aspirin has been researched along with Periodontitis in 31 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Periodontitis: Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We isolated extracellular vesicles (EVs) from periodontal stem cells (PDLSCs) and loaded with aspirin by sonication, and then evaluated the treatment efficacy of aspirin-loaded vesicles (EVs-ASP) in periodontitis model in mice." | 8.31 | Aspirin loaded extracellular vesicles inhibit inflammation of macrophages via switching metabolic phenotype in periodontitis. ( Da, N; He, X; Li, B; Shi, Y; Wang, Y; Yang, J; Zhang, R, 2023) |
| " We examined the effect of clopidogrel and aspirin on MSCs following induction of periodontitis in rats by placement of ligatures." | 7.81 | Clopidogrel Enhances Mesenchymal Stem Cell Proliferation Following Periodontitis. ( Albiero, ML; Alsadun, S; Coimbra, LS; Graves, DT; Pignolo, RJ; Rossa, C; Spolidorio, LC; Steffens, JP, 2015) |
| "To explore the optimal platelet aggregation rates (PAgTs) of aspirin users, which can ensure normal intra-socket clotting after extraction of a maxillary tooth with serious periodontitis, and to determine the reasonable time of pre-extraction aspirin suspension." | 7.80 | [Correlation between platelet aggregation rates of aspirin users and intra-socket clotting after extraction of a maxillary tooth with periodontitis]. ( Gao, YM; Lu, MM; Zhuang, XH, 2014) |
| " One such approach is the use of omega-3 polyunsaturated fatty acids (PUFAs) in combination with low-dose aspirin." | 7.01 | Adjunctive use of omega-3 fatty acids in combination with low-dose aspirin in periodontitis: Systematic review and meta-analysis. ( Kriventsov, MA; Neprelyuk, OA; Romanenko, IG; Zhad'ko, SI, 2023) |
| "Periodontitis is a common chronic inflammatory disease caused by bacteria which can result in periodontal tissue inflammation, as well as alveolar bone resorption." | 5.51 | Effects of omega-3 fatty acids and aspirin on Porphyromonas gingivalis-induced periodontitis in rats. ( Heo, SM; Li, L; Soh, Y; Yang, M, 2019) |
| "Fifty-five adults with moderate-to-severe periodontitis were enrolled in a randomized, 3-month double-masked, placebo-controlled trial of daily 2 g DHA or placebo capsules enriched with 81 mg aspirin; 46 enrollees completed the trial." | 5.24 | Impact of Docosahexaenoic Acid Therapy on Subgingival Plaque Microbiota. ( Goodson, JM; Hasturk, H; Mu, L; Mukamal, KJ; Naqvi, AZ; Van Dyke, TE, 2017) |
| " In this review, we discuss the possible repurposing of drugs approved for cardiovascular diseases, such as β-blockers, angiotensin converting enzyme inhibitors (ACE-Is), angiotensin II receptor blockers (ARBs), statins, aspirin, cardiac glycosides and low-molecular-weight heparins (LMWHs)." | 5.05 | Repurposing of drugs approved for cardiovascular diseases: Opportunity or mirage? ( Camera, M; Castiglioni, L; Gelosa, P; Sironi, L, 2020) |
| "We isolated extracellular vesicles (EVs) from periodontal stem cells (PDLSCs) and loaded with aspirin by sonication, and then evaluated the treatment efficacy of aspirin-loaded vesicles (EVs-ASP) in periodontitis model in mice." | 4.31 | Aspirin loaded extracellular vesicles inhibit inflammation of macrophages via switching metabolic phenotype in periodontitis. ( Da, N; He, X; Li, B; Shi, Y; Wang, Y; Yang, J; Zhang, R, 2023) |
| "Low-dose aspirin has been hypothesized as being a potential host modulatory agent for periodontitis treatment." | 3.81 | Association between low-dose aspirin and periodontal disease: results from the continuous national health and nutrition examination survey (NHANES) 2011-2012. ( Demmer, RT; Ioannou, AL; Kotsakis, GA; Michalowicz, BS; Thai, A, 2015) |
