aspirin has been researched along with Peptic Ulcer Perforation in 30 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Peptic Ulcer Perforation: Penetration of a PEPTIC ULCER through the wall of DUODENUM or STOMACH allowing the leakage of luminal contents into the PERITONEAL CAVITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the incidence and mortality related to peptic ulcer perforation while considering the intake of low-dose aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs)." | 7.74 | Clinical trial: the incidence and early mortality after peptic ulcer perforation, and the use of low-dose aspirin and nonsteroidal anti-inflammatory drugs. ( Angerson, WJ; Gilmour, D; McCloskey, C; Morran, CG; Prasad, R; Taha, AS, 2008) |
| "Current studies lack appropriate data on aspirin and other risk factors for gastrointestinal perforation." | 7.69 | Evidence of aspirin use in both upper and lower gastrointestinal perforation. ( Bajador, E; Benito, R; Esteva, F; Lanas, A; Sáinz, R; Serrano, P, 1997) |
| "To evaluate the incidence and mortality related to peptic ulcer perforation while considering the intake of low-dose aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs)." | 3.74 | Clinical trial: the incidence and early mortality after peptic ulcer perforation, and the use of low-dose aspirin and nonsteroidal anti-inflammatory drugs. ( Angerson, WJ; Gilmour, D; McCloskey, C; Morran, CG; Prasad, R; Taha, AS, 2008) |
| "Current studies lack appropriate data on aspirin and other risk factors for gastrointestinal perforation." | 3.69 | Evidence of aspirin use in both upper and lower gastrointestinal perforation. ( Bajador, E; Benito, R; Esteva, F; Lanas, A; Sáinz, R; Serrano, P, 1997) |
| "The gastric ulcer is easily detected by a barium meal study although a barium enema may be necessary to show the fistulous communication." | 1.26 | Gastrocolic fistula as a complication of benign gastric ulcer. ( Laufer, I; Stolberg, H; Thornley, GD, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (76.67) | 18.7374 |
| 1990's | 1 (3.33) | 18.2507 |
| 2000's | 6 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Taha, AS | 1 |
| Angerson, WJ | 1 |
| Prasad, R | 1 |
| McCloskey, C | 1 |
| Gilmour, D | 1 |
| Morran, CG | 1 |
| Hermansson, M | 1 |
| Ekedahl, A | 1 |
| Ranstam, J | 1 |
| Zilling, T | 1 |
| Reed, S | 1 |
| PLEWINSKI, G | 1 |
| WANKA, J | 1 |
| JONES, LI | 1 |
| WOOD, PH | 1 |
| DIXON, AS | 1 |
| Lanas, A | 2 |
| García Rodríguez, LA | 1 |
| Barreales Tolosa, L | 1 |
| Berndt, H | 1 |
| Serrano, P | 1 |
| Bajador, E | 1 |
| Esteva, F | 1 |
| Benito, R | 1 |
| Sáinz, R | 1 |
| Jost, JL | 1 |
| Vayre, P | 1 |
| Hureau, J | 1 |
| Benit, C | 1 |
| Takeuchi, K | 1 |
| Okabe, S | 1 |
| Takagi, K | 1 |
| Umeda, N | 1 |
| Barkin, JS | 1 |
| Langman, MJ | 2 |
| Tysiachnova, OV | 1 |
| Brown, RC | 1 |
| Lambert, PM | 1 |
| Laufer, I | 1 |
| Thornley, GD | 1 |
| Stolberg, H | 1 |
| Hazleman, BL | 1 |
| Florent, C | 1 |
| Desaint, B | 1 |
| Henry, DA | 1 |
| Johnston, A | 1 |
| Dobson, A | 1 |
| Duggan, J | 1 |
| Kolbasa, KP | 1 |
| Lancaster, C | 1 |
| Olafsson, AS | 1 |
| Gilbertson, SK | 1 |
| Robert, A | 1 |
| Matthewson, K | 1 |
| Pugh, S | 1 |
| Northfield, TC | 1 |
| Christensen, LA | 1 |
| Schmidt, EB | 1 |
| Levrat, M | 1 |
| Bock, OA | 1 |
| Grabowski, T | 1 |
| Duggan, JM | 2 |
| Hugh, TB | 1 |
| Donnellan, M | 1 |
| Fagan, PA | 1 |
3 reviews available for aspirin and Peptic Ulcer Perforation
| Article | Year |
|---|---|
Gastrointestinal injury from NSAID therapy. How to reduce the risk of complications.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; Dyspepsia; Gastrointest | 2005 |
Incidence of gastropathy in destructive arthropathies.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Esophagus; Female; Gastrointestinal H | 1989 |
[Modern views on peptic ulcers].
Topics: Alcohols; Aspirin; Duodenal Ulcer; Female; Gastric Mucosa; Gastrins; Humans; Male; Parasympatholytic | 1970 |
27 other studies available for aspirin and Peptic Ulcer Perforation
| Article | Year |
|---|---|
Clinical trial: the incidence and early mortality after peptic ulcer perforation, and the use of low-dose aspirin and nonsteroidal anti-inflammatory drugs.
