aspirin has been researched along with Ovarian Hyperstimulation Syndrome in 11 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Ovarian Hyperstimulation Syndrome: A complication of OVULATION INDUCTION in infertility treatment. It is graded by the severity of symptoms which include OVARY enlargement, multiple OVARIAN FOLLICLES; OVARIAN CYSTS; ASCITES; and generalized EDEMA. The full-blown syndrome may lead to RENAL FAILURE, respiratory distress, and even DEATH. Increased capillary permeability is caused by the vasoactive substances, such as VASCULAR ENDOTHELIAL GROWTH FACTORS, secreted by the overly-stimulated OVARIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of the study was to compare the efficacy of letrozole, an aromatase inhibitor, with aspirin in primary prevention of early ovarian hyperstimulation syndrome and to compare vascular endothelial growth factor levels between groups." | 9.24 | Effect of letrozole on moderate and severe early-onset ovarian hyperstimulation syndrome in high-risk women: a prospective randomized trial. ( Hu, X; Huang, K; Luo, Y; Mai, Q; Yang, G; Yuan, Y; Zhou, C, 2017) |
| "To evaluate the effect of low-dose aspirin therapy on ovarian hyperstimulation syndrome (OHSS) in an unselected group of patients undergoing in vitro fertilization (IVF)." | 9.14 | Low-dose aspirin therapy to prevent ovarian hyperstimulation syndrome. ( Bódis, J; Busznyák, C; Koppán, M; Mánfai, Z; Várnagy, A; Wilhelm, F, 2010) |
| "The objective of the study was to compare the efficacy of letrozole, an aromatase inhibitor, with aspirin in primary prevention of early ovarian hyperstimulation syndrome and to compare vascular endothelial growth factor levels between groups." | 5.24 | Effect of letrozole on moderate and severe early-onset ovarian hyperstimulation syndrome in high-risk women: a prospective randomized trial. ( Hu, X; Huang, K; Luo, Y; Mai, Q; Yang, G; Yuan, Y; Zhou, C, 2017) |
| "To evaluate the effect of low-dose aspirin therapy on ovarian hyperstimulation syndrome (OHSS) in an unselected group of patients undergoing in vitro fertilization (IVF)." | 5.14 | Low-dose aspirin therapy to prevent ovarian hyperstimulation syndrome. ( Bódis, J; Busznyák, C; Koppán, M; Mánfai, Z; Várnagy, A; Wilhelm, F, 2010) |
| "To test whether adjuvant therapy with acetylsalicylic acid (ASA) and prednisolone (ASA+Pred) could improve the outcome of IVF in good-pregnancy prognosis patients." | 5.13 | Low-dose acetylsalicylic acid plus prednisolone as an adjuvant treatment in IVF: a prospective, randomized study. ( Dolfin, E; Gennarelli, G; Holte, JG; Lantieri, T; Massobrio, M; Revelli, A; Tur-Kaspa, I, 2008) |
| "Combining aspirin, cabergoline, and triggering with low dose of HCG in combination with GnRH agonist produced excellent clinical pregnancy rate, and decreased hospital admissions with severe or critical OHSS." | 3.85 | Combining several interventions to reduce the incidence of OHSS: A prospective cohort study. ( Abdelsalam, EA; Elmahdy, M; Maghraby, HA, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 6 (54.55) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Nagy, B | 1 |
| Sulyok, E | 1 |
| Várnagy, Á | 3 |
| Barabás, A | 1 |
| Kovács, K | 1 |
| Bódis, J | 4 |
| Elmahdy, M | 1 |
| Abdelsalam, EA | 1 |
| Maghraby, HA | 1 |
| Namavar Jahromi, B | 1 |
| Zolghadri, J | 1 |
| Rahmani, E | 1 |
| Alipour, S | 1 |
| Anvar, Z | 1 |
| Zarei, A | 1 |
| Keramati, P | 1 |
| Kumako, V | 1 |
