aspirin has been researched along with Patency of the Ductus Arteriosus in 26 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In patients with patent foramen ovale (PFO) and stroke or transient ischemic attack, we recommend initial aspirin therapy (Grade 1B) and suggest substitution of VKA if recurrence (Grade 2C)." | 3.78 | Antithrombotic and thrombolytic therapy for valvular disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. ( Fremes, SE; Rubens, FD; Sun, JC; Teoh, KH; Whitlock, RP, 2012) |
| " Observations collected in two population pharmacokinetic studies, in preterm neonates, investigating amikacin and vancomycin were used to estimate: i) the impact of ibuprofen administration on the clearance of these drugs; and ii) the difference between prophylactic and therapeutic administration of ibuprofen on this clearance." | 2.72 | Impact of ibuprofen administration on renal drug clearance in the first weeks of life. ( Allegaert, K; Anderson, BJ; Rayyan, M, 2006) |
| "Aspirin (ASA) is an alternative, but there are no controlled trials on its efficacy." | 2.68 | Aspirin versus indomethacin treatment of patent ductus arteriosus in preterm infants with respiratory distress syndrome. ( Brus, F; Elzenga, NJ; Okken, A; Schasfoort, M; van Acker, KJ; van der Auwera, JC; van Overmeire, B, 1995) |
| "Aspirin treatment during pregnancy seemed to reduce the incidence of hs-PDA in preterm infant and to increase infant responsiveness to postnatal medical treatment of PDA." | 1.72 | Effects of maternal aspirin treatment on hemodynamically significant patent ductus arteriosus in preterm infants - pilot study. ( Beer, G; Fridman, E; Kapusta, L; Mandel, D; Mangel, L; Marom, R, 2022) |
| "Here is a case of a female with patent ductus arteriosus, who was apparently in quite good state of health and gave birth to six offsprings without herself having any problem." | 1.48 | Patent Ductus Arteriosus with Infective Vegetations in Grandmultipara. ( Siddiqa, A; Sohail, N, 2018) |
| "Indomethacin is used to close the patent ductus arteriosus in premature infants and for tocolysis of preterm labor." | 1.35 | Delayed neonatal closure of the ductus arteriosus following early in utero exposure to indomethacin in the rat. ( Imamura, S; Ito, K; Momma, K; Nakanishi, T; Sugiyama, K; Sun, F; Toyoshima, K, 2009) |
| " Patients with this renal disorder require a permanent high dosed indomethacin therapy." | 1.27 | [The significance of renal prostaglandins for kidney function in early childhood]. ( Seyberth, HW, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (73.08) | 18.7374 |
| 1990's | 1 (3.85) | 18.2507 |
| 2000's | 2 (7.69) | 29.6817 |
| 2010's | 3 (11.54) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Fridman, E | 1 |
| Mangel, L | 1 |
| Mandel, D | 1 |
| Beer, G | 1 |
| Kapusta, L | 1 |
| Marom, R | 1 |
| Siddiqa, A | 1 |
| Sohail, N | 1 |
| Kimura, M | 1 |
| Kanazawa, H | 1 |
| Kawamura, A | 1 |
| Yamamoto, T | 1 |
| Egashira, T | 1 |
| Kohno, T | 1 |
| Maekawa, Y | 1 |
| Sano, M | 1 |
| Fukuda, K | 1 |
| Momma, K | 1 |
| Toyoshima, K | 1 |
| Ito, K | 1 |
| Sugiyama, K | 1 |
| Imamura, S | 1 |
| Sun, F | 1 |
| Nakanishi, T | 1 |
| Whitlock, RP | 1 |