| " We examined the effect of clopidogrel and aspirin on MSCs following induction of periodontitis in rats by placement of ligatures." | 3.81 | Clopidogrel Enhances Mesenchymal Stem Cell Proliferation Following Periodontitis. ( Albiero, ML; Alsadun, S; Coimbra, LS; Graves, DT; Pignolo, RJ; Rossa, C; Spolidorio, LC; Steffens, JP, 2015) |
| "Clopidogrel but not aspirin showed the ability of preventing bone loss in experimental periodontitis." | 3.80 | Antiplatelet drugs reduce the immunoinflammatory response in a rat model of periodontal disease. ( Coimbra, LS; Muscará, MN; Rossa, C; Spolidorio, LC; Steffens, JP, 2014) |
| " Ligatures were removed after 10 days of periodontitis induction and all groups were submitted to treatment with aspirin (Asp) (30 mg/kg), clopidogrel (Clop) (75 mg/kg) or NaCl 0." | 3.80 | Clopidogrel enhances periodontal repair in rats through decreased inflammation. ( Coimbra, LS; Graves, DT; Rossa, C; Spolidorio, LC; Steffens, JP, 2014) |
| "To explore the optimal platelet aggregation rates (PAgTs) of aspirin users, which can ensure normal intra-socket clotting after extraction of a maxillary tooth with serious periodontitis, and to determine the reasonable time of pre-extraction aspirin suspension." | 3.80 | [Correlation between platelet aggregation rates of aspirin users and intra-socket clotting after extraction of a maxillary tooth with periodontitis]. ( Gao, YM; Lu, MM; Zhuang, XH, 2014) |
| "To measure the effects on periodontitis, ligatures were placed around first molars, and aspirin (Asp, 30 mg/kg) or clopidogrel (Clo, 75 mg/kg) was given intragastrically once daily for 15 days." | 3.77 | Influence of antiplatelet drugs in the pathogenesis of experimental periodontitis and periodontal repair in rats. ( Coimbra, LS; Gerlach, RF; Guimarães, MR; Herrera, BS; Muscará, MN; Rossa, C; Spolidorio, DM; Spolidorio, LC, 2011) |
| "Periodontitis is the sixth most prevalent chronic disease globally and places significant burdens on societies and economies worldwide." | 3.01 | The role of non-steroidal anti-inflammatory drugs as adjuncts to periodontal treatment and in periodontal regeneration. ( Fok, MR; Han, B; Lin, Y; Ren, J; Zhang, Y, 2023) |
| " One such approach is the use of omega-3 polyunsaturated fatty acids (PUFAs) in combination with low-dose aspirin." | 3.01 | Adjunctive use of omega-3 fatty acids in combination with low-dose aspirin in periodontitis: Systematic review and meta-analysis. ( Kriventsov, MA; Neprelyuk, OA; Romanenko, IG; Zhad'ko, SI, 2023) |
| "Periodontitis is a common chronic inflammatory disease initiated by bacteria, resulting in bone resorption, tooth loss, and systemic inflammation." | 2.79 | Docosahexaenoic Acid and Periodontitis in Adults: A Randomized Controlled Trial. ( Campos, H; Davis, RB; Goodson, JM; Halem, S; Hasturk, H; Mu, L; Mukamal, KJ; Naqvi, AZ; Phillips, RS; Van Dyke, TE, 2014) |
| "Periodontitis is a common chronic inflammatory disease caused by bacteria which can result in periodontal tissue inflammation, as well as alveolar bone resorption." | 1.51 | Effects of omega-3 fatty acids and aspirin on Porphyromonas gingivalis-induced periodontitis in rats. ( Heo, SM; Li, L; Soh, Y; Yang, M, 2019) |
