, 2006) |
| " As lipoxin A4 (LXA4) and aspirin-triggered 15-epi-LXA4 (ATL) are emerging as endogenous "stop signals" produced in distinct pathologies including some eosinophil-related pulmonary disorders, we evaluated the impact of in situ LXA4/ATL metabolically stable analogues on allergen-induced eosinophilic pleurisy in sensitized rats." | 3.70 | Cutting edge: lipoxin (LX) A4 and aspirin-triggered 15-epi-LXA4 block allergen-induced eosinophil trafficking. ( Bandeira-Melo, C; Bozza, PT; Cordeiro, RS; Diaz, BL; Jose, PJ; Martins, MA; Serhan, CN, 2000) |
| " Of the 21 compounds prepared, two were found to be one-tenth as potent as indomethacin in the pleurisy model and one compound was tested and found to be weakly active in the adjuvant arthritis model." | 3.67 | Antiinflammatory activity of N-(2-benzoylphenyl)alanine derivatives. ( Sancilio, LF; Sleevi, MC; Walsh, DA, 1984) |
| "Aspirin cannot cause major haemorrhage, but in the elderly it can cause gastrointestinal bleeding via ulceration of the gastrointestinal mucosa." | 1.56 | Additive effect of dabigatran and high-dose aspirin in the development of haemorrhagic pleural effusion in a patient with tuberculous pleuritis. ( Barış, VÖ; Karagül, DA; Karnak, D, 2020) |
| " NS-398 and nimesulide dosing did not reduce thromboxane B2 production from platelets isolated from rats with carrageenin-induced pleurisy, demonstrating that at the doses used, cyclooxygenase 2 inhibitors did not inhibit cyclooxygenase 1, as platelets contain only this isoform." | 1.30 | Differential effects of inhibitors of cyclooxygenase (cyclooxygenase 1 and cyclooxygenase 2) in acute inflammation. ( Gilroy, DW; Tomlinson, A; Willoughby, DA, 1998) |
| "In carrageenin-induced pleurisy, counts of infiltrated pleural neutrophils in G-CSF-r 5 and 7 h after carrageenin were significantly higher (by 119% and 116%) than those in Vehicle-r." | 1.29 | Increased migration of neutrophils to granulocyte-colony stimulating factor in rat carrageenin-induced pleurisy: roles of complement, bradykinin, and inducible cyclooxygenase-2. ( Harada, Y; Hatanaka, K; Katori, M; Kawamura, M; Majima, M; Ogino, M; Saito, M, 1996) |
| "Rat pleurisy was induced by intrapleural injection of lambda-carrageenin." | 1.27 | Activation of plasma kallikrein-kinin system and its significant role in pleural fluid accumulation of rat carrageenin-induced pleurisy. ( Harada, Y; Katori, M; Tanaka, K; Uchida, Y; Ueno, A, 1983) |
| "The effects of protein deficiency on the biosynthesis of metabolites of arachidonic acid by rat pleural polymorphonuclear leukocytes stimulated with calcium ionophore were investigated." | 1.27 | Effects of protein deficiency on the metabolism of arachidonic acid by rat pleural polymorphonuclear leukocytes. ( Powell, WS; Varma, DR; Yue, TL, 1983) |
| "Phenacetin was active in the trypsin and kaolin assays with oral ED50's of 114 +/- 36." | 1.26 | Quantitative comparison of the analgesic and anti-inflammatory activities of aspirin, phenacetin and acetaminophen in rodents. ( Selph, JL; Truax, JF; Vinegar, R, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (62.86) | 18.7374 |
| 1990's | 7 (20.00) | 18.2507 |