| Sun, JC | 1 |
| Fremes, SE | 1 |
| Rubens, FD | 1 |
| Teoh, KH | 1 |
| Allegaert, K | 1 |
| Rayyan, M | 1 |
| Anderson, BJ | 1 |
| Furst, DE | 1 |
| Niebyl, JR | 2 |
| Friedberg, DZ | 1 |
| Rajpal, RS | 1 |
| Litwin, SB | 1 |
| Zondlo, J | 1 |
| van Overmeire, B | 1 |
| Brus, F | 1 |
| van Acker, KJ | 1 |
| van der Auwera, JC | 1 |
| Schasfoort, M | 1 |
| Elzenga, NJ | 1 |
| Okken, A | 1 |
| Bartel, J | 1 |
| Dipalma, JR | 1 |
| Horwitz, DL | 1 |
| Rudolph, AM | 2 |
| Heymann, MA | 3 |
| Schrager, GO | 1 |
| Soós, J | 1 |
| Várkonyi, P | 1 |
| Hartyánszky, I | 1 |
| Szabolcs, J | 1 |
| Fekete-Farkas, P | 1 |
| Lozsádi, K | 1 |
| Hoffman, JI | 1 |
| Sharpe, GL | 1 |
| Altshuler, G | 1 |
| Lines, DR | 1 |
| Cooperman, EM | 1 |
| Silverman, NH | 1 |
| Sibai, BM | 1 |
| Mirro, R | 1 |
| Chesney, CM | 1 |
| Leffler, C | 1 |
| Witter, FR | 1 |
| Anker, R | 1 |
| Quezada, A | 1 |
| Seyberth, HW | 1 |
| Cunningham, MD | 1 |
| Ellison, RC | 1 |
| Zierler, S | 1 |
| Kanto, WP | 1 |
| Miettinen, OS | 1 |
| Nadas, AS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Liberal Versus Restrictive Platelet Transfusion for Treatment of Hemodynamically Significant Patent Ductus Arteriosus in Thrombocytopenic Preterm Neonates- A Randomized Open Label, Controlled Trial[NCT03022253] | Phase 3 | 44 participants (Anticipated) | Interventional | 2016-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for aspirin and Patency of the Ductus Arteriosus
| Article | Year |
|---|---|
Preterm parturition. Prostaglandin synthetase inhibitors.
Topics: Amniotic Fluid; Animals; Aspirin; Cyclooxygenase Inhibitors; Ductus Arteriosus; Ductus Arteriosus, P | 1981 |
[Drug therapy of patent ductus arteriosus in premature and newborn infants].
Topics: Apnea; Aspirin; Chloroquine; Digitalis Glycosides; Ductus Arteriosus, Patent; Humans; Indomethacin; | 1978 |
[Derivatives of arachidonic acid. II. Medical perspectives].
Topics: Aspirin; Dinoprostone; Ductus Arteriosus, Patent; Humans; Immunity, Cellular; Indomethacin; Leukocyt | 1986 |
4 trials available for aspirin and Patency of the Ductus Arteriosus
| Article | Year |
|---|---|
Impact of ibuprofen administration on renal drug clearance in the first weeks of life.
Topics: Age Factors; Amikacin; Anti-Bacterial Agents; Aspirin; Betamethasone; Birth Weight; Cyclooxygenase I | 2006 |
Aspirin versus indomethacin treatment of patent ductus arteriosus in preterm infants with respiratory distress syndrome.
Topics: Aspirin; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Logistic Models; Prospect | 1995 |
Low-dose aspirin in pregnancy.
Topics: Alprostadil; Apgar Score; Aspirin; Blood Platelets; Dose-Response Relationship, Drug; Ductus Arterio | 1989 |
Inhibition of arachidonic acid metabolism in the perinatal period: pharmacology, clinical application, and potential adverse effects.
Topics: Administration, Oral; Arachidonic Acid; Arachidonic Acids; Aspirin; Clinical Trials as Topic; Cycloo | 1986 |
19 other studies available for aspirin and Patency of the Ductus Arteriosus
| Article | Year |
|---|---|
Effects of maternal aspirin treatment on hemodynamically significant patent ductus arteriosus in preterm infants - pilot study.