| "Periodontitis is a local inflammatory environment with dysregulation of host responses, which results in destruction of periodontal tissues." | 1.48 | Therapeutic effect of bone marrow mesenchymal stem cells pretreated with acetylsalicylic acid on experimental periodontitis in rats. ( Chen, C; Chen, X; Li, L; Xiong, Y; Zhang, Y; Zhu, Z, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (12.90) | 18.7374 |
| 1990's | 2 (6.45) | 18.2507 |
| 2000's | 6 (19.35) | 29.6817 |
| 2010's | 13 (41.94) | 24.3611 |
| 2020's | 6 (19.35) | 2.80 |
| Authors | Studies |
|---|---|
| Ren, J | 1 |
| Fok, MR | 1 |
| Zhang, Y | 2 |
| Han, B | 1 |
| Lin, Y | 1 |
| Shi, Y | 1 |
| Zhang, R | 1 |
| Da, N | 1 |
| Wang, Y | 1 |
| Yang, J | 1 |
| Li, B | 1 |
| He, X | 1 |
| Neprelyuk, OA | 1 |
| Zhad'ko, SI | 1 |
| Romanenko, IG | 1 |
| Kriventsov, MA | 1 |
| Hasan, F | 1 |
| Ikram, R | 1 |
| Simjee, SU | 1 |
| Iftakhar, K | 1 |
| Asadullah, K | 1 |
| Usman, M | 1 |
| Hromcik, F | 1 |
| Vokurka, J | 1 |
| Gopfert, E | 1 |
| Faldyna, M | 1 |
| Hermanova, M | 1 |
| Kyr, M | 1 |
| Vicenova, M | 1 |
| Izakovicova Holla, L | 1 |
| Gelosa, P | 1 |
| Castiglioni, L | 1 |
| Camera, M | 1 |
| Sironi, L | 1 |
| Corbella, S | 1 |
| Calciolari, E | 1 |
| Alberti, A | 1 |
| Donos, N | 1 |
| Francetti, L | 1 |
| Naqvi, AZ | 2 |
| Mu, L | 2 |
| Hasturk, H | 2 |
| Van Dyke, TE | 4 |
| Mukamal, KJ | 2 |
| Goodson, JM | 2 |
| Xiong, Y | 1 |
| Chen, X | 1 |
| Chen, C | 1 |
| Zhu, Z | 1 |
| Li, L | 2 |
| Yang, M | 1 |
| Soh, Y | 1 |
| Heo, SM | 1 |
| Coimbra, LS | 4 |
| Steffens, JP | 3 |
| Muscará, MN | 2 |
| Rossa, C | 4 |
| Spolidorio, LC | 4 |
| Graves, DT | 2 |
| Phillips, RS | 1 |
| Davis, RB | 1 |
| Halem, S | 1 |
| Campos, H | 1 |
| Lu, MM | 1 |
| Zhuang, XH | 1 |
| Gao, YM | 1 |
| Kotsakis, GA | 1 |
| Thai, A | 1 |
| Ioannou, AL | 1 |
| Demmer, RT | 1 |
| Michalowicz, BS | 1 |
| Alsadun, S | 1 |
| Albiero, ML | 1 |
| Pignolo, RJ | 1 |
| Schonfeld, SE | 1 |
| Guimarães, MR | 1 |
| Gerlach, RF | 1 |
| Spolidorio, DM | 1 |
| Herrera, BS | 1 |
| Funosas, E | 1 |
| Feser, G | 1 |
| Escovich, L | 1 |
| Maestri, L | 1 |
| Serhan, CN | 1 |
| Romano, M | 1 |
| Elad, S | 1 |
| Chackartchi, T | 1 |
| Shapira, L | 1 |
| Findler, M | 1 |
| Flemmig, TF | 2 |
| Epp, B | 1 |
| Funkenhauser, Z | 1 |
| Newman, MG | 1 |
| Kornman, KS | 1 |
| Haubitz, I | 1 |
| Klaiber, B | 2 |
| Rumetsch, M | 1 |
| Howell, TH | 1 |
| Ridker, PM | 1 |
| Ajani, UA | 1 |
| Hennekens, CH | 1 |
| Christen, WG | 1 |
| Reiff, RL | 2 |
| White, CL | 2 |
| el Attar, T | 1 |
| Deines, DN | 1 |
| Overman, P | 1 |
| ElAttar, T | 1 |
| Platt, RD | 1 |
| Weyna, E | 1 |
| Banach, J | 1 |
| Malinowski, J | 1 |
| Spychalska, M | 1 |
| Zielińska, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficiency of Flurbiprofen 2.5% in Comparison to 98% Aloe Vera Gel as an Adjunctive Therapy to Scaling and Root Planning in the Initial Treatment of Stage III Chronic Periodontitis in Smoking Patients[NCT06041178] | Phase 4 | 60 participants (Actual) | Interventional | 2022-09-30 | Completed | ||
| The Effects of Docosahexaenoic Acid on Periodontitis in Adults: A Pilot Randomized Controlled Trial[NCT01976806] | Phase 2 | 55 participants (Actual) | Interventional | 2009-06-30 | Completed | ||
| Is Dietary Melatonin Supplementation a Viable Adjunctive Therapy for Chronic Periodontitis? A Preliminary Randomized Clinical Trial.[NCT03368430] | Phase 4 | 74 participants (Actual) | Interventional | 2016-07-04 | Completed | ||