| 2000's | 4 (11.43) | 29.6817 |
| 2010's | 1 (2.86) | 24.3611 |
| 2020's | 1 (2.86) | 2.80 |
| Authors | Studies |
|---|---|
| Walsh, DA | 1 |
| Sleevi, MC | 1 |
| Sancilio, LF | 1 |
| Karagül, DA | 1 |
| Barış, VÖ | 1 |
| Karnak, D | 1 |
| Savoia, F | 1 |
| Gaddoni, G | 1 |
| Casadio, C | 1 |
| Patrizi, A | 1 |
| Spadola, G | 1 |
| Bassi, P | 1 |
| Albertini, F | 1 |
| Ballardini, G | 1 |
| Briganti, E | 1 |
| Casolari, S | 1 |
| De Donà, D | 1 |
| Menni, B | 1 |
| Zanotti, M | 1 |
| De Angelis, P | 1 |
| Menezes-de-Lima, O | 1 |
| Kassuya, CA | 1 |
| Nascimento, AF | 1 |
| Henriques, Md | 1 |
| Calixto, JB | 1 |
| Fujino, N | 1 |
| Uchida, Y | 2 |
| Tanaka, K | 4 |
| Harada, Y | 7 |
| Ueno, A | 2 |
| Katori, M | 6 |
| Yue, TL | 1 |
| Varma, DR | 1 |
| Powell, WS | 1 |
| Yamashita, K | 2 |
| Ishibashi, M | 3 |
| Miyazaki, H | 3 |
| Vinegar, R | 3 |
| Truax, JF | 3 |
| Selph, JL | 3 |
| Voelker, FA | 1 |
| Oh-Ishi, S | 1 |
| Saldi, M | 1 |
| Yamashita, Y | 1 |
| Hatanaka, K | 3 |
| Majima, M | 2 |
| Kawamura, M | 3 |
| Ohno, T | 2 |
| Aizawa, A | 1 |
| Yamamoto, S | 1 |
| Ogino, M | 2 |
| Saito, M | 2 |
| Bandeira-Melo, C | 2 |
| Singh, Y | 1 |
| Cordeiro, RS | 2 |
| e Silva, PM | 1 |
| Martins, MA | 2 |
| Ogino, K | 1 |
| Yang, Q | 1 |
| Gilroy, DW | 1 |
| Tomlinson, A | 1 |
| Willoughby, DA | 2 |
| Bozza, PT | 1 |
| Diaz, BL | 1 |
| Jose, PJ | 1 |
| Serhan, CN | 1 |
| Louerat, C | 1 |
| Hominal, S | 1 |
| Perol, M | 1 |
| Nesme, P | 1 |
| Guerin, JC | 1 |
| Meacock, SC | 1 |
| Kitchen, EA | 1 |
| Rothkopf, M | 1 |
| Vogel, G | 1 |
| Roch-Arveiller, M | 2 |
| Revelant, V | 1 |
| Pham Huy, D | 1 |
| Maman, L | 2 |
| Fontagne, J | 1 |
| Sorenson, JR | 2 |
| Giroud, JP | 2 |
| Huy, DP | 1 |
| Paegelow, I | 1 |
| Werner, H | 1 |
| Chiabrando, C | 1 |
| Castelli, MG | 1 |
| Cozzi, E | 1 |
| Fanelli, R | 1 |
| Campoleoni, A | 1 |
| Balotta, C | 1 |
| Latini, R | 1 |
| Garattini, S | 1 |
| Di Rosa, M | 2 |
| Sorrentino, L | 1 |
| Parente, L | 1 |
| Wright, MG | 1 |
| Utting, JA | 1 |
| Shreeve, DR | 1 |
| Panush, RS | 1 |
| Franco, AE | 1 |
| Schur, PH | 1 |
| Buckler, RT | 1 |
| Papadimitriou, JM | 1 |
| Vailati, G | 1 |
| Montini, M | 1 |
| Bonicelli, A | 1 |
| Pagani, G | 1 |
| Kok-Jensen, A | 1 |
| Lindeneg, O | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Prospective, Randomized, Double-blind Study Assessing the Efficacy of Intravenous (IV) Ibuprofen Versus IV Acetaminophen for the Treatment of Pain Following Orthopaedic Low Extremity Surgery[NCT03771755] | 62 participants (Actual) | Interventional | 2017-07-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for aspirin and Pleurisy
| Article | Year |
|---|---|
[Postmyocardial infarction syndrome].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diagnosis, Differential; Diagnostic Imaging; Endoc | 2007 |
34 other studies available for aspirin and Pleurisy
| Article | Year |
|---|---|
Antiinflammatory activity of N-(2-benzoylphenyl)alanine derivatives.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Chemical Phenomena; Chemistry | 1984 |
Additive effect of dabigatran and high-dose aspirin in the development of haemorrhagic pleural effusion in a patient with tuberculous pleuritis.