Topics: Aspirin; Ductus Arteriosus, Patent; Humans; Ibuprofen; Infant; Infant, Newborn; Infant, Premature; P | 2022 |
Patent Ductus Arteriosus with Infective Vegetations in Grandmultipara.
Topics: Adult; Aspirin; Ductus Arteriosus, Patent; Echocardiography; Endocarditis, Bacterial; Female; Fever; | 2018 |
Simultaneous transcatheter closure of an atrial septal defect and patent ductus arteriosus in an adult case, followed by thrombocytopenia and subclinical hemolysis.
Topics: Aged; Aspirin; Cardiac Catheterization; Ductus Arteriosus, Patent; Female; Heart Septal Defects, Atr | 2016 |
Delayed neonatal closure of the ductus arteriosus following early in utero exposure to indomethacin in the rat.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibito | 2009 |
Antithrombotic and thrombolytic therapy for valvular disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.
Topics: Aspirin; Catheterization; Combined Modality Therapy; Ductus Arteriosus, Patent; Evidence-Based Medic | 2012 |
Use of ibuprofen in unusual circumstances.
Topics: Arthritis, Rheumatoid; Aspirin; Bartter Syndrome; Cyclooxygenase Inhibitors; Digoxin; Drug Hypersens | 1984 |
Persistent reactivity of patent ductus with a review of the mechanism of spontaneous closure.
Topics: Aspirin; Cardiac Catheterization; Child, Preschool; Ductus Arteriosus, Patent; Female; Heart Murmurs | 1981 |
Pharmacology of the ductus arteriosus.
Topics: Aspirin; Chloroquine; Cyclooxygenase Inhibitors; Ductus Arteriosus; Ductus Arteriosus, Patent; Femal | 1978 |
Aspirin: new uses for an old drug.
Topics: Aspirin; Bartter Syndrome; Diabetic Angiopathies; Ductus Arteriosus, Patent; Humans; Myocardial Infa | 1979 |
Medical treatment of the ductus arteriosus.
Topics: Animals; Aspirin; Coronary Circulation; Ductus Arteriosus; Ductus Arteriosus, Patent; Fetal Heart; F | 1977 |
PDAs, prostaglandins, and RLF.
Topics: Aspirin; Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Newborn; Pregnancy; Prosta | 1978 |
[Possibility of closure of the patent dutus arteriosus by drug therapy in the management of congenital defects in the newborn infant (preliminary report)].
Topics: Aspirin; Ductus Arteriosus, Patent; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male | 1978 |
Problem of patent ductus arteriosus in premature infants.
Topics: Animals; Aspirin; Blood Pressure; Coronary Circulation; Ductus Arteriosus, Patent; Heart Failure; He | 1978 |
Ductal manipulation--a note of caution.
Topics: Aspirin; Ductus Arteriosus; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Oxygen | 1977 |
Breakthrough in treatment of patent ductus arteriosus.
Topics: Aspirin; Chloroquine; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Prem | 1977 |
New uses for acetylsalicylic acid and other prostaglandin antagonists.
Topics: Aspirin; Crohn Disease; Ductus Arteriosus; Ductus Arteriosus, Patent; Female; Humans; Infant, Newbor | 1977 |
Closure of the ductus arteriosus in premature infants by inhibition of prostaglandin synthesis.
Topics: Aspirin; Depression, Chemical; Ductus Arteriosus; Ductus Arteriosus, Patent; Female; Follow-Up Studi | 1976 |
[The significance of renal prostaglandins for kidney function in early childhood].
Topics: Angiotensin II; Aspirin; Child, Preschool; Creatinine; Ductus Arteriosus, Patent; Glomerular Filtrat | 1987 |
Perinatal risk assessment for patent ductus arteriosus in premature infants.
Topics: Adolescent; Adult; Aspirin; Birth Weight; Ductus Arteriosus, Patent; Female; Histamine Antagonists; | 1986 |