| [NCT00000500] | Phase 3 | 0 participants | Interventional | 1981-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Gingival Index (GI) is a measure of gingival inflammation, which is assigned a score (0-3).~Score Criteria:~0: No inflammation.~Mild inflammation, slight change in color, slight edema, no bleeding on probing.~Moderate inflammation, moderate glazing, redness, bleeding on probing.~Severe inflammation, marked redness and hypertrophy, ulceration, tendency to spontaneous bleeding." (NCT01976806)
Timeframe: Baseline and 3 months
| Intervention | GI units (Mean) |
|---|---|
| Aspirin & Docosahexaenoic Acid | -0.26 |
| Aspirin & Placebo | -0.07 |
"Plaque Index (PI) is a measure of gingival inflammation as induced by bacterial plaque deposition at and under the gum line.~Score Criteria:~0: No plaque~A film of plaque adhering to the free gingival margin and adjacent area of the tooth, which can not be seen with the naked eye. But only by using disclosing solution or by using probe.~Moderate accumulation of deposits within the gingival pocket, on the gingival margin and/ or adjacent tooth surface, which can be seen with the naked eye.~Abundance of soft matter within the gingival pocket and/or on the tooth and gingival margin." (NCT01976806)
Timeframe: Baseline and 3 months
| Intervention | Plaque index units (Mean) |
|---|---|
| Aspirin & Docosahexaenoic Acid | -0.10 |
| Aspirin & Placebo | 0.07 |
Pocket probing depth (PD) is the depth a dental probe can be inserted into a gingival pocket at a particular site (6 sites per tooth) measured in millimeters among teeth with PD greater than or equal to 5 mm (N=533 dental sites total). (NCT01976806)
Timeframe: Baseline and 3 months
| Intervention | mm (Mean) |
|---|---|
| Aspirin & Docosahexaenoic Acid | -0.71 |
| Aspirin & Placebo | -0.54 |
Red blood cell phospholipid fatty acids were measured at baseline and 3-month follow up as a measure of adherence. (NCT01976806)
Timeframe: Baseline and 3 months
| Intervention | % of total RBC FA (Mean) |
|---|---|
| Aspirin & Docosahexaenoic Acid | 2.723 |
| Aspirin & Placebo | -0.1776 |
Gingival crevicular fluid (GCF) is the fluid bathing the teeth under the gum line. GCF samples were analyzed for high sensitivity C-reactive protein as a measure of local gingival inflammation. (NCT01976806)
Timeframe: Baseline and 3 months
| Intervention | ng/mL (Mean) |
|---|---|
| Aspirin & Docosahexaenoic Acid | -7.3715 |
| Aspirin & Placebo | -3.1268 |
Gingival crevicular fluid (GCF) samples were analyzed for Interleukin-1 beta, which is a measure of local gingival inflammation. (NCT01976806)
Timeframe: Baseline and 3 months
| Intervention | pg/mL (Mean) |
|---|---|
| Aspirin & Docosahexaenoic Acid | 0.8775 |
| Aspirin & Placebo | 21.5816 |
Gingival crevicular fluid (GCF) samples were analyzed for Interleukin-6, which is a measure of local gingival inflammation. (NCT01976806)
Timeframe: Baseline and 3 months
| Intervention | pg/mL (Mean) |
|---|---|
| Aspirin & Docosahexaenoic Acid | 0.1422 |
| Aspirin & Placebo | -0.00226 |
Serum high-sensitivity C-reactive protein is a measure of systemic inflammation. (NCT01976806)
Timeframe: Baseline and 3 months
| Intervention | mg/L (Mean) |
|---|---|
| Aspirin & Docosahexaenoic Acid | -0.3695 |
| Aspirin & Placebo | 0.7114 |
Serum high-sensitivity interleukin-6 is a measure of systemic inflammation. (NCT01976806)
Timeframe: Baseline and 3 months
| Intervention | pg/mL (Mean) |
|---|---|
| Aspirin & Docosahexaenoic Acid | 0.3295 |
| Aspirin & Placebo | -0.0690 |
Serum soluble vascular cell adhesion molecule (VCAM) is a measure of systemic inflammation. (NCT01976806)
Timeframe: Baseline and 3 months
| Intervention | ng/mL (Mean) |
|---|---|
| Aspirin & Docosahexaenoic Acid | 4.8829 |
| Aspirin & Placebo | 27.9409 |