Topics: Aged; Antithrombins; Antitubercular Agents; Aspirin; Dabigatran; Humans; Male; Pleural Effusion; Ple | 2020 |
A case of aseptic pleuropericarditis in a patient with chronic plaque psoriasis under methotrexate therapy.
Topics: Anti-Inflammatory Agents; Aspirin; Chronic Disease; Colchicine; Dermatologic Agents; Drug Therapy, C | 2010 |
Lipoxin A4 inhibits acute edema in mice: implications for the anti-edematogenic mechanism induced by aspirin.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bradykinin; Carrageenan; D | 2006 |
Activation of plasma kallikrein-kinin system and its significant role in pleural fluid accumulation of rat carrageenin-induced pleurisy.
Topics: Animals; Aspirin; Bromelains; Captopril; Carrageenan; Kininogens; Kinins; Male; Molecular Weight; Pl | 1983 |
Effects of protein deficiency on the metabolism of arachidonic acid by rat pleural polymorphonuclear leukocytes.
Topics: Animals; Arachidonic Acids; Aspirin; Carrageenan; Disease Models, Animal; Kidney Medulla; Lipoxygena | 1983 |
The anti-inflammatory mechanism of MK-447 in rat carrageenin-induced pleurisy.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Butylated Hydroxytoluene; Carrageenan; Gas Chromatograph | 1983 |
Pathway of onset, development, and decay of carrageenan pleurisy in the rat.
Topics: Animals; Aspirin; Carrageenan; Colchicine; Cyclooxygenase Inhibitors; Exudates and Transudates; Mono | 1982 |
Changes in the levels of prostaglandins and thromboxane and their roles in the accumulation of exudate in rat carrageenin-induced pleurisy--a profile analysis using gas chromatography-mass spectrometry.
Topics: Animals; Aspirin; Carrageenan; Gas Chromatography-Mass Spectrometry; Imidazoles; Male; Pleurisy; Pro | 1982 |
[Broncaspin in the therapy of pediatric diseases of the respiratory tract].
Topics: Age Factors; Anti-Bacterial Agents; Aspirin; Bronchitis; Bronchopneumonia; Child; Child, Preschool; | 1981 |
Changes of prostaglandin and thromboxane levels in pleural fluid of rat carrageenin-induced pleurisy.
Topics: Animals; Aspirin; Butylated Hydroxytoluene; Carrageenan; Disease Models, Animal; Imidazoles; Inflamm | 1980 |
Induction of prostaglandin H synthase-2 in rat carrageenin-induced pleurisy and effect of a selective COX-2 inhibitor.
Topics: Animals; Aspirin; Carrageenan; Cyclooxygenase Inhibitors; Dexamethasone; Enzyme Induction; Isoenzyme | 1995 |
Increased migration of neutrophils to granulocyte-colony stimulating factor in rat carrageenin-induced pleurisy: roles of complement, bradykinin, and inducible cyclooxygenase-2.
Topics: Animals; Aspirin; Bradykinin; Capillary Permeability; Carrageenan; Cell Movement; Complement System | 1996 |
Involvement of prostaglandins in the down-regulation of allergic plasma leakage observed in rats undergoing pleural eosinophilia.