| Derex, L | 1 |
| Blanc-Lasserre, K | 1 |
| Beschet, A | 1 |
| Benhamouda, H | 1 |
| Nighoghossian, N | 1 |
| Mai, Q | 1 |
| Hu, X | 1 |
| Yang, G | 1 |
| Luo, Y | 1 |
| Huang, K | 1 |
| Yuan, Y | 1 |
| Zhou, C | 1 |
| Nelson, SM | 1 |
| Mánfai, Z | 2 |
| Wilhelm, F | 1 |
| Busznyák, C | 2 |
| Koppán, M | 2 |
| Vladimirov, IaK | 1 |
| Revelli, A | 1 |
| Dolfin, E | 1 |
| Gennarelli, G | 1 |
| Lantieri, T | 1 |
| Massobrio, M | 1 |
| Holte, JG | 1 |
| Tur-Kaspa, I | 1 |
| Tinneberg, HR | 1 |
| Hanf, V | 1 |
| Török, A | 1 |
| Gross, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Influence of Local Biopsy of the Endometrium Prior to Controlled Ovarian Stimulation for IVF or ICSI Procedure on the Rates of Embryo Implantation, Clinical Pregnancy and Live Birth in ART[NCT01064193] | Phase 3 | 190 participants (Actual) | Interventional | 2010-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for aspirin and Ovarian Hyperstimulation Syndrome
| Article | Year |
|---|---|
The role of platelets in reproduction
Topics: Aspirin; Blood Platelets; Female; Hemostasis; Humans; Ovarian Hyperstimulation Syndrome; Placenta; P | 2022 |
[Cerebral infarction after ovarian hyperstimulation in the era of thrombolysis].
Topics: Adult; Aspirin; Craniotomy; Drug Therapy, Combination; Fatal Outcome; Female; Fibrinolytic Agents; H | 2014 |
Prevention and management of ovarian hyperstimulation syndrome.
Topics: Aspirin; Calcium Gluconate; Cyclooxygenase Inhibitors; Disease Management; Dopamine Agonists; Female | 2017 |
[Controlled ovarian hyperstimulation (COH) and management of low-responder cases (HOO)].
Topics: Aromatase; Aromatase Inhibitors; Aspirin; Clinical Protocols; Female; Gonadotropin-Releasing Hormone | 2003 |
4 trials available for aspirin and Ovarian Hyperstimulation Syndrome
| Article | Year |
|---|---|
Effect of low-dose aspirin on the development of ovarian hyperstimulation syndrome and outcomes of assisted reproductive techniques in the women with PCOS, a randomized double-blinded clinical trial.
Topics: Adult; Aspirin; Double-Blind Method; Female; Fertilization in Vitro; Gonadotropin-Releasing Hormone; | 2019 |
Effect of letrozole on moderate and severe early-onset ovarian hyperstimulation syndrome in high-risk women: a prospective randomized trial.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aromatase Inhibitors; Ascites; Aspirin; Chorionic Go | 2017 |
Low-dose aspirin therapy to prevent ovarian hyperstimulation syndrome.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dose-Response Relationship, Drug; Female; F | 2010 |
Low-dose acetylsalicylic acid plus prednisolone as an adjuvant treatment in IVF: a prospective, randomized study.
Topics: Adult; Anti-Inflammatory Agents; Arteries; Aspirin; Embryo Implantation; Female; Fertility Agents, F | 2008 |
3 other studies available for aspirin and Ovarian Hyperstimulation Syndrome
| Article | Year |
|---|---|
Combining several interventions to reduce the incidence of OHSS: A prospective cohort study.
Topics: Adult; Aspirin; Cabergoline; Chorionic Gonadotropin; Drug Therapy, Combination; Ergolines; Female; G | 2017 |
Low-dose aspirin for prophylaxis of ovarian hyperstimulation syndrome.
Topics: Aspirin; Female; Fertilization in Vitro; Humans; Infertility; Ovarian Hyperstimulation Syndrome; Ovu | 2008 |
Prophylaxis of ovarian hyperstimulation syndrome.
Topics: Aspirin; Dopamine; Female; Humans; Ovarian Hyperstimulation Syndrome | 1992 |