Bleeding On Probing (BOP) is a measure of gingival inflammation and tissue destruction, which describes whether or not bleeding at the dental pocket occurred following probing. (NCT01976806)
Timeframe: 3 months
| Intervention | Sites (Count of Units) |
|---|---|
| Aspirin & Docosahexaenoic Acid | 202 |
| Aspirin & Placebo | 227 |
Urine N-Terminal Telopeptides are a measure of systemic bone turnover. (NCT01976806)
Timeframe: Baseline and 3 months
| Intervention | nM BCE (Mean) |
|---|---|
| Aspirin & Docosahexaenoic Acid | 103.3333 |
| Aspirin & Placebo | 61.8421 |
7 reviews available for aspirin and Periodontitis
| Article | Year |
|---|---|
The role of non-steroidal anti-inflammatory drugs as adjuncts to periodontal treatment and in periodontal regeneration.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Inflammation; Periodontitis; Regeneration | 2023 |
Adjunctive use of omega-3 fatty acids in combination with low-dose aspirin in periodontitis: Systematic review and meta-analysis.
Topics: Adolescent; Aspirin; Fatty Acids, Omega-3; Humans; Immunologic Factors; Periodontal Index; Periodont | 2023 |
Repurposing of drugs approved for cardiovascular diseases: Opportunity or mirage?
Topics: Acute Kidney Injury; Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Angiotensin-Conv | 2020 |
Systematic review and meta-analysis on the adjunctive use of host immune modulators in non-surgical periodontal treatment in healthy and systemically compromised patients.
Topics: Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Chronic Disea | 2021 |
Resolution of inflammation: a new paradigm for the pathogenesis of periodontal diseases.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 15-Lipoxygenase; Aspirin; Humans; Hyd | 2003 |
Lipid mediators: lipoxin and aspirin-triggered 15-epi-lipoxins.
Topics: Acetylation; Animals; Anti-Inflammatory Agents; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxy | 2006 |
Control of inflammation and periodontitis.
Topics: Alveolar Bone Loss; Animals; Anti-Inflammatory Agents; Aspirin; Biofilms; Bone Regeneration; Disease | 2007 |
7 trials available for aspirin and Periodontitis
| Article | Year |
|---|---|
The effects of aspirin gel and mouthwash on levels of salivary biomarkers PGE2, TNF-α and nitric oxide in patients with periodontal diseases.
Topics: Adult; Anti-Inflammatory Agents; Aspirin; Biomarkers; Dinoprostone; Female; Gels; Gingivitis; Humans | 2019 |
Impact of Docosahexaenoic Acid Therapy on Subgingival Plaque Microbiota.
Topics: Adult; Aspirin; Dental Plaque; Docosahexaenoic Acids; Double-Blind Method; Female; Humans; Male; Mic | 2017 |
Docosahexaenoic Acid and Periodontitis in Adults: A Randomized Controlled Trial.
Topics: Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; C-Reactive Protei | 2014 |
Alteration of hemostasis in patients treated with subgingival NSAIDs during periodontal therapy.
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chronic Disease; G | 2012 |
Adjunctive supragingival irrigation with acetylsalicylic acid in periodontal supportive therapy.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemoprevention; Chemotherapy, Adjuva | 1995 |
Efficacy of systemically administered acetylsalicylic acid plus scaling on periodontal health and elastase-alpha 1-proteinase inhibitor in gingival crevicular fluid.
Topics: Administration, Oral; Adult; Aged; alpha 1-Antitrypsin; Analysis of Variance; Anti-Inflammatory Agen | 1996 |
Periodontal disease and risk of subsequent cardiovascular disease in U.S. male physicians.