Topics: Animals; Aspirin; Dinoprostone; Down-Regulation; Eosinophils; Female; Hypersensitivity; Indomethacin | 1996 |
Differing profiles of prostaglandin formation inhibition between selective prostaglandin H synthase-2 inhibitors and conventional NSAIDs in inflammatory and non-inflammatory sites of the rat.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygen | 1998 |
Differential effects of inhibitors of cyclooxygenase (cyclooxygenase 1 and cyclooxygenase 2) in acute inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclo | 1998 |
Cutting edge: lipoxin (LX) A4 and aspirin-triggered 15-epi-LXA4 block allergen-induced eosinophil trafficking.
Topics: Allergens; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Mig | 2000 |
[Post-cardiac aggression syndrome: a case report].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diagnosis, Differential; Female; Follow-Up | 2000 |
Some effects of non-steroidal anti-inflammatory drugs on leucocyte migration.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Cell Movement; Edema; Fenoprofen; Ibuprofen | 1976 |
[New findings on the efficacy and mode of action of the horse chestnut saponin escin].
Topics: Animals; Aspirin; Bradykinin; Dose-Response Relationship, Drug; Escin; Exudates and Transudates; Fem | 1976 |
Quantitative comparison of the analgesic and anti-inflammatory activities of aspirin, phenacetin and acetaminophen in rodents.
Topics: Acetaminophen; Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Carragee | 1976 |
Effects of some non-steroidal anti-inflammatory drug copper complexes on polymorphonuclear leukocyte oxidative metabolism.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Copper; Free Radical Scavengers; In Vitro | 1990 |
Non-steroidal anti-inflammatory drug-copper complex modulation of polymorphonuclear leukocyte migration.
Topics: Acetates; Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Movement; Che | 1990 |
Modulation of the IL-1 content by anti-inflammatory drugs during an acute non-specific inflammation.
Topics: Animals; Aspirin; Calcium Pyrophosphate; Dexamethasone; Diclofenac; Interleukin-1; Male; Mice; Mice, | 1989 |
Antiinflammatory action of salicylates: aspirin is not a prodrug for salicylate against rat carrageenin pleurisy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Cell Count; Carrageenan; Gas Chroma | 1989 |
Non-steroidal anti-inflammatory drugs and leucocyte emigration.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cell Movement; Dextrans; Flufenamic Acid; Indomethacin; | 1972 |
Rheumatoid laryngitis.
Topics: Aged; Aspirin; Humans; Hypothyroidism; Iodine Radioisotopes; Laryngitis; Male; Pleurisy; Prednisolon | 1973 |
Haemolytic-uraemic syndrome in an adult with pericarditis and pleurisy.
Topics: Adult; Alopecia; Anemia, Hemolytic; Aspirin; Dipyridamole; Female; Hemolytic-Uremic Syndrome; Hepari | 1973 |
Some quantitative temporal characteristics of carrageenin-induced pleurisy in the rat.
Topics: Animals; Aspirin; Carrageenan; Cyproheptadine; Edema; Exudates and Transudates; Injections; Leukocyt | 1973 |
Rheumatoid arthritis associated with eosinophilia.
Topics: Aged; Antibodies, Anti-Idiotypic; Arthritis, Rheumatoid; Aspirin; Complement System Proteins; Eosino | 1971 |
Structure-activity relationships among some antiinflammatory 3-(5-aryl-2-tetrazolyl)alkanoic acids and derivatives.
Topics: Acetates; Administration, Oral; Amides; Animals; Anti-Inflammatory Agents; Aspirin; Azoles; Carragee | 1972 |
A histopathological and pharmacological analysis of the mode of action of nonsteroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Bone Marrow; Carrageenan; Edema; Indomethacin; Leukocyte | 1971 |
[Clinical-experimental study of lysine acetylsalicylate].
Topics: Adolescent; Adult; Aged; Aspirin; Blood Coagulation; Bone Neoplasms; Female; Fever; Fractures, Bone; | 1971 |
Pleurisy and fibrosis of the pleura during methysergide treatment of hemicrania.
Topics: Adult; Aspirin; Codeine; Diazepam; Ergotamine; Female; Functional Laterality; Humans; Male; Methyser | 1970 |