Page last updated: 2024-10-23

aspirin and Peripheral Nerve Injury

aspirin has been researched along with Peripheral Nerve Injury in 4 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
"Chronic inflammation was detected in intact uninjured old nerves, characterized by increased macrophage infiltration and raised levels of monocyte chemoattractant protein 1 (MCP1) and CC chemokine ligand 11 (CCL11)."1.48Inflammaging impairs peripheral nerve maintenance and regeneration. ( Akula, AK; Baader, SL; Bauer, R; Büttner, R; Carlstedt, A; Mindos, T; Morrison, H; Reuter, M; Riecken, LB; Schulz, A, 2018)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yogeeswari, P1
Ragavendran, JV1
Sriram, D1
Nageswari, Y1
Kavya, R1
Sreevatsan, N1
Vanitha, K1
Stables, J1
Büttner, R1
Schulz, A1
Reuter, M1
Akula, AK1
Mindos, T1
Carlstedt, A1
Riecken, LB1
Baader, SL1
Bauer, R1
Morrison, H1
Mohammadi, R1
Amini, K1
Abdollahi-Pirbazari, M1
Yousefi, A1
Chechik, O1
Goldstein, Y1
Behrbalk, E1
Kaufman, E1
Rabinovich, Y1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective, Nonrandomized, Study Comparing the Use of Aspirin and Intraoperative Blood Loss and Postoperative Complications Following Open Inguinal Hernia Repair.[NCT02084615]300 participants (Anticipated)Interventional2014-08-31Enrolling by invitation
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

4 other studies available for aspirin and Peripheral Nerve Injury

ArticleYear
Discovery of 4-aminobutyric acid derivatives possessing anticonvulsant and antinociceptive activities: a hybrid pharmacophore approach.
    Journal of medicinal chemistry, 2007, May-17, Volume: 50, Issue:10

    Topics: Analgesics; Animals; Anticonvulsants; Disease Models, Animal; gamma-Aminobutyric Acid; Hyperalgesia;

2007
Inflammaging impairs peripheral nerve maintenance and regeneration.
    Aging cell, 2018, Volume: 17, Issue:6

    Topics: Aging; Animals; Anti-Inflammatory Agents; Aspirin; Chemokine CCL11; Ganglia, Spinal; Inflammation; M

2018
Acetyl salicylic acid locally enhances functional recovery after sciatic nerve transection in rat.
    Neurologia medico-chirurgica, 2013, Volume: 53, Issue:12

    Topics: Administration, Topical; Animals; Aspirin; Axotomy; Drug Evaluation, Preclinical; Guided Tissue Rege

2013
Blood loss and complications following carotid endarterectomy in patients treated with clopidogrel.
    Vascular, 2012, Volume: 20, Issue:4

    Topics: Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Carotid Artery Diseases; Clopidogrel; Drug T

2012