Topics: Adult; Aged; Aspirin; Bacterial Infections; beta Carotene; Cause of Death; Coronary Disease; Double- | 2001 |
17 other studies available for aspirin and Periodontitis
| Article | Year |
|---|---|
Aspirin loaded extracellular vesicles inhibit inflammation of macrophages via switching metabolic phenotype in periodontitis.
Topics: Animals; Aspirin; Extracellular Vesicles; Inflammation; Lipopolysaccharides; Macrophages; Mice; Peri | 2023 |
Granulation tissue enriched by aspirin and omega-3 fatty acids in healing experimental periodontal lesion.
Topics: Animals; Aspirin; Fatty Acids, Omega-3; Granulation Tissue; Lipoxins; Periodontitis; Rabbits | 2021 |
Therapeutic effect of bone marrow mesenchymal stem cells pretreated with acetylsalicylic acid on experimental periodontitis in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bacteroidaceae Infections; Bone Marrow; B | 2018 |
Effects of omega-3 fatty acids and aspirin on Porphyromonas gingivalis-induced periodontitis in rats.
Topics: Alveolar Bone Loss; Animals; Aspirin; Fatty Acids, Omega-3; Interleukin-1beta; Male; Periodontitis; | 2019 |
Antiplatelet drugs reduce the immunoinflammatory response in a rat model of periodontal disease.
Topics: Alveolar Bone Loss; Animals; Anti-Inflammatory Agents; Aspirin; Clopidogrel; Collagen; Connective Ti | 2014 |
Clopidogrel enhances periodontal repair in rats through decreased inflammation.
Topics: Alveolar Bone Loss; Animals; Aspirin; Cell Count; Chemokine CCL5; Chemokine CXCL12; Clopidogrel; Inf | 2014 |
[Correlation between platelet aggregation rates of aspirin users and intra-socket clotting after extraction of a maxillary tooth with periodontitis].
Topics: Aspirin; Bicuspid; Humans; Molar; Periodontitis; Platelet Aggregation; Platelet Aggregation Inhibito | 2014 |
Association between low-dose aspirin and periodontal disease: results from the continuous national health and nutrition examination survey (NHANES) 2011-2012.
Topics: Adult; Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross-Sectional Studies; Diabe | 2015 |
Clopidogrel Enhances Mesenchymal Stem Cell Proliferation Following Periodontitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Movement; Cell Proliferation; Clopid | 2015 |
Strategies for managing periodontal inflammation.
Topics: Anti-Infective Agents, Local; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bone Density Conserv | 2010 |
Influence of antiplatelet drugs in the pathogenesis of experimental periodontitis and periodontal repair in rats.
Topics: Alveolar Bone Loss; Animals; Aspirin; Blood Platelets; Bone Density; Bone Regeneration; Clopidogrel; | 2011 |
A critically severe gingival bleeding following non-surgical periodontal treatment in patients medicated with anti-platelet.
Topics: Aspirin; Clopidogrel; Drug Combinations; Female; Gingival Hemorrhage; Humans; Middle Aged; Periodont | 2008 |
Study suggests aspirin can help fight periodontitis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Australia; Humans; Male; Periodontitis; Prostaglan | 2000 |
Clinical evaluation of gingival inflammation following use of buffered aspirin and buffer-only oral rinses. Preliminary results.
Topics: Adult; Antacids; Aspirin; Buffers; Gingivitis; Humans; Mouthwashes; Periodontitis; Pilot Projects | 1988 |
Aspirin, buffered aspirin, and effervescent buffer rinses in reducing gingival inflammation in patients with gingivitis and early periodontitis.
Topics: Adult; Antacids; Aspirin; Buffers; Double-Blind Method; Female; Gingival Hemorrhage; Gingivitis; Hum | 1988 |
[Effect of topical action of Polopiryna S on the inflammatory conditions of periodontal tissues in clinical and cytological investigations].
Topics: Adolescent; Adult; Aspirin; Female; Gingivitis; Humans; Male; Middle Aged; Mouthwashes; Periodontiti | 1988 |
[Clinical evaluation of Appernyl preparation].
Topics: Adolescent; Adult; Aspirin; Child; Dry Socket; Evaluation Studies as Topic; Humans; Periodontitis; S | 1973 |