Topics: Adolescent; Adult; Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Comorbidity; | 2008 |
Decreasing incidence of peptic ulcer complications after the introduction of the proton pump inhibitors, a study of the Swedish population from 1974-2002.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Dose-Response Relationshi | 2009 |
Nonsteroidal anti-inflammatory drug-induced duodenal ulceration and perforation in a mature rottweiler.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dog Diseases; Dogs; Duodenal Ulcer; Male; | 2002 |
[PERFORATED GASTRIC ULCER AS A COMPLICATION OF ACTH AND ASPIRIN THERAPY].
Topics: Adrenocorticotropic Hormone; Aspirin; Humans; Optic Neuritis; Peptic Ulcer Perforation; Stomach Ulce | 1963 |
INDOMETHACIN IN RHEUMATIC DISEASES. A CONTROLLED CLINICAL TRIAL.
Topics: Arthritis; Arthritis, Rheumatoid; Aspirin; Biomedical Research; Drug Hypersensitivity; Gastrointesti | 1964 |
Risk of upper gastrointestinal complications among users of traditional NSAIDs and COXIBs in the general population.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Anticoagulants; Aspirin; Case-Control St | 2007 |
[Pathogen eradication prevents gastrointestinal complications].
Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspi | 2007 |
[Drug-induced hemorrhages of the gastrointestinal tract].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Anticoagulants; Aspirin; Ethacrynic Acid; Gastrit | 1983 |
Evidence of aspirin use in both upper and lower gastrointestinal perforation.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Helicobacter Infections; Helicobacte | 1997 |
[Massive pneumoperitoneum as a sequela to rupture of a gastric ulcer and ventilatory resuscitation under pressure].
Topics: Aspirin; Drowning; Female; Humans; Middle Aged; Oxygen Inhalation Therapy; Peptic Ulcer Perforation; | 1978 |
Influence of aspirin on healing of chronic gastric ulcers in dogs.
Topics: Acetates; Animals; Aspirin; Chronic Disease; Dogs; Gastric Mucosa; Gastroscopy; Male; Peptic Ulcer P | 1977 |
Intractable peptic ulcer disease.
Topics: Aspirin; Chronic Disease; Humans; Hypercalcemia; Hyperparathyroidism; Peptic Ulcer; Peptic Ulcer Per | 1976 |
Gastric ulcer: natural history and treatment.
Topics: Adult; Aspirin; Australia; Boston; Carbenoxolone; Female; Gastrointestinal Hemorrhage; Glycyrrhiza; | 1976 |
[Case of multiple performation of intestinal ulcers during treatment with prednisolone, aspirin and potassium chloride ].
Topics: Adolescent; Aspirin; Humans; Ileum; Male; Peptic Ulcer; Peptic Ulcer Perforation; Potassium Chloride | 1975 |
Hospital admissions for peptic ulcer during 1958-72.
Topics: Adolescent; Adult; Age Factors; Aged; Aspirin; Female; Hospitalization; Humans; Male; Middle Aged; P | 1976 |
Gastrocolic fistula as a complication of benign gastric ulcer.
Topics: Adult; Aged; Aspirin; Barium Sulfate; Colonic Diseases; Colonic Neoplasms; Diagnosis, Differential; | 1976 |
[Frequency and severity of gastric and duodenal lesions induced by non-steroidal anti-inflammatory agents and aspirin].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; France; Humans; Male; Peptic Ulcer; Peptic | 1989 |
Ulcer perforation in the elderly and non-steroidal anti-inflammatory drugs.
Topics: Aged; Anti-Inflammatory Agents; Aspirin; Humans; Middle Aged; Peptic Ulcer; Peptic Ulcer Perforation | 1986 |
Fatal peptic ulcer complications and the use of non-steroidal anti-inflammatory drugs, aspirin, and corticosteroids.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; A | 1987 |
Indomethacin-induced gastric antral ulcers in hamsters.
Topics: Administration, Oral; Animals; Aspirin; Cimetidine; Cricetinae; Dinoprostone; Disease Models, Animal | 1988 |
Which peptic ulcer patients bleed?
Topics: Adult; Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Humans; Male; Mi | 1988 |
Perforated peptic ulcer--a complication in acute salicylate intoxication.
Topics: Acute Disease; Acute Kidney Injury; Aspirin; Cimetidine; Female; Humans; Middle Aged; Peptic Ulcer P | 1987 |
[Nosologic borderlines of gastroduodenal ulcerous disease].
Topics: Aspirin; Diagnosis, Differential; Gastritis; Gastrointestinal Hemorrhage; Humans; Peptic Ulcer; Pept | 1972 |
The management of a patient with a duodenal ulcer.
Topics: Adult; Alcohol Drinking; Alkalies; Aspirin; Chronic Disease; Diet Therapy; Duodenal Ulcer; Humans; P | 1972 |
Aspirin ingestion and perforated peptic ulcer.
Topics: Aspirin; Duodenal Ulcer; Female; Humans; Male; Peptic Ulcer Perforation; Sex Factors; Stomach Ulcer; | 1972 |
Perforated peptic ulcer.
Topics: Adult; Age Factors; Aspirin; Australia; Duodenal Ulcer; Female; Follow-Up Studies; Gastrectomy; Huma | 1969 |
The relationship between perforated peptic ulcer and aspirin ingestion.
Topics: Aged; Aspirin; Duodenal Ulcer; Dyspepsia; Female; Humans; Male; Middle Aged; Peptic Ulcer Perforatio | 1965 |